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Most cited papers from Keio University

What are the most cited papers from Keio University?

The most cited paper from Keio University is "Initial sequencing and analysis of the human genome" (Eric S. Lander et al., 2001), with 24,745 citations. Next come "A molecular dynamics method for simulations in the canonical ensemble" (10,260) and "Construction of Escherichia coli K‐12 in‐frame, single‐gene knockout mutants: the Keio collection" (8,362).

Showing 50 of 59 papers. Every paper with more than 1,584 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Initial sequencing and analysis of the human genome Eric S. Lander et al. · Nature Open access252 authors Feb 2001 24,745
2 A molecular dynamics method for simulations in the canonical ensemble Shūichi Nosé · Molecular Physics 10 Jun 1984 10,260
3 Construction of Escherichia coli K‐12 in‐frame, single‐gene knockout mutants: the Keio collection Tomoya Baba, Takeshi Ara, Miki Launois Hasegawa et al. · Molecular Systems Biology Open access 21 Feb 2006 8,362
4 Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 Andrew Rhodes et al. · Intensive Care Medicine Open access 18 Jan 2017 6,868
5 Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Daniel J. Klionsky et al. · Autophagy Open access2,467 authors 2 Jan 2016 6,023
6 EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update Josef S Smolen et al. · Annals of the Rheumatic Diseases Open access 6 Mar 2017 5,808
7 Mersenne twister Makoto Matsumoto, Takuji Nishimura · ACM Transactions on Modeling and Computer Simulation 1998 5,805
8 Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells Yukihiro Furusawa et al. · Nature 13 Nov 2013 5,575
9 Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism Tohru Kitada, Shuichi Asakawa, Nobutaka Hattori et al. · Nature Apr 1998 5,278
10 Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips Juri Rappsilber, Matthias Mann, Yasushi Ishihama · Nature Protocols Aug 2007 5,019
11 The IASLC Lung Cancer Staging Project: Proposals for Revision of the TNM Stage Groupings in the Forthcoming (Eighth) Edition of the TNM Classification for Lung Cancer Peter Goldstraw et al. · Journal of Thoracic Oncology Open access152 authors 2016 4,749
12 Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice Taichi Hara, Kenji D. Nakamura, Makoto Matsui et al. · Nature 19 Apr 2006 3,905
13 The repertoire of mutational signatures in human cancer Ludmil B. Alexandrov et al. · Nature Open access1,384 authors 5 Feb 2020 3,854
14 A bacterium that degrades and assimilates poly(ethylene terephthalate) Shosuke Yoshida, Kazumi Hiraga, Toshihiko Takehana et al. · Science 10 Mar 2016 3,416
15 TFOS DEWS II Definition and Classification Report Jennifer P. Craig, Kelly Kinney Nichols, Esen K. Akpek et al. · The Ocular Surface Jul 2017 3,402
16 Pan-cancer analysis of whole genomes Lauri A. Aaltonen et al. · Nature Open access1,324 authors 5 Feb 2020 3,360
17 Fundamental analysis for visible-light communication system using LED lights Toshihiko Komine, Masaki Nakagawa · IEEE Transactions on Consumer Electronics Feb 2004 3,350
18 Biogenesis of small RNAs in animals V. Narry Kim, Jinju Han, Mikiko C. Siomi · Nature Reviews Molecular Cell Biology Review 23 Jan 2009 3,201
19 Cloning of adiponectin receptors that mediate antidiabetic metabolic effects Toshimasa Yamauchi et al. · Nature 11 Jun 2003 3,196
20 The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models Michael Hucka et al. · Bioinformatics Open access 28 Feb 2003 3,190
21 Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota Koji Atarashi et al. · Nature 9 Jul 2013 2,965
22 EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update Josef S Smolen et al. · Annals of the Rheumatic Diseases Open access 22 Jan 2020 2,807
23 NF-κB, inflammation, immunity and cancer: coming of age Koji Taniguchi, Michael Karin · Nature reviews. Immunology Review 22 Jan 2018 2,765
24 Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 Daniel J. Klionsky et al. · Autophagy Open access2,930 authors 2 Jan 2021 2,743
25 Cross-national prevalence and risk factors for suicidal ideation, plans and attempts Matthew K. Nock et al. · The British Journal of Psychiatry Open access 31 Jan 2008 2,701
26 TFOS DEWS II Epidemiology Report Fiona Jane Stapleton, Mônica Alves, Vatinee Y. Bunya et al. · The Ocular Surface Open access Jul 2017 2,656
27 MassBank: a public repository for sharing mass spectral data for life sciences Hisayuki Horai et al. · Journal of Mass Spectrometry Open access Jul 2010 2,595
28 Initial Invasive or Conservative Strategy for Stable Coronary Disease David Joel Maron et al. · New England Journal of Medicine Open access 30 Mar 2020 2,464
29 Traumatic spinal cord injury Christopher S. Ahuja, Jefferson R. Wilson, Satoshi Nori et al. · Nature Reviews Disease Primers Review 26 Apr 2017 2,463
30 Nivolumab in patients with advanced gastric or gastro-oesophageal junction cancer refractory to, or intolerant of, at least two previous chemotherapy regimens (ONO-4538-12, ATTRACTION-2): a randomised, double-blind, placebo-controlled, phase 3 trial Yoon‐Koo Kang et al. · The Lancet Open access 12 Oct 2017 2,317
31 Observation of the spin Seebeck effect Ken‐ichi Uchida, S. Takahashi, Kazuya Harii et al. · Nature Oct 2008 2,263
32 Direct observation of the rotation of F1-ATPase Hiroyuki Noji, Ryohei Yasuda, Masasuke Yoshida et al. · Nature Mar 1997 2,260
33 Stereotactic Radiosurgery Plus Whole-Brain Radiation Therapy vs Stereotactic Radiosurgery Alone for Treatment of Brain Metastases Hidefumi Aoyama, Hiroki Shirato, Masao Tago et al. · JAMA 6 Jun 2006 2,226
34 A promoter-level mammalian expression atlas Alistair R. R. Forrest et al. · Nature Open access261 authors Mar 2014 2,221
35 Conversion of spin current into charge current at room temperature: Inverse spin-Hall effect Eiji Saitoh, Masahito Ueda, H. Miyajima et al. · Applied Physics Letters May 2006 2,175
36 Innate Lymphoid Cells: 10 Years On Eric D. Vivier, David Artis, Marco Colonna et al. · Cell Open access Aug 2018 2,174
37 TFOS DEWS II Diagnostic Methodology report James S. Wolffsohn, Reiko Arita, Robin L. Chalmers et al. · The Ocular Surface Jul 2017 2,152
38 TAK1 is a ubiquitin-dependent kinase of MKK and IKK Chen Wang, Li Deng, Mei Hong et al. · Nature 19 Jul 2001 2,134
39 International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study Franck Pagès et al. · The Lancet May 2018 2,133
40 Violent video game effects on aggression, empathy, and prosocial behavior in Eastern and Western countries: A meta-analytic review. Craig A. Anderson, Akiko Shibuya, Nobuko Ihori et al. · Psychological Bulletin 2010 2,046
41 Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase Hideki Shimura, Nobutaka Hattori, Shinichiro Kubo et al. · Nature Genetics Jul 2000 2,029
42 Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells Kazuyo Moro, Taketo Yamada, M. Tanabe et al. · Nature 20 Dec 2009 2,003
43 A framework for quality management research and an associated measurement instrument Barbara Bechler Flynn, Roger G. Schroeder, Sadao Sakakibara · Journal of Operations Management Mar 1994 1,975
44 Tie2/Angiopoietin-1 Signaling Regulates Hematopoietic Stem Cell Quiescence in the Bone Marrow Niche Fumio Arai, Atsushi Hirao, Masako Ohmura et al. · Cell Open access Jul 2004 1,960
45 EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2022 update Josef S Smolen et al. · Annals of the Rheumatic Diseases Open access 10 Nov 2022 1,921
46 How mental health care should change as a consequence of the COVID-19 pandemic Carmen Moreno et al. · The Lancet Psychiatry Open access 16 Jul 2020 1,919
47 Cardiomyocytes can be generated from marrow stromal cells in vitro Shinji Makino, Keiichi Fukuda, Shunichirou Miyoshi et al. · Journal of Clinical Investigation Open access Mar 1999 1,889
48 Motion control for advanced mechatronics Kouhei Ohnishi, Mizuho Shibata, Toshiyuki Murakami · IEEE/ASME Transactions on Mechatronics Mar 1996 1,882
49 The microbiota in adaptive immune homeostasis and disease Kenya Honda, Dan R. Littman · Nature 5 Jul 2016 1,880
50 TFOS DEWS II pathophysiology report Anthony J. Bron, Cintia Sade de Paiva, Sunil K. Chauhan et al. · The Ocular Surface Jul 2017 1,822

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.