Most cited papers from Kirin (Japan)

Kirin (Japan)

What are the most cited papers from Kirin (Japan)?

The most cited paper from Kirin (Japan) is "A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD" (Masato Enari, Hideki Sakahira, Hideki Yokoyama et al., 1998), with 3,204 citations. Next come "Regulation of Myosin Phosphatase by Rho and Rho-Associated Kinase (Rho-Kinase)" (2,907) and "CD1d-Restricted and TCR-Mediated Activation of V α 14 NKT Cells by Glycosylceramides" (2,412).

Published TypeFieldAccessCitations

Showing 50 of 59 papers. Every paper with more than 321 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD Masato Enari, Hideki Sakahira, Hideki Yokoyama et al. · Nature	1998	3,204
2	Regulation of Myosin Phosphatase by Rho and Rho-Associated Kinase (Rho-Kinase) Kazushi Kimura, Masaaki Ito, Mutsuki Amano et al. · Science	12 Jul 1996	2,907
3	CD1d-Restricted and TCR-Mediated Activation of V α 14 NKT Cells by Glycosylceramides Tetsu Kawano, Junqing Cui, Yasuhiko Koezuka et al. · Science	28 Nov 1997	2,412
4	Klotho converts canonical FGF receptor into a specific receptor for FGF23 Itaru Urakawa, Yuji Yamazaki, Takashi Shimada et al. · Nature	29 Oct 2006	1,855
5	Signaling from Rho to the Actin Cytoskeleton Through Protein Kinases ROCK and LIM-kinase Midori Maekawa, Toshimasa Ishizaki, Shuken Boku et al. · Science	6 Aug 1999	1,651
6	Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia Takashi Shimada, SATORU MIZUTANI, Takanori Muto et al. · Proceedings of the National Academy of Sciences Open access	8 May 2001	1,465
7	Identification of a factor that links apoptotic cells to phagocytes Rikinari Hanayama, Masato Tanaka, Keiko Miwa et al. · Nature	May 2002	1,403
8	Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism Takashi Shimada, Makoto Kakitani, Y. Yamazaki et al. · Journal of Clinical Investigation Open access	15 Feb 2004	1,377
9	Tracking the Response of Natural Killer T Cells to a Glycolipid Antigen Using Cd1d Tetramers Jennifer L. Matsuda, Olga V. Naidenko, Laurent Gapin et al. · The Journal of Experimental Medicine Open access	5 Sep 2000	897
10	The small GTP‐binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase. Toshimaa Ishizaki, Midori Maekawa, Katsuki Fujisawa et al. · The EMBO Journal Open access	Apr 1996	891
11	Cutting Edge: Cross-Talk Between Cells of the Innate Immune System: NKT Cells Rapidly Activate NK Cells Claude Carnaud, Daniel C. Lee, Olivier Donnars et al. · The Journal of Immunology	Nov 1999	861
12	CRMP-2 binds to tubulin heterodimers to promote microtubule assembly Yuko Fukata, Tomohiko J. Itoh, Toshihide Kimura et al. · Nature Cell Biology	15 Jul 2002	772
13	BDCA-2, a Novel Plasmacytoid Dendritic Cell–specific Type II C-type Lectin, Mediates Antigen Capture and Is a Potent Inhibitor of Interferon α/β Induction Andrzej Dzionek, Yoshiaki Sohma, Jun Nagafune et al. · The Journal of Experimental Medicine Open access	17 Dec 2001	763
14	Omics-based identification of Arabidopsis Myb transcription factors regulating aliphatic glucosinolate biosynthesis Masami Yokota Hirai, Kenjiro Sugiyama, Yuji Sawada et al. · Proceedings of the National Academy of Sciences Open access	9 Apr 2007	757
15	Muscular Dystrophy and Neuronal Migration Disorder Caused by Mutations in a Glycosyltransferase, POMGnT1 Aruto Yoshida, Kazuhiro Kobayashi, Hiroshi Manya et al. · Developmental Cell Open access	Nov 2001	714
16	CD1d-mediated Recognition of an α-Galactosylceramide by Natural Killer T Cells Is Highly Conserved through Mammalian Evolution Laurent Brossay, Mariacristina Chioda, Nicolas Burdin et al. · The Journal of Experimental Medicine Open access	19 Oct 1998	651
17	Actin polymerization is induced by Arp 2/3 protein complex at the surface of Listeria monocytogenes Matthew D. Welch, Akihiro Iwamatsu, Timothy John Mitchison · Nature	1997	612
18	Elucidation of the Erwinia uredovora carotenoid biosynthetic pathway by functional analysis of gene products expressed in Escherichia coli Norihiko Misawa, Masaya Nakagawa, Kazuo Kobayashi et al. · Journal of Bacteriology Open access	Dec 1990	607
19	Activation of natural killer T cells by α-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes Shayan Sharif, Guillermo Arreaza, Peter Zucker et al. · Nature Medicine	Sep 2001	605
20	Rac1 and Cdc42 Capture Microtubules through IQGAP1 and CLIP-170 Masaki Fukata, Takashi Watanabe, Jun Noritake et al. · Cell Open access	Jun 2002	601
21	Structure-Activity Relationship of .alpha.-Galactosylceramides against B16-Bearing Mice Masahiro Morita, Kazuhiro Motoki, Kohji Akimoto et al. · Journal of Medicinal Chemistry	Jun 1995	596
22	Mitogenic Influence of Human R-Spondin1 on the Intestinal Epithelium Kyung‐Ah Kim, Makoto Kakitani, Jingsong Zhao et al. · Science	18 Aug 2005	592
23	Natural Killer T Cell Activation Inhibits Hepatitis B Virus Replication in Vivo Kazuhiro Kakimi, Luca G. Guidotti, Yasuhiko Koezuka et al. · The Journal of Experimental Medicine Open access	25 Sep 2000	586
24	The natural killer T-cell ligand α-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice Seokmann Hong, Michael T. Wilson, Isao Serizawa et al. · Nature Medicine	Sep 2001	550
25	Expression of Vascular Endothelial Growth Factors and Their Receptors during Osteoblast Differentiation Martine M. L. Deckers, Marcel Karperien, Chris van der Bent et al. · Endocrinology	May 2000	534
26	The Human Arp2/3 Complex Is Composed of Evolutionarily Conserved Subunits and Is Localized to Cellular Regions of Dynamic Actin Filament Assembly Matthew D. Welch, Angela H. DePace, Suzie Verma et al. · The Journal of Cell Biology Open access	28 Jul 1997	518
27	A phase I study of the natural killer T-cell ligand alpha-galactosylceramide (KRN7000) in patients with solid tumors. Giuseppe Giaccone, Cornelis J. A. Punt, Yoshitaka Ando et al. · PubMed	Dec 2002	507
28	Evaluation of transgenic tomato plants expressing an additional phytoene synthase in a fruit-specific manner Paul David Fraser, Susanne Römer, Cathie A. Shipton et al. · Proceedings of the National Academy of Sciences Open access	22 Jan 2002	488
29	Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Vα14 NKT cells Tetsu Kawano, Junqing Cui, Yasuhiko Koezuka et al. · Proceedings of the National Academy of Sciences Open access	12 May 1998	479
30	Murine CD1d-Restricted T Cell Recognition of Cellular Lipids Jenny E. Gumperz, Christopher J. Roy, Anna M. Makowska et al. · Immunity Open access	Feb 2000	474
31	Structure and functional analysis of a marine bacterial carotenoid biosynthesis gene cluster and astaxanthin biosynthetic pathway proposed at the gene level Norihiko Misawa, Y. Satomi, Keiji Kondô et al. · Journal of Bacteriology Open access	Nov 1995	460
32	Identification of a Novel Phosphorylation Site on Histone H3 Coupled with Mitotic Chromosome Condensation Hidemasa Goto, Hidetaka Kosako, Yasuko Tomono et al. · Journal of Biological Chemistry Open access	Sep 1999	460
33	A Novel Membrane Glycoprotein, SHPS-1, That Binds the SH2-Domain-Containing Protein Tyrosine Phosphatase SHP-2 in Response to Mitogens and Cell Adhesion Yohsuke Fujioka, Takashi Matozaki, Tetsuya Noguchi et al. · Molecular and Cellular Biology Open access	Dec 1996	453
34	Elevation of the provitamin A content of transgenic tomato plants Susanne Römer, Paul David Fraser, Joy W. Kiano et al. · Nature Biotechnology	Jun 2000	448
35	CD1d-restricted Recognition of Synthetic Glycolipid Antigens by Human Natural Killer T Cells Franca M. Spada, Yasuhiko Koezuka, Steven Anthony Porcelli · The Journal of Experimental Medicine Open access	19 Oct 1998	443
36	FGF-23 transgenic mice demonstrate hypophosphatemic rickets with reduced expression of sodium phosphate cotransporter type IIa Takashi Shimada, Itaru Urakawa, Y. Yamazaki et al. · Biochemical and Biophysical Research Communications	6 Jan 2004	432
37	Dietary and Genetic Control of Glucose Transporter 2 Glycosylation Promotes Insulin Secretion in Suppressing Diabetes Kazuaki Ohtsubo, Shinji Takamatsu, Mari Toba Minowa et al. · Cell Open access	Dec 2005	430
38	Dietary and Serum Phosphorus Regulate Fibroblast Growth Factor 23 Expression and 1,25-Dihydroxyvitamin D Metabolism in Mice Farzana Perwad, Nasreen Azam, Martin Y. H. Zhang et al. · Endocrinology	26 Aug 2005	429
39	Dietary Phosphorus Regulates Serum Fibroblast Growth Factor-23 Concentrations in Healthy Men Diana Mirella Antoniucci, Takeyoshi Yamashita, Anthony A. Portale · The Journal of Clinical Endocrinology & Metabolism	31 May 2006	422
40	Identification of a Putative Target for Rho as the Serine-Threonine Kinase Protein Kinase N Mutsuki Amano, Hideyuki Mukai, Yoshitaka Ono et al. · Science	2 Feb 1996	420
41	Sustained expansion of NKT cells and antigen-specific T cells after injection of α-galactosyl-ceramide loaded mature dendritic cells in cancer patients D. Chang, Keren Osman, John Edward Connolly et al. · The Journal of Experimental Medicine Open access	2 May 2005	416
42	Agelasphins, novel antitumor and immunostimulatory cerebrosides from the marine sponge Agelas mauritianus Takenori Natori, Masahiro Morita, Kohji Akimoto et al. · Tetrahedron	Feb 1994	399
43	Natural Killer T Cell Activation Protects Mice Against Experimental Autoimmune Encephalomyelitis Avneesh Kumar Singh, Michael T. Wilson, Seokmann Hong et al. · The Journal of Experimental Medicine Open access	17 Dec 2001	389
44	Loss of IFN-γ Production by Invariant NK T Cells in Advanced Cancer Syed Muhammad Tahir, Olivia Cheng, Angela Shaulov et al. · The Journal of Immunology	Oct 2001	386
45	EBI1/CCR7 Is a New Member of Dendritic Cell Chemokine Receptor That Is Up-Regulated upon Maturation Shigehiro Yanagihara, Emiko Komura, Jun Nagafune et al. · The Journal of Immunology	Sep 1998	375
46	Familial essential thrombocythemia associated with a dominant-positive activating mutation of the c-MPL gene, which encodes for the receptor for thrombopoietin Jianmin Ding, Hirokazu Komatsu, Atsushi Wakita et al. · Blood	9 Feb 2004	373
47	Polo-like kinase 1 phosphorylates cyclin B1 and targets it to the nucleus during prophase Fumiko Toyoshima, Eri Taniguchi, Nobuko Shinya et al. · Nature	8 Mar 2001	367
48	KRN7000, a novel immunomodulator, and its antitumor activities. Eiji Kobayashi, Kazuhiro Motoki, Takeshi Uchida et al. · PubMed	1995	364
49	Mammalian Lgl Forms a Protein Complex with PAR-6 and aPKC Independently of PAR-3 to Regulate Epithelial Cell Polarity Tomoyuki Yamanaka, Yosuke Horikoshi, Yuki Sugiyama et al. · Current Biology Open access	Apr 2003	362
50	Vitamin D receptor-independent FGF23 actions in regulating phosphate and vitamin D metabolism Takashi Shimada, Y. Yamazaki, Motoo Takahashi et al. · American Journal of Physiology-Renal Physiology	5 Jul 2005	359

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.