| 1 |
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Daniel J. Klionsky et al. · Autophagy
Open access2,467 authors |
2 Jan 2016 |
6,023 |
| 2 |
Serum Neurofilament light: A biomarker of neuronal damage in multiple sclerosis
Giulio Disanto, Christian Barro, Pascal Benkert et al. · Annals of Neurology
Open access |
16 May 2017 |
1,194 |
| 3 |
Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023
Simon I Hay et al. · The Lancet
Open access2,780 authors |
Oct 2025 |
762 |
| 4 |
Serum neurofilament light chain for individual prognostication of disease activity in people with multiple sclerosis: a retrospective modelling and validation study
Pascal Benkert et al. · The Lancet Neurology
Open access |
16 Feb 2022 |
643 |
| 5 |
Global burden of 292 causes of death in 204 countries and territories and 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023
Mohsen Naghavi et al. · The Lancet
Open access2,463 authors |
Oct 2025 |
500 |
| 6 |
Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation
Tariq Afroz, Eva‐Maria Hock, Patrick J. Ernst et al. · Nature Communications
Open access |
22 Jun 2017 |
358 |
| 7 |
The global, regional, and national burden of cancer, 1990–2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023
Lisa M Force et al. · The Lancet
Open access1,377 authors |
25 Sep 2025 |
330 |
| 8 |
Reelin Deficiency and Displacement of Mature Neurons, But Not Neurogenesis, Underlie the Formation of Granule Cell Dispersion in the Epileptic Hippocampus
Christophe Heinrich, Naoki Nitta, Armin Flubacher et al. · Journal of Neuroscience
Open access |
26 Apr 2006 |
308 |
| 9 |
The EANM practice guidelines for parathyroid imaging
Petra Petranović Ovčariček, Luca Giovanella, Ignasi Carrió Gasset et al. · European Journal of Nuclear Medicine and Molecular Imaging
Open access |
10 Apr 2021 |
307 |
| 10 |
Serum Glial Fibrillary Acidic Protein Compared With Neurofilament Light Chain as a Biomarker for Disease Progression in Multiple Sclerosis
Stephanie L. Meier et al. · JAMA Neurology
Open access |
6 Feb 2023 |
300 |
| 11 |
Characteristics and Outcomes in Patients With COVID-19 and Acute Ischemic Stroke
George Ntaios et al. · Stroke
Open access |
9 Jul 2020 |
287 |
| 12 |
ESO–ESMO 4th International Consensus Guidelines for Breast Cancer in Young Women (BCY4)
Shani Paluch–Shimon, Fátima Cardoso, Ann H. Partridge et al. · Annals of Oncology
Open access |
18 Mar 2020 |
259 |
| 13 |
Chronic sleep loss during pregnancy as a determinant of stress: impact on pregnancy outcome
Laura Palagini, Angelo Gemignani, Susanna Banti et al. · Sleep Medicine
|
27 May 2014 |
229 |
| 14 |
ER‐to‐lysosome‐associated degradation of proteasome‐resistant ATZ polymers occurs via receptor‐mediated vesicular transport
Ilaria Fregno, Elisa Fasana, Timothy Jan Bergmann et al. · The EMBO Journal
Open access |
3 Aug 2018 |
207 |
| 15 |
Pitfalls in electrodiagnosis of Guillain-Barre syndrome subtypes
Antonino Uncini, C. Manzoli, Francesca Notturno et al. · Journal of Neurology Neurosurgery & Psychiatry
Open access |
24 Sep 2010 |
197 |
| 16 |
A benchmarking tool to evaluate computer tomography perfusion infarct core predictions against a DWI standard
Carlo W. Cereda, Sören Christensen, Bruce C.V. Campbell et al. · Journal of Cerebral Blood Flow & Metabolism
Open access |
4 Dec 2015 |
195 |
| 17 |
Association of Brain Atrophy With Disease Progression Independent of Relapse Activity in Patients With Relapsing Multiple Sclerosis
Alessandro Cagol et al. · JAMA Neurology
Open access |
16 May 2022 |
188 |
| 18 |
Diagnosis and Treatment of Breast Cancer in Young Women
Lorenzo Rossi, Calogero Mazzara, Olivia Pagani · Current Treatment Options in Oncology
|
27 Nov 2019 |
186 |
| 19 |
Prodromal symptoms of multiple sclerosis in primary care
Giulio Disanto, Chiara Zecca, Sharon MacLachlan et al. · Annals of Neurology
|
9 May 2018 |
176 |
| 20 |
When gender matters: Restless legs syndrome. Report of the “RLS and woman” workshop endorsed by the European RLS Study Group
Mauro Manconi, Jan Ulfberg, Klaus Berger et al. · Sleep Medicine Reviews
|
10 Nov 2011 |
154 |
| 21 |
European guidelines on management of restless legs syndrome: report of a joint task force by the European Federation of Neurological Societies, the European Neurological Society and the European Sleep Research Society
Diego Garcı́a-Borreguero, Luigi Ferini‐Strambi, Ralf Kohnen et al. · European Journal of Neurology
Open access |
3 Sep 2012 |
153 |
| 22 |
Forecasting the effects of smoking prevalence scenarios on years of life lost and life expectancy from 2022 to 2050: a systematic analysis for the Global Burden of Disease Study 2021
Dana Bryazka et al. · The Lancet Public Health
Open access1,009 authors |
Oct 2024 |
148 |
| 23 |
Bitopertin in Negative Symptoms of Schizophrenia—Results From the Phase III FlashLyte and DayLyte Studies
Dragana Bugarski‐Kirola, Thomas Blaettler, Celso Arango et al. · Biological Psychiatry
|
15 Dec 2016 |
145 |
| 24 |
Prior Anticoagulation in Patients with Ischemic Stroke and Atrial Fibrillation
Thomas R. Meinel et al. · Annals of Neurology
Open access |
30 Sep 2020 |
142 |
| 25 |
EANM practice guideline for PET/CT imaging in medullary thyroid carcinoma
Luca Giovanella, Giorgio Treglia, Ιoannis Iakovou et al. · European Journal of Nuclear Medicine and Molecular Imaging
|
3 Sep 2019 |
141 |
| 26 |
Dissociation of periodic leg movements from arousals in restless legs syndrome
Mauro Manconi, Raffaele Ferri, Marco Zucconi et al. · Annals of Neurology
|
24 Feb 2012 |
133 |
| 27 |
Violence in sleep
Francesca Siclari, Ramin Khatami, Frank Urbaniok et al. · Brain
Open access |
30 Nov 2010 |
131 |
| 28 |
Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants
Thomas R. Meinel et al. · JAMA Neurology
Open access226 authors |
3 Jan 2023 |
125 |
| 29 |
Myofascial pain syndrome and trigger points: evaluation and treatment in patients with musculoskeletal pain
Marco Barbero, Alessandro Schneebeli, Eva Koetsier et al. · Current Opinion in Supportive and Palliative Care
|
15 Jul 2019 |
122 |
| 30 |
Dynamic prostate cancer transcriptome analysis delineates the trajectory to disease progression
Marco Bolis et al. · Nature Communications
Open access |
2 Dec 2021 |
121 |
| 31 |
Rapid Musculoskeletal MRI in 2021: Clinical Application of Advanced Accelerated Techniques
Jan Marie Fritz, Roman Guggenberger, Filippo Del Grande · American Journal of Roentgenology
|
3 Feb 2021 |
120 |
| 32 |
Influence of the topography of brain damage on depression and fatigue in patients with multiple sclerosis
Claudio Gobbi, Maria Assunta Rocca, Gianna Carla Riccitelli et al. · Multiple Sclerosis Journal
|
27 Jun 2013 |
119 |
| 33 |
Antiganglioside antibodies are associated with axonal Guillain–Barré syndrome: A Japanese–Italian collaborative study
Yukari Sekiguchi, Antonino Uncini, Nobuhiro Yuki et al. · Journal of Neurology Neurosurgery & Psychiatry
|
18 Oct 2011 |
119 |
| 34 |
Sleep Disturbance Impairs Stroke Recovery in the Rat
Cristina Zunzunegui, Bo Gao, Ertugrul Cam et al. · SLEEP
Open access |
Sep 2011 |
118 |
| 35 |
Guillain–Barré syndrome associated with normal or exaggerated tendon reflexes
Nobuhiro Yuki, Norito Kokubun, Satoshi Kuwabara et al. · Journal of Neurology
|
5 Dec 2011 |
115 |
| 36 |
Serum neurofilament light chain in patients with acute cerebrovascular events
Gian Marco De Marchis, Mira Katan, Christian Barro et al. · European Journal of Neurology
Open access |
27 Dec 2017 |
114 |
| 37 |
Fatigue and excessive daytime sleepiness in idiopathic Parkinson’s disease differently correlate with motor symptoms, depression and dopaminergic treatment
Philipp O. Valko, Daniel Waldvogel, Michael Weller et al. · European Journal of Neurology
|
14 May 2010 |
113 |
| 38 |
Chronic Insomnia: Clinical and Research Challenges - An Agenda
Dieter Wilhelm Riemann, Kai Spiegelhalder, Colin Alexander Espie et al. · Pharmacopsychiatry
|
15 Dec 2010 |
112 |
| 39 |
Simulating and stimulating performance: introducing distributed simulation to enhance musical learning and performance
Aaron Williamon, Lisa Aufegger, Hubert Eiholzer · Frontiers in Psychology
Open access |
2014 |
109 |
| 40 |
Circulating extracellular vesicles are endowed with enhanced procoagulant activity in SARS-CoV-2 infection
Carolina Balbi, Jacopo Burrello, Sara Bolis et al. · EBioMedicine
Open access |
May 2021 |
104 |
| 41 |
Neurofilament Light Chain Elevation and Disability Progression in Multiple Sclerosis
Ahmed Abdelhak et al. · JAMA Neurology
Open access |
6 Nov 2023 |
101 |
| 42 |
Aetiology, secondary prevention strategies and outcomes of ischaemic stroke despite oral anticoagulant therapy in patients with atrial fibrillation
Alexandros A. Polymeris et al. · Journal of Neurology Neurosurgery & Psychiatry
Open access |
8 Apr 2022 |
101 |
| 43 |
The paradox of paradoxical insomnia: A theoretical review towards a unifying evidence-based definition
Anna Castelnovo, Raffaele Ferri, Naresh M. Punjabi et al. · Sleep Medicine Reviews
|
24 Dec 2018 |
100 |
| 44 |
Profiling the Location and Extent of Musicians’ Pain Using Digital Pain Drawings
Cinzia Cruder, Deborah Falla, Francesca Mangili et al. · Pain Practice
Open access |
3 May 2017 |
100 |
| 45 |
Response to endovascular reperfusion is not time-dependent in patients with salvageable tissue
Maarten G. Lansberg et al. · Neurology
Open access |
29 Jul 2015 |
99 |
| 46 |
Global, regional, and national burden of headache disorders, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023
Andreas Kattem Hus⊘y et al. · The Lancet Neurology
Open access336 authors |
13 Nov 2025 |
98 |
| 47 |
Clinical trials in REM sleep behavioural disorder: challenges and opportunities
Aleksandar Videnović, Yo‐El S. Ju, Isabelle Arnulf et al. · Journal of Neurology Neurosurgery & Psychiatry
Open access |
13 May 2020 |
98 |
| 48 |
Narcolepsy: autoimmunity, effector T cell activation due to infection, or T cell independent, major histocompatibility complex class II induced neuronal loss?
A. Fontana, Heidemarie Gast, Walter Reith et al. · Brain
Open access |
19 Apr 2010 |
98 |
| 49 |
Middle Meningeal Artery: Anatomy and Variations
Sara Bonasia, Stanislas Smajda, Gabriele Cicciò et al. · American Journal of Neuroradiology
Open access |
3 Sep 2020 |
97 |
| 50 |
How do we recognize the child with OSAS?
Koen F. M. Joosten, Helena Larramona, Silvia Miano et al. · Pediatric Pulmonology
Open access |
16 Nov 2016 |
96 |