| 1 |
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
MAGIC et al. · Nature Genetics
Open access376 authors |
10 Oct 2010 |
2,999 |
| 2 |
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
Georg Ehret et al. · Nature
Open access346 authors |
9 Sep 2011 |
2,085 |
| 3 |
Hundreds of variants clustered in genomic loci and biological pathways affect human height
Hana Lango Allen et al. · Nature
Open access293 authors |
29 Sep 2010 |
2,063 |
| 4 |
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
MAGIC et al. · Nature Genetics
301 authors |
10 Oct 2010 |
965 |
| 5 |
First cases of coronavirus disease 2019 (COVID-19) in the WHO European Region, 24 January to 21 February 2020
Gianfranco Spiteri et al. · Eurosurveillance
Open access |
5 Mar 2020 |
714 |
| 6 |
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function
Cristian Pattaro et al. · Nature Communications
Open access700 authors |
21 Jan 2016 |
547 |
| 7 |
Parkinsonism, premature menopause, and mitochondrial DNA polymerase γ mutations: clinical and molecular genetic study
Petri T. Luoma, Atle Melberg, Juha O. Rinne et al. · The Lancet
|
Sep 2004 |
547 |
| 8 |
Incidence, risk factors and 90-day mortality of patients with acute kidney injury in Finnish intensive care units: the FINNAKI study
The FINNAKI Study Group, Sara Nisula, Kirsi‐Maija Kaukonen et al. · Intensive Care Medicine
|
4 Jan 2013 |
465 |
| 9 |
The Built Environment as a Determinant of Physical Activity: A Systematic Review of Longitudinal Studies and Natural Experiments
Mikko Kärmeniemi, Tiina Lankila, Tiina Maria Ikäheimo et al. · Annals of Behavioral Medicine
Review |
17 Jan 2018 |
455 |
| 10 |
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure
LifeLines Cohort Study et al. · Nature Genetics
Open access226 authors |
11 Sep 2011 |
447 |
| 11 |
Insulin glargine or NPH combined with metformin in type 2 diabetes: the LANMET study
Hannele Yki-Järvinen, R. Kauppinen-Mäkelin, Mirja Tiikkainen et al. · Diabetologia
Open access |
2 Feb 2006 |
439 |
| 12 |
Comparison of Bedtime Insulin Regimens in Patients with Type 2 Diabetes Mellitus
Hannele Yki‐Järvinen, Leena Ryysy, Kati Nikkilä et al. · Annals of Internal Medicine
|
2 Mar 1999 |
436 |
| 13 |
New gene functions in megakaryopoiesis and platelet formation
Christian Gieger et al. · Nature
Open access163 authors |
29 Nov 2011 |
429 |
| 14 |
Global developments in social prescribing
Daniel F Morse et al. · BMJ Global Health
Open access |
May 2022 |
390 |
| 15 |
Genetic evidence of assortative mating in humans
Matthew R. Robinson et al. · Nature Human Behaviour
533 authors |
9 Jan 2017 |
371 |
| 16 |
Short QT syndrome: clinical findings and diagnostic-therapeutic implications
Carla Giustetto, F. Di Monte, Christian Wolpert et al. · European Heart Journal
Open access |
22 Aug 2006 |
344 |
| 17 |
Comparison of Insulin Regimens in Patients with Non-Insulin-Dependent Diabetes Mellitus
Hannele Yki‐Järvinen, Marjut Kauppila, Eila Kujansuu et al. · New England Journal of Medicine
Open access |
12 Nov 1992 |
327 |
| 18 |
Long-Term Follow-Up of Patients With Short QT Syndrome
Carla Giustetto, Rainer Schimpf, Andrea Mazzanti et al. · Journal of the American College of Cardiology
Open access |
27 Jul 2011 |
326 |
| 19 |
Amyotrophic lateral sclerosis associated with homozygosity for an Asp90Ala mutation in CuZn-superoxide dismutase
Peter Munch Andersen, Peter Nilsson, V. Ala‐Hurula et al. · Nature Genetics
|
May 1995 |
323 |
| 20 |
Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders
Marcel den Hoed et al. · Nature Genetics
Open access268 authors |
14 Apr 2013 |
323 |
| 21 |
Expression and Regulation of Xenobiotic-Metabolizing Cytochrome P450 (CYP) Enzymes in Human Lung
Janne Hukkanen, Olavi Pelkonen, Jukka Hakkola et al. · Critical Reviews in Toxicology
|
2002 |
318 |
| 22 |
Mutations in the tyrosine phosphatase CD45 gene in a child with severe combined immunodeficiency disease
Chun Kung, Jeanette T. Pingel, Markku Heikinheimo et al. · Nature Medicine
|
Mar 2000 |
314 |
| 23 |
Serological and molecular findings during SARS-CoV-2 infection: the first case study in Finland, January to February 2020
Anu Haveri et al. · Eurosurveillance
Open access |
19 Mar 2020 |
287 |
| 24 |
Autosomal recessive adult-onset amyotrophic lateral sclerosis associated with homozygosity for Asp90Ala CuZn-superoxide dismutase mutation: A clinical and genealogical study of 36 patients
Peter Munch Andersen, Lars Forsgren, Michael Binzer et al. · Brain
|
Aug 1996 |
270 |
| 25 |
Drug-coated balloon for treatment of de-novo coronary artery lesions in patients with high bleeding risk (DEBUT): a single-blind, randomised, non-inferiority trial
Tuomas T. Rissanen, Sanna Uskela, Jaakko Eränen et al. · The Lancet
|
13 Jun 2019 |
255 |
| 26 |
Hemodynamic variables and progression of acute kidney injury in critically ill patients with severe sepsis: data from the prospective observational FINNAKI study
Meri Poukkanen, Erika Wilkman, Suvi T. Vaara et al. · Critical Care
Open access |
13 Dec 2013 |
212 |
| 27 |
Mutations in mRNA export mediator GLE1 result in a fetal motoneuron disease
Heidi O. Nousiainen, Marjo Kestilä, Niklas A. Pakkasjärvi et al. · Nature Genetics
Open access |
20 Jan 2008 |
203 |
| 28 |
Infant motor development is associated with adult cognitive categorisation in a longitudinal birth cohort study
Graham K. Murray, Juha M. Veijola, K. Moilanen et al. · Journal of Child Psychology and Psychiatry
|
21 Mar 2005 |
182 |
| 29 |
Cardiorespiratory Fitness Is Related to the Risk of Sudden Cardiac Death
Jari A. Laukkanen, Timo Heikki Mäkikallio, Rainer Rauramaa et al. · Journal of the American College of Cardiology
Open access |
Oct 2010 |
178 |
| 30 |
Postoperative symptoms at home following day‐case surgery in children: a multicentre survey of 551 children
LEENA H. KOTINIEMI, P Ryhänen, Jukka V. I. Valanne et al. · Anaesthesia
|
Oct 1997 |
177 |
| 31 |
DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes
Gerard W. Dougherty et al. · American Journal of Respiratory Cell and Molecular Biology
Open access |
24 Feb 2016 |
170 |
| 32 |
Bronchiectasis: an orphan disease with a poorly-understood prognosis
Timo Keistinen, Olli Säynäjäkangas, Tuili Tuuponen et al. · European Respiratory Journal
Open access |
Dec 1997 |
168 |
| 33 |
Dyslipidaemia as a predictor of hypertension in middle-aged men
David Elliot Laaksonen, LEO K. NISKANEN, K. Nyyssönen et al. · European Heart Journal
Open access |
29 Feb 2008 |
161 |
| 34 |
Duration of QRS Complex in Resting Electrocardiogram Is a Predictor of Sudden Cardiac Death in Men
Sudhir Kurl, Timo Heikki Mäkikallio, Pentti M. Rautaharju et al. · Circulation
Open access |
22 May 2012 |
160 |
| 35 |
Acute kidney injury in patients with severe sepsis in F innish I ntensive C are U nits
Meri Poukkanen, Suvi T. Vaara, Ville Pettilä et al. · Acta Anaesthesiologica Scandinavica
|
28 May 2013 |
149 |
| 36 |
Therapeutic hypothermia after out-of-hospital cardiac arrest in Finnish intensive care units: the FINNRESUSCI study
the FINNRESUSCI Study Group, Jukka Vaahersalo, Pamela Hiltunen et al. · Intensive Care Medicine
|
15 Feb 2013 |
144 |
| 37 |
Individual differences in the responses to endurance and resistance training
Arto Jorma Hautala, Antti M. Kiviniemi, Timo Heikki Mäkikallio et al. · European Journal of Applied Physiology
|
20 Dec 2005 |
143 |
| 38 |
Incidence trends of pediatric inflammatory bowel disease in Finland, 1987–2003, a nationwide study
Pieta Lehtinen, Merja H. Ashorn, Sari Iltanen et al. · Inflammatory Bowel Diseases
Open access |
15 Nov 2010 |
142 |
| 39 |
Remifentanil in Obstetric Analgesia: A Dose-Finding Study
P. Volmanen, Ethem I. Akural, Tytti Raudaskoski et al. · Anesthesia & Analgesia
|
Apr 2002 |
142 |
| 40 |
Cardiorespiratory fitness and risk of heart failure: a population‐based follow‐up study
Hassan Khan, Setor K. Kunutsor, Rainer Rauramaa et al. · European Journal of Heart Failure
|
14 Dec 2013 |
136 |
| 41 |
Occupational asthma due to stainless steel welding fumes
Helena Keskinen, P.‐L. Kalliomäki, K Alanko · Clinical & Experimental Allergy
|
Mar 1980 |
128 |
| 42 |
Two subphenotypes of septic acute kidney injury are associated with different 90-day mortality and renal recovery
Renske Wiersema, Sakari Jukarainen, Suvi T. Vaara et al. · Critical Care
Open access |
15 Apr 2020 |
127 |
| 43 |
Determinants of Cardiorespiratory Fitness in Men Aged 42 to 60 Years With and Without Cardiovascular Disease
Jari A. Laukkanen, David Elliot Laaksonen, Timo Antero Lakka et al. · The American Journal of Cardiology
|
23 Apr 2009 |
127 |
| 44 |
Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy
John F. O’Toole et al. · Journal of Clinical Investigation
Open access |
23 Feb 2010 |
123 |
| 45 |
AUDIT and AUDIT-C as screening instruments for alcohol problem use in adolescents
Joni Liskola, Henna Haravuori, Nina Ellefsen Lindberg et al. · Drug and Alcohol Dependence
Open access |
19 May 2018 |
122 |
| 46 |
Fibrin glue for preventing immediate postoperative hypotony following glaucoma drainage implant surgery
Juha Välimäki · Acta Ophthalmologica Scandinavica
Open access |
23 Apr 2006 |
121 |
| 47 |
Effect of Obesity on the Response to Insulin Therapy in Noninsulin-Dependent Diabetes Mellitus
Hannele Yki‐Järvinen, Leena Ryysy, Marjut Kauppila et al. · The Journal of Clinical Endocrinology & Metabolism
|
Dec 1997 |
119 |
| 48 |
Drainage is of no use in primary uncomplicated cemented hip and knee arthroplasty for osteoarthritis
R Niskanen, Olli Korkala, Jussi Haapala et al. · The Journal of Arthroplasty
|
Aug 2000 |
119 |
| 49 |
Intravenous remifentanil vs. epidural levobupivacaine with fentanyl for pain relief in early labour: a randomised, controlled, double‐blinded study
P. Volmanen, Johanna Sarvela, Ethem I. Akural et al. · Acta Anaesthesiologica Scandinavica
|
15 Nov 2007 |
119 |
| 50 |
Comparison of remifentanil and nitrous oxide in labour analgesia
P. Volmanen, Ethem I. Akural, Tytti Raudaskoski et al. · Acta Anaesthesiologica Scandinavica
|
17 Mar 2005 |
115 |