Most cited papers from Life Science Zurich

Life Science Zurich

What are the most cited papers from Life Science Zurich?

The most cited paper from Life Science Zurich is "MissForest—non-parametric missing value imputation for mixed-type data" (Daniel Johannes Stekhoven, Peter Bühlmann, 2011), with 6,389 citations. Next come "Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry" (2,072) and "An Immune Atlas of Clear Cell Renal Cell Carcinoma" (1,059).

Published TypeFieldAccessAuthorsCitations

Showing 50 of 60 papers. Every paper with more than 226 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	MissForest—non-parametric missing value imputation for mixed-type data Daniel Johannes Stekhoven, Peter Bühlmann · Bioinformatics Open access	28 Oct 2011	6,389
2	Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry Charlotte Giesen, Hao A. O. Wang, Denis Schapiro et al. · Nature Methods	2 Mar 2014	2,072
3	An Immune Atlas of Clear Cell Renal Cell Carcinoma Stéphane Chevrier, Jacob Levine, Vito Riccardo Tomaso Zanotelli et al. · Cell Open access	May 2017	1,059
4	The single-cell pathology landscape of breast cancer Hartland Warren Jackson, Jana Raja Fischer, Vito Riccardo Tomaso Zanotelli et al. · Nature Open access	20 Jan 2020	1,013
5	A Single-Cell Atlas of the Tumor and Immune Ecosystem of Human Breast Cancer Johanna Wagner, Maria Anna Rapsomaniki, Stéphane Chevrier et al. · Cell Open access	11 Apr 2019	854
6	OpenSWATH enables automated, targeted analysis of data-independent acquisition MS data Hannes Luc Röst, George Rosenberger, Pedro J. Navarro et al. · Nature Biotechnology Open access	Mar 2014	846
7	Wntless, a Conserved Membrane Protein Dedicated to the Secretion of Wnt Proteins from Signaling Cells Carla Bänziger, Davide Soldini, Corina Schütt et al. · Cell Open access	May 2006	797
8	histoCAT: analysis of cell phenotypes and interactions in multiplex image cytometry data Denis Schapiro, Hartland Warren Jackson, Swetha Raghuraman et al. · Nature Methods Open access	7 Aug 2017	745
9	Systematic evaluation of objective functions for predicting intracellular fluxes in Escherichia coli Robert J. Schuetz, Lars Kuepfer, Uwe Sauer · Molecular Systems Biology Open access	10 Jul 2007	706
10	Weed suppression greatly increased by plant diversity in intensively managed grasslands: A continental‐scale experiment John Connolly et al. · Journal of Applied Ecology Open access	10 Aug 2017	672
11	Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry Ben C. Collins et al. · Nature Communications Open access	10 Aug 2017	628
12	MorphoGraphX: A platform for quantifying morphogenesis in 4D Pierre Barbier de Reuille et al. · eLife Open access	6 May 2015	617
13	Multiplexed protein maps link subcellular organization to cellular states Gabriele Gut, Markus D. Herrmann, Lucas Pelkmans · Science	3 Aug 2018	575
14	muscat detects subpopulation-specific state transitions from multi-sample multi-condition single-cell transcriptomics data Helena Lucia Crowell, Charlotte Soneson, Pierre‐Luc Germain et al. · Nature Communications Open access	30 Nov 2020	529
15	A Mass Spectrometric-Derived Cell Surface Protein Atlas Damaris Bausch‐Fluck, Andreas Hofmann, Thomas Bock et al. · PLoS ONE Open access	20 Apr 2015	488
16	Structure of PTB Bound to RNA: Specific Binding and Implications for Splicing Regulation Florian C. Oberstrass, Sigrid Auweter, Michèle C. Erat et al. · Science Open access	22 Sep 2005	477
17	Compensation of Signal Spillover in Suspension and Imaging Mass Cytometry Stéphane Chevrier, Helena Lucia Crowell, Vito Riccardo Tomaso Zanotelli et al. · Cell Systems Open access	28 Mar 2018	465
18	Phase separation of 53BP1 determines liquid‐like behavior of DNA repair compartments Sinan Kilic, Aleksandra Lezaja, Marco Gatti et al. · The EMBO Journal Open access	Jul 2019	461
19	Cell-wide analysis of protein thermal unfolding reveals determinants of thermostability Pascal Leuenberger, Stefan Ganscha, Abdullah Kahraman et al. · Science	23 Feb 2017	453
20	High-Throughput, Accurate Mass Metabolome Profiling of Cellular Extracts by Flow Injection–Time-of-Flight Mass Spectrometry Tobias Fuhrer, Dominik Heer, Boris Begemann et al. · Analytical Chemistry Open access	10 Aug 2011	453
21	Kinase-controlled phase transition of membraneless organelles in mitosis Arpan Kumar Rai, Jia‐Xuan Chen, Matthias Selbach et al. · Nature Open access	Jul 2018	429
22	Population context determines cell-to-cell variability in endocytosis and virus infection Berend Snijder, Raphael Sacher, Pauli Rämö et al. · Nature	26 Aug 2009	426
23	LINC Complexes Form by Binding of Three KASH Peptides to Domain Interfaces of Trimeric SUN Proteins Brian A Sosa, Andrea Rothballer, Ulrike Kutay et al. · Cell Open access	May 2012	421
24	Cancer-associated fibroblast classification in single-cell and spatial proteomics data Lena Cords, Sandra Tietscher, Tobias Anzeneder et al. · Nature Communications Open access	18 Jul 2023	412
25	GLI1-expressing mesenchymal cells form the essential Wnt-secreting niche for colon stem cells Bahar Değirmenci, Tomáš Valenta, Slavica Dimitrieva et al. · Nature	Jun 2018	401
26	Acute Activation of Oxidative Pentose Phosphate Pathway as First-Line Response to Oxidative Stress in Human Skin Cells Andreas Kuehne, Hila Emmert, Joern Soehle et al. · Molecular Cell Open access	17 Jul 2015	399
27	Anthoceros genomes illuminate the origin of land plants and the unique biology of hornworts Fay‐Wei Li et al. · Nature Plants Open access	13 Mar 2020	394
28	Proteome-wide Identification of Poly(ADP-Ribosyl)ation Targets in Different Genotoxic Stress Responses Stephanie Jungmichel, Florian Rosenthal, Matthias Altmeyer et al. · Molecular Cell Open access	19 Sep 2013	389
29	Control of Transcript Variability in Single Mammalian Cells Nico Battich, Thomas Stoeger, Lucas Pelkmans · Cell Open access	Dec 2015	387
30	SIRT2 regulates NF-κB-dependent gene expression through deacetylation of p65 Lys310 Karin Rothgiesser, Süheda Erener, Susanne Waibel et al. · Journal of Cell Science Open access	16 Nov 2010	377
31	Condition-Dependent Cell Volume and Concentration of Escherichia coli to Facilitate Data Conversion for Systems Biology Modeling Benjamin Volkmer, Matthias Heinemann · PLoS ONE Open access	29 Jul 2011	372
32	Poly(ADP-Ribose) Polymerase 1 Participates in the Phase Entrainment of Circadian Clocks to Feeding Gad Asher, Hans Reinke, Matthias Altmeyer et al. · Cell Open access	Sep 2010	342
33	Genome-wide Mapping of Transcriptional Start Sites Defines an Extensive Leaderless Transcriptome in Mycobacterium tuberculosis Teresa Cortes, Olga T. Schubert, Graham Rose et al. · Cell Reports Open access	Nov 2013	336
34	Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites Matthias Altmeyer, Simon Messner, Paul O. Hassa et al. · Nucleic Acids Research Open access	16 Apr 2009	334
35	A Map of Human Type 1 Diabetes Progression by Imaging Mass Cytometry Nicolas Damond, Stefanie Engler, Vito Riccardo Tomaso Zanotelli et al. · Cell Metabolism Open access	31 Jan 2019	325
36	Cross-Platform Comparison of Methods for Quantitative Metabolomics of Primary Metabolism Jörg Martin Büscher, Dominika Czernik, Jennifer Christina Ewald et al. · Analytical Chemistry	23 Feb 2009	323
37	Arabidopsis Female Gametophyte Gene Expression Map Reveals Similarities between Plant and Animal Gametes Samuel E. Wuest, Kitty Vijverberg, Anja Schmidt et al. · Current Biology Open access	Mar 2010	322
38	Sequence-specific binding of single-stranded RNA: is there a code for recognition? Sigrid Auweter, Florian C. Oberstrass, Frédéric H.‐T. Allain · Nucleic Acids Research Open access	18 Sep 2006	320
39	Phosphoproteomic Analysis Reveals Interconnected System-Wide Responses to Perturbations of Kinases and Phosphatases in Yeast Bernd Bodenmiller et al. · Science Signaling Open access	21 Dec 2010	317
40	Reconstructing de novo silencing of an active plant retrotransposon Arturo Marí‐Ordóñez, Antonin Marchais, Mathilde Etcheverry et al. · Nature Genetics	14 Jul 2013	307
41	Endothelin and endothelin antagonists in chronic kidney disease Donald E. Kohan, Matthias Barton · Kidney International Open access	7 May 2014	307
42	Lysine-specific chemical cross-linking of protein complexes and identification of cross-linking sites using LC-MS/MS and the xQuest/xProphet software pipeline Alexander Leitner, Thomas Walzthoeni, Ruedi Aebersold · Nature Protocols	19 Dec 2013	305
43	Cancer-associated fibroblast phenotypes are associated with patient outcome in non-small cell lung cancer Lena Cords, Stefanie Engler, Martina Haberecker et al. · Cancer Cell Open access	18 Jan 2024	300
44	Simultaneous Multiplexed Imaging of mRNA and Proteins with Subcellular Resolution in Breast Cancer Tissue Samples by Mass Cytometry Daniel Schulz, Vito Riccardo Tomaso Zanotelli, Jana Raja Fischer et al. · Cell Systems Open access	27 Dec 2017	300
45	“They” are old but “I” feel younger: Age-group dissociation as a self-protective strategy in old age. David J. Weiss, Frieder R. Lang · Psychology and Aging Open access	11 Oct 2011	299
46	Image-based transcriptomics in thousands of single human cells at single-molecule resolution Nico Battich, Thomas Stoeger, Lucas Pelkmans · Nature Methods	6 Oct 2013	297
47	A comprehensive examination of Nanopore native RNA sequencing for characterization of complex transcriptomes Charlotte Soneson, Yao Yao, Anna Bratus-Neuenschwander et al. · Nature Communications Open access	31 Jul 2019	293
48	An end-to-end workflow for multiplexed image processing and analysis Jonas Windhager, Vito Riccardo Tomaso Zanotelli, Daniel Schulz et al. · Nature Protocols	10 Oct 2023	286
49	Arctic patterned‐ground ecosystems: A synthesis of field studies and models along a North American Arctic Transect Donald A. Walker et al. · Journal of Geophysical Research Atmospheres Open access	14 Jun 2008	278
50	PARP1 ADP-ribosylates lysine residues of the core histone tails Simon Messner, Matthias Altmeyer, Hongtao Zhao et al. · Nucleic Acids Research Open access	4 Jun 2010	269

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.