Most cited papers from Medicina
What are the most cited papers from Medicina?
The most cited paper from Medicina is "GW190521: A Binary Black Hole Merger with a Total Mass of 150 M ⊙" (R. Abbott et al., 2020), with 1,354 citations. Next come "Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safety Profiles for Food, Pharmaceutical, Biotechnological and Medicinal Applications" (1,034) and "Modular Organization of Genes Required for Complex Polyketide Biosynthesis" (914).
Showing 50 of 60 papers. Every paper with more than 147 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | GW190521: A Binary Black Hole Merger with a Total Mass of 150 M ⊙ R. Abbott et al. · Physical Review Letters | 2 Sep 2020 | 1,354 |
| 2 | Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safety Profiles for Food, Pharmaceutical, Biotechnological and Medicinal Applications Javad Sharifi‐Rad et al. · Frontiers in Pharmacology | 15 Sep 2020 | 1,034 |
| 3 | Modular Organization of Genes Required for Complex Polyketide Biosynthesis Stefano Donadio, Michael J. Staver, James B. McAlpine et al. · Science | 3 May 1991 | 914 |
| 4 | Accelerated reaction of nitric oxide with O 2 within the hydrophobic interior of biological membranes Xiaoping Liu, Mark J.S. Miller, Mahesh S. Joshi et al. · Proceedings of the National Academy of Sciences | 3 Mar 1998 | 600 |
| 5 | Recent advances in employing homoenolates generated by N-heterocyclic carbene (NHC) catalysis in carbon–carbon bond-forming reactions Rajeev S. Menon, Akkattu T. Biju, Vijay Nair · Chemical Society Reviews | 2015 | 597 |
| 6 | 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology Classification Criteria for Eosinophilic Granulomatosis with Polyangiitis Peter C. Grayson et al. · Annals of the Rheumatic Diseases | 2 Feb 2022 | 556 |
| 7 | Generic GPCR residue numbers – aligning topology maps while minding the gaps Vignir Ísberg, Chris de Graaf, Andrea Bortolato et al. · Trends in Pharmacological Sciences | 22 Dec 2014 | 518 |
| 8 | Defining Desirable Central Nervous System Drug Space through the Alignment of Molecular Properties, in Vitro ADME, and Safety Attributes Travis T. Wager, Ramalakshmi Yegna Chandrasekaran, Xinjun Hou et al. · ACS Chemical Neuroscience | 25 Mar 2010 | 492 |
| 9 | p185HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor. R M Hudziak, G D Lewis, M Winget et al. · Molecular and Cellular Biology | Mar 1989 | 489 |
| 10 | A mechanism for slow release of biomagnified cyanobacterial neurotoxins and neurodegenerative disease in Guam Susan J. Murch, Paul Alan Cox, Sandra Anne Banack · Proceedings of the National Academy of Sciences | 4 Aug 2004 | 417 |
| 11 | Twenty-year trends in the prevalence of Down syndrome and other trisomies in Europe: impact of maternal age and prenatal screening Maria A. Loane et al. · European Journal of Human Genetics | 20 Jun 2012 | 377 |
| 12 | Fructose-induced metabolic syndrome is associated with glomerular hypertension and renal microvascular damage in rats Laura Gabriela Sánchez‐Lozada, Edilia Tapia, Adriana Jiménez et al. · American Journal of Physiology-Renal Physiology | 30 Aug 2006 | 356 |
| 13 | Nitric oxide regulates angiogenesis through a functional switch involving thrombospondin-1 Lisa A. Ridnour, Jeffrey Scott Isenberg, Michael Graham Espey et al. · Proceedings of the National Academy of Sciences | 2 Sep 2005 | 323 |
| 14 | Identification of Cytochrome P450 2E1 as the Predominant Enzyme Catalyzing Human Liver Microsomal Defluorination of Sevoflurane, Isoflurane, and Methoxyflurane Evan D. Kharasch, Kenneth E. Thummel · Anesthesiology | Oct 1993 | 318 |
| 15 | Epidemiology of congenital diaphragmatic hernia in Europe: a register-based study M McGivern et al. · Archives of Disease in Childhood Fetal & Neonatal | 19 Nov 2014 | 317 |
| 16 | Role of oxidative stress in the renal abnormalities induced by experimental hyperuricemia Laura Gabriela Sánchez‐Lozada, Virgilia Soto, Edilia Tapia et al. · American Journal of Physiology-Renal Physiology | Oct 2008 | 309 |
| 17 | Late-stage [ 18 F]fluorination: new solutions to old problems Allen F. Brooks, Joseph J. Topczewski, Naoko Ichiishi et al. · Chemical Science | 2014 | 308 |
| 18 | Modifications of dietary flavonoids towards improved bioactivity: An update on structure–activity relationship Lei Chen, Hui Teng, Zhenglu Xie et al. · Critical Reviews in Food Science and Nutrition | 20 Jul 2016 | 293 |
| 19 | Countercurrent Separation of Natural Products: An Update J. Brent Friesen, James B. McAlpine, Shao‐Nong Chen et al. · Journal of Natural Products | 15 Jul 2015 | 293 |
| 20 | Mechanistic insights and perspectives involved in neuroprotective action of quercetin Amarjot Kaur Grewal, Thakur Gurjeet Singh, Deepak Sharma et al. · Biomedicine & Pharmacotherapy | 24 May 2021 | 288 |
| 21 | Covalent EGFR inhibitor analysis reveals importance of reversible interactions to potency and mechanisms of drug resistance Phillip A. Schwartz, Petr Kuzmič, James E. Solowiej et al. · Proceedings of the National Academy of Sciences | 17 Dec 2013 | 284 |
| 22 | Synthetic methodologies of achiral diarylmethanols, diaryl and triarylmethanes (TRAMs) and medicinal properties of diaryl and triarylmethanes-an overview Sankalan Mondal, Gautam Panda · RSC Advances | 2014 | 278 |
| 23 | PF-06463922 is a potent and selective next-generation ROS1/ALK inhibitor capable of blocking crizotinib-resistant ROS1 mutations Helen Y. Zou et al. · Proceedings of the National Academy of Sciences | 2 Mar 2015 | 271 |
| 24 | Facile elaboration of porphyrins via metal-mediated cross-coupling Stephen G. DiMagno, Victor S.‐Y. Lin, Michael J. Therien · The Journal of Organic Chemistry | Oct 1993 | 265 |
| 25 | European Registry on Helicobacter pylori management (Hp-EuReg): patterns and trends in first-line empirical eradication prescription and outcomes of 5 years and 21 533 patients Olga P. Nyssen et al. · Gut | 21 Sep 2020 | 263 |
| 26 | The Chemokine Receptor CCR7 Activates in Dendritic Cells Two Signaling Modules That Independently Regulate Chemotaxis and Migratory Speed Lorena Riol‐Blanco, Noelia Sánchez‐Sánchez, A.L. Torres et al. · The Journal of Immunology | Apr 2005 | 261 |
| 27 | Common mental disorders in Santiago, Chile Ricardo Araya, Graciela Rojas, Rosemarie Fritsch et al. · The British Journal of Psychiatry | Mar 2001 | 260 |
| 28 | Can Invalid Bioactives Undermine Natural Product-Based Drug Discovery? Jonathan Bisson, James B. McAlpine, J. Brent Friesen et al. · Journal of Medicinal Chemistry | 27 Oct 2015 | 251 |
| 29 | The Biphasic Nature of Nitric Oxide Responses in Tumor Biology Lisa A. Ridnour, Douglas D. Thomas, Sonia Donzelli et al. · Antioxidants and Redox Signaling | Jul 2006 | 247 |
| 30 | Copy-Number Disorders Are a Common Cause of Congenital Kidney Malformations Simone Sanna‐Cherchi et al. · The American Journal of Human Genetics | 15 Nov 2012 | 242 |
| 31 | Crystal Structure of Human Squalene Synthase Jayvardhan Pandit, Dennis E. Danley, Gayle K. Schulte et al. · Journal of Biological Chemistry | Sep 2000 | 241 |
| 32 | The relationship between phenolic compounds from diet and microbiota: impact on human health Lorena Valdés, Amable J. Valdés Cuervo, Nuria Salazar et al. · Food & Function | 2015 | 237 |
| 33 | Recent advances in deep-sea natural products Danielle Skropeta, Liangqian Wei · Natural Product Reports | 2014 | 233 |
| 34 | Differential phosphorylation of azidothymidine, dideoxycytidine, and dideoxyinosine in resting and activated peripheral blood mononuclear cells. Wen Gao, T Shirasaka, David G. Johns et al. · Journal of Clinical Investigation | May 1993 | 233 |
| 35 | Guest Molecule-Responsive Functional Calcium Phosphonate Frameworks for Tuned Proton Conductivity Montse Bazaga-García, Rosario M. P. Colodrero, Maria I. Papadaki et al. · Journal of the American Chemical Society | 18 Mar 2014 | 230 |
| 36 | GPCRdb: the G protein‐coupled receptor database – an introduction Christian Munk, Vignir Ísberg, Stefan Mordalski et al. · British Journal of Pharmacology | 8 May 2016 | 218 |
| 37 | Polyamines and their possible mechanisms involved in plant physiological processes and elicitation of secondary metabolites Seyed Hamid Mustafavi, H Naghdi Badi, Agnieszka Sękara et al. · Acta Physiologiae Plantarum | 3 May 2018 | 214 |
| 38 | Two Group A Streptococcal Peptide Pheromones Act through Opposing Rgg Regulators to Control Biofilm Development Jennifer C. Chang, Breah LaSarre, Juan Cristobal Jimenez et al. · PLoS Pathogens | 4 Aug 2011 | 211 |
| 39 | Production of the Neurotoxin BMAA by a Marine Cyanobacterium Sandra Anne Banack, Holly E. Johnson, Ran Cheng et al. · Marine Drugs | 6 Dec 2007 | 189 |
| 40 | International Variations in Harsh Child Discipline Desmond K. Runyan, V. Shankar, Fatma Hassan et al. · PEDIATRICS | 3 Aug 2010 | 184 |
| 41 | Multi-functional analysis ofKlebsiella pneumoniaefimbrial types in adherence and biofilm formation Marı́a Dolores Alcántar-Curiel, Dana Blackburn, Zeus Saldaña‐Ahuactzi et al. · Virulence | 7 Feb 2013 | 184 |
| 42 | An erythromycin analog produced by reprogramming of polyketide synthesis. Stefano Donadio, James B. McAlpine, P Sheldon et al. · Proceedings of the National Academy of Sciences | Aug 1993 | 183 |
| 43 | Safety and efficacy of black cohosh and red clover for the management of vasomotor symptoms STACIE E. GELLER, LEE P. SHULMAN, Richard Bruce van Breemen et al. · Menopause The Journal of The North American Menopause Society | Nov 2009 | 179 |
| 44 | Mesenchymal stem cells expanded in vitro with human serum for the treatment of acute and chronic graft-versus-host disease: results of a phase I/II clinical trial José Antonio Pérez‐Simón, Olga López‐Villar, Enrique José Andreu et al. · Haematologica | 10 Mar 2011 | 177 |
| 45 | The Evolution of Vivipary in Flowering Plants Thomas Elmqvist, Paul Alan Cox · Oikos | Oct 1996 | 177 |
| 46 | Cardiopulmonary Exercise Test: Fundamentals, Applicability and Interpretation Artur Haddad Herdy, Luiz Eduardo Fonteles Ritt, Ricardo Stein et al. · Arquivos Brasileiros de Cardiologia | 2016 | 173 |
| 47 | Psychosine Accumulates in Membrane Microdomains in the Brain of Krabbe Patients, Disrupting the Raft Architecture Adam B. White, Maria Irene Givogri, Aurora Lopez‐Rosas et al. · Journal of Neuroscience | 13 May 2009 | 173 |
| 48 | A Critical Review on the Synthesis of Natural Sodium Alginate Based Composite Materials: An Innovative Biological Polymer for Biomedical Delivery Applications Awais Ahmad, Nabisab Mujawar Mubarak, Fakiha Tul Jannat et al. · Processes | 11 Jan 2021 | 172 |
| 49 | Methods for the stereoselective cis-cyanohydroxylation and -carboxyhydroxylation of olefins Alan P. Kozikowski, Maciej Adamcz · The Journal of Organic Chemistry | Feb 1983 | 171 |
| 50 | Focusing of nitric oxide mediated nitrosation and oxidative nitrosylation as a consequence of reaction with superoxide Michael Graham Espey, Douglas D. Thomas, Katrina M. Miranda et al. · Proceedings of the National Academy of Sciences | 12 Aug 2002 | 170 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.