Science Explorer Back to mapMap
Institution · Medicon Village

Most cited papers from Medicon Village

What are the most cited papers from Medicon Village?

The most cited paper from Medicon Village is "The repertoire of mutational signatures in human cancer" (Ludmil B. Alexandrov et al., 2020), with 3,854 citations. Next come "Pan-cancer analysis of whole genomes" (3,360) and "Dietary Fiber-Induced Improvement in Glucose Metabolism Is Associated with Increased Abundance of Prevotella" (1,810).

Showing 50 of 60 papers. Every paper with more than 130 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 The repertoire of mutational signatures in human cancer Ludmil B. Alexandrov et al. · Nature Open access1,384 authors 5 Feb 2020 3,854
2 Pan-cancer analysis of whole genomes Lauri A. Aaltonen et al. · Nature Open access1,324 authors 5 Feb 2020 3,360
3 Dietary Fiber-Induced Improvement in Glucose Metabolism Is Associated with Increased Abundance of Prevotella Petia Kovatcheva‐Datchary, Anne C. Nilsson, Rozita Akrami et al. · Cell Metabolism Open access 6 Nov 2015 1,810
4 The evolutionary history of 2,658 cancers Moritz Gerstung et al. · Nature Open access1,441 authors 5 Feb 2020 1,149
5 Patterns of somatic structural variation in human cancer genomes Yilong Li et al. · Nature Open access1,411 authors 5 Feb 2020 1,005
6 Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota Taoufiq Harach, Nittaya Marungruang, N. Duthilleul et al. · Scientific Reports Open access 8 Feb 2017 931
7 Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing Michael Bartoschek, Nikolay Oskolkov, Matteo Bocci et al. · Nature Communications Open access 28 Nov 2018 855
8 Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing Isidro Cortés-Ciriano et al. · Nature Genetics Open access1,407 authors 5 Feb 2020 793
9 Therapeutic targeting of hypoxia and hypoxia-inducible factors in cancer Caroline Wigerup, Sven Påhlman, Daniel Bexell · Pharmacology & Therapeutics Open access 30 Apr 2016 710
10 Analyses of non-coding somatic drivers in 2,658 cancer whole genomes Esther Rheinbay et al. · Nature Open access1,621 authors 5 Feb 2020 674
11 Digital twins to personalize medicine Bergþór Björnsson, Carl A K Borrebaeck, Nils Oskar Elander et al. · Genome Medicine Open access 31 Dec 2019 563
12 Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma Martin Lauss, Marco Donia, Katja Harbst et al. · Nature Communications Open access 17 Nov 2017 510
13 Precision diagnostics: moving towards protein biomarker signatures of clinical utility in cancer Carl A.K. Borrebaeck · Nature reviews. Cancer Review 3 Feb 2017 445
14 From genome-wide arrays to tailor-made biomarker readout – Progress towards routine analysis of skin sensitizing chemicals with GARD Andy Forreryd, Kathrin Stephanie Zeller, Tim Lindberg et al. · Toxicology in Vitro Open access 14 Sep 2016 431
15 Genomic basis for RNA alterations in cancer PCAWG Transcriptome Core Group et al. · Nature Open access1,461 authors 5 Feb 2020 425
16 The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain. John D. Sandy, Carl R. Flannery, Peter J. Neame et al. · Journal of Clinical Investigation Open access May 1992 417
17 The landscape of viral associations in human cancers Marc Zapatka et al. · Nature Genetics Open access1,355 authors 5 Feb 2020 412
18 Biomass-based particles for the formulation of Pickering type emulsions in food and topical applications Marilyn Rayner, Diana Marku, Madeleine Eriksson et al. · Colloids and Surfaces A Physicochemical and Engineering Aspects 26 Mar 2014 405
19 Concentrations of perfluoroalkyl substances (PFASs) in human embryonic and fetal organs from first, second, and third trimester pregnancies Linn Salto Mamsen, Richelle Duque Björvang, Dániel Mucs et al. · Environment International Open access 24 Jan 2019 340
20 Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study Johan Staaf et al. · Nature Medicine Open access 30 Sep 2019 326
21 Normalyzer: A Tool for Rapid Evaluation of Normalization Methods for Omics Data Sets Aakash Chawade, Erik Alexandersson, Fredrik Levander · Journal of Proteome Research Open access 28 Apr 2014 296
22 The Sweden Cancerome Analysis Network - Breast (SCAN-B) Initiative: a large-scale multicenter infrastructure towards implementation of breast cancer genomic analyses in the clinical routine Lao H. Saal, Johan Vallon‐Christersson, Jari Häkkinen et al. · Genome Medicine Open access 2 Feb 2015 292
23 Structural insights into the lipid and ligand regulation of serotonin receptors Peiyu Xu, Sijie Huang, Huibing Zhang et al. · Nature 24 Mar 2021 280
24 A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns Wei Jiao et al. · Nature Communications Open access1,385 authors 5 Feb 2020 246
25 Integrative pathway enrichment analysis of multivariate omics data Marta Paczkowska et al. · Nature Communications Open access1,460 authors 5 Feb 2020 243
26 Extracellular‐Matrix‐Reinforced Bioinks for 3D Bioprinting Human Tissue Martina M. De Santis, Hani N. Alsafadi, Sinem Taş et al. · Advanced Materials Open access 9 Dec 2020 241
27 Proteins and antibodies in serum, plasma, and whole blood—size characterization using asymmetrical flow field-flow fractionation (AF4) Mats Leeman, Jaeyeong Choi, Sebastian Hansson et al. · Analytical and Bioanalytical Chemistry Open access 28 May 2018 228
28 An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvironment Xavier Tekpli et al. · Nature Communications Open access 3 Dec 2019 214
29 The Influence of Hormonal Factors on the Risk of Developing Cervical Cancer and Pre-Cancer: Results from the EPIC Cohort Esther Roura et al. · PLoS ONE Open access 25 Jan 2016 213
30 Intestinal Barrier Dysfunction Develops at the Onset of Experimental Autoimmune Encephalomyelitis, and Can Be Induced by Adoptive Transfer of Auto-Reactive T Cells Mehrnaz Nouri, Anders C. A. Bredberg, Björn R. Weström et al. · PLoS ONE Open access 3 Sep 2014 208
31 Storage and digestion stability of encapsulated curcumin in emulsions based on starch granule Pickering stabilization Ali Marefati, Mariannick Bertrand, Malin Sjöö et al. · Food Hydrocolloids 9 Sep 2016 202
32 A comprehensive approach to rehabilitation interventions following breast cancer treatment - a systematic review of systematic reviews Ulrika Möller, Ingela Beck, Lisa Rydén et al. · BMC Cancer ReviewOpen access 20 May 2019 197
33 Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis Joana Carlevaro-Fita et al. · Communications Biology Open access1,462 authors 5 Feb 2020 195
34 Integrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer Qing‐Bai She, Sofia K. Gruvberger-Saal, Matthew S. Maurer et al. · BMC Cancer Open access 2 Aug 2016 195
35 Digitalization driven retail business model innovation: Evaluation of past and avenues for future research trends Rana Mostaghel, Pejvak Oghazi, Vinit Parida et al. · Journal of Business Research Open access 31 Mar 2022 191
36 A dual-action peptide-containing hydrogel targets wound infection and inflammation Manoj Puthia, Marta Butrym, Jitka Petrlová et al. · Science Translational Medicine Open access 2020 180
37 Chemical composition, digestibility and emulsification properties of octenyl succinic esters of various starches Şenay Şimşek, Maribel Ovando‐Martínez, Ali Marefati et al. · Food Research International 16 May 2015 179
38 Vertical wrap-gated nanowire transistors Tomas Bryllert, Lars‐Erik Wernersson, Truls Löwgren et al. · Nanotechnology Open access 19 May 2006 171
39 VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread Xiujuan Li, Narendra Padhan, Elisabet Ohlin Sjöström et al. · Nature Communications Open access 23 Mar 2016 170
40 Prognostic impact of circulating tumor cell apoptosis and clusters in serial blood samples from patients with metastatic breast cancer in a prospective observational cohort Sara Jansson, Pär‐Ola Bendahl, Anna-Maria Larsson et al. · BMC Cancer Open access 8 Jul 2016 169
41 Extensive intra-phylotype diversity in lactobacilli and bifidobacteria from the honeybee gut Kirsten Ellegaard, Daniel Tamarit, Emelie Javelind et al. · BMC Genomics Open access 9 Apr 2015 167
42 PAPD5-mediated 3′ adenylation and subsequent degradation of miR-21 is disrupted in proliferative disease Joost Boele et al. · Proceedings of the National Academy of Sciences Open access 21 Jul 2014 164
43 SYK Is a Critical Regulator of FLT3 in Acute Myeloid Leukemia Alexandre Puissant, Nina Fenouille, Gabriela Alexe et al. · Cancer Cell Open access Feb 2014 158
44 A high frequency of MDSCs in sepsis patients, with the granulocytic subtype dominating in gram-positive cases Helena Janols, Caroline Bergenfelz, Roni Allaoui et al. · Journal of Leukocyte Biology 13 Jun 2014 156
45 Cell-permeable succinate prodrugs bypass mitochondrial complex I deficiency Johannes K. Ehinger, Sarah Piel, Rhonan Ford et al. · Nature Communications Open access 9 Aug 2016 154
46 Systemic Monocytic-MDSCs Are Generated from Monocytes and Correlate with Disease Progression in Breast Cancer Patients Caroline Bergenfelz, Anna-Maria Larsson, Kristoffer von Stedingk et al. · PLoS ONE Open access 20 May 2015 153
47 Caffeine and Caffeic Acid Inhibit Growth and Modify Estrogen Receptor and Insulin-like Growth Factor I Receptor Levels in Human Breast Cancer Ann H. Rosendahl, Claire M. Perks, Li Zeng et al. · Clinical Cancer Research 18 Feb 2015 149
48 First‐in‐human study with intratumoral administration of a CD40 agonistic antibody, ADC‐1013, in advanced solid malignancies Sandra Irenaeus, Dorte Lisbet Nielsen, Peter Ellmark et al. · International Journal of Cancer 21 Jan 2019 146
49 Experimental lupus is aggravated in mouse strains with impaired induction of neutrophil extracellular traps Deborah Kienhöfer, Jonas Hahn, Julia Stoof et al. · JCI Insight Open access 17 May 2017 146
50 Genomic footprints of activated telomere maintenance mechanisms in cancer Lina Sieverling et al. · Nature Communications Open access1,414 authors 5 Feb 2020 143

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.