| 1 |
Biological insights from 108 schizophrenia-associated genetic loci
Stephan Ripke et al. · Nature
Open access297 authors |
Jul 2014 |
8,181 |
| 2 |
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
eQTLGen et al. · Nature Genetics
Open access218 authors |
26 Apr 2018 |
3,347 |
| 3 |
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Vassily Vladimirovich Trubetskoy et al. · Nature
Open access613 authors |
8 Apr 2022 |
2,894 |
| 4 |
Identification of common genetic risk variants for autism spectrum disorder
Jakob Grove et al. · Nature Genetics
Open access |
25 Feb 2019 |
2,721 |
| 5 |
Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder
Ditte Demontis et al. · Nature Genetics
Open access |
23 Nov 2018 |
2,356 |
| 6 |
Analysis of shared heritability in common disorders of the brain
Verneri Anttila et al. · Science
Open access577 authors |
21 Jun 2018 |
2,056 |
| 7 |
Genome-wide association study identifies five new schizophrenia loci
Stephan Ripke et al. · Nature Genetics
Open access196 authors |
18 Sep 2011 |
1,966 |
| 8 |
How mental health care should change as a consequence of the COVID-19 pandemic
Carmen Moreno et al. · The Lancet Psychiatry
Open access |
16 Jul 2020 |
1,919 |
| 9 |
Large recurrent microdeletions associated with schizophrenia
GROUP et al. · Nature
Open access |
30 Jul 2008 |
1,787 |
| 10 |
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
Antonio F. Pardiñas et al. · Nature Genetics
Open access |
25 Feb 2018 |
1,748 |
| 11 |
Common variants conferring risk of schizophrenia
†Genetic Risk and Outcome in Psychosis (GROUP) et al. · Nature
Open access |
Jul 2009 |
1,723 |
| 12 |
Genome-wide association study identifies 30 loci associated with bipolar disorder
Eli A. Stahl et al. · Nature Genetics
Open access277 authors |
May 2019 |
1,654 |
| 13 |
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Niamh Mullins et al. · Nature Genetics
Open access318 authors |
17 May 2021 |
1,635 |
| 14 |
Benzodiazepine receptors in rat brain
Richard F. Squires, Claus Bræstrup · Nature
|
Apr 1977 |
1,453 |
| 15 |
Specific benzodiazepine receptors in rat brain characterized by high-affinity (3H)diazepam binding.
C. Bræstrup, Richard F. Squires · Proceedings of the National Academy of Sciences
Open access |
Sep 1977 |
1,264 |
| 16 |
Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap
Michael J. Gandal et al. · Science
Open access |
9 Feb 2018 |
1,182 |
| 17 |
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
Christian R. Marshall et al. · Nature Genetics
Open access263 authors |
21 Nov 2016 |
1,160 |
| 18 |
Rivermead Behavioural Memory Test
Peter la Cour, Kate Gallagher · Nordisk Psykologi
|
1990 |
1,007 |
| 19 |
A saturated map of common genetic variants associated with human height
Loïc Yengo et al. · Nature
Open access632 authors |
12 Oct 2022 |
934 |
| 20 |
Rare coding variants in ten genes confer substantial risk for schizophrenia
Tarjinder Singh et al. · Nature
Open access111 authors |
8 Apr 2022 |
930 |
| 21 |
Subcortical brain volume differences in participants with attention deficit hyperactivity disorder in children and adults: a cross-sectional mega-analysis
Martine Hoogman et al. · The Lancet Psychiatry
Open access |
16 Feb 2017 |
914 |
| 22 |
Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains
Ditte Demontis et al. · Nature Genetics
Open access |
26 Jan 2023 |
821 |
| 23 |
Treatment‐resistant depression: definition, prevalence, detection, management, and investigational interventions
Roger S. McIntyre et al. · World Psychiatry
Open access |
15 Sep 2023 |
799 |
| 24 |
Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals
Lasse Folkersen et al. · Nature Metabolism
Open access |
16 Oct 2020 |
793 |
| 25 |
Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction
Daniel Fannar Gudbjartsson et al. · Nature Genetics
|
8 Feb 2009 |
771 |
| 26 |
CNVs conferring risk of autism or schizophrenia affect cognition in controls
Hreinn Stefánsson et al. · Nature
Open access |
18 Dec 2013 |
737 |
| 27 |
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
Padhraig Gormley et al. · Nature Genetics
ReviewOpen access107 authors |
20 Jun 2016 |
722 |
| 28 |
International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci
Caroline M. Nievergelt et al. · Nature Communications
ReviewOpen access179 authors |
8 Oct 2019 |
695 |
| 29 |
Measurement of health-related quality of life for people with dementia: development of a new instrument (DEMQOL) and an evaluation of current methodology
Sarah C. Smith, Donna L. Lamping, Sube Banerjee et al. · Health Technology Assessment
Open access |
Mar 2005 |
655 |
| 30 |
Heritability of Schizophrenia and Schizophrenia Spectrum Based on the Nationwide Danish Twin Register
Rikke W. Hilker, Dorte Helenius, Birgitte Fagerlund et al. · Biological Psychiatry
Open access |
Sep 2017 |
647 |
| 31 |
Acceptance and Commitment Therapy (ACT) for Chronic Pain
Laura S. Hughes, Jodi Clark, Janette A. Colclough et al. · Clinical Journal of Pain
|
9 Aug 2016 |
620 |
| 32 |
Exploring Comorbidity Within Mental Disorders Among a Danish National Population
Oleguer Plana‐Ripoll et al. · JAMA Psychiatry
Open access |
16 Jan 2019 |
618 |
| 33 |
Stereotyped activities produced by amphetamine in several animal species and man
Axel A. Randrup, Ib Munkvad · Psychopharmacology
|
1967 |
617 |
| 34 |
Clozapine v . first- and second-generation antipsychotics in treatment-refractory schizophrenia: systematic review and meta-analysis
Dan J. Siskind, Lara McCartney, Romi Goldschlager et al. · The British Journal of Psychiatry
ReviewOpen access |
7 Jul 2016 |
612 |
| 35 |
Mental Health Service Use in the Community and Schools: Results from the Four-Community MECA Study
Philip J. Leaf, Margarita Alegrı́a, Patricia R. Cohen et al. · Journal of the American Academy of Child & Adolescent Psychiatry
Open access |
Jul 1996 |
612 |
| 36 |
A Screening Questionnaire for mother-infant bonding disorders
Ian Brockington, John Oates, Shona George et al. · Archives of Women s Mental Health
|
15 Mar 2001 |
611 |
| 37 |
A randomised multicentre trial of integrated versus standard treatment for patients with a first episode of psychotic illness
Lone Petersen, Pia Jeppesen, Anne Amalie Elgaard Thorup et al. · BMJ
Open access |
2 Sep 2005 |
603 |
| 38 |
SEVERE ANXIETY INDUCED BY FG 7142, A β-CARBOLINE LIGAND FOR BENZODIAZEPINE RECEPTORS
Rainer Dorow, R. Horowski, Gert Paschelke et al. · The Lancet
|
Jul 1983 |
582 |
| 39 |
Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders
iPSYCH-Broad Autism Group et al. · Nature Genetics
Open access |
15 May 2017 |
572 |
| 40 |
Interaction of Convulsive Ligands with Benzodiazepine Receptors
C. Bræstrup, Ralph Schmiechen, Günter Neef et al. · Science
|
11 Jun 1982 |
548 |
| 41 |
The Global Costs of Schizophrenia
Martin Richard John Knapp, Roshni Mangalore, Judit Simon · Schizophrenia Bulletin
|
2004 |
542 |
| 42 |
Association between Mental Disorders and Subsequent Medical Conditions
Natalie C. Momen et al. · New England Journal of Medicine
Open access |
29 Apr 2020 |
493 |
| 43 |
Disruption of the neurexin 1 gene is associated with schizophrenia
Dan Rujescu et al. · Human Molecular Genetics
Open access |
22 Oct 2008 |
490 |
| 44 |
Brain Glutamate Transporter Proteins Form Homomultimers
Øyvind Haugeto, Kyrre Ullensvang, Line M. Levy et al. · Journal of Biological Chemistry
Open access |
Nov 1996 |
488 |
| 45 |
A major role for common genetic variation in anxiety disorders
Kirstin Lee Purves et al. · Molecular Psychiatry
Open access |
20 Nov 2019 |
476 |
| 46 |
Risk of COVID-19 in health-care workers in Denmark: an observational cohort study
Kasper Karmark Iversen et al. · The Lancet Infectious Diseases
Open access |
3 Aug 2020 |
475 |
| 47 |
Genetic correlations of polygenic disease traits: from theory to practice
Wouter van Rheenen, Wouter J. Peyrot, Andrew Joseph Schork et al. · Nature Reviews Genetics
ReviewOpen access |
6 Jun 2019 |
473 |
| 48 |
Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation
Oleksandr Frei, Dominic Holland, Olav Bjerkehagen Smeland et al. · Nature Communications
Open access |
3 Jun 2019 |
470 |
| 49 |
Temporal disease trajectories condensed from population-wide registry data covering 6.2 million patients
Anders Boeck Jensen, Pope Lloyd Moseley, Tudor Ionel Oprea et al. · Nature Communications
Open access |
24 Jun 2014 |
434 |
| 50 |
Mental Health Problems of Children in Foster Care
June Madsen Clausen, John A. Landsverk, William C. Ganger et al. · Journal of Child and Family Studies
|
Sep 1998 |
434 |