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Institution · National Center for Biotechnology

Most cited papers from National Center for Biotechnology

National Center for Biotechnology

What are the most cited papers from National Center for Biotechnology?

The most cited paper from National Center for Biotechnology is "Transposon vectors containing non-antibiotic resistance selection markers for cloning and stable chromosomal insertion of foreign genes in gram-negative bacteria" (Marta Herrero, Vı́ctor de Lorenzo, Kenneth Nigel Timmis, 1990), with 1,620 citations. Next come "Mini-Tn5 transposon derivatives for insertion mutagenesis, promoter probing, and chromosomal insertion of cloned DNA in gram-negative eubacteria" (1,471) and "An evaluation of terminal‐restriction fragment length polymorphism (T‐RFLP) analysis for the study of microbial community structure and dynamics" (858).

Showing 50 of 60 papers. Every paper with more than 86 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Transposon vectors containing non-antibiotic resistance selection markers for cloning and stable chromosomal insertion of foreign genes in gram-negative bacteria Marta Herrero, Vı́ctor de Lorenzo, Kenneth Nigel Timmis · Journal of Bacteriology Open access Nov 1990 1,620
2 Mini-Tn5 transposon derivatives for insertion mutagenesis, promoter probing, and chromosomal insertion of cloned DNA in gram-negative eubacteria Vı́ctor de Lorenzo, Marta Herrero, Ute Jakubzik et al. · Journal of Bacteriology Open access Nov 1990 1,471
3 An evaluation of terminal‐restriction fragment length polymorphism (T‐RFLP) analysis for the study of microbial community structure and dynamics Andrew Mark Osborn, Edward R. B. Moore, Kenneth Nigel Timmis · Environmental Microbiology Feb 2000 858
4 Alcanivorax borkumensis gen. nov., sp. nov., a new, hydrocarbon-degrading and surfactant-producing marine bacterium Michail M. Yakimov, Peter N. Golyshin, Siegmund Lang et al. · International Journal of Systematic Bacteriology Apr 1998 603
5 Environmental Biology of the Marine Roseobacter Lineage Irene Wagner‐Döbler, Hanno Biebl · Annual Review of Microbiology ReviewOpen access 7 Jul 2006 483
6 Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor. Wayne L. Monsky, Dai Fukumura, Takeshi Gohongi et al. · PubMed 15 Aug 1999 370
7 SpsA, a novel pneumococcal surface protein with specific binding to secretory Immunoglobulin A and secretory component Sven Hammerschmidt, Susanne R. Talay, Per Brandtzæg et al. · Molecular Microbiology Open access Sep 1997 336
8 A general system to integratelacZ fusions into the chromosomes of gram-negative eubacteria: regulation of thePm promoter of theTOL plasmid studied with all controlling elements in monocopy Birgit Kessler, Vı́ctor de Lorenzo, K. N. Timmis · Molecular and General Genetics MGG May 1992 324
9 Aptamer-Based Electrochemical Biosensor for Interferon Gamma Detection Ying Liu, Nazgul Tuleouva, Erlan M. Ramanculov et al. · Analytical Chemistry Open access 3 Sep 2010 322
10 Ferroplasma acidiphilum gen. nov., sp. nov., an acidophilic, autotrophic, ferrous-iron-oxidizing, cell-wall-lacking, mesophilic member of the Ferroplasmaceae fam. nov., comprising a distinct lineage of the Archaea. Olga V. Golyshina, T. A. Pivovarova, G. I. Karavaiko et al. · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY May 2000 321
11 Bacteria designed for bioremediation Kenneth Nigel Timmis, Diemar H. Pieper · Trends in biotechnology Review May 1999 315
12 The genetic history of admixture across inner Eurasia Choongwon Jeong et al. · Nature Ecology & Evolution Open access 29 Apr 2019 265
13 FastPCR: An in silico tool for fast primer and probe design and advanced sequence analysis Ruslan N. Kalendar, Bekbolat Khassenov, Yerlan M. Ramankulov et al. · Genomics Open access 12 May 2017 206
14 Discovery of Complex Mixtures of Novel Long‐Chain Quorum Sensing Signals in Free‐Living and Host‐Associated Marine Alphaproteobacteria Irene Wagner‐Döbler, Verena Thiel, Leo Eberl et al. · ChemBioChem 16 Nov 2005 196
15 Internalin B is essential for adhesion and mediates the invasion of Listeria monocytogenes into human endothelial cells Shreemanta K. Parida, Eugen Domann, Manfred Rohde et al. · Molecular Microbiology Open access Apr 1998 190
16 Apoptosis of mouse dendritic cells is triggered by listeriolysin, the major virulence determinant of Listeria monocytogenes Carlos Alberto Zúñiga Guzmán, Eugen Domann, Manfred Ronde et al. · Molecular Microbiology Apr 1996 182
17 Preconditioning of Human Mesenchymal Stem Cells to Enhance Their Regulation of the Immune Response Arman Saparov, Vyacheslav B. Ogay, Talgat S. Nurgozhin et al. · Stem Cells International Open access 2016 181
18 Immunoinformatics Comes of Age Bette Korber, Montiago LaBute, Karina Yusim · PLoS Computational Biology Open access 26 Jun 2006 177
19 Chaotropic solutes cause water stress in Pseudomonas putida John Edward Hallsworth, Sabina Heim, Kenneth Nigel Timmis · Environmental Microbiology 27 Nov 2003 169
20 Identification of the metabolically active members of a bacterial community in a polychlorinated biphenyl‐polluted moorland soil Balbina Nogales, Edward R. B. Moore, Wolf‐Rainer Abraham et al. · Environmental Microbiology Jun 1999 163
21 An upstream XylR‐ and IHF‐induced nucleoprotein complex regulates the sigma 54‐dependent Pu promoter of TOL plasmid. Vı́ctor de Lorenzo, Marta Herrero, M. Metzke et al. · The EMBO Journal Open access May 1991 161
22 Initial binding of Shiga toxin‐producing Escherichia coli to host cells and subsequent induction of actin rearrangements depend on filamentous EspA‐containing surface appendages Frank Ebel, Till Podzadel, Manfred Rohde et al. · Molecular Microbiology Oct 1998 159
23 Pilot plant for bioremediation of mercury-containing industrial wastewater I. Wagner-D�bler · Applied Microbiology and Biotechnology Aug 2003 156
24 Renaturation and purification of bone morphogenetic protein-2 produced as inclusion bodies in high-cell-density cultures of recombinant Escherichia coli Luis E. Vallejo, Maren Brokelmann, Sabine Marten et al. · Journal of Biotechnology Mar 2002 152
25 The PE-PGRS glycine-rich proteins of Mycobacterium tuberculosis : a new family of fibronectin-binding proteins? The GenBank accession number for the sequence reported in this paper is AF071081. Clara Espitia, Juan Pedro Laclette, Mariana Mondragón‐Palomino et al. · Microbiology Dec 1999 148
26 Non-encapsulated strains reveal novel insights in invasion and survival of Streptococcus suis in epithelial cells Laurentiu Benga, Ralph Goethe, Manfred Rohde et al. · Cellular Microbiology 23 Jul 2004 148
27 Development of an Aptamer Beacon for Detection of Interferon-Gamma Nazgul Tuleuova, Caroline N. Jones, Jun Yan et al. · Analytical Chemistry Feb 2010 145
28 Enhanced stability of enzyme organophosphate hydrolase interfaced on the carbon nanotubes Valber A. Pedrosa, Sheetal Paliwal, Shankar Balasubramanian et al. · Colloids and Surfaces B Biointerfaces 22 Jan 2010 140
29 ‘Clay hutches’: a novel interaction between bacteria and clay minerals Lünsdorf, Erb, Abraham et al. · Environmental Microbiology Apr 2000 136
30 Recent advances to enhance the immunomodulatory potential of mesenchymal stem cells Madina Sarsenova, Yevgeniy Kim, Kamila Raziyeva et al. · Frontiers in Immunology Open access 23 Sep 2022 130
31 From Xenobiotic to Antibiotic, Formation of Protoanemonin from 4-Chlorocatechol by Enzymes of the 3-Oxoadipate Pathway Rafael Blasco, Rolf‐Michael Wittich, Mallavarapu Megharaj et al. · Journal of Biological Chemistry Open access Dec 1995 129
32 The NF-κB Repressing Factor Is Involved in Basal Repression and Interleukin (IL)-1-induced Activation of IL-8 Transcription by Binding to a Conserved NF-κB-flanking Sequence Element Mahtab Nourbakhsh, Solveig Kälble, Anneke Dörrie et al. · Journal of Biological Chemistry Open access Feb 2001 129
33 Cell Retention Devices for Suspended-Cell Perfusion Cultures Leda R. Castilho, Ricardo de Andrade Medronho · Advances in biochemical engineering, biotechnology Book chapter 2002 129
34 Carbon source-dependent inhibition of xyl operon expression of the Pseudomonas putida TOL plasmid Andreas Holtel, Silvia Marqués, Isabel Mohler et al. · Journal of Bacteriology Open access Mar 1994 127
35 Ideonella dechloratans gen.nov., sp.nov., a New Bacterium Capable of Growing Anaerobically with Chlorate as an Electron Acceptor Åsa Malmqvist, Thomas Welander, Edward R. B. Moore et al. · Systematic and Applied Microbiology Mar 1994 127
36 A second update on mapping the human genetic architecture of COVID-19 The COVID-19 Host Genetics Initiative et al. · Nature Open access3,885 authors 6 Sep 2023 125
37 Domain structure and conserved epitopes of Sfb protein, the fibronectin‐binding adhesin of Streptococcus pyogenes Susanne R. Talay, Peter Valentin‐Weigand, Kenneth Nigel Timmis et al. · Molecular Microbiology Aug 1994 124
38 Co-operative binding of human fibronectin to SfbI protein triggers streptococcal invasion into respiratory epithelial cells Susanne R. Talay, Angela Zock, Manfred Rohde et al. · Cellular Microbiology Open access Dec 2000 120
39 Oral delivery of DNA vaccines using attenuatedSalmonella typhimuriumas carrier Ayub Darji, Susanne zur Lage, Annette I. Garbe et al. · FEMS Immunology & Medical Microbiology Open access Apr 2000 119
40 Size-specific mortality of lake bacterioplankton by natural virus communities Markus G. Weinbauer, MG Höfle · Aquatic Microbial Ecology Open access 1998 118
41 Mesenchymal Stem Cell-Based Therapy for Rheumatoid Arthritis Madina Sarsenova, Assel Issabekova, Saule Abisheva et al. · International Journal of Molecular Sciences Open access 27 Oct 2021 116
42 A fibrinogen receptor from group B Streptococcus interacts with fibrinogen by repetitive units with novel ligand binding sites Axel Schubert, Katherina Zakikhany, Mark E. Schreiner et al. · Molecular Microbiology Open access Oct 2002 116
43 Protective Immune Response againstStreptococcus pyogenesin Mice after Intranasal Vaccination with the Fibronectin‐Binding Protein SfbI Carlos Alberto Zúñiga Guzmán, Susanne R. Talay, Gabriella Molinari et al. · The Journal of Infectious Diseases Open access Apr 1999 115
44 Constitutive silencing of IFN‐β promoter is mediated by NRF (NF‐κB‐repressing factor), a nuclear inhibitor of NF‐κB Mahtab Nourbakhsh, H. Häuser · The EMBO Journal Open access 15 Nov 1999 114
45 Purification and crystallization of 2,3-dihydroxybiphenyl 1,2-dioxygenase. Lindsay D. Eltis, Bettina Hofmann, Hans Jürgen Hecht et al. · Journal of Biological Chemistry Open access Feb 1993 108
46 A gastrolith protein serving a dual role in the formation of an amorphous mineral containing extracellular matrix Assaf Shechter, Lilah Glazer, Shira Cheled et al. · Proceedings of the National Academy of Sciences Open access 14 May 2008 106
47 DNA sequence determination of the TOL plasmid (pWW0) xylGFJ genes of Pseudomonas putida: implications for the evolution of aromatic catabolism J. Horn, Shigeaki Harayama, Kenneth Nigel Timmis · Molecular Microbiology Oct 1991 103
48 Hydrogen Peroxide-Mediated Killing ofCaenorhabditis elegansbyStreptococcus pyogenes Wim Jansen, Maike Bolm, Rudi Balling et al. · Infection and Immunity Open access Sep 2002 99
49 A microdevice for multiplexed detection of T-cell-secreted cytokines He Zhu, Gulnaz Stybayeva, Mónica Macal et al. · Lab on a Chip 2008 97
50 Larger H 0 values in the CMB dipole direction Orlando Luongo, Marco Muccino, Eoin Ó Colgáin et al. · Physical review. D/Physical review. D. Open access 10 May 2022 96

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.