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Most cited papers from NIHR Imperial Biomedical Research Centre

What are the most cited papers from NIHR Imperial Biomedical Research Centre?

The most cited paper from NIHR Imperial Biomedical Research Centre is "Analysis of protein-coding genetic variation in 60,706 humans" (Monkol Lek et al., 2016), with 10,439 citations. Next come "Open for innovation: the role of openness in explaining innovation performance among U.K. manufacturing firms" (6,313) and "Machine learning for molecular and materials science" (5,033).

Showing 50 of 59 papers. Every paper with more than 726 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Analysis of protein-coding genetic variation in 60,706 humans Monkol Lek et al. · Nature Open access Aug 2016 10,439
2 Open for innovation: the role of openness in explaining innovation performance among U.K. manufacturing firms Keld Laursen, Ammon J. Salter · Strategic Management Journal Open access 21 Nov 2005 6,313
3 Machine learning for molecular and materials science Keith T. Butler, Daniel W. Davies, Hugh Cartwright et al. · Nature Open access Jul 2018 5,033
4 Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK Merryn Voysey et al. · The Lancet Open access765 authors 8 Dec 2020 5,030
5 Allergic Rhinitis and its Impact on Asthma (ARIA) 2008* Jean Bousquet et al. · Allergy Open access 7 Mar 2008 4,764
6 A Flexible Growth Function for Empirical Use F. J. RICHARDS · Journal of Experimental Botany 1959 4,234
7 Estimating the effects of non-pharmaceutical interventions on COVID-19 in Europe Seth Flaxman et al. · Nature Open access 8 Jun 2020 3,852
8 Architecture of the Photosynthetic Oxygen-Evolving Center Kristina N. Ferreira, T.M. Iverson, Karim Maghlaoui et al. · Science 9 Feb 2004 3,351
9 International evaluation of an AI system for breast cancer screening Scott Mayer McKinney et al. · Nature Open access 2020 3,314
10 Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial Pedro M. Folegatti et al. · The Lancet Open access365 authors 20 Jul 2020 2,629
11 Single-junction organic solar cells with over 19% efficiency enabled by a refined double-fibril network morphology Lei Zhu, Ming Zhang, Jinqiu Xu et al. · Nature Materials Open access 5 May 2022 2,439
12 Current status of cadmium as an environmental health problem Lars Järup, Agneta Åkesson · Toxicology and Applied Pharmacology 5 May 2009 2,370
13 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk Georg Ehret et al. · Nature Open access346 authors 9 Sep 2011 2,085
14 Attention gated networks: Learning to leverage salient regions in medical images Jo Schlemper, Ozan Oktay, Michiel Schaap et al. · Medical Image Analysis Open access 5 Feb 2019 2,016
15 Global impact of the first year of COVID-19 vaccination: a mathematical modelling study Oliver John Watson, Gregory Barnsley, Jaspreet Toor et al. · The Lancet Infectious Diseases Open access 23 Jun 2022 1,889
16 Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvedilol Or Metoprolol European Trial (COMET): randomised controlled trial Philip Alexander Poole-Wilson, Karl B Swedberg, John G.F. Cleland et al. · The Lancet Open access Jul 2003 1,877
17 Neuroinflammation in Alzheimer's disease: Current evidence and future directions Valeria Calsolaro, Paul Edison · Alzheimer s & Dementia 11 May 2016 1,797
18 Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes Rainer Malik et al. · Nature Genetics Open access428 authors 12 Mar 2018 1,753
19 Long covid—mechanisms, risk factors, and management Harry Crook, Sanara Raza, Joseph Nowell et al. · BMJ 26 Jul 2021 1,747
20 Advances in Quantum Cryptography Stefano Pirandola, Ulrik L. Andersen, Leonardo Banchi et al. · White Rose Research Online (University of Leeds, The University of Sheffield, University of York) Open access Jun 2019 1,584
21 Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits the Million Veteran Program et al. · Nature Genetics Open access281 authors 17 Sep 2018 1,523
22 SOLAR INFLUENCES ON CLIMATE Lesley J. Gray, J. Beer, Marvin A. Geller et al. · Reviews of Geophysics Open access 29 Oct 2010 1,406
23 Structure and Mechanism of the Lactose Permease of Escherichia coli Jeff Abramson, Irina Nikolaevna Smirnova, Vladimir N. Kasho et al. · Science 31 Jul 2003 1,400
24 Effectiveness of the Pfizer-BioNTech and Oxford-AstraZeneca vaccines on covid-19 related symptoms, hospital admissions, and mortality in older adults in England: test negative case-control study Jamie Lopez Bernal, Nick J Andrews, Charlotte Gower et al. · BMJ Open access 13 May 2021 1,398
25 The global burden of viral hepatitis from 1990 to 2013: findings from the Global Burden of Disease Study 2013 Jeffrey D Stanaway et al. · The Lancet Open access 7 Jul 2016 1,388
26 The Emergence of Circular Economy: A New Framing Around Prolonging Resource Productivity Fenna Blomsma, Geraldine Brennan · Journal of Industrial Ecology Open access 9 May 2017 1,362
27 Comparative analysis of the risks of hospitalisation and death associated with SARS-CoV-2 omicron (B.1.1.529) and delta (B.1.617.2) variants in England: a cohort study Tommy Nyberg et al. · The Lancet Open access 16 Mar 2022 1,307
28 Reporting guidelines for clinical trial reports for interventions involving artificial intelligence: the CONSORT-AI extension Xiaoxuan Liu et al. · Nature Medicine Open access Sep 2020 1,301
29 European Resuscitation Council Guidelines for Resuscitation 2015 Gavin D. Perkins et al. · Resuscitation Oct 2015 1,300
30 Correlates of protection against symptomatic and asymptomatic SARS-CoV-2 infection Shuo Feng et al. · Nature Medicine Open access 29 Sep 2021 1,247
31 Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials Merryn Voysey et al. · The Lancet Open access766 authors 21 Feb 2021 1,213
32 Senescence and the SASP: many therapeutic avenues Jodie Birch, Jesús Gil · Genes & Development Open access Dec 2020 1,186
33 DAGAN: Deep De-Aliasing Generative Adversarial Networks for Fast Compressed Sensing MRI Reconstruction Guang Zhong Yang, Simiao Yu, Hao Dong et al. · IEEE Transactions on Medical Imaging Open access 21 Dec 2017 1,128
34 SARS-CoV-2 evolution during treatment of chronic infection Steven A. Kemp et al. · Nature Open access1,134 authors 5 Feb 2021 1,091
35 Suppression of a SARS-CoV-2 outbreak in the Italian municipality of Vo’ Enrico Lavezzo et al. · Nature Open access 30 Jun 2020 1,035
36 Colloidal nanoparticles as advanced biological sensors Philip D. Howes, Rona Chandrawati, Molly M. Stevens · Science 2 Oct 2014 1,028
37 Lipoprotein(a), PCSK9 Inhibition, and Cardiovascular Risk Michelle L. O’Donoghue, Sergio Fazio, Robert Patrick Giugliano et al. · Circulation Open access 17 Jan 2019 997
38 A review of reverse osmosis membrane fouling and control strategies Shanxue Jiang, Yuening Li, Bradley P. Ladewig · The Science of The Total Environment Open access 8 Apr 2017 988
39 Epidemiological determinants of spread of causal agent of severe acute respiratory syndrome in Hong Kong Christl Ann Donnelly, Azra C. Ghani, GM Leung et al. · The Lancet Open access May 2003 985
40 Polarity-Sensitive Modulation of Cortical Neurotransmitters by Transcranial Stimulation Charlotte Jane Stagg, Jonathan G. Best, Mary C. Stephenson et al. · Journal of Neuroscience Open access 22 Apr 2009 965
41 Diagnostic accuracy of deep learning in medical imaging: a systematic review and meta-analysis Ravi Aggarwal, Viknesh Sounderajah, Guy Martin et al. · npj Digital Medicine ReviewOpen access 7 Apr 2021 952
42 Future challenges for clinical care of an ageing population infected with HIV: a modelling study Mikaëla Smit, Kees Brinkman, Suzanne E. Geerlings et al. · The Lancet Infectious Diseases Open access 12 Jun 2015 947
43 A catalog of genetic loci associated with kidney function from analyses of a million individuals Lifelines Cohort Study et al. · Nature Genetics Open access329 authors 31 May 2019 946
44 Architecture of Succinate Dehydrogenase and Reactive Oxygen Species Generation Victoria L. Yankovskaya, Rob Horsefield, Susanna Törnroth‐Horsefield et al. · Science 30 Jan 2003 927
45 Some Uses of Happiness Data in Economics Rafael Di Tella, Robert MacCulloch · The Journal of Economic Perspectives Open access Feb 2006 908
46 Recent Advances in the Development of Semiconducting DPP‐Containing Polymers for Transistor Applications Christian B. O. Nielsen, Mathieu G. R. Turbiez, Iain A. McCulloch · Advanced Materials 25 Sep 2012 880
47 Community transmission and viral load kinetics of the SARS-CoV-2 delta (B.1.617.2) variant in vaccinated and unvaccinated individuals in the UK: a prospective, longitudinal, cohort study Anika Singanayagam et al. · The Lancet Infectious Diseases Open access 29 Oct 2021 830
48 Controlling Shear Stress in 3D Bioprinting is a Key Factor to Balance Printing Resolution and Stem Cell Integrity Andreas Blaeser, Daniela F. Duarte Campos, Uta Puster et al. · Advanced Healthcare Materials 2 Dec 2015 826
49 Synthetic polymer scaffolds for tissue engineering Elsie Place, Julian H. George, Charlotte K. Williams et al. · Chemical Society Reviews Review 2009 816
50 Automated cardiovascular magnetic resonance image analysis with fully convolutional networks Wenjia Bai et al. · Journal of Cardiovascular Magnetic Resonance Open access Feb 2018 802

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.