| 1 |
Analysis of protein-coding genetic variation in 60,706 humans
Monkol Lek et al. · Nature
Open access |
Aug 2016 |
10,439 |
| 2 |
Open for innovation: the role of openness in explaining innovation performance among U.K. manufacturing firms
Keld Laursen, Ammon J. Salter · Strategic Management Journal
Open access |
21 Nov 2005 |
6,313 |
| 3 |
Machine learning for molecular and materials science
Keith T. Butler, Daniel W. Davies, Hugh Cartwright et al. · Nature
Open access |
Jul 2018 |
5,033 |
| 4 |
Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK
Merryn Voysey et al. · The Lancet
Open access765 authors |
8 Dec 2020 |
5,030 |
| 5 |
Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*
Jean Bousquet et al. · Allergy
Open access |
7 Mar 2008 |
4,764 |
| 6 |
A Flexible Growth Function for Empirical Use
F. J. RICHARDS · Journal of Experimental Botany
|
1959 |
4,234 |
| 7 |
Estimating the effects of non-pharmaceutical interventions on COVID-19 in Europe
Seth Flaxman et al. · Nature
Open access |
8 Jun 2020 |
3,852 |
| 8 |
Architecture of the Photosynthetic Oxygen-Evolving Center
Kristina N. Ferreira, T.M. Iverson, Karim Maghlaoui et al. · Science
|
9 Feb 2004 |
3,351 |
| 9 |
International evaluation of an AI system for breast cancer screening
Scott Mayer McKinney et al. · Nature
Open access |
2020 |
3,314 |
| 10 |
Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial
Pedro M. Folegatti et al. · The Lancet
Open access365 authors |
20 Jul 2020 |
2,629 |
| 11 |
Single-junction organic solar cells with over 19% efficiency enabled by a refined double-fibril network morphology
Lei Zhu, Ming Zhang, Jinqiu Xu et al. · Nature Materials
Open access |
5 May 2022 |
2,439 |
| 12 |
Current status of cadmium as an environmental health problem
Lars Järup, Agneta Åkesson · Toxicology and Applied Pharmacology
|
5 May 2009 |
2,370 |
| 13 |
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
Georg Ehret et al. · Nature
Open access346 authors |
9 Sep 2011 |
2,085 |
| 14 |
Attention gated networks: Learning to leverage salient regions in medical images
Jo Schlemper, Ozan Oktay, Michiel Schaap et al. · Medical Image Analysis
Open access |
5 Feb 2019 |
2,016 |
| 15 |
Global impact of the first year of COVID-19 vaccination: a mathematical modelling study
Oliver John Watson, Gregory Barnsley, Jaspreet Toor et al. · The Lancet Infectious Diseases
Open access |
23 Jun 2022 |
1,889 |
| 16 |
Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvedilol Or Metoprolol European Trial (COMET): randomised controlled trial
Philip Alexander Poole-Wilson, Karl B Swedberg, John G.F. Cleland et al. · The Lancet
Open access |
Jul 2003 |
1,877 |
| 17 |
Neuroinflammation in Alzheimer's disease: Current evidence and future directions
Valeria Calsolaro, Paul Edison · Alzheimer s & Dementia
|
11 May 2016 |
1,797 |
| 18 |
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
Rainer Malik et al. · Nature Genetics
Open access428 authors |
12 Mar 2018 |
1,753 |
| 19 |
Long covid—mechanisms, risk factors, and management
Harry Crook, Sanara Raza, Joseph Nowell et al. · BMJ
|
26 Jul 2021 |
1,747 |
| 20 |
Advances in Quantum Cryptography
Stefano Pirandola, Ulrik L. Andersen, Leonardo Banchi et al. · White Rose Research Online (University of Leeds, The University of Sheffield, University of York)
Open access |
Jun 2019 |
1,584 |
| 21 |
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
the Million Veteran Program et al. · Nature Genetics
Open access281 authors |
17 Sep 2018 |
1,523 |
| 22 |
SOLAR INFLUENCES ON CLIMATE
Lesley J. Gray, J. Beer, Marvin A. Geller et al. · Reviews of Geophysics
Open access |
29 Oct 2010 |
1,406 |
| 23 |
Structure and Mechanism of the Lactose Permease of Escherichia coli
Jeff Abramson, Irina Nikolaevna Smirnova, Vladimir N. Kasho et al. · Science
|
31 Jul 2003 |
1,400 |
| 24 |
Effectiveness of the Pfizer-BioNTech and Oxford-AstraZeneca vaccines on covid-19 related symptoms, hospital admissions, and mortality in older adults in England: test negative case-control study
Jamie Lopez Bernal, Nick J Andrews, Charlotte Gower et al. · BMJ
Open access |
13 May 2021 |
1,398 |
| 25 |
The global burden of viral hepatitis from 1990 to 2013: findings from the Global Burden of Disease Study 2013
Jeffrey D Stanaway et al. · The Lancet
Open access |
7 Jul 2016 |
1,388 |
| 26 |
The Emergence of Circular Economy: A New Framing Around Prolonging Resource Productivity
Fenna Blomsma, Geraldine Brennan · Journal of Industrial Ecology
Open access |
9 May 2017 |
1,362 |
| 27 |
Comparative analysis of the risks of hospitalisation and death associated with SARS-CoV-2 omicron (B.1.1.529) and delta (B.1.617.2) variants in England: a cohort study
Tommy Nyberg et al. · The Lancet
Open access |
16 Mar 2022 |
1,307 |
| 28 |
Reporting guidelines for clinical trial reports for interventions involving artificial intelligence: the CONSORT-AI extension
Xiaoxuan Liu et al. · Nature Medicine
Open access |
Sep 2020 |
1,301 |
| 29 |
European Resuscitation Council Guidelines for Resuscitation 2015
Gavin D. Perkins et al. · Resuscitation
|
Oct 2015 |
1,300 |
| 30 |
Correlates of protection against symptomatic and asymptomatic SARS-CoV-2 infection
Shuo Feng et al. · Nature Medicine
Open access |
29 Sep 2021 |
1,247 |
| 31 |
Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials
Merryn Voysey et al. · The Lancet
Open access766 authors |
21 Feb 2021 |
1,213 |
| 32 |
Senescence and the SASP: many therapeutic avenues
Jodie Birch, Jesús Gil · Genes & Development
Open access |
Dec 2020 |
1,186 |
| 33 |
DAGAN: Deep De-Aliasing Generative Adversarial Networks for Fast Compressed Sensing MRI Reconstruction
Guang Zhong Yang, Simiao Yu, Hao Dong et al. · IEEE Transactions on Medical Imaging
Open access |
21 Dec 2017 |
1,128 |
| 34 |
SARS-CoV-2 evolution during treatment of chronic infection
Steven A. Kemp et al. · Nature
Open access1,134 authors |
5 Feb 2021 |
1,091 |
| 35 |
Suppression of a SARS-CoV-2 outbreak in the Italian municipality of Vo’
Enrico Lavezzo et al. · Nature
Open access |
30 Jun 2020 |
1,035 |
| 36 |
Colloidal nanoparticles as advanced biological sensors
Philip D. Howes, Rona Chandrawati, Molly M. Stevens · Science
|
2 Oct 2014 |
1,028 |
| 37 |
Lipoprotein(a), PCSK9 Inhibition, and Cardiovascular Risk
Michelle L. O’Donoghue, Sergio Fazio, Robert Patrick Giugliano et al. · Circulation
Open access |
17 Jan 2019 |
997 |
| 38 |
A review of reverse osmosis membrane fouling and control strategies
Shanxue Jiang, Yuening Li, Bradley P. Ladewig · The Science of The Total Environment
Open access |
8 Apr 2017 |
988 |
| 39 |
Epidemiological determinants of spread of causal agent of severe acute respiratory syndrome in Hong Kong
Christl Ann Donnelly, Azra C. Ghani, GM Leung et al. · The Lancet
Open access |
May 2003 |
985 |
| 40 |
Polarity-Sensitive Modulation of Cortical Neurotransmitters by Transcranial Stimulation
Charlotte Jane Stagg, Jonathan G. Best, Mary C. Stephenson et al. · Journal of Neuroscience
Open access |
22 Apr 2009 |
965 |
| 41 |
Diagnostic accuracy of deep learning in medical imaging: a systematic review and meta-analysis
Ravi Aggarwal, Viknesh Sounderajah, Guy Martin et al. · npj Digital Medicine
ReviewOpen access |
7 Apr 2021 |
952 |
| 42 |
Future challenges for clinical care of an ageing population infected with HIV: a modelling study
Mikaëla Smit, Kees Brinkman, Suzanne E. Geerlings et al. · The Lancet Infectious Diseases
Open access |
12 Jun 2015 |
947 |
| 43 |
A catalog of genetic loci associated with kidney function from analyses of a million individuals
Lifelines Cohort Study et al. · Nature Genetics
Open access329 authors |
31 May 2019 |
946 |
| 44 |
Architecture of Succinate Dehydrogenase and Reactive Oxygen Species Generation
Victoria L. Yankovskaya, Rob Horsefield, Susanna Törnroth‐Horsefield et al. · Science
|
30 Jan 2003 |
927 |
| 45 |
Some Uses of Happiness Data in Economics
Rafael Di Tella, Robert MacCulloch · The Journal of Economic Perspectives
Open access |
Feb 2006 |
908 |
| 46 |
Recent Advances in the Development of Semiconducting DPP‐Containing Polymers for Transistor Applications
Christian B. O. Nielsen, Mathieu G. R. Turbiez, Iain A. McCulloch · Advanced Materials
|
25 Sep 2012 |
880 |
| 47 |
Community transmission and viral load kinetics of the SARS-CoV-2 delta (B.1.617.2) variant in vaccinated and unvaccinated individuals in the UK: a prospective, longitudinal, cohort study
Anika Singanayagam et al. · The Lancet Infectious Diseases
Open access |
29 Oct 2021 |
830 |
| 48 |
Controlling Shear Stress in 3D Bioprinting is a Key Factor to Balance Printing Resolution and Stem Cell Integrity
Andreas Blaeser, Daniela F. Duarte Campos, Uta Puster et al. · Advanced Healthcare Materials
|
2 Dec 2015 |
826 |
| 49 |
Synthetic polymer scaffolds for tissue engineering
Elsie Place, Julian H. George, Charlotte K. Williams et al. · Chemical Society Reviews
Review |
2009 |
816 |
| 50 |
Automated cardiovascular magnetic resonance image analysis with fully convolutional networks
Wenjia Bai et al. · Journal of Cardiovascular Magnetic Resonance
Open access |
Feb 2018 |
802 |