| 1 |
Effect of Abaloparatide vs Placebo on New Vertebral Fractures in Postmenopausal Women With Osteoporosis
Paul D. Miller, Gary Hattersley, Bente Juel Riis et al. · JAMA
Open access |
16 Aug 2016 |
869 |
| 2 |
Call for standardized definitions of osteoarthritis and risk stratification for clinical trials and clinical use
Virginia B. Kraus, Francisco Javier Blanco, Martin Englund et al. · Osteoarthritis and Cartilage
Open access |
11 Apr 2015 |
668 |
| 3 |
Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture
Hou‐Feng Zheng et al. · Nature
Open access155 authors |
14 Sep 2015 |
639 |
| 4 |
Multiple Genetic Loci for Bone Mineral Density and Fractures
Unnur Styrkársdóttir, Bjarni V. Halldórsson, Sólveig Grétarsdóttir et al. · New England Journal of Medicine
Open access |
29 Apr 2008 |
634 |
| 5 |
Comparison of the Effect of Denosumab and Alendronate on BMD and Biochemical Markers of Bone Turnover in Postmenopausal Women With Low Bone Mass: A Randomized, Blinded, Phase 3 Trial
Jacques P. Brown, Richard Lewis Prince, Chad L. Deal et al. · Journal of Bone and Mineral Research
|
16 Dec 2008 |
609 |
| 6 |
The good and the bad collagens of fibrosis – Their role in signaling and organ function
M.A. Karsdal, Signe Holm Nielsen, Diana Julie Leeming et al. · Advanced Drug Delivery Reviews
Review |
20 Jul 2017 |
514 |
| 7 |
Collagens and Cancer associated fibroblasts in the reactive stroma and its relation to Cancer biology
Neel Ingemann Nissen, M.A. Karsdal, Nicholas Willumsen · Journal of Experimental & Clinical Cancer Research
Open access |
6 Mar 2019 |
507 |
| 8 |
The Type I Collagen Fragments ICTP and CTX Reveal Distinct Enzymatic Pathways of Bone Collagen Degradation
Patrick Garnero, Mercedes Ferreras, M.A. Karsdal et al. · Journal of Bone and Mineral Research
Open access |
May 2003 |
477 |
| 9 |
Uncoupling of type II collagen synthesis and degradation predicts progression of joint damage in patients with knee osteoarthritis
Patrick Garnero, Xavier Ayral, Jean‐Charles Rousseau et al. · Arthritis & Rheumatism
|
Oct 2002 |
400 |
| 10 |
Disease-modifying treatments for osteoarthritis (DMOADs) of the knee and hip: lessons learned from failures and opportunities for the future
M.A. Karsdal, Martin Michaelis, Christoph H. Ladel et al. · Osteoarthritis and Cartilage
Open access |
3 Aug 2016 |
393 |
| 11 |
New sequence variants associated with bone mineral density
Unnur Styrkársdóttir, Bjarni V. Halldórsson, Sólveig Grétarsdóttir et al. · Nature Genetics
|
14 Dec 2008 |
365 |
| 12 |
Effect of Intra-Articular Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With Osteoarthritis
Marc C. Hochberg, Ali Guermazi, Hans Guehring et al. · JAMA
Open access |
8 Oct 2019 |
353 |
| 13 |
Evidence that epithelial glycoprotein 330/megalin mediates uptake of polybasic drugs.
Søren K. Moestrup, Shumao Cui, Henrik Vorum et al. · Journal of Clinical Investigation
Open access |
Sep 1995 |
344 |
| 14 |
The extracellular matrix in the kidney: a source of novel non-invasive biomarkers of kidney fibrosis?
Federica Genovese, Alba A Manresa, Diana Julie Leeming et al. · Fibrogenesis & Tissue Repair
Open access |
28 Mar 2014 |
342 |
| 15 |
Matrix metalloproteinases (MMP) and cathepsin K contribute differently to osteoclastic activities
Jean‐Marie Delaissé, Thomas Levin Andersen, Michael T. Engsig et al. · Microscopy Research and Technique
|
18 Jul 2003 |
341 |
| 16 |
Role of Gastrointestinal Hormones in Postprandial Reduction of Bone Resorption
Dennis Bang Henriksen, Peter Alexandersen, Nina H. Bjarnason et al. · Journal of Bone and Mineral Research
Open access |
Dec 2003 |
333 |
| 17 |
Value of biomarkers in osteoarthritis: current status and perspectives
Martin Lotz et al. · Annals of the Rheumatic Diseases
Open access |
30 Jul 2013 |
328 |
| 18 |
Longitudinal change in collagen degradation biomarkers in idiopathic pulmonary fibrosis: an analysis from the prospective, multicentre PROFILE study
Gisli R. Jenkins, Juliet K. Simpson, Gauri Saini et al. · The Lancet Respiratory Medicine
Open access |
12 Mar 2015 |
326 |
| 19 |
Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density
Guðmar Þorleifsson et al. · Nature Genetics
Open access |
28 Jun 2009 |
324 |
| 20 |
The future of blood‐based biomarkers for Alzheimer's disease
Kim Henriksen, Sid E. O’Bryant, Harald Juergen Hampel et al. · Alzheimer s & Dementia
Open access |
11 Jul 2013 |
320 |
| 21 |
Blood‐based biomarkers in Alzheimer disease: Current state of the science and a novel collaborative paradigm for advancing from discovery to clinic
Sid E. O’Bryant et al. · Alzheimer s & Dementia
Open access |
18 Nov 2016 |
317 |
| 22 |
Guidelines for the standardization of preanalytic variables for blood‐based biomarker studies in Alzheimer's disease research
Sid E. O’Bryant et al. · Alzheimer s & Dementia
Open access |
30 Sep 2014 |
293 |
| 23 |
Extracellular Matrix Remodeling: The Common Denominator in Connective Tissue Diseases Possibilities for Evaluation and Current Understanding of the Matrix as More Than a Passive Architecture, but a Key Player in Tissue Failure
M.A. Karsdal, Mette Juul Nielsen, Jannie Marie Bülow Sand et al. · Assay and Drug Development Technologies
Open access |
9 Oct 2012 |
285 |
| 24 |
Local communication on and within bone controls bone remodeling
Kim Henriksen, Anita Vibsig Neutzsky-Wulff, Lynda Faye Bonewald et al. · Bone
|
6 Apr 2009 |
281 |
| 25 |
Novel insights into the function and dynamics of extracellular matrix in liver fibrosis
M.A. Karsdal, Tina Manon‐Jensen, Federica Genovese et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology
Open access |
12 Mar 2015 |
271 |
| 26 |
ADAPT: An Algorithm Incorporating PRO‐C3 Accurately Identifies Patients With NAFLD and Advanced Fibrosis
Samuel Joseph Daniels, Diana Julie Leeming, Mohammed Eslam et al. · Hepatology
Open access |
16 Jul 2018 |
268 |
| 27 |
The minor collagens in articular cartilage
Yunyun Luo, Dovilė Sinkevičiūtė, Yi He et al. · Protein & Cell
Open access |
17 Feb 2017 |
268 |
| 28 |
Recommendations for enterovirus diagnostics and characterisation within and beyond Europe
Heli Harvala et al. · Journal of Clinical Virology
Open access |
6 Feb 2018 |
266 |
| 29 |
Ovariectomized rats as a model of postmenopausal osteoarthritis: validation and application
Pernille Høegh-Andersen, László B. Tankó, Thomas Levin Andersen et al. · Arthritis Research & Therapy
Open access |
19 Feb 2004 |
265 |
| 30 |
An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD)
Michèle Vacca et al. · Nature Metabolism
Open access238 authors |
12 Jun 2024 |
260 |
| 31 |
A novel assay for extracellular matrix remodeling associated with liver fibrosis: An enzyme-linked immunosorbent assay (ELISA) for a MMP-9 proteolytically revealed neo-epitope of type III collagen
Natasha Barascuk, Sanne Skovgård Veidal, Lise Larsen et al. · Clinical Biochemistry
|
12 Apr 2010 |
260 |
| 32 |
A new marker for osteoarthritis: Cross‐sectional and longitudinal approach
Max Reijman, Johanna M W Hazes, S. Bierma-Zeinstra et al. · Arthritis & Rheumatism
|
Aug 2004 |
257 |
| 33 |
Matrix Metalloproteinase-dependent Activation of Latent Transforming Growth Factor-β Controls the Conversion of Osteoblasts into Osteocytes by Blocking Osteoblast Apoptosis
M.A. Karsdal, Lykke Larsen, Michael T. Engsig et al. · Journal of Biological Chemistry
Open access |
Nov 2002 |
247 |
| 34 |
Are Nonresorbing Osteoclasts Sources of Bone Anabolic Activity?
M.A. Karsdal, Thomas John Martin, Jens Bollerslev et al. · Journal of Bone and Mineral Research
Open access |
16 Jan 2007 |
244 |
| 35 |
Collagen‐mediated hemostasis
Tina Manon‐Jensen, N.G. Kjeld, M.A. Karsdal · Journal of Thrombosis and Haemostasis
Open access |
10 Jan 2016 |
237 |
| 36 |
Osteoarthritis phenotypes and novel therapeutic targets
W.E. van Spil, Olga Kubassova, Mikael Boesen et al. · Biochemical Pharmacology
Open access |
Mar 2019 |
234 |
| 37 |
The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis
Hannah V. Woodcock et al. · Nature Communications
Open access |
27 Dec 2018 |
233 |
| 38 |
Osteoclast Activity and Subtypes as a Function of Physiology and Pathology—Implications for Future Treatments of Osteoporosis
Kim Henriksen, Jens Bollerslev, Vincent E. Everts et al. · Endocrine Reviews
Open access |
Feb 2011 |
229 |
| 39 |
Recent advances in understanding the phenotypes of osteoarthritis
Ali Mobasheri, Simo S. Saarakkala, Mikko Finnilä et al. · F1000Research
Open access |
12 Dec 2019 |
223 |
| 40 |
Genome-wide association study identifies sequence variants on 6q21 associated with age at menarche
Patrick Sulem et al. · Nature Genetics
|
17 May 2009 |
222 |
| 41 |
Should subchondral bone turnover be targeted when treating osteoarthritis?
M.A. Karsdal, Diana Julie Leeming, Erik B. Dam et al. · Osteoarthritis and Cartilage
Open access |
25 Mar 2008 |
220 |
| 42 |
Biomarkers for staging fibrosis and non-alcoholic steatohepatitis in non-alcoholic fatty liver disease (the LITMUS project): a comparative diagnostic accuracy study
Yasaman Vali et al. · The Lancet. Gastroenterology & hepatology
Open access |
21 Mar 2023 |
217 |
| 43 |
The neo-epitope specific PRO-C3 ELISA measures true formation of type III collagen associated with liver and muscle parameters.
Mette Juul Nielsen, Anders Nedergaard, Shu Sun et al. · PubMed
Open access |
2013 |
217 |
| 44 |
Common variants at VRK2 and TCF4 conferring risk of schizophrenia
Stacy Steinberg et al. · Human Molecular Genetics
Open access |
26 Jul 2011 |
216 |
| 45 |
Contribution of the advanced glycation end product pentosidine and of maturation of type I collagen to compressive biomechanical properties of human lumbar vertebrae
S. Viguet‐Carrin, Jean‐Paul Roux, MONIQUE E. ARLOT et al. · Bone
|
11 Jul 2006 |
214 |
| 46 |
Exploration of a potent PI3 kinase/mTOR inhibitor as a novel anti-fibrotic agent in IPF
Paul F. Mercer, Hannah V. Woodcock, Jessica D. Eley et al. · Thorax
Open access |
21 Apr 2016 |
209 |
| 47 |
The coupling of bone and cartilage turnover in osteoarthritis: opportunities for bone antiresorptives and anabolics as potential treatments?
M.A. Karsdal, Anne‐Christine Bay‐Jensen, Rik Jozef Urbain Lories et al. · Annals of the Rheumatic Diseases
|
28 Nov 2013 |
208 |
| 48 |
Safety profile of autologous macrophage therapy for liver cirrhosis
Francesca Moroni et al. · Nature Medicine
Open access |
Oct 2019 |
204 |
| 49 |
Collagen biology and non‐invasive biomarkers of liver fibrosis
Morten A. Karsdal, Samuel Joseph Daniels, Signe Holm Nielsen et al. · Liver International
|
30 Jan 2020 |
200 |
| 50 |
A novel marker for assessment of liver matrix remodeling: An enzyme-linked immunosorbent assay (ELISA) detecting a MMP generated type I collagen neo-epitope (C1M)
DJ. Leeming, Yi He, SS. Veidal et al. · Biomarkers
|
11 Oct 2011 |
194 |