Most cited papers from NsGene (Denmark)

NsGene (Denmark)

What are the most cited papers from NsGene (Denmark)?

The most cited paper from NsGene (Denmark) is "Parkinson-Like Neurodegeneration Induced by Targeted Overexpression of α-Synuclein in the Nigrostriatal System" (Deniz Kirik, Carl Rosenblad, Corinna Bürger et al., 2002), with 625 citations. Next come "Towards a neuroprotective gene therapy for Parkinson’s disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model11Published on the World Wide Web on 10 October 2000." (345) and "Encapsulated Cell Biodelivery of Nerve Growth Factor to the Basal Forebrain in Patients with Alzheimer’s Disease" (166).

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Showing 50 of 62 papers. Every paper is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Parkinson-Like Neurodegeneration Induced by Targeted Overexpression of α-Synuclein in the Nigrostriatal System Deniz Kirik, Carl Rosenblad, Corinna Bürger et al. · Journal of Neuroscience Open access	Apr 2002	625
2	Towards a neuroprotective gene therapy for Parkinson’s disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model11Published on the World Wide Web on 10 October 2000. Anders Björklund, Deniz Kirik, Carl Rosenblad et al. · Brain Research	Dec 2000	345
3	Encapsulated Cell Biodelivery of Nerve Growth Factor to the Basal Forebrain in Patients with Alzheimer’s Disease Maria Eriksdotter, Bengt Linderoth, Göran Lind et al. · Dementia and Geriatric Cognitive Disorders	2012	166
4	Encapsulated cell biodelivery of GDNF: A novel clinical strategy for neuroprotection and neuroregeneration in Parkinson's disease? Olle Lindvall, Lars U. Wahlberg · Experimental Neurology	15 Sep 2007	141
5	Long‐term striatal overexpression of GDNF selectively downregulates tyrosine hydroxylase in the intact nigrostriatal dopamine system Carl Rosenblad, Biljana Georgievska, Deniz Kirik · European Journal of Neuroscience Open access	2003	132
6	Targeted delivery of nerve growth factor via encapsulated cell biodelivery in Alzheimer disease: a technology platform for restorative neurosurgery Lars U. Wahlberg, Göran Lind, Per M. Almqvist et al. · Journal of neurosurgery	Jun 2012	131
7	Neuroprotection in the rat Parkinson model by intrastriatal GDNF gene transfer using a lentiviral vector Biljana Georgievska, Deniz Kirik, Carl Rosenblad et al. · Neuroreport	2002	129
8	Generation of a synthetic mammalian promoter library by modification of sequences spacing transcription factor binding sites Jens Tornøe, Philip Kusk, Teit Eliot Johansen et al. · Gene	Sep 2002	100
9	Positive and negative interactions of GDNF, NTN and ART in developing sensory neuron subpopulations, and their collaboration with neurotrophins Christel Baudet, Åsa Mikaels, Heiner Westphal et al. · Development	15 Oct 2000	94
10	Efficient in vivo protection of nigral dopaminergic neurons by lentiviral gene transfer of a modified Neurturin construct Lone Fjord‐Larsen, Jens Leander Johansen, Philip Kusk et al. · Experimental Neurology	25 May 2005	93
11	Cometin is a novel neurotrophic factor that promotes neurite outgrowth and neuroblast migration in vitro and supports survival of spiral ganglion neurons in vivo Jesper Roland Jørgensen, Anette Fransson, Lone Fjord‐Larsen et al. · Experimental Neurology Open access	3 Oct 2011	87
12	Long-term Delivery of Nerve Growth Factor by Encapsulated Cell Biodelivery in the Göttingen Minipig Basal Forebrain Lone Fjord‐Larsen, Philip Kusk, Jens Tornøe et al. · Molecular Therapy Open access	27 Jul 2010	77
13	Evaluation of Tet-on system to avoid transgene down-regulation in ex vivo gene transfer to the CNS Jens Leander Johansen, Carl Rosenblad, K Andsberg et al. · Gene Therapy	11 Sep 2002	62
14	The use of a recombinant lentiviral vector for ex vivo gene transfer into the rat CNS Ulrica Englund, Cecilia Ericson, Carl Rosenblad et al. · Neuroreport	Dec 2000	61
15	Midbrain expression of Delta-like 1 homologue is regulated by GDNF and is associated with dopaminergic differentiation Nicolaj Strøyer Christophersen, Mette Grønborg, Thomas Nordahl Petersen et al. · Experimental Neurology	25 Jan 2007	57
16	Generation of Regionally Specified Neurons in Expanded Glial Cultures Derived from the Mouse and Human Lateral Ganglionic Eminence Charlotta Skogh, Cecilia Eriksson, Merab Kokaia et al. · Molecular and Cellular Neuroscience	May 2001	54
17	Increased encapsulated cell biodelivery of nerve growth factor in the brain by transposon-mediated gene transfer Lone Fjord‐Larsen, Philip Kusk, Dwaine F. Emerich et al. · Gene Therapy	24 Nov 2011	53
18	Characterization of Meteorin—An Evolutionary Conserved Neurotrophic Factor Jesper Roland Jørgensen, Lachlan H. Thompson, Lone Fjord‐Larsen et al. · Journal of Molecular Neuroscience	3 Mar 2009	52
19	Generation and properties of a new human ventral mesencephalic neural stem cell line Ana Villa, Isabel Liste, Elise T. Courtois et al. · Experimental Cell Research	26 Mar 2009	51
20	GDNF released from encapsulated cells suppresses seizure activity in the epileptic hippocampus Irene Kanter‐Schlifke, Lone Fjord‐Larsen, Philip Kusk et al. · Experimental Neurology	8 Jan 2009	51
21	Induction of dopaminergic neurons from growth factor expanded neural stem/progenitor cell cultures derived from human first trimester forebrain Nicolaj Strøyer Christophersen, Xia Meijer, Jesper Roland Jørgensen et al. · Brain Research Bulletin	22 Jul 2006	50
22	Meteorin is a Chemokinetic Factor in Neuroblast Migration and Promotes Stroke-Induced Striatal Neurogenesis Zhaolu Wang, Nuno Andrade, Malene Torp et al. · Journal of Cerebral Blood Flow & Metabolism Open access	2 Nov 2011	44
23	Increased fiber outgrowth from xeno-transplanted human embryonic dopaminergic neurons with co-implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor Young-Hwan Ahn, Jean‐Charles Bensadoun, Patrick Aebischer et al. · Brain Research Bulletin Open access	Jun 2005	41
24	Activation of silenced transgene expression in neural precursor cell lines by inhibitors of histone deacetylation Nina Rosenqvist, Caroline Hård af Segerstad, Christofer Samuelsson et al. · The Journal of Gene Medicine	20 Mar 2002	41
25	Glial Cell Line-Derived Neurotrophic Factor (GDNF) Receptor α-1 (GFRα1) Is Highly Selective for GDNF versus Artemin Paul J. Carmillo, Lone Dagø, Eric S. Day et al. · Biochemistry	28 Jan 2005	39
26	Quantitative [ 18 F]Fluorodopa/PET and Histology of Fetal Mesencephalic Dopaminergic Grafts to the Striatum of MPTP-Poisoned Minipigs Annette Møller Dall et al. · Cell Transplantation Open access	Nov 2002	38
27	GDNF and neublastin protect against NMDA-induced excitotoxicity in hippocampal slice cultures Christian Bonde, Bjarne Winther Kristensen, Morten Blaabjerg et al. · Neuroreport	Dec 2000	38
28	Tyrosine hydroxylase expression is unstable in a human immortalized mesencephalic cell line—Studies in vitro and after intracerebral grafting in vivo Gesine Paul, Nicolaj Strøyer Christophersen, Heather K. Raymon et al. · Molecular and Cellular Neuroscience	11 Jan 2007	36
29	Enhanced dopaminergic differentiation of human neural stem cells by synergistic effect of Bcl‐xL and reduced oxygen tension Christina Krabbe, Elise T. Courtois, Pia Jensen et al. · Journal of Neurochemistry Open access	17 Jul 2009	34
30	HDAC inhibition amplifies gap junction communication in neural progenitors: Potential for cell-mediated enzyme prodrug therapy Zahidul Islam Khan, Monira Akhtar, Thomas Asklund et al. · Experimental Cell Research	24 May 2007	30
31	Encapsulated cell-based biodelivery of Meteorin is neuroprotective in the quinolinic acid rat model of neurodegenerative disease Jens Tornøe, Malene Torp, Jesper Roland Jørgensen et al. · Restorative Neurology and Neuroscience	2012	28
32	Encapsulated galanin‐producing cells attenuate focal epileptic seizures in the hippocampus Litsa Nikitidou, Malene Torp, Lone Fjord‐Larsen et al. · Epilepsia Open access	18 Nov 2013	28
33	Encapsulated cell device approach for combined electrical stimulation and neurotrophic treatment of the deaf cochlea Wiebke S. Konerding, Hilke Catherina Janßen, Peter Hubka et al. · Hearing Research	25 Apr 2017	26
34	Identification of novel genes regulated in the developing human ventral mesencephalon Jesper Roland Jørgensen, Bengt Juliusson, Karen Friis Henriksen et al. · Experimental Neurology	11 Feb 2006	25
35	Meteorin reverses hypersensitivity in rat models of neuropathic pain Jesper Roland Jørgensen, Xiao‐Jun Xu, H. Moore Arnold et al. · Experimental Neurology	2 Jul 2012	24
36	Increased in vitro and in vivo transgene expression levels mediated through cis‐acting elements Jens Leander Johansen, Jens Tornøe, Arne Møller et al. · The Journal of Gene Medicine	21 Jul 2003	24
37	Lentiviral delivery of Meteorin protects striatal neurons against excitotoxicity and reverses motor deficits in the quinolinic acid rat model Jesper Roland Jørgensen, Dwaine F. Emerich, Chris G. Thanos et al. · Neurobiology of Disease Open access	17 Sep 2010	24
38	Characterization of organotypic ventral mesencephalic cultures from embryonic mice and protection against MPP+ toxicity by GDNF Birthe Jakobsen, Jan Bert Gramsbergen, Annette Møller Dall et al. · European Journal of Neuroscience	Jun 2005	22
39	Unilateral ex vivo gene therapy by GDNF in epileptic rats Avtandil Nanobashvili, Esbjörn Melin, Dwaine F. Emerich et al. · Gene Therapy	21 Nov 2018	21
40	Gene marking of human neural stem/precursor cells using green fluorescent proteins Beatriz Navarro‐Galve, Ana Villa, Carlos Roberto Bueno Júnior et al. · The Journal of Gene Medicine	27 Oct 2004	19
41	A New Versatile and Compact Lentiviral Vector Jens Leander Johansen, Lone Dagø, Jens Tornøe et al. · Molecular Biotechnology	2005	18
42	NS 1231, a novel compound with neurotrophic‐like effects in vitro and in vivo Lone Dagø, Christian Bonde, Dan Peters et al. · Journal of Neurochemistry	25 Mar 2002	16
43	Artemin improves survival of spiral ganglion neurons in vivo and in vitro Athanasia Warnecke, Verena Scheper, Ines Buhr et al. · Neuroreport	7 Apr 2010	16
44	The feasibility of an encapsulated cell approach in an animal deafness model Anette Fransson, Jens Tornøe, Lars U. Wahlberg et al. · Journal of Controlled Release Open access	18 Dec 2017	14
45	Over-Expression of Meteorin Drives Gliogenesis Following Striatal Injury Jordan L. Wright, Charlotte M. Ermine, Jesper Roland Jørgensen et al. · Frontiers in Cellular Neuroscience Open access	4 Jul 2016	14
46	Encapsulate this: the do's and don'ts Gorka Orive, Dwaine F. Emerich, Paul de Vos · Nature Medicine	Mar 2014	13
47	A surgical device for minimally invasive implantation of experimental deep brain stimulation leads in large research animals Kåre Schmidt Ettrup, Jens Tornøe, Jens Christian Hedemann Sørensen et al. · Journal of Neuroscience Methods	26 Jun 2011	13
48	Low-Level Tyrosine Hydroxylase (TH) Expression Allows for the Generation of Stable TH + Cell Lines of Human Neural Stem Cells Isabel Liste, Beatriz Navarro, Jens Leander Johansen et al. · Human Gene Therapy	2004	11
49	IFCC Section R W Burnett, Arthur K. Covington, Nils Fogh-Andersen et al. · Clinical Chemistry and Laboratory Medicine (CCLM) Open access	1995	8
50	NS-417, a Novel Compound with Neurotrophic-Like Effects Lone Dagø, Dan Peters, Morten Meyer et al. · Neurochemical Research	Feb 2002	8

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.