| 1 |
Homogenous 96-Plex PEA Immunoassay Exhibiting High Sensitivity, Specificity, and Excellent Scalability
Erika Assarsson, Martin Lundberg, Göran Holmquist et al. · PLoS ONE
Open access |
22 Apr 2014 |
1,983 |
| 2 |
Homogeneous antibody-based proximity extension assays provide sensitive and specific detection of low-abundant proteins in human blood
Martin Lundberg, Anna Eriksson, Bonnie Robin Tran et al. · Nucleic Acids Research
Open access |
6 Jun 2011 |
793 |
| 3 |
Characterizing proteins and their interactions in cells and tissues using the in situ proximity ligation assay
Ola Söderberg, Karl‐Johan Leuchowius, Mats T. Gullberg et al. · Methods
|
Jul 2008 |
549 |
| 4 |
Proximity Extension Assay in Combination with Next-Generation Sequencing for High-throughput Proteome-wide Analysis
Lotta Wik, Niklas Nordberg, John Broberg et al. · Molecular & Cellular Proteomics
Open access |
2021 |
461 |
| 5 |
Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease
Nicholas T. Ventham et al. · Nature Communications
Open access107 authors |
25 Nov 2016 |
280 |
| 6 |
Detection of Antigen Interactions Ex Vivo by Proximity Ligation Assay: Endogenous Dopamine D2-Adenosine A2A Receptor Complexes in the Striatum
Pierre Trifilieff, M. Rives, Eneko Urizar et al. · BioTechniques
Open access |
Aug 2011 |
254 |
| 7 |
Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells
Spyros Darmanis, Caroline J. Gallant, Voichita Dana Marinescu et al. · Cell Reports
Open access |
31 Dec 2015 |
233 |
| 8 |
In Situ Detection of Phosphorylated Platelet-derived Growth Factor Receptor β Using a Generalized Proximity Ligation Method
Malin Jarvius, Janna Paulsson, Irene Weibrecht et al. · Molecular & Cellular Proteomics
Open access |
14 Jun 2007 |
223 |
| 9 |
Inflammation-related plasma and CSF biomarkers for multiple sclerosis
Jesse Huang, Mohsen Khademi, Lars H. Fugger et al. · Proceedings of the National Academy of Sciences
Open access |
26 May 2020 |
200 |
| 10 |
Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction
Alex S. Genshaft, Shuqiang Li, Caroline J. Gallant et al. · Genome biology
Open access |
19 Sep 2016 |
181 |
| 11 |
Plasma ACE2 predicts outcome of COVID-19 in hospitalized patients
Tue Wenzel Kragstrup, Helene Søgaard Singh, Ida Grundberg et al. · PLoS ONE
Open access |
4 Jun 2021 |
124 |
| 12 |
Multiplexed Homogeneous Proximity Ligation Assays for High-throughput Protein Biomarker Research in Serological Material
Martin Lundberg et al. · Molecular & Cellular Proteomics
Open access |
17 Jan 2011 |
123 |
| 13 |
High throughput proteomics identifies a high-accuracy 11 plasma protein biomarker signature for ovarian cancer
Stefan Enroth, Malin Berggrund, Maria Lycke et al. · Communications Biology
Open access |
20 Jun 2019 |
121 |
| 14 |
ProteinSeq: High-Performance Proteomic Analyses by Proximity Ligation and Next Generation Sequencing
Spyros Darmanis, Rachel Yuan Nong, Johan Vänelid et al. · PLoS ONE
Open access |
29 Sep 2011 |
106 |
| 15 |
A novel multiplexed immunoassay identifies CEA, IL-8 and prolactin as prospective markers for Dukes’ stages A-D colorectal cancers
Sadia Mahboob, Seong Beom Ahn, Harish R. Cheruku et al. · Clinical Proteomics
Open access |
7 Apr 2015 |
95 |
| 16 |
Shrunken Pore Syndrome Is Associated With Increased Levels of Atherosclerosis-Promoting Proteins
Markus Sällman Almén, Jonas Björk, Ulf Nyman et al. · Kidney International Reports
Open access |
13 Sep 2018 |
87 |
| 17 |
Serum proteomic profiling at diagnosis predicts clinical course, and need for intensification of treatment in inflammatory bowel disease
Rahul Kalla et al. · Journal of Crohn s and Colitis
Open access |
9 Nov 2020 |
81 |
| 18 |
Targeted resequencing of candidate genes using selector probes
Henrik Johansson, Magnus Isaksson, Elin Falk Sörqvist et al. · Nucleic Acids Research
Open access |
8 Nov 2010 |
77 |
| 19 |
Strong impact on plasma protein profiles by precentrifugation delay but not by repeated freeze-thaw cycles, as analyzed using multiplex proximity extension assays
Qiujin Shen, Johan Björkesten, Joakim Galli et al. · Clinical Chemistry and Laboratory Medicine (CCLM)
|
17 Oct 2017 |
56 |
| 20 |
Plasma levels of the MMP-9:TIMP-1 complex as prognostic biomarker in breast cancer: a retrospective study
Stine Buch Thorsen, Sarah Louise Christensen, Sidse Ørnbjerg Würtz et al. · BMC Cancer
Open access |
Dec 2013 |
55 |
| 21 |
Evaluation of circulating plasma proteins in breast cancer using Mendelian randomisation
Anders Mälarstig, Felix Graßmann, Leo Dahl et al. · Nature Communications
Open access |
24 Nov 2023 |
54 |
| 22 |
Detection of serological biomarkers by proximity extension assay for detection of colorectal neoplasias in symptomatic individuals
Stine Buch Thorsen, Martin Lundberg, Andrea Villablanca et al. · Journal of Translational Medicine
Open access |
10 Oct 2013 |
51 |
| 23 |
In situ mutation detection and visualization of intratumor heterogeneity for cancer research and diagnostics
Ida Grundberg, Sara Kiflemariam, Marco Mignardi et al. · Oncotarget
Open access |
21 Nov 2013 |
51 |
| 24 |
Biochemical Characterization of the Oxygenation of Unsaturated Fatty Acids by the Dioxygenase and Hydroperoxide Isomerase of Pseudomonas aeruginosa 42A2
Eriel Martínez, Mats Hámberg, Montse Busquets et al. · Journal of Biological Chemistry
Open access |
15 Jan 2010 |
50 |
| 25 |
Rapid Identification of Bio-Molecules Applied for Detection of Biosecurity Agents Using Rolling Circle Amplification
Jenny Göransson, Rongqin Ke, Rachel Yuan Nong et al. · PLoS ONE
Open access |
22 Feb 2012 |
50 |
| 26 |
Aqueous Humor Biomarkers Identify Three Prognostic Groups in Uveal Melanoma
Annemijn P. A. Wierenga, Jinfeng Cao, Henk Mouthaan et al. · Investigative Ophthalmology & Visual Science
Open access |
15 Nov 2019 |
49 |
| 27 |
Cytokine signatures in chronic fatigue syndrome patients: a Case Control Study and the effect of anakinra treatment
Megan E. Roerink, Hans Knoop, Ewald Maria Bronkhorst et al. · Journal of Translational Medicine
Open access |
Dec 2017 |
46 |
| 28 |
Epigenetic mechanisms regulate sex-specific bias in disease manifestations
Sarantis Chlamydas, Mariam Markouli, Dimitrios Strepkos et al. · Journal of Molecular Medicine
Open access |
29 Jun 2022 |
42 |
| 29 |
Visualization and quantification of protein-protein interactions in cells and tissues
Mats T. Gullberg, Ann‐Catrin Andersson · Nature Methods
|
Jun 2010 |
42 |
| 30 |
Temporal Patterns of 14 Blood Biomarker candidates of Cardiac Remodeling in Relation to Prognosis of Patients With Chronic Heart Failure—The Bio‐SHiFT Study
Elke Bouwens, Miloš Branković, Henk Mouthaan et al. · Journal of the American Heart Association
Open access |
14 Feb 2019 |
40 |
| 31 |
Cardiometabolic Biomarkers and Their Temporal Patterns Predict Poor Outcome in Chronic Heart Failure (Bio-SHiFT Study)
Miloš Branković, K. Martijn Akkerhuis, Henk Mouthaan et al. · The Journal of Clinical Endocrinology & Metabolism
Open access |
2 Aug 2018 |
40 |
| 32 |
Bright-Field Microscopy Visualization of Proteins and Protein Complexes by In Situ Proximity Ligation with Peroxidase Detection
Agata Zieba, Carolina Wählby, Fredrik Hjelm et al. · Clinical Chemistry
|
19 Nov 2009 |
40 |
| 33 |
Improving Precision of Proximity Ligation Assay by Amplified Single Molecule Detection
Rongqin Ke, Rachel Yuan Nong, Simon Fredriksson et al. · PLoS ONE
Open access |
16 Jul 2013 |
37 |
| 34 |
A Compendium of Syngeneic, Transplantable Pediatric High-Grade Glioma Models Reveals Subtype-Specific Therapeutic Vulnerabilities
Michael McNicholas, Antonella De Cola, Zahedeh Bashardanesh et al. · Cancer Discovery
Open access |
3 Apr 2023 |
36 |
| 35 |
Assessing the Preanalytical Variability of Plasma and Cerebrospinal Fluid Processing and Its Effects on Inflammation-Related Protein Biomarkers
Jesse Huang, Mohsen Khademi, Örjan Lindhe et al. · Molecular & Cellular Proteomics
Open access |
2021 |
35 |
| 36 |
Dynamic personalized risk prediction in chronic heart failure patients: a longitudinal, clinical investigation of 92 biomarkers (Bio-SHiFT study)
Dominika Klimczak‐Tomaniak, Marie de Bakker, Elke Bouwens et al. · Scientific Reports
Open access |
18 Feb 2022 |
34 |
| 37 |
Utility of temporal profiles of new cardio-renal and pulmonary candidate biomarkers in chronic heart failure
Miloš Branković, K. Martijn Akkerhuis, Henk Mouthaan et al. · International Journal of Cardiology
Open access |
3 Aug 2018 |
32 |
| 38 |
A two-step strategy for identification of plasma protein biomarkers for endometrial and ovarian cancer
Stefan Enroth, Malin Berggrund, Maria Lycke et al. · Clinical Proteomics
Open access |
Dec 2018 |
30 |
| 39 |
Novel means of viral antigen identification: Improved detection of avian influenza viruses by proximity ligation
Joerg Schlingemann, Mikael Leijon, A. Yacoub et al. · Journal of Virological Methods
|
13 Sep 2009 |
29 |
| 40 |
Plasma ACE2 levels predict outcome of COVID-19 in hospitalized patients
Tue Wenzel Kragstrup, Helene Søgaard Singh, Ida Grundberg et al. · medRxiv
PreprintOpen access |
10 Mar 2021 |
27 |
| 41 |
Human Cytomegalovirus (HCMV) Reactivation in the Mammary Gland Induces a Proinflammatory Cytokine Shift in Breast Milk
Tabea Rabe, Katrin Lazar, Christoffer Cambronero et al. · Microorganisms
Open access |
20 Feb 2020 |
27 |
| 42 |
The prevalence and transcriptional activity of the mucosal microbiota of ulcerative colitis patients
Aina Elisabeth Fossum Moen et al. · Scientific Reports
Open access |
16 Nov 2018 |
27 |
| 43 |
Western Blotting via Proximity Ligation for High Performance Protein Analysis
Yanling Liu, Jijuan Gu, Åsa Hagner-McWhirter et al. · Molecular & Cellular Proteomics
Open access |
3 Aug 2011 |
27 |
| 44 |
Longitudinally Measured Fibrinolysis Factors are Strong Predictors of Clinical Outcome in Patients with Chronic Heart Failure: The Bio-SHiFT Study
Victor J. van den Berg, Elke Bouwens, Victor A.W.M. Umans et al. · Thrombosis and Haemostasis
|
28 Oct 2019 |
26 |
| 45 |
Circulating Biomarkers of Cell Adhesion Predict Clinical Outcome in Patients with Chronic Heart Failure
Elke Bouwens, Victor J. van den Berg, K. Martijn Akkerhuis et al. · Journal of Clinical Medicine
Open access |
10 Jan 2020 |
25 |
| 46 |
Shb deficient mice display an augmented TH2 response in peripheral CD4+ T cells
Karin U. Gustafsson, Gabriela Calounova, Fredrik Hjelm et al. · BMC Immunology
Open access |
11 Jan 2011 |
23 |
| 47 |
Use of Proximity Ligation to Screen for Inhibitors of Interactions between Vascular Endothelial Growth Factor A and Its Receptors
Sigrun Gustafsdottir, Stefan Wennström, Simon Fredriksson et al. · Clinical Chemistry
Open access |
23 May 2008 |
23 |
| 48 |
Molecular tools for companion diagnostics
Agata Zieba, Karin Grannas, Ola Söderberg et al. · New Biotechnology
Open access |
23 May 2012 |
20 |
| 49 |
Predictive biomarkers and practical considerations in the management of carfilzomib-associated cardiotoxicity
Nikoletta K. Lendvai, Ioanna Tsakos, Sean M. Devlin et al. · Leukemia & lymphoma/Leukemia and lymphoma
Open access |
8 Jan 2018 |
18 |
| 50 |
Assessment of the within- and between-laboratory repeatability of a commercially available Ostertagia ostertagi milk ELISA
Johannes Charlier, Jan Troeng, Johan Höglund et al. · Veterinary Parasitology
|
16 Apr 2009 |
18 |