Most cited papers from Pharmac
What are the most cited papers from Pharmac?
The most cited paper from Pharmac is "CpG Motifs in Bacterial DNA and Their Immune Effects" (Arthur M. Krieg, 2002), with 2,585 citations. Next come "A pharmacokinetic analysis program (multi) for microcomputer." (2,459) and "Safety and antitumor activity of recombinant soluble Apo2 ligand" (2,234).
Showing 50 of 58 papers. Every paper with more than 278 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | CpG Motifs in Bacterial DNA and Their Immune Effects Arthur M. Krieg · Annual Review of Immunology | Apr 2002 | 2,585 |
| 2 | A pharmacokinetic analysis program (multi) for microcomputer. Kiyoshi Yamaoka, Yusuke Tanigawara, Terumichi Nakagawa et al. · Journal of Pharmacobio-Dynamics | 1981 | 2,459 |
| 3 | Safety and antitumor activity of recombinant soluble Apo2 ligand Avi Ashkenazi, Roger Pai, Sharon Fong et al. · Journal of Clinical Investigation | 15 Jul 1999 | 2,234 |
| 4 | Consolidated Health Economic Evaluation Reporting Standards (CHEERS)—Explanation and Elaboration: A Report of the ISPOR Health Economic Evaluation Publication Guidelines Good Reporting Practices Task Force Don Husereau, Michael Drummond, Stavros Petrou et al. · Value in Health | Mar 2013 | 2,069 |
| 5 | Consolidated Health Economic Evaluation Reporting Standards (CHEERS) statement Don Husereau, Michael Drummond, Stavros Petrou et al. · BMJ | 25 Mar 2013 | 1,772 |
| 6 | Recombinant Leptin for Weight Loss in Obese and Lean Adults Steven B. Heymsfield, Andrew S. Greenberg, Ken Fujioka et al. · JAMA | 27 Oct 1999 | 1,430 |
| 7 | Planar chips technology for miniaturization and integration of separation techniques into monitoring systems A. Manz, David J. Harrison, Elisabeth M. J. Verpoorte et al. · Journal of Chromatography A | Feb 1992 | 1,038 |
| 8 | The health economics of bladder cancer Marc F Botteman, Chris Leo Pashos, Alberto Cesare Luigi Redaelli et al. · PharmacoEconomics | Dec 2003 | 889 |
| 9 | Consensus guidelines for the detection of immunogenic cell death Oliver Kepp et al. · OncoImmunology | 2 Sep 2014 | 842 |
| 10 | Human P-glycoprotein transports cyclosporin A and FK506. Takashi Saeki, Kazumitsu Ueda, Yusuke Tanigawara et al. · Journal of Biological Chemistry | Mar 1993 | 691 |
| 11 | Human P-glycoprotein transports cortisol, aldosterone, and dexamethasone, but not progesterone. Kazumitsu Ueda, Noboru Okamura, Midori Hirai et al. · Journal of Biological Chemistry | Dec 1992 | 677 |
| 12 | Assessing the Gold Standard — Lessons from the History of RCTs Laura E. Bothwell, Jeremy A. Greene, Scott H. Podolsky et al. · New England Journal of Medicine | Jun 2016 | 667 |
| 13 | Interaction of Phytoestrogens with Estrogen Receptors .ALPHA. and .BETA.. Keiko Morito, Toshiharu Hirose, Junei Kinjo et al. · Biological and Pharmaceutical Bulletin | 2001 | 618 |
| 14 | A double‐blind, placebo‐controlled study to assess the mitochondria‐targeted antioxidant MitoQ as a disease‐modifying therapy in Parkinson's disease Barry J. Snow, Fiona L. Rolfe, Michelle Marie Lockhart et al. · Movement Disorders | 21 Jun 2010 | 618 |
| 15 | Aristolochic acid and the etiology of endemic (Balkan) nephropathy Arthur P. Grollman, Shinya Shibutani, Masaaki Moriya et al. · Proceedings of the National Academy of Sciences | 9 Jul 2007 | 608 |
| 16 | Immune Checkpoint Inhibitor Rechallenge After Immune-Related Adverse Events in Patients With Cancer Charles Dolladille, Stéphane Éderhy, Marion Sassier et al. · JAMA Oncology | 16 Apr 2020 | 601 |
| 17 | A Comparison of Two LDL Cholesterol Targets after Ischemic Stroke Pierre Amarenco et al. · New England Journal of Medicine | 18 Nov 2019 | 579 |
| 18 | Characterization of thermal behavior of deep eutectic solvents and their potential as drug solubilization vehicles Henry G. Morrison, Changquan Calvin Sun, Sesha Neervannan · International Journal of Pharmaceutics | 28 May 2009 | 544 |
| 19 | Characterization of Two Alternately Spliced Forms of Phospholipase D1 Scott M. Hammond, John M. Jenco, Shigeru Nakashima et al. · Journal of Biological Chemistry | Feb 1997 | 544 |
| 20 | Validation of Acute Myocardial Infarction Cases in the National Health Insurance Research Database in Taiwan Ching Cheng, Cheng Han Lee, Po Sheng Chen et al. · Journal of Epidemiology | 2014 | 536 |
| 21 | The pattern of neurodegeneration in Huntington's disease: a comparative study of cannabinoid, dopamine, adenosine and GABAA receptor alterations in the human basal ganglia in Huntington's disease Michelle Glass, Mike Dragunow, Richard L. M. Faull · Neuroscience | May 2000 | 532 |
| 22 | Accuracy of medicare claims-based diagnosis of acute myocardial infarction: estimating positive predictive value on the basis of review of hospital records Yuka Kiyota, Sebastian Schneeweiß, Robert J. Glynn et al. · American Heart Journal | 23 Jun 2004 | 531 |
| 23 | Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: Consequences for pravastatin pharmacokinetics Yohei Nishizato · Clinical Pharmacology & Therapeutics | Jun 2003 | 513 |
| 24 | Preclinical Pharmacokinetics of Ranibizumab (rhuFabV2) after a Single Intravitreal Administration Jacques Gaudreault, David Fei, Jeriza Rusit et al. · Investigative Ophthalmology & Visual Science | 26 Jan 2005 | 504 |
| 25 | Broadening Eligibility Criteria to Make Clinical Trials More Representative: American Society of Clinical Oncology and Friends of Cancer Research Joint Research Statement Edward S. Kim et al. · Journal of Clinical Oncology | 2 Oct 2017 | 497 |
| 26 | p185HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor. R M Hudziak, G D Lewis, M Winget et al. · Molecular and Cellular Biology | Mar 1989 | 489 |
| 27 | Interaction of Phytoestrogens with Estrogen Receptors .ALPHA. and .BETA.(II). Keiko Morito, Tohru Aomori, Toshiharu Hirose et al. · Biological and Pharmaceutical Bulletin | 2002 | 464 |
| 28 | Antipsychotics and the Risk of Sudden Cardiac Death Wayne A. Ray, Sarah K Meredith, Purushottam B. Thapa et al. · Archives of General Psychiatry | Dec 2001 | 431 |
| 29 | Rituximab-Dependent Cytotoxicity by Natural Killer Cells Sébastien Dall’Ozzo, Sophie Tartas, Gilles Paintaud et al. · Cancer Research | Jul 2004 | 427 |
| 30 | Charge variants in IgG1 Leslie A. Khawli, Sirj Goswami, Ryan A. Hutchinson et al. · mAbs | Nov 2010 | 419 |
| 31 | A New Model of Patient Tumor-Derived Breast Cancer Xenografts for Preclinical Assays Elisabetta Marangoni, Anne Vincent‐Salomon, Nathalie Auger et al. · Clinical Cancer Research | Jul 2007 | 418 |
| 32 | Acute and clinically relevant drug‐induced liver injury: a population based case‐control study Francisco José de Abajo, Dolores Montero, Mariano Madurga et al. · British Journal of Clinical Pharmacology | 4 Jun 2004 | 412 |
| 33 | Antidepressant Use in Pregnancy and the Risk of Cardiac Defects Krista F. Huybrechts, Kristin K. Palmsten, Jerry Avorn et al. · New England Journal of Medicine | 18 Jun 2014 | 410 |
| 34 | Treat or Eat: Food Insecurity, Cost-related Medication Underuse, and Unmet Needs Seth A. Berkowitz, Hilary Kessler Seligman, Niteesh K. Choudhry · The American Journal of Medicine | 17 Jan 2014 | 392 |
| 35 | Prenatal undernutrition and cognitive function in late adulthood Susanne R. de Rooij, Hans Wouters, Julie E. Yonker et al. · Proceedings of the National Academy of Sciences | 13 Sep 2010 | 368 |
| 36 | New Arylthioindoles: Potent Inhibitors of Tubulin Polymerization. 2. Structure−Activity Relationships and Molecular Modeling Studies Gabriella Martino, Michael Edler, Giuseppe La Regina et al. · Journal of Medicinal Chemistry | 19 Jan 2006 | 365 |
| 37 | Recent advances in the chemistry of organic thiocyanates Thomas Castanheiro, Jean Suffert, Morgan Donnard et al. · Chemical Society Reviews | 11 Dec 2015 | 361 |
| 38 | Aprotinin during Coronary-Artery Bypass Grafting and Risk of Death Sebastian Schneeweiß, John D. Seeger, Joan E. Landon et al. · New England Journal of Medicine | 20 Feb 2008 | 358 |
| 39 | Once-Daily Bronchodilators for Chronic Obstructive Pulmonary Disease: Indacaterol Versus Tiotropium James F. Donohue, Charles M. Fogarty, Jan O. Lötvall et al. · American Journal of Respiratory and Critical Care Medicine | 12 May 2010 | 357 |
| 40 | Developing and understanding biofluid vibrational spectroscopy: a critical review Matthew J. Baker, Shawn R. Hussain, Lila Lovergne et al. · Chemical Society Reviews | 27 Nov 2015 | 352 |
| 41 | Use of β-Blockers and Risk of Fractures Raymond G. Schlienger · JAMA | 14 Sep 2004 | 346 |
| 42 | The Burden of Disease and the Changing Task of Medicine David Shumway Jones, Scott H. Podolsky, Jeremy A. Greene · New England Journal of Medicine | 21 Jun 2012 | 332 |
| 43 | CPG 7909, an Immunostimulatory TLR9 Agonist Oligodeoxynucleotide, as Adjuvant to Engerix-B� HBV Vaccine in Healthy Adults: A Double-Blind Phase I/II Study Curtis Cooper, Heather L. Davis, Mary Lou Morris et al. · Journal of Clinical Immunology | Nov 2004 | 330 |
| 44 | In Vitro Antioxidant Studies on the Benzyl Tetra Isoquinoline Alkaloid Berberine Annie Shirwaikar, Arun Shirwaikar, K. Rajendran et al. · Biological and Pharmaceutical Bulletin | 2006 | 330 |
| 45 | Clinical Pharmacokinetics of Linezolid, a Novel Oxazolidinone Antibacterial Dennis J. Stalker, Gail L. Jungbluth · Clinical Pharmacokinetics | 2003 | 327 |
| 46 | Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: Connecting TGF-β signaling with “Warburg-like” cancer metabolism and L-lactate production Carmela Guido, Diana Whitaker‐Menezes, Claudia Capparelli et al. · Cell Cycle | 15 Aug 2012 | 320 |
| 47 | The Vanilloid Receptor TRPV1 Is Tonically Activated In Vivo and Involved in Body Temperature Regulation Narender R. Gavva, Anthony W. Bannon, Sekhar Surapaneni et al. · Journal of Neuroscience | 28 Mar 2007 | 314 |
| 48 | Novel Hydrogels via Click Chemistry: Synthesis and Potential Biomedical Applications V. Crescenzi, Lisa Cornelio, Chiara Di Meo et al. · Biomacromolecules | 25 May 2007 | 310 |
| 49 | Sodium Intake, ACE Inhibition, and Progression to ESRD Stefan Vegter, Annalisa Perna, Maarten Jacobus Postma et al. · Journal of the American Society of Nephrology | 3 Dec 2011 | 305 |
| 50 | Adverse drug reactions and off-label drug use in paediatric outpatients Benjamin Horen, Jean‐Louis Montastruc, Maryse Lapeyre‐Mestre · British Journal of Clinical Pharmacology | Dec 2002 | 296 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.