| 1 |
Effect of KIT and PDGFRA Mutations on Survival in Patients With Gastrointestinal Stromal Tumors Treated With Adjuvant Imatinib
Heikki Joensuu, Eva Wardelmann, Harri J. Sihto et al. · JAMA Oncology
Open access |
24 Mar 2017 |
192 |
| 2 |
Radium-223 Inhibits Osseous Prostate Cancer Growth by Dual Targeting of Cancer Cells and Bone Microenvironment in Mouse Models
Mari I. Suominen, Katja M. Fagerlund, Jukka P. Rissanen et al. · Clinical Cancer Research
Open access |
31 Mar 2017 |
178 |
| 3 |
Serum TRACP 5b Is a Useful Marker for Monitoring Alendronate Treatment: Comparison With Other Markers of Bone Turnover
Arja Nenonen, Sulin Cheng, Kaisa K. Ivaska et al. · Journal of Bone and Mineral Research
Open access |
Oct 2005 |
167 |
| 4 |
Xylo-oligosaccharides alone or in synbiotic combination with Bifidobacterium animalis subsp. lactis induce bifidogenesis and modulate markers of immune function in healthy adults: a double-blind, placebo-controlled, randomised, factorial cross-over study
Caroline E. Childs, Henna Röytiö, Esa J. Alhoniemi et al. · British Journal Of Nutrition
Open access |
24 Mar 2014 |
166 |
| 5 |
Characterization of pulmonary function in Duchenne Muscular Dystrophy
Oscar Henry Mayer, Richard S. Finkel, Christian Rummey et al. · Pediatric Pulmonology
Open access |
9 Mar 2015 |
156 |
| 6 |
Secreted Tartrate-Resistant Acid Phosphatase 5b is a Marker of Osteoclast Number in Human Osteoclast Cultures and the Rat Ovariectomy Model
Jukka P. Rissanen, Mari I. Suominen, Zhiqi Peng et al. · Calcified Tissue International
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14 Dec 2007 |
151 |
| 7 |
Intracellular Machinery for Matrix Degradation in Bone-Resorbing Osteoclasts
Jukka P. Vääräniemi, Jussi M. Halleen, Katja Kaarlonen et al. · Journal of Bone and Mineral Research
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Sep 2004 |
151 |
| 8 |
Osteoclast-Derived Serum Tartrate-Resistant Acid Phosphatase 5b in Albers-Schonberg Disease (Type II Autosomal Dominant Osteopetrosis)
Sari L Alatalo, Kaisa K. Ivaska, Steven G. Waguespack et al. · Clinical Chemistry
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16 Mar 2004 |
119 |
| 9 |
Survival Benefit With Radium-223 Dichloride in a Mouse Model of Breast Cancer Bone Metastasis
Mari I. Suominen, Jukka P. Rissanen, Rami S. Käkönen et al. · JNCI Journal of the National Cancer Institute
Open access |
16 May 2013 |
91 |
| 10 |
Effects of Lactobacillus helveticus fermented milk on bone cells in vitro
Mirkka Narva, Jussi M. Halleen, Kalervo Väänänen et al. · Life Sciences
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28 Jun 2004 |
88 |
| 11 |
Gut microbiota of healthy elderly NSAID users is selectively modified with the administration of Lactobacillus acidophilus NCFM and lactitol
Marika Björklund, Arthur C. Ouwehand, Sofia D. Forssten et al. · AGE
Open access |
18 Aug 2011 |
67 |
| 12 |
Pim Kinases Promote Migration and Metastatic Growth of Prostate Cancer Xenografts
Niina M. Santio, Sini K. Eerola, Ilkka Paatero et al. · PLoS ONE
Open access |
15 Jun 2015 |
67 |
| 13 |
Differential Effects of Sex Hormones on Peri- and Endocortical Bone Surfaces in Pubertal Girls
Qingju Wang, Markku Alén, Patrick Nicholson et al. · The Journal of Clinical Endocrinology & Metabolism
Open access |
2006 |
58 |
| 14 |
Determination of Nebulizer Droplet Size Distribution: A Method Based on Impactor Refrigeration
Elna Berg, Jan Olof Svensson, Lars Asking · Journal of Aerosol Medicine
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30 May 2007 |
57 |
| 15 |
Consumption ofBifidobacterium lactisBi-07 by healthy elderly adults enhances phagocytic activity of monocytes and granulocytes
Sujira Maneerat, Markus J. Lehtinen, Caroline E. Childs et al. · Journal of Nutritional Science
Open access |
2013 |
53 |
| 16 |
Chronic nonbacterial prostate inflammation in a rat model is associated with changes of gut microbiota that can be modified with a galactoglucomannan‐rich hemicellulose extract in the diet
Yvonne M. Konkol, Anniina Keskitalo, Heikki Vuorikoski et al. · British Journal of Urology
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26 Sep 2018 |
50 |
| 17 |
Prevalence of Helicobacter pylori infection and atrophic gastritis in Latvia
Mārcis Leja, Eva Cine, Dace Rudzīte et al. · European Journal of Gastroenterology & Hepatology
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24 Aug 2012 |
48 |
| 18 |
Effects of Diet-Induced Obesity and Voluntary Wheel Running on Bone Properties in Young Male C57BL/6J Mice
Hongqiang Ma, Sira Torvinen, Mika Silvennoinen et al. · Calcified Tissue International
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12 Mar 2010 |
43 |
| 19 |
Effects of Bioactive Peptide, Valyl-Prolyl-Proline (VPP), and Lactobacillus helveticus Fermented Milk Containing VPP on Bone Loss in Ovariectomized Rats
Mirkka Narva, Jukka P. Rissanen, Jussi M. Halleen et al. · Annals of Nutrition and Metabolism
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2007 |
41 |
| 20 |
Indicators of therapeutic effect in FIT-06, a Phase II trial of a DNA vaccine, GTU®-Multi-HIVB, in untreated HIV-1 infected subjects
Eftyhia Vardas, Ioana Stanescu, Mika Leinonen et al. · Vaccine
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30 Apr 2012 |
39 |
| 21 |
A unique anti-CD115 monoclonal antibody which inhibits osteolysis and skews human monocyte differentiation from M2-polarized macrophages toward dendritic cells
Hélène Haegel, Christine Thioudellet, Rémy Hallet et al. · mAbs
Open access |
24 Jul 2013 |
39 |
| 22 |
Clinical significance of serum BAP, TRACP 5b and ICTP as bone metabolic markers for bone metastasis screening in lung cancer patients
Chuanhao Tang, Yi Liu, Haifeng Qin et al. · Clinica Chimica Acta
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19 Sep 2013 |
38 |
| 23 |
The Mode-of-Action of Targeted Alpha Therapy Radium-223 as an Enabler for Novel Combinations to Treat Patients with Bone Metastasis
Mari I. Suominen, Timothy H. Wilson, Sanna-Maria Käkönen et al. · International Journal of Molecular Sciences
Open access |
10 Aug 2019 |
36 |
| 24 |
Short-Term Changes in Serum PINP Predict Long-Term Changes in Trabecular Bone in the Rat Ovariectomy Model
Jukka P. Rissanen, Mari I. Suominen, Zhiqi Peng et al. · Calcified Tissue International
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24 Jan 2008 |
36 |
| 25 |
Expression of metastasin S100A4 is essential for bone resorption and regulates osteoclast function
Malin C. Erlandsson, Mattias N. D. Svensson, Ing‐Marie Jonsson et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Open access |
2 Jul 2013 |
36 |
| 26 |
Reproducibility of automated simplified voxel-based analysis of PET amyloid ligand [11C]PIB uptake using 30-min scanning data
Sargo Aalto, Noora M. Scheinin, Nina M. Kemppainen et al. · European Journal of Nuclear Medicine and Molecular Imaging
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4 Jun 2009 |
35 |
| 27 |
Blocking oestradiol synthesis pathways with potent and selective coumarin derivatives
Sanna P. Niinivehmas, Pekka A. Postila, Sanna Rauhamäki et al. · Journal of Enzyme Inhibition and Medicinal Chemistry
Open access |
2018 |
34 |
| 28 |
Improving uptake of screening for colorectal cancer
Daiga Šantare, Ilona Kojalo, Teppo Huttunen et al. · European Journal of Gastroenterology & Hepatology
Open access |
25 Mar 2015 |
32 |
| 29 |
O-Sulfated Bacterial Polysaccharides with Low Anticoagulant Activity Inhibit Metastasis
Marjut Borgenström, Anni M. Wärri, Katri Hiilesvuo et al. · Seminars in Thrombosis and Hemostasis
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Jul 2007 |
31 |
| 30 |
Endogenous expression and endocytosis of tartrate-resistant acid phosphatase (TRACP) by osteoblast-like cells
Soledad Pérez‐Amodio, Ilse M. C. Vogels, Ton Schoenmaker et al. · Bone
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6 May 2005 |
30 |
| 31 |
Stromal Activation Associated with Development of Prostate Cancer in Prostate-Targeted Fibroblast Growth Factor 8b Transgenic Mice
Teresa Elo, Eeva M. Valve, Jani Seppänen et al. · Neoplasia
Open access |
Nov 2010 |
30 |
| 32 |
Long-term follow-up on recovery, return to use and sporting activity: a retrospective study of 236 operated colic horses in Finland (2006–2012)
Isa Anna Maria Immonen, Ninja P. Karikoski, Anna Kristina Mykkänen et al. · Acta veterinaria Scandinavica
Open access |
5 Jan 2017 |
29 |
| 33 |
Lactobacillus acidophilussupplementation in human subjects and their resistance to enterotoxigenicEscherichia coliinfection
Arthur C. Ouwehand, Sandra J. M. ten Bruggencate, Arjan J. Schonewille et al. · British Journal Of Nutrition
Open access |
12 Aug 2013 |
29 |
| 34 |
Blocking 17β‐hydroxysteroid dehydrogenase type 1 in endometrial cancer: a potential novel endocrine therapeutic approach
Gonda F.J. Konings, Karlijn M. C. Cornel, Sofia Xanthoulea et al. · The Journal of Pathology
Open access |
16 Nov 2017 |
27 |
| 35 |
Differential Roles of Fibroblast Growth Factor Receptors (FGFR) 1, 2 and 3 in the Regulation of S115 Breast Cancer Cell Growth
Kati M. Tarkkonen, Emeli M. Nilsson, Tiina E. Kähkönen et al. · PLoS ONE
Open access |
21 Nov 2012 |
27 |
| 36 |
Antitumor Activity of Novel Bone-seeking, α-emitting 224Ra-solution in a Breast Cancer Skeletal Metastases Model
Asta Juzeniene, Jenni Bernoulli, Mari I. Suominen et al. · Anticancer Research
Open access |
28 Mar 2018 |
26 |
| 37 |
Elimination of vascular fibrointimal hyperplasia bysomatostatin receptor 1.4 selective agonist
Einari Aavik, Nina‐Maria Luoto, Lubomir Petrov et al. · The FASEB Journal
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26 Mar 2002 |
24 |
| 38 |
Treatment of mosquito bites with ebastine: a field trial
Ari Karppinen, Leena Petman, Antti Pekka Jekunen et al. · Acta Dermato Venereologica
Open access |
Mar 2000 |
23 |
| 39 |
Tracer Level Electrophilic Synthesis and Pharmacokinetics of the Hypoxia Tracer [18F]EF5
Olli Eskola, Tove J. Grönroos, Sarita J. Forsback et al. · Molecular Imaging and Biology
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29 Mar 2011 |
20 |
| 40 |
Improved methods for testing antiresorptive compounds in human osteoclast cultures
Jukka P. Rissanen, Hannele Ylipahkala, Katja M. Fagerlund et al. · Journal of Bone and Mineral Metabolism
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18 Nov 2008 |
18 |
| 41 |
In vitro model of bone to facilitate measurement of adhesion forces and super-resolution imaging of osteoclasts
Takahiro Deguchi, Maria H. Alanne, Elnaz Fazeli et al. · Scientific Reports
Open access |
3 Mar 2016 |
17 |
| 42 |
Models and screening assays for drug discovery in osteoporosis
Jukka P. Rissanen, Jussi M. Halleen · Expert Opinion on Drug Discovery
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16 Nov 2010 |
17 |
| 43 |
Novel 2,7-Diazaspiro[4,4]nonane Derivatives to Inhibit Mouse and Human Osteoclast Activities and Prevent Bone Loss in Ovariectomized Mice without Affecting Bone Formation
Lucile Mounier, Anne Pierre Morel, Yann Ferrandez et al. · Journal of Medicinal Chemistry
Open access |
11 Nov 2020 |
16 |
| 44 |
Effects of the Selective Estrogen Receptor Modulator Ospemifene on Bone in Rats
Lauri Kangas, Pirkko L. Härkönen, Kalervo Väänänen et al. · Hormone and Metabolic Research
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9 Oct 2013 |
16 |
| 45 |
Overexpression of Human Hydroxysteroid (17β) Dehydrogenase 2 Induces Disturbance in Skeletal Development in Young Male Mice
Zhongyi Shen, Zhiqi Peng, Yi Sun et al. · Journal of Bone and Mineral Research
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18 Mar 2008 |
15 |
| 46 |
Increased amount of phosphorylated proinflammatory osteopontin in rheumatoid arthritis synovia is associated to decreased tartrate-resistant acid phosphatase 5B/5A ratio
Jani Luukkonen, Laia Mira‐Pascual, Christina Patlaka et al. · PLoS ONE
Open access |
8 Aug 2017 |
14 |
| 47 |
ZP2307, a novel, cyclic PTH(1-17) analog that augments bone mass in ovariectomized rats
Trine S. R. Neerup, Martin Stahlhut, Jørgen S. Petersen et al. · Bone
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7 Mar 2011 |
13 |
| 48 |
Radiochemotherapy with or without cetuximab for unresectable esophageal cancer: final results of a randomized phase 2 trial (LEOPARD-2)
Dirk Rades, Tobias Bartscht, Peter Hunold et al. · Strahlentherapie und Onkologie
Open access |
12 Jun 2020 |
12 |
| 49 |
Galactoglucomannan-rich hemicellulose extract from Norway spruce ( Picea abies ) exerts beneficial effects on chronic prostatic inflammation and lower urinary tract symptoms in vivo
Yvonne M. Konkol, Heikki Vuorikoski, Johanna M. Tuomela et al. · International Journal of Biological Macromolecules
Open access |
18 Mar 2017 |
12 |
| 50 |
Effects of Ospemifene on Drug Metabolism Mediated by Cytochrome P450 Enzymes in Humans in Vitro and in Vivo
Miia Turpeinen, Jouko Uusitalo, Terhi Lehtinen et al. · International Journal of Molecular Sciences
Open access |
5 Jul 2013 |
12 |