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Institution · Pharming Group (Netherlands)

Most cited papers from Pharming Group (Netherlands)

Pharming Group (Netherlands)

What are the most cited papers from Pharming Group (Netherlands)?

The most cited paper from Pharming Group (Netherlands) is "Striking oil: Another puzzle?" (Gerben Driesprong, Ben Jacobsen, Benjamin Maat, 2008), with 626 citations. Next come "Long-Term Intravenous Treatment of Pompe Disease With Recombinant Human α-Glucosidase From Milk" (355) and "Large scale production of recombinant human lactoferrin in the milk of transgenic cows" (295).

Showing 50 of 60 papers. Every paper with more than 31 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Striking oil: Another puzzle? Gerben Driesprong, Ben Jacobsen, Benjamin Maat · Journal of Financial Economics 28 Jun 2008 626
2 Long-Term Intravenous Treatment of Pompe Disease With Recombinant Human α-Glucosidase From Milk Johanna M. P. van den Hout et al. · PEDIATRICS May 2004 355
3 Large scale production of recombinant human lactoferrin in the milk of transgenic cows Patrick H.C. van Berkel, Mick M. Welling, Marlieke Geerts et al. · Nature Biotechnology May 2002 295
4 Generation Of Transgenic Dairy Cattle Using ‘in vitro’ Embryo Production Paul Krimpenfort, Adriana Rademakers, Will Eyestone et al. · Nature Biotechnology Sep 1991 274
5 Human Lactoferrin and Peptides Derived from Its N Terminus Are Highly Effective against Infections with Antibiotic-Resistant Bacteria Peter H. Nibbering, Elisabeth Ravensbergen, Mick M. Welling et al. · Infection and Immunity Open access Mar 2001 262
6 Recombinant human C1-inhibitor for the treatment of acute angioedema attacks in patients with hereditary angioedema Bruce L. Zuraw, Marco Cicardi, Robyn J. Levy et al. · Journal of Allergy and Clinical Immunology Oct 2010 221
7 N-terminal stretch Arg2, Arg3, Arg4 and Arg5 of human lactoferrin is essential for binding to heparin, bacterial lipopolysaccharide, human lysozyme and DNA Patrick H.C. van Berkel, E. J. Marlieke GEERTS, A. Harry VAN VEEN et al. · Biochemical Journal Open access 15 Nov 1997 208
8 Subclass-specific IgG glycosylation is associated with markers of inflammation and metabolic health Rosina Plomp, L. Renee Ruhaak, Hae‐Won Uh et al. · Scientific Reports Open access 20 Sep 2017 172
9 Therapeutic Targeting of Classical and Lectin Pathways of Complement Protects from Ischemia-Reperfusion-Induced Renal Damage Giuseppe Castellano, Rita Melchiorre, Antonia Loverre et al. · American Journal Of Pathology Open access 11 Feb 2010 150
10 Glycosylated and unglycosylated human lactoferrins both bind iron and show identical affinities towards human lysozyme and bacterial lipopolysaccharide, but differ in their susceptibilities towards tryptic proteolysis P H C van Berkel, Marlieke Geerts, H A van Veen et al. · Biochemical Journal Open access 15 Nov 1995 144
11 Characterization of a Hemoglobin Protease Secreted by the Pathogenic Escherichia coli Strain EB1 Ben R. Otto, Silvy J.M. van Dooren, Jan H. Nuijens et al. · The Journal of Experimental Medicine Open access 21 Sep 1998 138
12 The role of N‐linked glycosylation in the protection of human and bovine lactoferrin against tryptic proteolysis Harrie A. van Veen, Marlieke Geerts, Patrick H.C. van Berkel et al. · European Journal of Biochemistry 26 Jan 2004 132
13 Human Acid -Glucosidase from Rabbit Milk Has Therapeutic Effect in Mice with Glycogen Storage Disease Type II Agnes G. A. Bijvoet, Hans Van Hirtum, Marian A. Kroos et al. · Human Molecular Genetics Open access Nov 1999 127
14 A phase I study of recombinant human C1 inhibitor in asymptomatic patients with hereditary angioedema Martijn B. A. van Doorn, Jacobus Burggraaf, Tijtje van Dam et al. · Journal of Allergy and Clinical Immunology Open access 9 Aug 2005 124
15 Identification of BCAR3 by a random search for genes involved in antiestrogen resistance of human breast cancer cells T van Agthoven, Thecla L. A. van Agthoven, Anita Dekker et al. · The EMBO Journal Open access 15 May 1998 119
16 Recombinant C1 inhibitor in brain ischemic injury Raffaella Gesuete, Claudio Storini, Alessandro Fantin et al. · Annals of Neurology 11 May 2009 117
17 Quantifying the strength of the associations of prototype perceptions with behaviour, behavioural willingness and intentions: a meta-analysis Britt van Lettow, Hein de Vries, Alex Burdorf et al. · Health Psychology Review Review 15 Jul 2014 115
18 Endothelial-to-mesenchymal transition and renal fibrosis in ischaemia/reperfusion injury are mediated by complement anaphylatoxins and Akt pathway Claudia Curci, Giuseppe Castellano, Alessandra Stasi et al. · Nephrology Dialysis Transplantation 23 Jan 2014 110
19 Complement Modulation of Anti-Aging Factor Klotho in Ischemia/Reperfusion Injury and Delayed Graft Function Giuseppe Castellano et al. · American Journal of Transplantation Open access 17 Aug 2015 102
20 Effects of repeated ultrasound-guided transvaginal follicular aspiration on bovine oocyte recovery and subsequent follicular development Arnaud Garcia, Mourad Salaheddine · Theriogenology Sep 1998 100
21 Enhanced Th1 Response to Staphylococcus aureus Infection in Human Lactoferrin-Transgenic Mice C. Guillén, Iain B. McInnes, Diane M. Vaughan et al. · The Journal of Immunology Apr 2002 99
22 Recombinant human C1‐inhibitor in the treatment of acute angioedema attacks Goda Choi, Maarten R. Soeters, Henriette Farkas et al. · Transfusion 22 May 2007 98
23 The role of smoking in social networks on smoking cessation and relapse among adults: A longitudinal study David J. Blok, Sake J. de Vlas, Pepijn van Empelen et al. · Preventive Medicine Open access 17 Feb 2017 93
24 Recombinant human C1-esterase inhibitor relieves symptoms of hereditary angioedema attacks: phase 3, randomized, placebo-controlled trial Marc A. Riedl, Jonathan A. Bernstein, Henry Li et al. · Annals of Allergy Asthma & Immunology 6 Jan 2014 89
25 Heterogeneity in utilization of N-glycosylation sites Asn624 and Asn138 in human lactoferrin: a study with glycosylation-site mutants Patrick H.C. van Berkel, Harry A. van Veen, Marlieke Geerts et al. · Biochemical Journal Open access Oct 1996 89
26 Treatment of COVID-19 With Conestat Alfa, a Regulator of the Complement, Contact Activation and Kallikrein-Kinin System Pascal Urwyler, Stephan Moser, Panteleimon Charitos et al. · Frontiers in Immunology Open access 14 Aug 2020 85
27 The Membrane Attack Complex of the Complement System Is Essential for Rapid Wallerian Degeneration Valeria Ramaglia, Rosalind H.M. King, Michelle Nourallah et al. · Journal of Neuroscience Open access 18 Jul 2007 84
28 Recombinant Human Acid -Glucosidase: High Level Production in Mouse Milk, Biochemical Characteristics, Correction of Enzyme Deficiency in GSDII KO Mice Agnes G. A. Bijvoet, Marian A. Kroos, Frank R. Pieper et al. · Human Molecular Genetics Open access Oct 1998 82
29 Complement-dependent NADPH oxidase enzyme activation in renal ischemia/reperfusion injury Simona Simone, Federica Rascio, Giuseppe Castellano et al. · Free Radical Biology and Medicine 10 Jul 2014 80
30 The N-terminal Arg2, Arg3 and Arg4 of human lactoferrin interact with sulphated molecules but not with the receptor present on Jurkat human lymphoblastic T-cells Dominique Legrand, Patrick H.C. van Berkel, Valérie Salmon et al. · Biochemical Journal Open access Nov 1997 76
31 Angioedema attacks in patients with hereditary angioedema: Local manifestations of a systemic activation process Zonne L. M. Hofman, Anurag Relan, Sacha Sergio Zeerleder et al. · Journal of Allergy and Clinical Immunology Open access 29 May 2016 76
32 Characterization of Recombinant Human Lactoferrin Secreted in Milk of Transgenic Mice Jan H. Nuijens, Patrick H.C. van Berkel, Marlieke Geerts et al. · Journal of Biological Chemistry Open access Mar 1997 72
33 Elevated D ‐dimers in attacks of hereditary angioedema are not associated with increased thrombotic risk Avner Reshef, Andrea Zanichelli, Hilary J Longhurst et al. · Allergy Open access 30 Jan 2015 72
34 Organization of the bovine casein gene locus Monique Rijnkels, Patricia M. Kooiman, Harry Boer et al. · Mammalian Genome Feb 1997 72
35 Production of recombinant human type I procollagen homotrimer in the mammary gland of transgenic mice P. David Toman, Frank R. Pieper, Naomi Sakai et al. · Transgenic Research Dec 1999 68
36 Developing efficient strategies for the generation of transgenic cattle which produce biopharmaceuticals in milk M. F. Brink, Matthew Bishop, Frank R. Pieper · Theriogenology 2000 66
37 A novel ex vivo skin model to study the susceptibility of the dermatophyte Trichophyton rubrum to photodynamic treatment in different growth phases Threes G. M. Smijs, Joke A. Bouwstra, Hans J. Schuitmaker et al. · Journal of Antimicrobial Chemotherapy 9 Jan 2007 65
38 Recombinant human C1 esterase inhibitor for prophylaxis of hereditary angio-oedema: a phase 2, multicentre, randomised, double-blind, placebo-controlled crossover trial Marc A. Riedl, Vesna Grivcheva‐Panovska, Dumitru Moldovan et al. · The Lancet 26 Jul 2017 64
39 Characterization of recombinant human C1 inhibitor secreted in milk of transgenic rabbits Harrie A. van Veen, Jaco Koiter, Carla J.M. Vogelezang et al. · Journal of Biotechnology 17 Sep 2012 60
40 Target levels of functional C1‐inhibitor in hereditary angioedema C. Erik Hack, Anurag Relan, Edwin S. van Amersfoort et al. · Allergy 19 Sep 2011 58
41 The inhibition of mast cell activation by neutrophil lactoferrin: uptake by mast cells and interaction with tryptase, chymase and cathepsin G Shaoheng He, Alan R. McEuen, Sally A Blewett et al. · Biochemical Pharmacology Mar 2003 56
42 Efficacy and safety of recombinant human C1‐inhibitor for the treatment of attacks of hereditary angioedema: European open‐label extension study Dumitru Moldovan, Avner Reshef, J E Fabiani et al. · Clinical & Experimental Allergy 21 Feb 2012 53
43 Complement inhibition attenuates acute kidney injury after ischemia-reperfusion and limits progression to renal fibrosis in mice Juan Sebastian Danobeitia, Martynas Ziemelis, Xiaobo Ma et al. · PLoS ONE Open access 23 Aug 2017 50
44 Efficacy and safety of recombinant C1 inhibitor for the treatment of hereditary angioedema attacks: a North American open-label study Marc A. Riedl, Robyn J. Levy, Daniel Suez et al. · Annals of Allergy Asthma & Immunology 6 Mar 2013 49
45 Human Lactoferrin in the Milk of Transgenic Mice Increases Intestinal Growth in Ten-Day-Old Suckling Neonates P. Zhang, Valerie Sawicki, Alan S. Lewis et al. · Advances in experimental medicine and biology Book chapter 2001 49
46 Effect of Monovalent and Divalent Cations on the Photoinactivation of Bacteria with meso-Substituted Cationic Porphyrins Saskia A. G. Lambrechts, Maurice C. G. Aalders, Diana H. Langeveld‐Klerks et al. · Photochemistry and Photobiology 2004 48
47 Systematic review of the mechanisms and evidence behind the hypocholesterolaemic effects of HPMC, pectin and chitosan in animal trials Toon van der Gronde, Anita Hartog, Charlotte van Hees et al. · Food Chemistry ReviewOpen access 16 Dec 2015 46
48 The protein structure of recombinant human lactoferrin produced in the milk of transgenic cows closely matches the structure of human milk-derived lactoferrin Ellen A. J. Thomassen, Harrie A. van Veen, Patrick H.C. van Berkel et al. · Transgenic Research Open access 28 Jul 2005 44
49 Inhibition of complement improves graft outcome in a pig model of kidney autotransplantation Pierre-Olivier Delpech, Raphaël Thuillier, Thibault SaintYves et al. · Journal of Translational Medicine Open access 23 Sep 2016 43
50 Recombinant human C1 inhibitor for the prophylaxis of hereditary angioedema attacks: a pilot study Avner Reshef, Dumitru Moldovan, Krystyna Obtułowicz et al. · Allergy 5 Nov 2012 43

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.