| 1 |
Secukinumab in Plaque Psoriasis — Results of Two Phase 3 Trials
Richard G B Langley, Boni Elizabeth Elewski, Mark Lebwohl et al. · New England Journal of Medicine
Open access |
9 Jul 2014 |
2,004 |
| 2 |
Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)
Craig L. Leonardi, Alexa B. Kimball, Kim Alexander Papp et al. · The Lancet
|
May 2008 |
1,876 |
| 3 |
Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2)
Kim Alexander Papp, Richard G B Langley, Mark Lebwohl et al. · The Lancet
|
May 2008 |
1,365 |
| 4 |
Long-term management of moderate-to-severe atopic dermatitis with dupilumab and concomitant topical corticosteroids (LIBERTY AD CHRONOS): a 1-year, randomised, double-blinded, placebo-controlled, phase 3 trial
Andrew Blauvelt et al. · The Lancet
Open access |
4 May 2017 |
1,269 |
| 5 |
Etanercept and clinical outcomes, fatigue, and depression in psoriasis: double-blind placebo-controlled randomised phase III trial
Stephen Keith Tyring, Alice Bendix Gottlieb, Kim Alexander Papp et al. · The Lancet
|
22 Dec 2005 |
1,075 |
| 6 |
Infliximab induction and maintenance therapy for moderate-to-severe psoriasis: a phase III, multicentre, double-blind trial
Kristian Reich, Frank Oliver Nestle, Kim Alexander Papp et al. · The Lancet
|
Oct 2005 |
1,049 |
| 7 |
Joint AAD-NPF guidelines of care for the management and treatment of psoriasis with biologics
Alan Menter et al. · Journal of the American Academy of Dermatology
|
13 Feb 2019 |
970 |
| 8 |
Brodalumab, an Anti–Interleukin-17–Receptor Antibody for Psoriasis
Kim Alexander Papp, Craig L. Leonardi, Alan Menter et al. · New England Journal of Medicine
|
28 Mar 2012 |
941 |
| 9 |
Efficacy and safety of guselkumab, an anti-interleukin-23 monoclonal antibody, compared with adalimumab for the continuous treatment of patients with moderate to severe psoriasis: Results from the phase III, double-blinded, placebo- and active comparator–controlled VOYAGE 1 trial
Andrew Blauvelt, Kim Alexander Papp, Christopher E.M. Griffiths et al. · Journal of the American Academy of Dermatology
Open access |
4 Jan 2017 |
898 |
| 10 |
Adalimumab therapy for moderate to severe psoriasis: A randomized, controlled phase III trial
Alan Menter, Stephen Keith Tyring, Kenneth B. Gordon et al. · Journal of the American Academy of Dermatology
|
3 Dec 2007 |
892 |
| 11 |
Phase 3 Trials of Ixekizumab in Moderate-to-Severe Plaque Psoriasis
Kenneth B. Gordon, Andrew Blauvelt, Kim Alexander Papp et al. · New England Journal of Medicine
Open access |
8 Jun 2016 |
855 |
| 12 |
Comparison of ixekizumab with etanercept or placebo in moderate-to-severe psoriasis (UNCOVER-2 and UNCOVER-3): results from two phase 3 randomised trials
Christopher E.M. Griffiths, Kristian Reich, Mark Lebwohl et al. · The Lancet
|
13 Jun 2015 |
842 |
| 13 |
Phase 3 Studies Comparing Brodalumab with Ustekinumab in Psoriasis
Mark Lebwohl et al. · New England Journal of Medicine
Open access |
30 Sep 2015 |
826 |
| 14 |
Two Phase 3 Trials of Adalimumab for Hidradenitis Suppurativa
Alexa B. Kimball et al. · New England Journal of Medicine
|
3 Aug 2016 |
804 |
| 15 |
Efficacy and safety results from the randomized controlled comparative study of adalimumab vs. methotrexate vs. placebo in patients with psoriasis (CHAMPION)
J.‐H. Saurat, George Stingl, Louis Dubertret et al. · British Journal of Dermatology
Open access |
28 Nov 2007 |
729 |
| 16 |
A global phase III randomized controlled trial of etanercept in psoriasis: safety, efficacy, and effect of dose reduction
Kim Alexander Papp, Stephen Keith Tyring, Mourad Lahfa et al. · British Journal of Dermatology
|
Jun 2005 |
697 |
| 17 |
Efficacy and safety of risankizumab in moderate-to-severe plaque psoriasis (UltIMMa-1 and UltIMMa-2): results from two double-blind, randomised, placebo-controlled and ustekinumab-controlled phase 3 trials
Kenneth B. Gordon, Bruce E Strober, Mark Lebwohl et al. · The Lancet
|
Aug 2018 |
681 |
| 18 |
Apremilast, an oral phosphodiesterase 4 (PDE4) inhibitor, in patients with moderate to severe plaque psoriasis: Results of a phase III, randomized, controlled trial (Efficacy and Safety Trial Evaluating the Effects of Apremilast in Psoriasis [ESTEEM] 1)
Kim Alexander Papp, Kristian Reich, Craig L. Leonardi et al. · Journal of the American Academy of Dermatology
Open access |
16 Jun 2015 |
680 |
| 19 |
Tralokinumab for moderate‐to‐severe atopic dermatitis: results from two 52‐week, randomized, double‐blind, multicentre, placebo‐controlled phase III trials (ECZTRA 1 and ECZTRA 2)*
Andreas Wollenberg et al. · British Journal of Dermatology
Open access |
Oct 2020 |
627 |
| 20 |
Golimumab, a new human tumor necrosis factor α antibody, administered every four weeks as a subcutaneous injection in psoriatic arthritis: Twenty‐four–week efficacy and safety results of a randomized, placebo‐controlled study
Arthur Kavanaugh, Iain B. McInnes, Philip J. Mease et al. · Arthritis & Rheumatism
|
30 Mar 2009 |
605 |
| 21 |
A Novel Targeted T-Cell Modulator, Efalizumab, for Plaque Psoriasis
Mark Lebwohl, Stephen Keith Tyring, Tiffani K. Hamilton et al. · New England Journal of Medicine
Open access |
19 Nov 2003 |
582 |
| 22 |
Once-daily upadacitinib versus placebo in adolescents and adults with moderate-to-severe atopic dermatitis (Measure Up 1 and Measure Up 2): results from two replicate double-blind, randomised controlled phase 3 trials
Emma Guttman‐Yassky, Henrique D. Teixeira, Eric Lawrence Simpson et al. · The Lancet
|
20 May 2021 |
574 |
| 23 |
Efficacy and safety of dupilumab in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical treatments: a randomised, placebo-controlled, dose-ranging phase 2b trial
Diamant Thaçi et al. · The Lancet
|
20 Oct 2015 |
573 |
| 24 |
Tildrakizumab versus placebo or etanercept for chronic plaque psoriasis (reSURFACE 1 and reSURFACE 2): results from two randomised controlled, phase 3 trials
Kristian Reich, Kim Alexander Papp, Andrew Blauvelt et al. · The Lancet
|
6 Jun 2017 |
565 |
| 25 |
Efficacy and Safety of Dupilumab in Adolescents With Uncontrolled Moderate to Severe Atopic Dermatitis
Eric Lawrence Simpson et al. · JAMA Dermatology
Open access |
6 Nov 2019 |
519 |
| 26 |
A randomized comparison of continuous vs. intermittent infliximab maintenance regimens over 1 year in the treatment of moderate-to-severe plaque psoriasis
Alan Menter, Steven R. Feldman, Gerald D. Weinstein et al. · Journal of the American Academy of Dermatology
|
7 Sep 2006 |
518 |
| 27 |
Risankizumab versus Ustekinumab for Moderate-to-Severe Plaque Psoriasis
Kim Alexander Papp, Andrew Blauvelt, Michael Bukhalo et al. · New England Journal of Medicine
Open access |
19 Apr 2017 |
516 |
| 28 |
Prevalence of rheumatologist-diagnosed psoriatic arthritis in patients with psoriasis in European/North American dermatology clinics
Philip J. Mease, Dafna D. Gladman, Kim Alexander Papp et al. · Journal of the American Academy of Dermatology
|
24 Aug 2013 |
511 |
| 29 |
Clinical response to adalimumab treatment in patients with moderate to severe psoriasis: Double-blind, randomized controlled trial and open-label extension study
Kenneth B. Gordon, Richard G B Langley, Craig L. Leonardi et al. · Journal of the American Academy of Dermatology
|
11 Aug 2006 |
510 |
| 30 |
Efficacy and Safety of Upadacitinib vs Dupilumab in Adults With Moderate-to-Severe Atopic Dermatitis
Andrew Blauvelt, Henrique D. Teixeira, Eric Lawrence Simpson et al. · JAMA Dermatology
Open access |
4 Aug 2021 |
504 |
| 31 |
Joint AAD-NPF guidelines of care for the management and treatment of psoriasis with awareness and attention to comorbidities
Craig A. Elmets et al. · Journal of the American Academy of Dermatology
|
13 Feb 2019 |
503 |
| 32 |
A prospective phase III, randomized, double‐blind, placebo‐controlled study of brodalumab in patients with moderate‐to‐severe plaque psoriasis
Kim Alexander Papp, Kristian Reich, Carle F. Paul et al. · British Journal of Dermatology
Open access |
25 Feb 2016 |
470 |
| 33 |
Increase in TNF-α and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)
Michelle Anne Lowes, Francesca Chamian, Maria Veronica Abello et al. · Proceedings of the National Academy of Sciences
Open access |
27 Dec 2005 |
454 |
| 34 |
Bimekizumab versus Secukinumab in Plaque Psoriasis
Kristian Reich, Richard Bruce Warren, Mark Lebwohl et al. · New England Journal of Medicine
|
23 Apr 2021 |
427 |
| 35 |
Phase 2 Trial of Selective Tyrosine Kinase 2 Inhibition in Psoriasis
Kim Alexander Papp, Kenneth B. Gordon, Diamant Thaçi et al. · New England Journal of Medicine
Open access |
12 Sep 2018 |
424 |
| 36 |
Topical tofacitinib for atopic dermatitis: a phase II a randomized trial
Robert Bissonnette, Kim Alexander Papp, Yves P. Poulin et al. · British Journal of Dermatology
Open access |
16 Jul 2016 |
422 |
| 37 |
Long-term safety of ustekinumab in patients with moderate-to-severe psoriasis: final results from 5 years of follow-up
Kim Alexander Papp, Christopher E.M. Griffiths, Kenneth B. Gordon et al. · British Journal of Dermatology
|
10 Jan 2013 |
415 |
| 38 |
Efficacy and Safety of Abrocitinib in Patients With Moderate-to-Severe Atopic Dermatitis
Jonathan I. Silverberg, Eric Lawrence Simpson, Jacob Pontoppidan Thyssen et al. · JAMA Dermatology
Open access |
3 Jun 2020 |
405 |
| 39 |
Efficacy and Safety of Pimecrolimus Cream in the Long-Term Management of Atopic Dermatitis in Children
Ulrich Wahn, Jan Dositheus Bos, Mark J. D. Goodfield et al. · PEDIATRICS
|
Jul 2002 |
405 |
| 40 |
Tofacitinib versus etanercept or placebo in moderate-to-severe chronic plaque psoriasis: a phase 3 randomised non-inferiority trial
Hervé Bachelez, Peter C.M. van de Kerkhof, Robert Strohal et al. · The Lancet
Open access |
6 Jun 2015 |
403 |
| 41 |
Efficacy and safety of dupilumab with concomitant topical corticosteroids in children 6 to 11 years old with severe atopic dermatitis: A randomized, double-blinded, placebo-controlled phase 3 trial
Amy S. Paller et al. · Journal of the American Academy of Dermatology
Open access |
20 Jun 2020 |
399 |
| 42 |
Efalizumab for Patients With Moderate to Severe Plaque Psoriasis
Kenneth B. Gordon, Kim Alexander Papp, Tiffani K. Hamilton et al. · JAMA
|
16 Dec 2003 |
397 |
| 43 |
Deucravacitinib versus placebo and apremilast in moderate to severe plaque psoriasis: Efficacy and safety results from the 52-week, randomized, double-blinded, placebo-controlled phase 3 POETYK PSO-1 trial
April Wang Armstrong, Melinda Gooderham, Richard Bruce Warren et al. · Journal of the American Academy of Dermatology
Open access |
9 Jul 2022 |
371 |
| 44 |
Upadacitinib in adults with moderate to severe atopic dermatitis: 16-week results from a randomized, placebo-controlled trial
Emma Guttman‐Yassky, Diamant Thaçi, Aileen L. Pangan et al. · Journal of Allergy and Clinical Immunology
Open access |
28 Nov 2019 |
365 |
| 45 |
Efficacy and safety of secukinumab in the treatment of moderate-to-severe plaque psoriasis: a randomized, double-blind, placebo-controlled phase II dose-ranging study
Kim Alexander Papp, Richard G B Langley, Bárður Sigurgeirsson et al. · British Journal of Dermatology
|
27 Oct 2012 |
361 |
| 46 |
A randomized, double-blind, placebo-controlled phase III study evaluating efficacy and tolerability of 2 courses of alefacept in patients with chronic plaque psoriasis
Gerald G. Krueger, Kim Alexander Papp, Dow B. Stough et al. · Journal of the American Academy of Dermatology
|
25 Nov 2002 |
348 |
| 47 |
Dupilumab: A review of its use in the treatment of atopic dermatitis
Melinda Gooderham, Hwanhee Hong, Panteha Eshtiaghi et al. · Journal of the American Academy of Dermatology
|
19 Feb 2018 |
343 |
| 48 |
Efficacy and safety of tofacitinib, an oral Janus kinase inhibitor, in the treatment of psoriasis: a Phase 2b randomized placebo-controlled dose-ranging study
Kim Alexander Papp, Alan Menter, Bruce E Strober et al. · British Journal of Dermatology
|
27 Aug 2012 |
339 |
| 49 |
Tofacitinib, an oral Janus kinase inhibitor, for the treatment of chronic plaque psoriasis: results from two randomized, placebo-controlled, phase III trials
Kim Alexander Papp, Alan Menter, Mai Abe et al. · British Journal of Dermatology
Open access |
7 Jul 2015 |
328 |
| 50 |
Tralokinumab plus topical corticosteroids for the treatment of moderate‐to‐severe atopic dermatitis: results from the double‐blind, randomized, multicentre, placebo‐controlled phase III ECZTRA 3 trial*
Jonathan I. Silverberg, D. Toth, Thomas R.M. Bieber et al. · British Journal of Dermatology
Open access |
Oct 2020 |
327 |