| 1 |
A Pilot Randomised Trial of Induced Blood-Stage Plasmodium falciparum Infections in Healthy Volunteers for Testing Efficacy of New Antimalarial Drugs
James S. McCarthy, Silvana Sekuloski, Paul Griffin et al. · PLoS ONE
Open access |
22 Aug 2011 |
185 |
| 2 |
Safety, tolerability, pharmacokinetics, and immunogenicity of a human monoclonal antibody targeting the G glycoprotein of henipaviruses in healthy adults: a first-in-human, randomised, controlled, phase 1 study
Elliott Geoffrey Playford et al. · The Lancet Infectious Diseases
Open access |
3 Feb 2020 |
158 |
| 3 |
A phase 1, randomized, placebo-controlled study to evaluate the safety and immunogenicity of an mRNA-based RSV prefusion F protein vaccine in healthy younger and older adults
Antonios O. Aliprantis, Christine A. Shaw, Paul Griffin et al. · Human Vaccines & Immunotherapeutics
Open access |
29 Oct 2020 |
154 |
| 4 |
A controlled human malaria infection model enabling evaluation of transmission-blocking interventions
Katharine A. Collins, Claire Y. T. Wang, Matthew Adams et al. · Journal of Clinical Investigation
Open access |
Feb 2018 |
153 |
| 5 |
A Phase II pilot trial to evaluate safety and efficacy of ferroquine against early Plasmodium falciparum in an induced blood-stage malaria infection study
James S. McCarthy, Thomas Rückle, Elhadj Djeriou et al. · Malaria Journal
Open access |
13 Sep 2016 |
130 |
| 6 |
Safety, tolerability, acceptability and immunogenicity of an influenza vaccine delivered to human skin by a novel high-density microprojection array patch (Nanopatch™)
Germain J. P. Fernando, Julian Hickling, Cesar M. Jayashi Flores et al. · Vaccine
Open access |
17 May 2018 |
129 |
| 7 |
Safety, tolerability, pharmacokinetics, and activity of the novel long-acting antimalarial DSM265: a two-part first-in-human phase 1a/1b randomised study
James S. McCarthy, Julie Lotharius, Thomas Rückle et al. · The Lancet Infectious Diseases
Open access |
28 Mar 2017 |
129 |
| 8 |
Efficacy of OZ439 (artefenomel) against early Plasmodium falciparum blood-stage malaria infection in healthy volunteers
James S. McCarthy, Mark Baker, Peter K O'Rourke et al. · Journal of Antimicrobial Chemotherapy
Open access |
5 Jun 2016 |
106 |
| 9 |
A Phase 1 Trial of MSP2-C1, a Blood-Stage Malaria Vaccine Containing 2 Isoforms of MSP2 Formulated with Montanide® ISA 720
James S. McCarthy, Joanne K. Marjason, Suzanne L. Elliott et al. · PLoS ONE
Open access |
19 Sep 2011 |
101 |
| 10 |
Evaluation of safety and immunogenicity of a group A streptococcus vaccine candidate (MJ8VAX) in a randomized clinical trial
Silvana Sekuloski, Michael R. Batzloff, Paul Griffin et al. · PLoS ONE
Open access |
2 Jul 2018 |
88 |
| 11 |
A Single-Dose Combination Study with the Experimental Antimalarials Artefenomel and DSM265 To Determine Safety and Antimalarial Activity against Blood-Stage Plasmodium falciparum in Healthy Volunteers
James S. McCarthy, Thomas Rückle, Suzanne L. Elliott et al. · Antimicrobial Agents and Chemotherapy
Open access |
5 Nov 2019 |
84 |
| 12 |
Safety and Reproducibility of a Clinical Trial System Using Induced Blood Stage Plasmodium vivax Infection and Its Potential as a Model to Evaluate Malaria Transmission
Paul Griffin, Cielo J. Pasay, Suzanne L. Elliott et al. · PLoS neglected tropical diseases
Open access |
8 Dec 2016 |
69 |
| 13 |
Plasmodium vivax Controlled Human Malaria Infection – Progress and Prospects
Ruth Payne, Paul Griffin, James S. McCarthy et al. · Trends in Parasitology
ReviewOpen access |
10 Dec 2016 |
67 |
| 14 |
Ascending dose‐controlled trial of beloranib, a novel obesity treatment for safety, tolerability, and weight loss in obese women
Thomas E. Hughes, D. D. Kim, Joanne K. Marjason et al. · Obesity
|
20 Mar 2013 |
67 |
| 15 |
A Plasmodium vivax experimental human infection model for evaluating efficacy of interventions
Katharine A. Collins, Claire Y. T. Wang, Matthew Douglas Adams et al. · Journal of Clinical Investigation
Open access |
11 Feb 2020 |
65 |
| 16 |
Efficacy and safety of beloranib for weight loss in obese adults: a randomized controlled trial
D. D. Kim, Janakan Krishnarajah, Stephen Lillioja et al. · Diabetes Obesity and Metabolism
|
3 Mar 2015 |
63 |
| 17 |
DSM265 at 400 Milligrams Clears Asexual Stage Parasites but Not Mature Gametocytes from the Blood of Healthy Subjects Experimentally Infected with Plasmodium falciparum
Katharine A. Collins, Thomas Rückle, Suzanne L. Elliott et al. · Antimicrobial Agents and Chemotherapy
Open access |
8 Mar 2019 |
57 |
| 18 |
Preclinical characterization of bemarituzumab, an anti-FGFR2b antibody for the treatment of cancer
Hong Xiang, Abigael G. Chan, Ago B. Ahene et al. · mAbs
Open access |
2021 |
53 |
| 19 |
Qualitative study investigating the underlying motivations of healthy participants in phase I clinical trials
Kerry J. Manton, Cassandra Gauld, Katherine Marie White et al. · BMJ Open
Open access |
2019 |
50 |
| 20 |
Safety, acceptability and tolerability of uncoated and excipient-coated high density silicon micro-projection array patches in human subjects
Paul Griffin, Suzanne L. Elliott, Kenia G. Krauer et al. · Vaccine
Open access |
23 Oct 2017 |
45 |
| 21 |
Linking Murine and Human Plasmodium falciparum Challenge Models in a Translational Path for Antimalarial Drug Development
James S. McCarthy, Louise Marquart, Silvana Sekuloski et al. · Antimicrobial Agents and Chemotherapy
Open access |
5 Apr 2016 |
45 |
| 22 |
Concomitant or sequential administration of live attenuated Japanese encephalitis chimeric virus vaccine and yellow fever 17D vaccine
Peter Nasveld, Joanne K. Marjason, Sonya Bennett et al. · Human Vaccines
Open access |
Nov 2010 |
41 |
| 23 |
A first-in-human study of BLZ-100 (tozuleristide) demonstrates tolerability and safety in skin cancer patients
Miko Yamada, Dennis Michael Miller, Melinda Lowe et al. · Contemporary Clinical Trials Communications
Open access |
4 Aug 2021 |
40 |
| 24 |
Growth Rate of Plasmodium falciparum: Analysis of Parasite Growth Data from Malaria Volunteer Infection Studies
Leesa F. Wockner, Isabell Hoffmann, Lachlan Webb et al. · The Journal of Infectious Diseases
Open access |
29 Oct 2019 |
39 |
| 25 |
Defining the Antimalarial Activity of Cipargamin in Healthy Volunteers Experimentally Infected with Blood-Stage Plasmodium falciparum
James S. McCarthy, Azrin N. Abd‐Rahman, Katharine A. Collins et al. · Antimicrobial Agents and Chemotherapy
Open access |
16 Nov 2020 |
34 |
| 26 |
An escalating dose study to assess the safety, tolerability and immunogenicity of a Herpes Simplex Virus DNA vaccine, COR-1
J.L. Dutton, Wai-Ping Woo, Janin Chandra et al. · Human Vaccines & Immunotherapeutics
Open access |
31 Aug 2016 |
34 |
| 27 |
Phase 1 safety and immunogenicity trial of the Plasmodium falciparum blood-stage malaria vaccine AMA1-C1/ISA 720 in Australian adults
Mark A. Pierce, Ruth D. Ellis, Laura B. Martin et al. · Vaccine
Open access |
5 Jan 2010 |
34 |
| 28 |
Pharmacokinetics of Macitentan in Caucasian and Japanese Subjects: The Influence of Ethnicity and Sex
Shirin Bruderer, Joanne K. Marjason, Patricia N. Sidharta et al. · Pharmacology
|
2013 |
34 |
| 29 |
Immune responses to a HSV-2 polynucleotide immunotherapy COR-1 in HSV-2 positive subjects: A randomized double blinded phase I/IIa trial
Janin Chandra, Wai-Ping Woo, J.L. Dutton et al. · PLoS ONE
Open access |
17 Dec 2019 |
32 |
| 30 |
Replication and Excretion of the Live Attenuated Tetravalent Dengue Vaccine CYD-TDV in a Flavivirus-Naive Adult Population: Assessment of Vaccine Viremia and Virus Shedding
Joseph Torresi, Peter Richmond, Leon G. Heron et al. · The Journal of Infectious Diseases
|
31 Aug 2017 |
32 |
| 31 |
Open-Label, Single-Dose, Parallel-Group Study in Healthy Volunteers To Determine the Drug-Drug Interaction Potential between KAE609 (Cipargamin) and Piperaquine
Daniel S. Stein, Jay Prakash Jain, Michael J. Kangas et al. · Antimicrobial Agents and Chemotherapy
Open access |
7 Apr 2015 |
31 |
| 32 |
RVT-1401, A Novel Anti-FcRn Monoclonal Antibody, Is Well Tolerated in Healthy Subjects and Reduces Plasma IgG Following Subcutaneous or Intravenous Administration (P5.2-079)
Jon W. Collins, Lori S. Jones, Michele Snyder et al. · Neurology
|
9 Apr 2019 |
30 |
| 33 |
Lot-to-lot consistency of a tetravalent dengue vaccine in healthy adults in Australia: A randomised study
Joseph Torresi, Leon G. Heron, Ming Qiao et al. · Vaccine
Open access |
13 Aug 2015 |
27 |
| 34 |
Efficacy and safety of methionine aminopeptidase 2 inhibition in type 2 diabetes: a randomised, placebo-controlled clinical trial
Joseph Proietto, Jaret L. Malloy, Dongliang Zhuang et al. · Diabetologia
Open access |
11 Jul 2018 |
20 |
| 35 |
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Coadministered Ruxolitinib and Artemether-Lumefantrine in Healthy Adults
M. Farouk Chughlay, Karen I. Barnes, Myriam El Gaaloul et al. · Antimicrobial Agents and Chemotherapy
Open access |
25 Oct 2021 |
16 |
| 36 |
Infectivity of Plasmodium falciparum in Malaria-Naive Individuals Is Related to Knob Expression and Cytoadherence of the Parasite
Danielle I. Stanisic et al. · Infection and Immunity
Open access |
6 Jul 2016 |
14 |
| 37 |
Thymine, adenine and lipoamino acid based gene delivery systems
Mariusz Skwarczyński, Zyta Maria Ziora, Daniel J. Coles et al. · Chemical Communications
|
2010 |
13 |
| 38 |
Fasting increases serum bilirubin levels in clinically normal, healthy males but not females: a retrospective study from phase I clinical trial participants
Paul Griffin, Suzanne L. Elliott, Kerry J. Manton · Journal of Clinical Pathology
|
4 Mar 2014 |
12 |
| 39 |
Pharmacokinetics and Tolerability of Almorexant in Japanese and Caucasian Healthy Male Subjects
Matthias Hoch, Petra Hoever, Federica Alessi et al. · Pharmacology
|
2011 |
7 |
| 40 |
Lipopeptides for the Fragment-Based Pharmaceutics Design
Zyta Maria Ziora, Norbert Wimmer, Roger R. C. New et al. · International Journal of Organic Chemistry
Open access |
2012 |
4 |
| 41 |
Concomitant or sequential administration of live attenuated Japanese encephalitis chimeric virus vaccine and yellow fever 17D vaccine: randomized double-blind phase II evaluation of safety and immunogenicity.
Peter Nasveld, Joanne K. Marjason, Sonya Bennett et al. · PubMed
Open access |
Nov 2010 |
4 |
| 42 |
A phase 1 evaluation of the pharmacokinetic/pharmacodynamic interaction of the antimalarial agents KAE609 and piperaquine (PPQ)
Daniel S. Stein, Jay Prakash Jain, Jason D. Lickliter et al. · Malaria Journal
Open access |
Sep 2014 |
1 |
| 43 |
Clinical and non-clinical exploration of Thinqure20 (a herbal composition) in treatment and prophylaxis of novel coronavirus and in other pathogens.
Milind Gharpure, Hrishikesh ranganekar, Pranjali Pradeep Dhawal et al. · Research Square
PreprintOpen access |
2 May 2022 |
1 |
| 44 |
Elarekibep, an inhaled Anticalin protein, targets IL-4Rα locally: first-in-human randomized phase 1 trials of a novel potential therapeutic class in asthma
Ingmar B. Bruns et al. · Respiratory Research
Open access |
19 Aug 2026 |
0 |
| 45 |
A Prospective clinical trial of RENOCHLOR (Sodium Copper Chlorophyllin complex) formulations as an add-on therapy for the Management of Chronic Renal Failure (CRF)
Milind Gharpure, Nikhil Varma, Ravindra Mote et al. · Research Square
PreprintOpen access |
21 Jun 2022 |
0 |
| 46 |
Clinical exploration of safety and efficacy of Polyherbal oil as a topical application in Diabetic non healing wounds and ulcers compared with Betadine10% ointment
Milind Gharpure, Nikhil Varma, Gopal Rao et al. · Research Square
PreprintOpen access |
7 Jun 2022 |
0 |
| 47 |
Safety, Tolerability, Pharmacokinetics, and Immunogenicity of a Human Monoclonal Antibody Targeting the G Glycoprotein of Henipaviruses in Healthy Adults: A Randomised, First-in-Human Phase 1 Study
Elliott Geoffrey Playford et al. · SSRN Electronic Journal
PreprintOpen access |
2019 |
0 |
| 48 |
414 A fitst-in-human study of BLZ-100 (tozuleristide) demonstrates tolerability and fluorescence contrast in skin cancer
Miko Yamada, Dennis Michael Miller, Melinda Lowe et al. · Journal of Investigative Dermatology
Open access |
19 Apr 2018 |
0 |
| 49 |
Molecular methods for quantification of P. Falciparum and gametocyte detection
Paul Griffin, Rebecca J. Rockett, Katharine R. Trenholme et al. · Pathology
|
2013 |
0 |