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g:Profiler: a web server for functional enrichment analysis and conversions of gene lists (2019 update)
Uku Raudvere, Liis Kolberg, Ivan Kuzmin et al. · Nucleic Acids Research
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30 Apr 2019 |
5,560 |
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Robust rank aggregation for gene list integration and meta-analysis
Raivo Kolde, Sven Laur, Priit Adler et al. · Bioinformatics
Open access |
12 Jan 2012 |
1,305 |
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g:Profiler—a web server for functional interpretation of gene lists (2011 update)
Jüri Reimand, T. V. Arak, Jaak Vilo · Nucleic Acids Research
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6 Jun 2011 |
527 |
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AIRE-Deficient Patients Harbor Unique High-Affinity Disease-Ameliorating Autoantibodies
Steffen Meyer et al. · Cell
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Jul 2016 |
299 |
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Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach
Anne K. Krug et al. · Archives of Toxicology
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20 Nov 2012 |
237 |
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Mining for coexpression across hundreds of datasets using novel rank aggregation and visualization methods
Priit Adler, Raivo Kolde, Meelis Kull et al. · Genome biology
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4 Dec 2009 |
153 |
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Design Principles of Concentration-Dependent Transcriptome Deviations in Drug-Exposed Differentiating Stem Cells
Tanja Waldmann, Eugen Rempel, Nina V. Balmer et al. · Chemical Research in Toxicology
Open access |
2 Jan 2014 |
110 |
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GOsummaries: an R Package for Visual Functional Annotation of Experimental Data
Raivo Kolde, Jaak Vilo · F1000Research
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18 Aug 2015 |
107 |
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Computational biology: deep learning
William Jones, Kaur Alasoo, Dmytro Fishman et al. · Emerging Topics in Life Sciences
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14 Nov 2017 |
103 |
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Translating genotype data of 44,000 biobank participants into clinical pharmacogenetic recommendations: challenges and solutions
Sulev Reisberg, Kristi Krebs, Maarja Lepamets et al. · Genetics in Medicine
Open access |
16 Oct 2018 |
99 |
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Epigenetic changes and disturbed neural development in a human embryonic stem cell-based model relating to the fetal valproate syndrome
Nina V. Balmer, Matthias K. Weng, Bastian Zimmer et al. · Human Molecular Genetics
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20 Jun 2012 |
99 |
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A Data Integration Approach to Mapping OCT4 Gene Regulatory Networks Operative in Embryonic Stem Cells and Embryonal Carcinoma Cells
Marc Jung, Hedi Peterson, Lukas Chávez et al. · PLoS ONE
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20 May 2010 |
89 |
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Comparing distributions of polygenic risk scores of type 2 diabetes and coronary heart disease within different populations
Sulev Reisberg, Tatjana Iljasenko, Kristi Läll et al. · PLoS ONE
Open access |
5 Jul 2017 |
85 |
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From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects
Nina V. Balmer, Stefanie Klima, Eugen Rempel et al. · Archives of Toxicology
Open access |
17 Jun 2014 |
78 |
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Characterization of the Phosphoinositide 3-Kinase-Dependent Transcriptome in Murine Embryonic Stem Cells: Identification of Novel Regulators of Pluripotency
Michael P. Storm, Benjamin Kumpfmueller, Belinda A.N. Thompson et al. · Stem Cells
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15 Jan 2009 |
72 |
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Melanocytes in the Skin – Comparative Whole Transcriptome Analysis of Main Skin Cell Types
Paula Reemann, Ene Reimann, Sten Ilmjärv et al. · PLoS ONE
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29 Dec 2014 |
67 |
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C-reactive protein upregulates the whole blood expression of CD59 - an integrative analysis
Kaido Lepik, Tarmo Annilo, Viktorija Kukuškina et al. · PLoS Computational Biology
Open access |
18 Sep 2017 |
64 |
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The metabolic analysis of psoriasis identifies the associated metabolites while providing computational models for the monitoring of the disease
Aigar Ottas, Dmytro Fishman, Tiia-Linda Okas et al. · Archives of Dermatological Research
Open access |
10 Jul 2017 |
62 |
| 19 |
Endometrial transcriptome analysis indicates superiority of natural over artificial cycles in recurrent implantation failure patients undergoing frozen embryo transfer
Signe Altmäe, Karin Tamm-Rosenstein, Francisco José Esteban et al. · Reproductive BioMedicine Online
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28 Mar 2016 |
58 |
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Signs of innate immune activation and premature immunosenescence in psoriasis patients
Liisi Šahmatova, Elena Sügis, Marina Šunina et al. · Scientific Reports
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2 Aug 2017 |
57 |
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Autoantibody Repertoire in APECED Patients Targets Two Distinct Subgroups of Proteins
Dmytro Fishman et al. · Frontiers in Immunology
Open access |
15 Aug 2017 |
51 |
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Identifying Cases of Type 2 Diabetes in Heterogeneous Data Sources: Strategy from the EMIF Project
Giuseppe Roberto et al. · PLoS ONE
Open access |
31 Aug 2016 |
51 |
| 23 |
Neuroglobin-Deficiency Exacerbates Hif1A and c-FOS Response, but Does Not Affect Neuronal Survival during Severe Hypoxia In Vivo
Christian Ansgar Hundahl, Hendrik Luuk, Sten Ilmjärv et al. · PLoS ONE
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2 Dec 2011 |
48 |
| 24 |
Blood serum metabolome of atopic dermatitis: Altered energy cycle and the markers of systemic inflammation
Aigar Ottas, Dmytro Fishman, Tiia-Linda Okas et al. · PLoS ONE
Open access |
27 Nov 2017 |
43 |
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Prediction of RNA Polymerase II recruitment, elongation and stalling from histone modification data
Yun Chen, Mette Jørgensen, Raivo Kolde et al. · BMC Genomics
Open access |
3 Nov 2011 |
39 |
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Three LIF-dependent signatures and gene clusters with atypical expression profiles, identified by transcriptome studies in mouse ES cells and early derivatives
Marina Trouillas, Claire Saucourt, Bertrand Guillotin et al. · BMC Genomics
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9 Feb 2009 |
37 |
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Comprehensive transcriptome analysis of mouse embryonic stem cell adipogenesis unravels new processes of adipocyte development
Nathalie Billon, Raivo Kolde, Jüri Reimand et al. · Genome biology
Open access |
3 Aug 2010 |
36 |
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Validating Fitbit Zip for monitoring physical activity of children in school: a cross-sectional study
Kerli Mooses, Marek Oja, Sulev Reisberg et al. · BMC Public Health
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11 Jul 2018 |
35 |
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Test systems of developmental toxicity: state-of-the art and future perspectives
Marcel Leist, Annette Ringwald, Raivo Kolde et al. · Archives of Toxicology
Open access |
4 Nov 2013 |
35 |
| 30 |
Multiplex analysis of 40 cytokines do not allow separation between endometriosis patients and controls
Tamara Knific, Dmytro Fishman, Andrej Vogler et al. · Scientific Reports
Open access |
13 Nov 2019 |
29 |
| 31 |
Prostaglandin D2 Receptor DP1 Antibodies Predict Vaccine-induced and Spontaneous Narcolepsy Type 1: Large-scale Study of Antibody Profiling
Helle Sadam, Arno Pihlak, Anri Kivil et al. · EBioMedicine
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2 Feb 2018 |
29 |
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Whole-genome expression analysis reveals genes associated with treatment response to escitalopram in major depression
Kristi Pettai, Lili A. Milani, Anu Tammiste et al. · European Neuropsychopharmacology
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23 Jul 2016 |
28 |
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Gene Expression Signatures Defining Fundamental Biological Processes in Pluripotent, Early, and Late Differentiated Embryonic Stem Cells
John Antonydas Gaspar, Michael Xavier Doss, Johannes Winkler et al. · Stem Cells and Development
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15 Mar 2012 |
23 |
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Endometrial cancer diagnostic and prognostic algorithms based on proteomics, metabolomics, and clinical data: a systematic review
Andrea Romano, Tea Lanišnik Rižner, Henrica M.J. Werner et al. · Frontiers in Oncology
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6 Apr 2023 |
21 |
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Fast approximate hierarchical clustering using similarity heuristics
Meelis Kull, Jaak Vilo · BioData Mining
Open access |
22 Sep 2008 |
21 |
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Development and external validation of prediction models for adverse health outcomes in rheumatoid arthritis: A multinational real-world cohort analysis
Cynthia Barcelon Yang et al. · Seminars in Arthritis and Rheumatism
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14 Jun 2022 |
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Trajectories: a framework for detecting temporal clinical event sequences from health data standardized to the Observational Medical Outcomes Partnership (OMOP) Common Data Model
Kadri Künnapuu, Solomon Ioannou, Kadri Ligi et al. · JAMIA Open
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7 Jan 2022 |
17 |
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PGC-1α Signaling Increases GABA(A) Receptor Subunit α2 Expression, GABAergic Neurotransmission and Anxiety-Like Behavior in Mice
Taavi Vanaveski, Svetlana M. Molchanova, Dan Duc Pham et al. · Frontiers in Molecular Neuroscience
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Feb 2021 |
17 |
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Fingerprinting of neurotoxic compounds using a mouse embryonic stem cell dual luminescence reporter assay
Marilena Colaianna, Sten Ilmjärv, Hedi Peterson et al. · Archives of Toxicology
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25 Mar 2016 |
16 |
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Qualitative modeling identifies IL-11 as a novel regulator in maintaining self-renewal in human pluripotent stem cells
Hedi Peterson, Raed Abu Dawud, Abhishek Dinkarnath Garg et al. · Frontiers in Physiology
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2013 |
15 |
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Estimating differential expression from multiple indicators
Sten Ilmjärv, Christian Ansgar Hundahl, Riin Reimets et al. · Nucleic Acids Research
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27 Feb 2014 |
14 |
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Ranking Genes by Their Co‐expression to Subsets of Pathway Members
Priit Adler, Hedi Peterson, Phaedra Agius et al. · Annals of the New York Academy of Sciences
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Mar 2009 |
11 |
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Prevaccination Prevalence of Type-Specific Human Papillomavirus Infection by Grade of Cervical Cytology in Estonia
Anneli Uusküla, Marek Oja, Sirli Tamm et al. · JAMA Network Open
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6 Feb 2023 |
10 |
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VisHiC--hierarchical functional enrichment analysis of microarray data
D. Krushevskaya, Hedi Peterson, Jüri Reimand et al. · Nucleic Acids Research
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29 May 2009 |
10 |
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An exploratory phenome wide association study linking asthma and liver disease genetic variants to electronic health records from the Estonian Biobank
Glen James, Sulev Reisberg, Kaido Lepik et al. · PLoS ONE
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12 Apr 2019 |
9 |
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A field-wide assessment of differential expression profiling by high-throughput sequencing reveals widespread bias
Taavi Päll, Hannes Luidalepp, Tanel Tenson et al. · PLoS Biology
Open access |
2 Mar 2023 |
7 |
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PAWER: protein array web exploreR
Dmytro Fishman, Ivan Kuzmin, Priit Adler et al. · BMC Bioinformatics
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17 Sep 2020 |
7 |
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Global transcriptomic analysis of murine embryonic stem cell‐derived brachyury+ (T) cells
Michael Xavier Doss, Vilas Wagh, Herbert Schulz et al. · Genes to Cells
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25 Feb 2010 |
7 |
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funcExplorer: a tool for fast data-driven functional characterisation of high-throughput expression data
Liis Kolberg, Ivan Kuzmin, Priit Adler et al. · BMC Genomics
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14 Nov 2018 |
6 |
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Leveraging biobank-scale rare and common variant analyses to identify ASPHD1 as the main driver of reproductive traits in the 16p11.2 locus
Katrin Männik et al. · bioRxiv (Cold Spring Harbor Laboratory)
PreprintOpen access |
26 Jul 2019 |
5 |