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Most cited papers from Research & Development Corporation

What are the most cited papers from Research & Development Corporation?

The most cited paper from Research & Development Corporation is "A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells" (Roy A. Black, Charles T. Rauch, Carl J. Kozlosky et al., 1997), with 3,168 citations. Next come "RANK is essential for osteoclast and lymph node development" (1,506) and "Cloning of a T Cell Growth Factor that Interacts with the β Chain of the Interleukin-2 Receptor" (1,432).

Showing 50 of 60 papers. Every paper with more than 319 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells Roy A. Black, Charles T. Rauch, Carl J. Kozlosky et al. · Nature Feb 1997 3,168
2 RANK is essential for osteoclast and lymph node development William C. Dougall, Moira B. Glaccum, K Charrier et al. · Genes & Development Open access 15 Sep 1999 1,506
3 Cloning of a T Cell Growth Factor that Interacts with the β Chain of the Interleukin-2 Receptor Kenneth H. Grabstein, June Eisenman, Kurt D. Shanebeck et al. · Science 13 May 1994 1,432
4 Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas Thomas B. Brunner, Rona J. Mogil, Drake LaFace et al. · Nature Open access Feb 1995 1,342
5 ULBPs, Novel MHC Class I–Related Molecules, Bind to CMV Glycoprotein UL16 and Stimulate NK Cytotoxicity through the NKG2D Receptor David J. Cosman, Jürgen Müllberg, Claire L. Sutherland et al. · Immunity Open access Feb 2001 1,218
6 Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified. Eugene Maraskovsky, Kenneth Brasel, Mark Teepe et al. · The Journal of Experimental Medicine Open access Nov 1996 1,134
7 Human IL-17: a novel cytokine derived from T cells Zemin Yao, Sally L. Painter, William C. Fanslow et al. · The Journal of Immunology Dec 1995 1,033
8 Molecular and biological characterization of a murine ligand for CD40 Richard J. Armitage, William C. Fanslow, Laura D. Strockbine et al. · Nature May 1992 1,031
9 Utilization of the beta and gamma chains of the IL‐2 receptor by the novel cytokine IL‐15. Judith G. Giri, Minoo Ahdieh, June Eisenman et al. · The EMBO Journal Open access Jun 1994 998
10 Interleukin-1 Type II Receptor: A Decoy Target for IL-1 That Is Regulated by IL-4 Francesco Colotta, Fabio Re, Marta Muzio et al. · Science 23 Jul 1993 988
11 Identification of a ligand for the c-kit proto-oncogene Douglas E. Williams, June Eisenman, Allison M. Baird et al. · Cell Oct 1990 957
12 Fas ligand mediates activation-induced cell death in human T lymphocytes. Mark R. Alderson, Teresa W. Tough, Terri Davis‐Smith et al. · The Journal of Experimental Medicine Open access 1995 957
13 The IL-6 Signal Transducer, gp130: an Pncostatin M Receptor and Affinity Converter for the LIF Receptor David P. Gearing, Michael R. Comeau, Della J. Friend et al. · Science 13 Mar 1992 900
14 Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells Hilary J. McKenna, Kim L. Stocking, Robert E. Miller et al. · Blood Jun 2000 895
15 Soluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonists. K M Mohler, Dauphine Torrance, Carole Smith et al. · The Journal of Immunology Aug 1993 838
16 CD40 Ligand Gene Defects Responsible for X-Linked Hyper-IgM Syndrome R.Cutler Allen, Richard J. Armitage, Mary Ellen Conley et al. · Science 12 Feb 1993 836
17 TNF Receptor-Deficient Mice Reveal Divergent Roles for p55 and p75 in Several Models of Inflammation Jacques J. Peschon, Dauphine Torrance, Kim L. Stocking et al. · The Journal of Immunology Open access 1998 715
18 A Novel Immunoglobulin Superfamily Receptor for Cellular and Viral MHC Class I Molecules David J. Cosman, Neil A. Fanger, Luís Borges et al. · Immunity Open access Aug 1997 694
19 A novel IL‐1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types. Catherine J. McMahan, Jennifer L. Slack, Bruce Mosley et al. · The EMBO Journal Open access Oct 1991 684
20 Intracellular Regulation of TRAIL-Induced Apoptosis in Human Melanoma Cells Thomas S. Griffith, Wilson Chin, Glenn C. Jackson et al. · The Journal of Immunology Open access Sep 1998 671
21 Interleukin-1 Mitogenic Activity for Fibroblasts and Smooth Muscle Cells Is Due to PDGF-AA Elaine W. Raines, Steven Dower, Russell Ross · Science 20 Jan 1989 648
22 Identification and cloning of a novel IL‐15 binding protein that is structurally related to the alpha chain of the IL‐2 receptor. Judith G. Giri, Satoru Kumaki, Minoo Ahdieh et al. · The EMBO Journal Open access Aug 1995 647
23 Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery Mark Kennedy, Dauphine Torrance, Kathleen S. Picha et al. · The Journal of Immunology Oct 1992 622
24 Interleukin 1 signaling occurs exclusively via the type I receptor. John E. Sims, Margit A. Gayle, Jennifer L. Slack et al. · Proceedings of the National Academy of Sciences Open access Jul 1993 611
25 CD40 expression by human monocytes: regulation by cytokines and activation of monocytes by the ligand for CD40. Mark R. Alderson, Richard J. Armitage, Teresa W. Tough et al. · The Journal of Experimental Medicine Open access Aug 1993 587
26 A Novel Model of Inflammatory Bowel Disease: Mice Deficient for the Multiple Drug Resistance Gene, mdr1a, Spontaneously Develop Colitis Chetan M Panwala, Jon C. Jones, Joanne L. Viney · The Journal of Immunology Open access Nov 1998 571
27 Humoral immune responses in CD40 ligand-deficient mice. Blair R. Renshaw, William C. Fanslow, Richard J. Armitage et al. · The Journal of Experimental Medicine Open access Nov 1994 540
28 Fas transduces activation signals in normal human T lymphocytes. Mark R. Alderson, Richard J. Armitage, Eugene Maraskovsky et al. · The Journal of Experimental Medicine Open access Dec 1993 524
29 Growth of a cloned helper T cell line induced by a monoclonal antibody specific for the antigen receptor: interleukin 1 is required for the expression of receptors for interleukin 2. Jonathan Kaye, Steven A. Gillis, S B Mizel et al. · The Journal of Immunology Sep 1984 524
30 An early India-Asia contact: Paleomagnetic constraints from Ninetyeast Ridge, ODP Leg 121 Chris T. Klootwijk, J. S. Gee, John W. Peirce et al. · Geology 1992 512
31 Functional Analysis of the Domain Structure of Tumor Necrosis Factor-α Converting Enzyme Pranhitha Reddy, Jennifer L. Slack, Raymond Davis et al. · Journal of Biological Chemistry Open access May 2000 503
32 CD4+ T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice. Disease development is prevented by cotransfer of purified CD4+ T cells. Philip Morrissey, K Charrier, Steve Braddy et al. · The Journal of Experimental Medicine Open access Jul 1993 476
33 Tumor necrosis factor ligand superfamily: involvement in the pathology of malignant lymphomas HJ Gruss, Steven Dower · Blood 15 Jun 1995 458
34 TRAIL: a molecule with multiple receptors and control mechanisms Thomas S. Griffith, David H. Lynch · Current Opinion in Immunology Review Oct 1998 455
35 Developmental pathways of dendritic cells in vivo: distinct function, phenotype, and localization of dendritic cell subsets in FLT3 ligand-treated mice Bali Pulendran, Jai Lingappa, Mark Kennedy et al. · The Journal of Immunology Sep 1997 446
36 IL-15 has stimulatory activity for the induction of B cell proliferation and differentiation. R J Armitage, Brian M. Macduff, June Eisenman et al. · The Journal of Immunology 1995 443
37 Use of defined TLR ligands as adjuvants within human vaccines Malcolm S. Duthie, Hillarie Plessner Windish, Christopher B. Fox et al. · Immunological Reviews ReviewOpen access 28 Dec 2010 442
38 Generation of murine dendritic cells from flt3-ligand–supplemented bone marrow cultures Kenneth Brasel, Thibaut De Smedt, Jeffery L. Smith et al. · Blood Nov 2000 439
39 Activated T cells induce interleukin‐12 production by monocytes via CD40‐CD40 ligand interaction Uno Shu, Mamoru Kiniwa, Chang You Wu et al. · European Journal of Immunology Apr 1995 419
40 Human Dendritic Cells Mediate Cellular Apoptosis via Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (Trail) Neil A. Fanger, Charles R. Maliszewski, Ken Schooley et al. · The Journal of Experimental Medicine Open access 18 Oct 1999 413
41 Flt3-Ligand and Granulocyte Colony-Stimulating Factor Mobilize Distinct Human Dendritic Cell Subsets In Vivo Bali Pulendran, Jacques Banchereau, Susan B. Burkeholder et al. · The Journal of Immunology Jul 2000 411
42 Efficacy of soluble IL-4 receptor for the treatment of adults with asthma Larry Borish, Harold S. Nelson, Jonathan Corren et al. · Journal of Allergy and Clinical Immunology Open access Jun 2001 411
43 Recombinant human CD40 ligand stimulates B cell proliferation and immunoglobulin E secretion. Melanie K. Spriggs, Richard J. Armitage, Laura D. Strockbine et al. · The Journal of Experimental Medicine Open access Dec 1992 403
44 A Lymphotoxin-β-Specific Receptor Paul D. Crowe, Todd L. VanArsdale, Barbara N. Walter et al. · Science 29 Apr 1994 401
45 In vivo generation of human dendritic cell subsets by Flt3 ligand Eugene Maraskovsky, Elizabeth Daro, Eileen R. Roux et al. · Blood Aug 2000 399
46 Safety and Efficacy of a Soluble P75 Tumor Necrosis Factor Receptor (Enbrel, Etanercept) in Patients With Advanced Heart Failure Anita Deswal, Biykem Bozkurt, Yukihiro Seta et al. · Circulation 29 Jun 1999 396
47 Results of Targeted Anti–Tumor Necrosis Factor Therapy With Etanercept (ENBREL) in Patients With Advanced Heart Failure Biykem Bozkurt, Guillermo Torre‐Amione, Marshelle Smith Warren et al. · Circulation 27 Feb 2001 389
48 Phenotypic and functional characterization of mice that lack the type I receptor for IL-1 Moira B. Glaccum, Kim L. Stocking, K Charrier et al. · The Journal of Immunology Oct 1997 387
49 Role of Lymphotoxin and the Type I TNF Receptor in the Formation of Germinal Centers Mitsuru Matsumoto, Sanjeev Mariathasan, Moon H. Nahm et al. · Science Mar 1996 382
50 Anti-cytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes. Fred D. Finkelman, Kathleen B. Madden, Suzanne C. Morris et al. · The Journal of Immunology Aug 1993 368

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.