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Most cited papers from Rosetta Stone (United States)

What are the most cited papers from Rosetta Stone (United States)?

The most cited paper from Rosetta Stone (United States) is "Gene expression profiling predicts clinical outcome of breast cancer" (Laura van ‘t Veer, Hongyue A. Dai, Marc J. van de Vijver et al., 2002), with 9,661 citations. Next come "A Gene-Expression Signature as a Predictor of Survival in Breast Cancer" (6,562) and "Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs" (4,816).

Showing 50 of 60 papers. Every paper with more than 390 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Gene expression profiling predicts clinical outcome of breast cancer Laura van ‘t Veer, Hongyue A. Dai, Marc J. van de Vijver et al. · Nature Open access 2002 9,661
2 A Gene-Expression Signature as a Predictor of Survival in Breast Cancer Marc J. van de Vijver et al. · New England Journal of Medicine Open access 18 Dec 2002 6,562
3 Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs Lee P. Lim, Nelson C. Lau, Philip W. Garrett-Engele et al. · Nature 30 Jan 2005 4,816
4 Functional profiling of the Saccharomyces cerevisiae genome Guri N. Giaever et al. · Nature 25 Jul 2002 4,557
5 Functional Characterization of the S. cerevisiae Genome by Gene Deletion and Parallel Analysis Elizabeth A. Winzeler et al. · Science 6 Aug 1999 4,050
6 MicroRNA Targeting Specificity in Mammals: Determinants beyond Seed Pairing Andrew W. Grimson, Kyle Kai‐How Farh, Wendy K. Johnston et al. · Molecular Cell Open access Jul 2007 3,853
7 A microRNA component of the p53 tumour suppressor network Lin He, Xingyue He, Lee P. Lim et al. · Nature Open access 6 Jun 2007 2,713
8 Integration of biological networks and gene expression data using Cytoscape Melissa Cline et al. · Nature Protocols Open access 27 Sep 2007 2,601
9 Functional Discovery via a Compendium of Expression Profiles Timothy R. Hughes et al. · Cell Open access Jul 2000 2,581
10 Expression profiling reveals off-target gene regulation by RNAi Aimee L. Jackson, Steven R. Bartz, Janell M. Schelter et al. · Nature Biotechnology 16 May 2003 2,404
11 Hundreds of variants clustered in genomic loci and biological pathways affect human height Hana Lango Allen et al. · Nature Open access293 authors 29 Sep 2010 2,063
12 Rosetta3 Andrew Leaver‐Fay et al. · Methods in enzymology on CD-ROM/Methods in enzymology Book chapterOpen access 26 Dec 2010 2,057
13 Defining clusters from a hierarchical cluster tree: the Dynamic Tree Cut package for R Peter Langfelder, Bin Zhang, Steve Horvath · Bioinformatics 16 Nov 2007 2,045
14 CTLA-4 and PD-1 Receptors Inhibit T-Cell Activation by Distinct Mechanisms Richard V. Parry, Jens Marcus Chemnitz, Kenneth A. Frauwirth et al. · Molecular and Cellular Biology Open access 14 Oct 2005 1,942
15 Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis Christopher Lock, G Hermans, Rosetta Pedotti et al. · Nature Medicine May 2002 1,681
16 Genetics of gene expression surveyed in maize, mouse and man Eric E. Schadt, Stephanie A. Monks, Thomas A. Drake et al. · Nature Mar 2003 1,547
17 The Widespread Impact of Mammalian MicroRNAs on mRNA Repression and Evolution Kyle Kai‐How Farh, Andrew W. Grimson, Calvin Jan et al. · Science 24 Nov 2005 1,509
18 Genome-Wide Survey of Human Alternative Pre-mRNA Splicing with Exon Junction Microarrays Jason Michael Johnson, John C. Castle, Philip W. Garrett-Engele et al. · Science 18 Dec 2003 1,427
19 Common variants at 30 loci contribute to polygenic dyslipidemia Sekar Kathiresan et al. · Nature Genetics Open access 7 Dec 2008 1,383
20 Genetics of gene expression and its effect on disease Valur Emilsson et al. · Nature Mar 2008 1,351
21 Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer Timothy R. Hughes et al. · Nature Biotechnology Apr 2001 1,301
22 The Collaborative Cross, a community resource for the genetic analysis of complex traits Gary A. Churchill et al. · Nature Genetics Open access113 authors 28 Oct 2004 1,198
23 An integrative genomics approach to infer causal associations between gene expression and disease Eric E. Schadt et al. · Nature Genetics Open access 19 Jun 2005 1,091
24 A large-scale RNAi screen in human cells identifies new components of the p53 pathway Katrien Berns, E. Marielle Hijmans, Jasper Mullenders et al. · Nature Cell Biology Open access 24 Mar 2004 1,077
25 Widespread siRNA “off-target” transcript silencing mediated by seed region sequence complementarity Aimee L. Jackson, Julja Burchard, Janell M. Schelter et al. · RNA Open access 8 May 2006 971
26 Tissue-specific expression and regulation of sexually dimorphic genes in mice Xia Yang, Eric E. Schadt, Susanna Sue-Ming Wang et al. · Genome Research Open access 6 Jul 2006 945
27 Mapping the Genetic Architecture of Gene Expression in Human Liver Eric E. Schadt et al. · PLoS Biology Open access 29 Apr 2008 934
28 The colorectal microRNAome Jordan M. Cummins, Yiping He, Rebecca J. Leary et al. · Proceedings of the National Academy of Sciences 27 Feb 2006 929
29 Variations in DNA elucidate molecular networks that cause disease Yanqing Chen et al. · Nature Open access Mar 2008 909
30 MicroRNA 21 Promotes Glioma Invasion by Targeting Matrix Metalloproteinase Regulators Galina Gabriely, Thomas Würdinger, Santosh Kesari et al. · Molecular and Cellular Biology Open access Jul 2008 893
31 Signaling and Circuitry of Multiple MAPK Pathways Revealed by a Matrix of Global Gene Expression Profiles Christopher J. Roberts, Bryce Nelson, Matthew John Marton et al. · Science 4 Feb 2000 872
32 Position-specific chemical modification of siRNAs reduces “off-target” transcript silencing Aimee L. Jackson, Julja Burchard, Devin Leake et al. · RNA Open access 8 May 2006 794
33 Integrated Genomic and Proteomic Analyses of Gene Expression in Mammalian Cells Qiang Tian, Serguei Stepaniants, Mao Mao et al. · Molecular & Cellular Proteomics Open access 6 Jul 2004 790
34 Transcriptional Profiling Shows that Gcn4p Is a Master Regulator of Gene Expression during Amino Acid Starvation in Yeast Krishnamurthy Natarajan, Michael R. Meyer, Belinda M. Jackson et al. · Molecular and Cellular Biology Open access Jul 2001 770
35 A resource for large-scale RNA-interference-based screens in mammals Patrick J. Paddison, José M. Silva, Douglas S. Conklin et al. · Nature Cell Biology 24 Mar 2004 703
36 Drug target validation and identification of secondary drug target effects using DNA microarrays Matthew John Marton, Joseph L. DeRisi, Holly A. Bennett et al. · Nature Medicine Nov 1998 646
37 Second-generation shRNA libraries covering the mouse and human genomes José M. Silva, Mamie Z. Li, Ken C. N. Chang et al. · Nature Genetics 2 Oct 2005 626
38 CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris Judith R. Abrams, Mark Lebwohl, Cynthia A. Guzzo et al. · Journal of Clinical Investigation Open access May 1999 602
39 A Global Profile of Germline Gene Expression in C. elegans V Reinke, Harold E. Smith, Jeremy Nance et al. · Molecular Cell Open access Sep 2000 595
40 Gene expression changes associated with progression and response in chronic myeloid leukemia Jerald P. Radich, Hongyue A. Dai, Mao Mao et al. · Proceedings of the National Academy of Sciences Open access 13 Feb 2006 594
41 Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks Jun Zhu, Bin Zhang, Erin N. Smith et al. · Nature Genetics Open access 15 Jun 2008 590
42 Genomic profiling of drug sensitivities via induced haploinsufficiency Guri N. Giaever, Daniel D. Shoemaker, Ted Jones et al. · Nature Genetics Mar 1999 586
43 Transcripts Targeted by the MicroRNA-16 Family Cooperatively Regulate Cell Cycle Progression Peter S. Linsley, Janell M. Schelter, Julja Burchard et al. · Molecular and Cellular Biology Open access 22 Jan 2007 562
44 MicroRNAs in the miR-106b Family Regulate p21/CDKN1A and Promote Cell Cycle Progression Irena Lambrova Ivanovska, Alexey S. Ball, Robert L. Diaz et al. · Molecular and Cellular Biology Open access 22 Jan 2008 560
45 Overexpression of a kinase‐inactive ATR protein causes sensitivity to DNA‐damaging agents and defects in cell cycle checkpoints William A. Cliby, Christopher J. Roberts, Karlene A. Cimprich et al. · The EMBO Journal Open access 1998 536
46 A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart Auinash Kalsotra, Xinshu Grace Xiao, Amanda J. Ward et al. · Proceedings of the National Academy of Sciences Open access 15 Dec 2008 523
47 Integrating Genetic and Network Analysis to Characterize Genes Related to Mouse Weight Anatole Ghazalpour, Sudheer Doss, Bin Zhang et al. · PLoS Genetics Open access 15 Aug 2006 504
48 Widespread aneuploidy revealed by DNA microarray expression profiling Timothy R. Hughes, Chris J. Roberts, Hongyue A. Dai et al. · Nature Genetics Jul 2000 497
49 Glyoxalase 1 and glutathione reductase 1 regulate anxiety in mice Iiris Hovatta, Richard S. Tennant, Robert Helton et al. · Nature 23 Oct 2005 493
50 Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2 Juan I. Young, Eugene P. Hong, John C. Castle et al. · Proceedings of the National Academy of Sciences Open access 26 Oct 2005 489

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.