| 1 |
Antibodies and venom peptides: new modalities for ion channels
Heike Wulff, Palle Christophersen, Paul A. Colussi et al. · Nature Reviews Drug Discovery
ReviewOpen access |
6 Feb 2019 |
191 |
| 2 |
Pharmacology of Small- and Intermediate-Conductance Calcium-Activated Potassium Channels
Brandon M. Brown, Heesung Shim, Palle Christophersen et al. · The Annual Review of Pharmacology and Toxicology
ReviewOpen access |
23 Jul 2019 |
117 |
| 3 |
A study of subunit selectivity, mechanism and site of action of the delta selective compound 2 ( DS2 ) at human recombinant and rodent native GABAA receptors
ML Jensen, Keith A. Wafford, AR Brown et al. · British Journal of Pharmacology
Open access |
12 Oct 2012 |
84 |
| 4 |
Subcellular expression and neuroprotective effects of SK channels in human dopaminergic neurons
Amalia M. Dolga, Anderson de Andrade, Lilja Meissner et al. · Cell Death and Disease
Open access |
16 Jan 2014 |
77 |
| 5 |
Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state
Alessandro Maria Villa et al. · Theranostics
Open access |
2018 |
68 |
| 6 |
Potassium channel expression and function in microglia: Plasticity and possible species variations
Hai Minh Nguyen, Linda V. Blomster, Palle Christophersen et al. · Channels
Open access |
Mar 2017 |
61 |
| 7 |
Pharmacological gating modulation of small- and intermediate-conductance Ca2+-activated K+channels (KCa2.x and KCa3.1)
Palle Christophersen, Heike Wulff · Channels
Open access |
28 Jul 2015 |
61 |
| 8 |
Molecular Recognition of the Neurotransmitter Acetylcholine by an Acetylcholine Binding Protein Reveals Determinants of Binding to Nicotinic Acetylcholine Receptors
Jeppe A. Olsen, Thomas Balle, Michael Gajhede et al. · PLoS ONE
Open access |
17 Mar 2014 |
47 |
| 9 |
GABAA Receptor α Subunits Differentially Contribute to Diazepam Tolerance after Chronic Treatment
Christiaan H. Vinkers, Ruud van Oorschot, Elsebet Østergaard Nielsen et al. · PLoS ONE
Open access |
13 Aug 2012 |
47 |
| 10 |
A pharmacological assessment of agonists and modulators at α4β2γ2 and α4β2δ GABA A receptors: The challenge in comparing apples with oranges
Philip Kiær Ahring, Line Haunstrup Bang, Marianne Lerbech Jensen et al. · Pharmacological Research
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10 May 2016 |
44 |
| 11 |
Structural and Functional Studies of the Modulator NS9283 Reveal Agonist-like Mechanism of Action at α4β2 Nicotinic Acetylcholine Receptors
Jeppe A. Olsen, Philip Kiær Ahring, Jette Sandholm Kastrup et al. · Journal of Biological Chemistry
Open access |
Jul 2014 |
43 |
| 12 |
Kv7 channels as targets for anti-epileptic and psychiatric drug-development
Morten Grunnet, Dorte Strøbæk, Charlotte Ørsted Hougaard et al. · European Journal of Pharmacology
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20 Jan 2014 |
43 |
| 13 |
Two Distinct Allosteric Binding Sites at α4β2 Nicotinic Acetylcholine Receptors Revealed by NS206 and NS9283 Give Unique Insights to Binding Activity-associated Linkage at Cys-loop Receptors
Jeppe A. Olsen, Jette Sandholm Kastrup, Dan Peters et al. · Journal of Biological Chemistry
Open access |
30 Oct 2013 |
42 |
| 14 |
Randomized controlled trial of Tesomet for weight loss in hypothalamic obesity
Kim Huynh, Marianne Klose, Kim Krogsgaard et al. · European Journal of Endocrinology
Open access |
16 Mar 2022 |
40 |
| 15 |
GABAA α5 subunit-containing receptors do not contribute to reversal of inflammatory-induced spinal sensitization as indicated by the unique selectivity profile of the GABAA receptor allosteric modulator NS16085
Ángel García de Lucas, Philip Kiær Ahring, Janus S. Larsen et al. · Biochemical Pharmacology
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25 Dec 2014 |
33 |
| 16 |
Orismilast in moderate-to-severe psoriasis: Efficacy and safety from a 16-week, randomized, double-blinded, placebo-controlled, dose-finding, and phase 2b trial (IASOS)
Richard Bruce Warren, Lars Einar French, Andrew Blauvelt et al. · Journal of the American Academy of Dermatology
Open access |
10 Nov 2023 |
30 |
| 17 |
NS383 Selectively Inhibits Acid‐Sensing Ion Channels Containing 1a and 3 Subunits to Reverse Inflammatory and Neuropathic Hyperalgesia in Rats
Gordon A. Munro, Jeppe K. Christensen, Helle K. Erichsen et al. · CNS Neuroscience & Therapeutics
Open access |
10 Dec 2015 |
28 |
| 18 |
The Delta-Subunit Selective GABAA Receptor Modulator, DS2, Improves Stroke Recovery via an Anti-inflammatory Mechanism
Silke Neumann, Lily Boothman-Burrell, Emma K. Gowing et al. · Frontiers in Neuroscience
Open access |
29 Oct 2019 |
27 |
| 19 |
Distinct neurodevelopmental and epileptic phenotypes associated with gain- and loss-of-function GABRB2 variants
Nazanin A. Mohammadi et al. · EBioMedicine
Open access |
11 Jul 2024 |
25 |
| 20 |
The effect of an integrated multidisciplinary rehabilitation programme for patients with chronic low back pain: Long-term follow up of a randomised controlled trial
Anne Schmidt, Trine Bay Laurberg, Line Thorndal Moll et al. · Clinical Rehabilitation
Open access |
11 Oct 2020 |
24 |
| 21 |
Acetylcholine-Binding Protein Engineered to Mimic the α4-α4 Binding Pocket in α4β2 Nicotinic Acetylcholine Receptors Reveals Interface Specific Interactions Important for Binding and Activity
Azadeh Shahsavar, Philip Kiær Ahring, Jeppe A. Olsen et al. · Molecular Pharmacology
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16 Jul 2015 |
24 |
| 22 |
Quantification of the functional expression of the Ca2+-activated K+channel KCa3.1 on microglia from adult human neocortical tissue
Linda V. Blomster, Dorte Strøbæk, Charlotte Ørsted Hougaard et al. · Glia
Open access |
29 Jul 2016 |
23 |
| 23 |
Engineered α4β2 nicotinic acetylcholine receptors as models for measuring agonist binding and effect at the orthosteric low-affinity α4–α4 interface
Philip Kiær Ahring, Jeppe A. Olsen, Elsebet Østergaard Nielsen et al. · Neuropharmacology
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14 Jan 2015 |
23 |
| 24 |
Pharmacological Profiling of KATP Channel Modulators: An Outlook for New Treatment Opportunities for Migraine
Tino Dyhring, Inger Jansen‐Olesen, Palle Christophersen et al. · Pharmaceuticals
Open access |
Feb 2023 |
21 |
| 25 |
Functional connectivity of spoken language processing in early-stage Parkinson’s disease: An MEG study
Rasha Hyder, Mads Jensen, Andreas Højlund et al. · NeuroImage Clinical
Open access |
2021 |
21 |
| 26 |
Delineation of the functional properties and the mechanism of action of TMPPAA, an allosteric agonist and positive allosteric modulator of 5-HT3 receptors
Agnes Gasiorek, Sarah M. Trattnig, Philip Kiær Ahring et al. · Biochemical Pharmacology
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13 Apr 2016 |
20 |
| 27 |
The effect of an integrated multidisciplinary rehabilitation programme alternating inpatient interventions with home-based activities for patients with chronic low back pain: a randomized controlled trial
Anne Schmidt, Berit Schiøttz‐Christensen, Nadine Elizabeth Foster et al. · Clinical Rehabilitation
Open access |
8 Jan 2020 |
18 |
| 28 |
Attenuation of nicotine taking and seeking in rats by the stoichiometry-selective alpha4beta2 nicotinic acetylcholine receptor positive allosteric modulator NS9283
John J. Maurer, Karin Sandager‐Nielsen, Heath D. Schmidt · Psychopharmacology
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14 Nov 2016 |
18 |
| 29 |
Understanding paralogous epilepsy–associated GABA A receptor variants: Clinical implications, mechanisms, and potential pitfalls
Anthony Sze Hon Kan, Ali Saad Kusay, Nazanin A. Mohammadi et al. · Proceedings of the National Academy of Sciences
Open access |
6 Dec 2024 |
17 |
| 30 |
Expression of α3β2β4 nicotinic acetylcholine receptors by rat adrenal chromaffin cells determined using novel conopeptide antagonists
Arik J. Hone, Lola Rueda‐Ruzafa, Thomas J. Gordon et al. · Journal of Neurochemistry
Open access |
22 Jan 2020 |
16 |
| 31 |
Biophysical and pharmacological characterization of α6-containing nicotinic acetylcholine receptors expressed in HEK293 cells
Andreas Rasmussen, Dorte Strøbæk, Tino Dyhring et al. · Brain Research
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21 Oct 2013 |
15 |
| 32 |
STN‐DBS affects language processing differentially in Parkinson's disease: Multiple‐case MEG study
Rasha Hyder, Andreas Højlund, Mads Jensen et al. · Acta Neurologica Scandinavica
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7 May 2021 |
11 |
| 33 |
Recent developments in ion channel pharmacology
Heike Wulff, Palle Christophersen · Channels
Open access |
2 Nov 2015 |
11 |
| 34 |
Four phase 1 trials to evaluate the safety and pharmacokinetic profile of single and repeated dosing of SCO‐101 in adult male and female volunteers
Troels K. Bergmann, Tore Bjerregaard Stage, Jan Stenvang et al. · Basic & Clinical Pharmacology & Toxicology
Open access |
6 Jul 2020 |
10 |
| 35 |
Critical Pedagogy and Children’s Engagement with Climate Change
Üzeyir Tireli, Jens Christian Jacobsen · Journal of School Administration Research and Development
Open access |
21 Apr 2023 |
8 |
| 36 |
The CFRP primary structure of the MIRI instrument onboard the James Webb Space Telescope
Niels Christian Jessen, Hans Ulrik Nørgaard-Nielsen, Tim Stevenson et al. · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
Conference paper |
29 Sep 2004 |
8 |
| 37 |
Immunogenicity and safety of a group B Streptococcus vaccine (GBS-AlpN) in pregnant women and their infants: a phase 2, multicentre, observer-blind, randomised, placebo-controlled study
Paul Trafford Heath et al. · The Lancet Infectious Diseases
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9 Dec 2025 |
7 |
| 38 |
An Integrated Multidisciplinary Rehabilitation Program Experienced by Patients with Chronic Low Back Pain
Julie Bøgdal, Anne Schmidt, Kirsten Østergaard Nielsen et al. · Clinical Medicine & Research
Open access |
Dec 2021 |
7 |
| 39 |
Anti-Tremor Action of Subtype Selective Positive Allosteric Modulators of GABAA Receptors in a Rat Model of Essential Tremors
Dipak Vasantrao Amrutkar, Tino Dyhring, Thomas A. Jacobsen et al. · The Cerebellum
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27 Jan 2020 |
7 |
| 40 |
Characterization of AN317, a novel selective agonist of α6β2-containing nicotinic acetylcholine receptors
Karin Sandager‐Nielsen, Philip Kiær Ahring, Jessica L. Klein et al. · Biochemical Pharmacology
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27 Dec 2019 |
7 |
| 41 |
Characterization of AN6001, a positive allosteric modulator of α6β2-containing nicotinic acetylcholine receptors
Marloes van Hout, Jessica L. Klein, Philip Kiær Ahring et al. · Biochemical Pharmacology
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27 Dec 2019 |
7 |
| 42 |
The shortcoming of using glibenclamide in exploratory clinical headache provocation studies
Palle Christophersen, Tino Dyhring · Cephalalgia
Open access |
Dec 2023 |
6 |
| 43 |
No selective action verb impairment in patients with Parkinson's disease: Evidence from Danish patients reading naturalistic texts, a Commentary on García et al., 2018
Marie Louise Holm Møller, Sabine Hagen Høj, Karen Østergaard et al. · Cortex
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9 Sep 2022 |
6 |
| 44 |
Synthetic resin acid derivatives selectively open the hKV7.2/7.3 channel and prevent epileptic seizures
Nina E. Ottosson, Malin Silverå Ejneby, Xiongyu Wu et al. · Epilepsia
Open access |
4 Jun 2021 |
6 |
| 45 |
What is this thing called “Post-Olympic Blues”? An Exploratory Study Among Danish Olympic Athletes
Gregory Michael Diment, Nina Due Stagis, Andreas Küttel · Scandinavian Journal of Sport and Exercise Psychology
Open access |
24 May 2023 |
5 |
| 46 |
Accurate and affordable assessment of physiological and pathological tremor in rodents using the accelerometer of a smartphone
Eva Maria Meier Carlsen, Dipak Vasantrao Amrutkar, Karin Sandager‐Nielsen et al. · Journal of Neurophysiology
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10 Jul 2019 |
5 |
| 47 |
Weight Loss, Improved Body Composition and Fat Distribution by Tesomet in Acquired Hypothalamic Obesity
Kim Huynh, Marianne Klose, Kim Krogsgaard et al. · Journal of the Endocrine Society
Open access |
May 2021 |
4 |
| 48 |
Optogenetics and Optical Tools in Automated Patch Clamping
Kim Boddum, Peder Skafte-Pedersen, Jean‐François Rolland et al. · Methods in molecular biology
Book chapter |
29 Oct 2020 |
4 |
| 49 |
Retroviral glycoprotein-mediated immune suppression via the potassium channel KCa3.1 – A new strategy for amelioration of inflammatory bowel diseases
Magdalena Janina Laska, Jesper Bonnet Moeller, Jonas Heilskov Graversen et al. · Clinical Immunology
Open access |
26 Jul 2022 |
3 |
| 50 |
Recent Developments in the Pharmacology of Epithelial Ca2+-Activated K+ Channels
Antônio Egídio Nardi, Søren‐Peter Olesen, Palle Christophersen
Book chapter |
14 Dec 2015 |
3 |