| 1 |
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
Clotilde Théry et al. · Journal of Extracellular Vesicles
Open access382 authors |
23 Nov 2018 |
11,535 |
| 2 |
Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction
John J.V. McMurray et al. · New England Journal of Medicine
Open access |
19 Sep 2019 |
7,135 |
| 3 |
Biological properties of extracellular vesicles and their physiological functions
María Yáñez‐Mó et al. · Journal of Extracellular Vesicles
Open access |
2015 |
6,130 |
| 4 |
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Daniel J. Klionsky et al. · Autophagy
Open access2,467 authors |
2 Jan 2016 |
6,023 |
| 5 |
EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update
Josef S Smolen et al. · Annals of the Rheumatic Diseases
Open access |
6 Mar 2017 |
5,808 |
| 6 |
Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure
Milton Packer et al. · New England Journal of Medicine
Open access |
28 Aug 2020 |
5,214 |
| 7 |
An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients
Balázs Győrffy, András Lánczky, Aron Charles Eklund et al. · Breast Cancer Research and Treatment
|
17 Dec 2009 |
4,380 |
| 8 |
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
Joshua A Welsh et al. · Journal of Extracellular Vesicles
Open access |
Feb 2024 |
4,377 |
| 9 |
A Randomized Comparison of a Sirolimus-Eluting Stent with a Standard Stent for Coronary Revascularization
Marie‐Claude Morice, Patrick W.J.C. Serruys, José Eduardo Sousa et al. · New England Journal of Medicine
Open access |
6 Jun 2002 |
4,047 |
| 10 |
A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing
Pablo Landgraf et al. · Cell
Open access |
Jun 2007 |
3,706 |
| 11 |
2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension
Giuseppe Mancia et al. · Journal of Hypertension
Open access |
24 Jun 2023 |
3,385 |
| 12 |
Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial
Hertzel C. Gerstein et al. · The Lancet
Open access1,458 authors |
9 Jun 2019 |
3,173 |
| 13 |
Prediabetes: a high-risk state for diabetes development
Ádám Gyula Tabák, Christian Herder, Wolfgang Rathmann et al. · The Lancet
Open access |
Jun 2012 |
3,020 |
| 14 |
Once-Yearly Zoledronic Acid for Treatment of Postmenopausal Osteoporosis
Dennis M. Black et al. · New England Journal of Medicine
Open access |
3 May 2007 |
2,988 |
| 15 |
Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction
Scott David Solomon et al. · New England Journal of Medicine
Open access |
27 Aug 2022 |
2,863 |
| 16 |
EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update
Josef S Smolen et al. · Annals of the Rheumatic Diseases
Open access |
22 Jan 2020 |
2,807 |
| 17 |
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1
Daniel J. Klionsky et al. · Autophagy
Open access2,930 authors |
2 Jan 2021 |
2,743 |
| 18 |
Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles
Jan O. Lötvall, Andrew Francis Hill, Fred H. Hochberg et al. · Journal of Extracellular Vesicles
Open access |
2014 |
2,741 |
| 19 |
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
Jeremy Schwartzentruber et al. · Nature
|
27 Jan 2012 |
2,736 |
| 20 |
Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017
Christina Fitzmaurice et al. · JAMA Oncology
Open access628 authors |
27 Sep 2019 |
2,699 |
| 21 |
Diabetic Neuropathies: Update on Definitions, Diagnostic Criteria, Estimation of Severity, and Treatments
Solomon Hailemariam Tesfaye, Andrew J.M. Boulton, Peter James Dyck et al. · Diabetes Care
Open access |
28 Sep 2010 |
2,689 |
| 22 |
Catheter Ablation for Atrial Fibrillation with Heart Failure
NASSIR F. MARROUCHE, Johannes Brachmann, Dietrich Andresen et al. · New England Journal of Medicine
|
31 Jan 2018 |
2,511 |
| 23 |
Tracking the Evolution of Non–Small-Cell Lung Cancer
Mariam Jamal‐Hanjani et al. · New England Journal of Medicine
Open access |
26 Apr 2017 |
2,501 |
| 24 |
Initial Invasive or Conservative Strategy for Stable Coronary Disease
David Joel Maron et al. · New England Journal of Medicine
Open access |
30 Mar 2020 |
2,464 |
| 25 |
Prolactin: Structure, Function, and Regulation of Secretion
Marc E. Freeman, Béla Kanyicska, Anna A. Lerant et al. · Physiological Reviews
Review |
10 Jan 2000 |
2,460 |
| 26 |
Standardization of sample collection, isolation and analysis methods in extracellular vesicle research
Kenneth Whitaker Witwer, Edit I. Buzás, Lynne Bemis et al. · Journal of Extracellular Vesicles
Open access |
2013 |
2,457 |
| 27 |
Rivaroxaban with or without Aspirin in Stable Cardiovascular Disease
John W. Eikelboom et al. · New England Journal of Medicine
Open access |
27 Aug 2017 |
2,456 |
| 28 |
Angiotensin–Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction
Scott David Solomon et al. · New England Journal of Medicine
Open access |
Sep 2019 |
2,429 |
| 29 |
Durvalumab plus platinum–etoposide versus platinum–etoposide in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): a randomised, controlled, open-label, phase 3 trial
Luis G Paz-Ares et al. · The Lancet
246 authors |
4 Oct 2019 |
2,310 |
| 30 |
Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles
Bence György, Tamás Géza Szabó, Mária Pásztói et al. · Cellular and Molecular Life Sciences
Open access |
10 May 2011 |
2,104 |
| 31 |
Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019
Jonathan Kocarnik et al. · JAMA Oncology
Open access601 authors |
30 Dec 2021 |
2,100 |
| 32 |
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
Christopher Abbosh et al. · Nature
Open access104 authors |
25 Apr 2017 |
1,978 |
| 33 |
Genome-wide association study identifies five new schizophrenia loci
Stephan Ripke et al. · Nature Genetics
Open access196 authors |
18 Sep 2011 |
1,966 |
| 34 |
Third European Evidence-based Consensus on Diagnosis and Management of Ulcerative Colitis. Part 1: Definitions, Diagnosis, Extra-intestinal Manifestations, Pregnancy, Cancer Surveillance, Surgery, and Ileo-anal Pouch Disorders
Fernando Magro, Paolo Gionchetti, Rami Eliakim et al. · Journal of Crohn s and Colitis
Open access |
2 Feb 2017 |
1,931 |
| 35 |
EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2022 update
Josef S Smolen et al. · Annals of the Rheumatic Diseases
Open access |
10 Nov 2022 |
1,921 |
| 36 |
Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma
Dominik Sturm et al. · Cancer Cell
Open access |
Oct 2012 |
1,881 |
| 37 |
Web-Based Survival Analysis Tool Tailored for Medical Research (KMplot): Development and Implementation
András Lánczky, Balázs Győrffy · Journal of Medical Internet Research
Open access |
6 May 2021 |
1,863 |
| 38 |
Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE): Determining Therapeutic Goals for Treat-to-Target
Laurent Peyrin‐Biroulet et al. · The American Journal of Gastroenterology
Open access |
25 Aug 2015 |
1,861 |
| 39 |
Ustekinumab as Induction and Maintenance Therapy for Crohn’s Disease
Brian G. Feagan et al. · New England Journal of Medicine
Open access |
16 Nov 2016 |
1,860 |
| 40 |
Suicide prevention strategies revisited: 10-year systematic review
Gil Zalsman, Keith E Hawton, Danuta Wasserman et al. · The Lancet Psychiatry
ReviewOpen access |
11 Jun 2016 |
1,792 |
| 41 |
Survival analysis across the entire transcriptome identifies biomarkers with the highest prognostic power in breast cancer
Balázs Győrffy · Computational and Structural Biotechnology Journal
Open access |
2021 |
1,774 |
| 42 |
Common variants conferring risk of schizophrenia
†Genetic Risk and Outcome in Psychosis (GROUP) et al. · Nature
Open access |
Jul 2009 |
1,723 |
| 43 |
A Meta-Analysis of Cognitive Remediation for Schizophrenia: Methodology and Effect Sizes
Til Wykes, Vyv C. Huddy, Caroline Cellard et al. · American Journal of Psychiatry
Review |
15 Mar 2011 |
1,705 |
| 44 |
ESHRE guideline: endometriosis
Christian M. Becker et al. · Human Reproduction Open
Open access |
2022 |
1,629 |
| 45 |
Prevalence and correlates of adult attention-deficit hyperactivity disorder: meta-analysis
Viktória Simon, Pál Czobor, Sára Bálint et al. · The British Journal of Psychiatry
Open access |
27 Feb 2009 |
1,610 |
| 46 |
2016 update of the ASAS-EULAR management recommendations for axial spondyloarthritis
Désirée M F M van der Heijde et al. · Annals of the Rheumatic Diseases
Open access |
13 Jan 2017 |
1,593 |
| 47 |
Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): a multicentre, randomised, double-blind, controlled trial
Johannes F.E. Mann, Roland Erich Schmieder, Matthew McQueen et al. · The Lancet
|
Aug 2008 |
1,593 |
| 48 |
Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paper
Thomas Lener et al. · Journal of Extracellular Vesicles
Open access |
2015 |
1,591 |
| 49 |
Daratumumab, Bortezomib, and Dexamethasone for Multiple Myeloma
Antonio Pierangelo Palumbo, Asher Alban Chanan-Khan, Katja Christina Weisel et al. · New England Journal of Medicine
Open access |
24 Aug 2016 |
1,535 |
| 50 |
Validation of miRNA prognostic power in hepatocellular carcinoma using expression data of independent datasets
Ádám M. Nagy, András Lánczky, Otília Menyhárt et al. · Scientific Reports
Open access |
11 Jun 2018 |
1,472 |
