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Institution · SilicoLife (Portugal)

Most cited papers from SilicoLife (Portugal)

What are the most cited papers from SilicoLife (Portugal)?

The most cited paper from SilicoLife (Portugal) is "Big data in healthcare: management, analysis and future prospects" (Sabyasachi Dash, Sushil Kumar Shakyawar, Mohit Sharma et al., 2019), with 1,770 citations. Next come "MEMOTE for standardized genome-scale metabolic model testing" (572) and "National Food, Nutrition, and Physical Activity Survey of the Portuguese General Population (2015-2016): Protocol for Design and Development" (132).

Showing 50 of 50 papers. Every paper is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Big data in healthcare: management, analysis and future prospects Sabyasachi Dash, Sushil Kumar Shakyawar, Mohit Sharma et al. · Journal Of Big Data Open access 19 Jun 2019 1,770
2 MEMOTE for standardized genome-scale metabolic model testing Christian Lieven et al. · Nature Biotechnology Open access Mar 2020 572
3 National Food, Nutrition, and Physical Activity Survey of the Portuguese General Population (2015-2016): Protocol for Design and Development Carla Maria Moura Lopes, Duarte P.M. Torres, Andréia Oliveira et al. · JMIR Research Protocols Open access 15 Feb 2018 132
4 In Silico Constraint-Based Strain Optimization Methods: the Quest for Optimal Cell Factories Paulo Maia, Miguel Rocha, Isabel Rocha · Microbiology and Molecular Biology Reviews ReviewOpen access 25 Nov 2015 130
5 A Review of Dynamic Modeling Approaches and Their Application in Computational Strain Optimization for Metabolic Engineering Osvaldo D. Kim, Miguel Rocha, Paulo Maia · Frontiers in Microbiology Open access 31 Jul 2018 110
6 National Food, Nutrition and Physical Activity Survey of the Portuguese general population Carla Maria Moura Lopes, Duarte P.M. Torres, Andréia Oliveira et al. · EFSA Supporting Publications Open access Dec 2017 76
7 Current state and challenges for dynamic metabolic modeling Eleni Vasilakou, Daniel Machado, Axel Theorell et al. · Current Opinion in Microbiology ReviewOpen access 26 Jul 2016 46
8 Parasite Glycobiology: A Bittersweet Symphony João Alexandre Rodrigues, Álvaro Acosta-Serrano, Markus Aebi et al. · PLoS Pathogens Open access 12 Nov 2015 46
9 Reconstruction of a genome-scale metabolic model for Actinobacillus succinogenes 130Z Bruno Pereira, Joana Miguel, Paulo Vilaça et al. · BMC Systems Biology Open access 30 May 2018 37
10 Metabolic engineering strategies for butanol production in Escherichia coli Sofia Ferreira, Rui Pereira, A. Wahl et al. · Biotechnology and Bioengineering Open access 6 May 2020 34
11 Memote: A community driven effort towards a standardized genome-scale metabolic model test suite Christian Lieven et al. · bioRxiv (Cold Spring Harbor Laboratory) PreprintOpen access 21 Jun 2018 31
12 Curcumin biosynthesis from ferulic acid by engineered Saccharomyces cerevisiae João Rainha, Joana L. Rodrigues, Cristiana Faria et al. · Biotechnology Journal 9 Dec 2021 27
13 Model‐guided development of an evolutionarily stable yeast chassis Filipa M. Pereira, Hélder Lopes, Paulo Maia et al. · Molecular Systems Biology Open access Jul 2021 19
14 Genome-Wide Semi-Automated Annotation of Transporter Systems Óscar Dias, Daniel G. Gomes, Paulo Vilaça et al. · IEEE Transactions on Computational Biology and Bioinformatics Open access 11 Feb 2016 19
15 Discovery and implementation of a novel pathway for n-butanol production via 2-oxoglutarate Sofia Ferreira, Rui Pereira, Filipe Liu et al. · Biotechnology for Biofuels Open access 29 Sep 2019 17
16 Genetic variants as ovarian cancer first-line treatment hallmarks: A systematic review and meta-analysis Joana Assis, Carina Pereira, Augusto Nogueira et al. · Cancer Treatment Reviews Review 23 Oct 2017 17
17 Integrating system dynamics and machine learning for environmental impact analysis of building materials in the demolition process Babatunde Oluwaseun Ajayi, Mayowa Emmanuel Bamisaye, Hugo Macedo et al. · Scientific Reports Open access 25 Jul 2025 10
18 Computer-aided design and implementation of efficient biosynthetic pathways to produce high added-value products derived from tyrosine in Escherichia coli Sofia Ferreira, Alexandra Balola, Anastasia Sveshnikova et al. · Frontiers in Bioengineering and Biotechnology Open access 24 Jun 2024 10
19 Comparison of pathway analysis and constraint-based methods for cell factory design Vítor Vieira, Paulo Maia, Miguel Rocha et al. · BMC Bioinformatics Open access 20 Jun 2019 10
20 Development of an information retrieval tool for biomedical patents Tiago L. Alves, Rúben Rodrigues, Hugo Costa et al. · Computer Methods and Programs in Biomedicine Open access 14 Mar 2018 10
21 Comparison analysis of PM transverse flux outer rotor machines with and without magnetic shunts Oleksandr Dobzhanskyi, Rupert Gouws, Ebrahim Amiri Conference paper Sep 2016 10
22 Delay sensing for long-term variations and defects monitoring in safety–critical applications J. C. Vazquez, Victor H. Champac, Adriel Ziesemer et al. · Analog Integrated Circuits and Signal Processing 6 Oct 2011 9
23 An integrated network visualization framework towards metabolic engineering applications Alberto Noronha, Paulo Vilaça, Miguel Rocha · BMC Bioinformatics Open access Dec 2014 8
24 Analyzing and Designing Cell Factories with OptFlux Paulo Vilaça, Paulo Maia, Hugo Giesteira et al. · Methods in molecular biology Book chapter 8 Dec 2017 7
25 CBFA: phenotype prediction integrating metabolic models with constraints derived from experimental data Rafael Carreira, Pedro Evangelista, Paulo Maia et al. · BMC Systems Biology Open access Dec 2014 7
26 Development of Text Mining Tools for Information Retrieval from Patents Tiago L. Alves, Rúben Rodrigues, Hugo Costa et al. · Advances in intelligent systems and computing Conference paperOpen access 2017 5
27 Identification of robust strain designs via tandem pFBA/LMOMA phenotype prediction Paulo Maia, Isabel Rocha, Miguel Rocha · Proceedings of the Genetic and Evolutionary Computation Conference Companion Conference paperOpen access 11 Jul 2017 4
28 A Critical Evaluation of Automatic Atom Mapping Algorithms and Tools Nuno Sampaio Osório, Paulo Vilaça, Miguel Rocha · Advances in intelligent systems and computing Conference paperOpen access 2017 4
29 An Algorithm to Assemble Gene-Protein-Reaction Associations for Genome-Scale Metabolic Model Reconstruction João Cardoso, Paulo Vilaça, Simão Soares et al. · Lecture notes in computer science Conference paperOpen access 2012 4
30 Yeast chassis design for production of dicarboxylic acids Filipa M. Pereira, Helena Lopes, Paulo Maia et al. · New Biotechnology Open access 22 Sep 2018 3
31 An integrated framework for strain optimization Paulo Maia, Isabel Rocha, Miguel Rocha Conference paperOpen access Jun 2013 3
32 A new genome-scale metabolic model of oleaginous microalgae with refined lipid metabolism clarifies Microchloropsis gaditana mutant phenotypes Clémence M Dupont-Thibert, Sylvaine Roy, Sylvia Mendes Carneiro et al. · Bioresource Technology Open access 9 Nov 2025 2
33 Exploring Xylella fastidiosa’s Metabolic Traits Using a GSM Model of the Phytopathogenic Bacterium Alexandre Oliveira, Emanuel Cunha, Miguel Ângelo Fernandes da Silva et al. · Lecture notes in networks and systems Conference paper 19 Oct 2022 2
34 Development of a Machine Learning Framework for Biomedical Text Mining Rúben Rodrigues, Hugo Costa, Miguel Rocha · Advances in intelligent systems and computing Conference paperOpen access 2016 2
35 Development of an Integrated Framework for Minimal Cut Set Enumeration in Constraint-Based Models Vítor Vieira, Paulo Maia, Isabel Rocha et al. · Advances in intelligent systems and computing Conference paper 2016 2
36 TNA4OptFlux – a software tool for the analysis of strain optimization strategies José P. Pinto, Rui Pereira, João Cardoso et al. · BMC Research Notes Open access 3 May 2013 2
37 Network Visualization Tools to Enhance Metabolic Engineering Platforms Alberto Noronha, Paulo Vilaça, Miguel Rocha · Advances in intelligent systems and computing Book chapter 2013 2
38 A new genome-scale metabolic model of oleaginous microalgae with refined lipid metabolism elucidates Microchloropsis gaditana mutant phenotypes. Clémence M Dupont-Thibert, Sylvaine Roy, Sónia Carneiro et al. · bioRxiv (Cold Spring Harbor Laboratory) PreprintOpen access 6 Dec 2023 1
39 Predicting the number of biochemical transformations needed to synthesize a compound João Correia, Rafael Carreira, Vítor Pereira et al. · 2022 International Joint Conference on Neural Networks (IJCNN) Conference paperOpen access 18 Jul 2022 1
40 In Silico Predictions for Fucoxanthin Production by the Diatom Phaeodactylum Tricornutum Cláudia Marlene Bauer, Paulo Vilaça, Fernanda Ramlov et al. · Advances in intelligent systems and computing Conference paper 16 Aug 2018 1
41 Development of a Framework for Metabolic Pathway Analysis-Driven Strain Optimization Methods Vítor Vieira, Paulo Maia, Isabel Rocha et al. · Interdisciplinary Sciences Computational Life Sciences Open access 25 Feb 2017 1
42 Reconstructing transcriptional Regulatory Networks using data integration and Text Mining Rafael Teodósio Pereira, Hugo Costa, Sónia Carneiro et al. Conference paperOpen access Nov 2015 1
43 Extracting kinetic information from literature with KineticRE Ana Alão Freitas, Hugo Costa, Miguel Rocha et al. · PubMed Open access 2015 1
44 Turnover Dependent Phenotypic Simulation: A Quantitative Constraint-Based Simulation Method That Accommodates All Main Strain Design Strategies Rui Pereira, Paulo Vilaça, Paulo Maia et al. · ACS Synthetic Biology Open access 29 Mar 2019 1
45 A Dynamically Reconfigurable Power Management System With Self-Monitoring Capabilities for Energy-Efficient SoCs Henrique A. Pocinho, Rodrigo Capeleiro, Tiago Moita et al. · IEEE Open Journal of the Solid-State Circuits Society Open access 2025 0
46 Reconstruction of a genome-scale metabolic model of Microchloropsis gaditana with detailed lipid metabolism. Clémence Dupont Thibert, Sónia Carneiro, Pereira, Bruno et al. · HAL (Le Centre pour la Communication Scientifique Directe) Conference paper 10 Jul 2022 0
47 Delta-Sigma Control Loop For Energy-Efficient Electrical Stimulation with Arbitrary-Shape Stimuli Amin Rashidi, Hassan Rivandi, Miloš Grubor et al. Conference paper 19 Oct 2023 0
48 Automating the Extraction of Essential Genes from Literature Rúben Rodrigues, Hugo Costa, Miguel Rocha · Lecture notes in computer science Conference paperOpen access 2018 0
49 Reg4OptFlux: an OptFlux plug-in that comprises meta-heuristics approaches for Metabolic engineering using integrated models Orlando Rocha, Paulo Vilaça, Miguel Rocha et al. Conference paperOpen access Jul 2014 0
50 A Text Mining Approach for the Extraction of Kinetic Information from Literature Ana Alão Freitas, Hugo Costa, Miguel Rocha et al. · Advances in intelligent systems and computing Book chapterOpen access 2015 0

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.