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Inhibition of Vps34 reprograms cold into hot inflamed tumors and improves anti–PD-1/PD-L1 immunotherapy
Muhammad Zaeem Noman, Santiago Parpal, Kris Van Moer et al. · Science Advances
Open access |
29 Apr 2020 |
260 |
| 2 |
Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination
Nina Gustafsson et al. · Nature Communications
Open access |
18 Sep 2018 |
133 |
| 3 |
Targeting autophagy by small molecule inhibitors of vacuolar protein sorting 34 (Vps34) improves the sensitivity of breast cancer cells to Sunitinib
Matheus Dyczynski, Yasmin Yu, Magdalena Otrocka et al. · Cancer Letters
Open access |
25 Jul 2018 |
112 |
| 4 |
Therapeutic implications of tumor interstitial acidification
Iryna Kolosenko, Sofia Avnet, Nicola Baldini et al. · Seminars in Cancer Biology
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7 Feb 2017 |
100 |
| 5 |
Cisplatin resistance can be curtailed by blunting Bnip3-mediated mitochondrial autophagy
Caterina Vianello, Veronica Cocetta, Daniela Catanzaro et al. · Cell Death and Disease
Open access |
22 Apr 2022 |
59 |
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Novel Class of Potent and Cellularly Active Inhibitors Devalidates MTH1 as Broad-Spectrum Cancer Target
Manuel Ellermann et al. · ACS Chemical Biology
Open access |
5 Jul 2017 |
58 |
| 7 |
Pharmacokinetic profile of N-acetylcysteine amide and its main metabolite in mice using new analytical method
Rui He, Wenyi Zheng, Tobias Ginman et al. · European Journal of Pharmaceutical Sciences
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15 Nov 2019 |
35 |
| 8 |
Toward β-Secretase-1 Inhibitors with Improved Isoform Selectivity
Patrik Johansson, Karin Kaspersson, Ian K. Gurrell et al. · Journal of Medicinal Chemistry
Open access |
4 Apr 2018 |
33 |
| 9 |
Creation of a Novel Class of Potent and Selective MutT Homologue 1 (MTH1) Inhibitors Using Fragment-Based Screening and Structure-Based Drug Design
Fredrik Rahm et al. · Journal of Medicinal Chemistry
Open access |
27 Feb 2018 |
33 |
| 10 |
Firing up the cold tumors by targeting Vps34
Bassam Janji, Meriem Hasmim, Santiago Parpal et al. · OncoImmunology
Open access |
2020 |
32 |
| 11 |
Rescue of Escherichia coli auxotrophy by de novo small proteins
Arianne M. Babina, Serhiy Surkov, Weihua Ye et al. · eLife
Open access |
15 Mar 2023 |
27 |
| 12 |
Evaluation of drying methods on the content of some bio-actives (lycopene, -carotene and ascorbic acid) of tomato slices
Jelili Babatunde Hussein, Mayowa Saheed Sanusi, Kalep Bulus Filli · African Journal of Food Science
Open access |
7 Nov 2016 |
26 |
| 13 |
Flowability characterization of nanopowders
Epameinondas Xanthakis, J. Ruud van Ommen, Lı́lia Ahrné · Powder Technology
Open access |
14 Aug 2015 |
26 |
| 14 |
NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir
Si Min Zhang, Daniel Rehling, Ann‐Sofie Jemth et al. · Cell chemical biology
Open access |
29 Jun 2021 |
25 |
| 15 |
Pathobiology and Therapeutic Implications of Tumor Acidosis
Jenny Viklund, Sofia Avnet, Angelo De Milito · Current Medicinal Chemistry
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14 Sep 2017 |
16 |
| 16 |
Combining VPS34 inhibitors with STING agonists enhances type I interferon signaling and anti‐tumor efficacy
Yasmin Yu et al. · Molecular Oncology
Open access |
20 Mar 2024 |
15 |
| 17 |
Aerobic Homocoupling of Arylboronic Acids Catalyzed by Regenerable Pd(II)@MIL‐88B‐NH2(Cr)
Alejandro Valiente, Sergio Carrasco, Amparo Sanz‐Marco et al. · ChemCatChem
Open access |
16 Apr 2019 |
14 |
| 18 |
A general covalent binding model between cytotoxic selenocompounds and albumin revealed by mass spectrometry and X-ray absorption spectroscopy
Wenyi Zheng, Rui He, Roberto López Boada et al. · Scientific Reports
Open access |
27 Jan 2020 |
13 |
| 19 |
The Cockayne syndrome protein B is involved in the repair of 5-AZA-2′-deoxycytidine-induced DNA lesions
Estefanía Burgos‐Morón, José Manuel Calderón‐Montaño, Nuria Pastor et al. · Oncotarget
Open access |
12 Oct 2018 |
9 |
| 20 |
How to Computationally Stack the Deck for Hit-to-Lead Generation: In Silico Molecular Interaction Energy Profiling for de Novo siRNA Guide Strand Surrogate Selection
Paulette A. Greenidge, Marcel J. J. Blommers, John P. Priestle et al. · Journal of Chemical Information and Modeling
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25 Apr 2019 |
6 |
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Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Cancer Metabolism
Sofia Avnet, Nicola Baldini, Lucie Brisson et al. · Frontiers in Oncology
Open access |
3 Oct 2018 |
5 |
| 22 |
Rapid and Robust Quantification of p-Xyleneselenocyanate in Plasma via Derivatization
Wenyi Zheng, Fadwa Benkessou, Brigitte Twelkmeyer et al. · Analytical Chemistry
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22 Jun 2017 |
5 |
| 23 |
DCPS is a synthetic lethal therapeutic target in acute myeloid leukemia expressing low levels of FHIT
Francesca Grassi, Madhurendra Singh, Simon Moussaud et al. · Leukemia
Open access |
26 Jun 2025 |
2 |
| 24 |
Developmentally dynamic, non-convergent transcriptomic profiles in CNV models for schizophrenia risk
Hayley French, Shuyang Yao, Lisa Bast et al. · Molecular Psychiatry
Open access |
18 Jun 2026 |
0 |
| 25 |
Integrated FHIT and IDH2 biomarker profiling predicts lethal sensitivity to DCPS inhibition in Acute Myeloid Leukemia and Myelodysplastic syndrome
Francesca Grassi, Lisa Bast, Madhurendra Singh et al. · Discover Oncology
Open access |
26 Mar 2026 |
0 |
| 26 |
Loop dynamics and evolvability in the TIM-barrel proteins of histidine and tryptophan biosynthesis
Adrian Romero‐Rivera, Marina Corbella, Antonietta Parracino et al. · Biophysical Journal
Open access |
Feb 2023 |
0 |
| 27 |
EVB Parameters for the Manuscript: Complex Loop Dynamics Underpin Activity, Specificity and Evolvability in the (Beta-Alpha)8 Barrel Enzymes of Histidine and Tryptophan Biosynthesis
Adrian Romero‐Rivera, Marina Corbella, Lynn Kamerlin · Zenodo (CERN European Organization for Nuclear Research)
Open access |
27 Jan 2022 |
0 |
| 28 |
Complex Loop Dynamics Underpin Activity, Specificity and Evolvability in the (βα)8 Barrel Enzymes of Histidine and Tryptophan Biosynthesis
Adrian Romero‐Rivera, Marina Corbella, Antonietta Parracino et al. · ChemRxiv
PreprintOpen access |
26 Jan 2022 |
0 |
| 29 |
The Advantages of Micro-Cal™ Auto-iTC200 for Secondary Screening in a Fragment-based Drug Discovery Campaign
Natalia Markova, Ronan O’Brien, Jessica Martinsson et al. · Europe PMC (PubMed Central)
Open access |
May 2013 |
0 |