Most cited papers from The Francis Crick Institute
What are the most cited papers from The Francis Crick Institute?
The most cited paper from The Francis Crick Institute is "Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018" (Lorenzo Galluzzi et al., 2018), with 6,760 citations. Next come "Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)" (6,023) and "The nf-core framework for community-curated bioinformatics pipelines" (4,389).
Showing 50 of 60 papers. Every paper with more than 1,005 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 Lorenzo Galluzzi et al. · Cell Death and Differentiation | 23 Jan 2018 | 6,760 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Daniel J. Klionsky et al. · Autophagy | 2 Jan 2016 | 6,023 |
| 3 | The nf-core framework for community-curated bioinformatics pipelines Philip Ewels, Alexander Peltzer, Sven Fillinger et al. · Nature Biotechnology | 13 Feb 2020 | 4,389 |
| 4 | A framework for advancing our understanding of cancer-associated fibroblasts Erik A. Sahai et al. · Nature reviews. Cancer | 24 Jan 2020 | 3,962 |
| 5 | The repertoire of mutational signatures in human cancer Ludmil B. Alexandrov et al. · Nature | 5 Feb 2020 | 3,854 |
| 6 | DIA-NN: neural networks and interference correction enable deep proteome coverage in high throughput Vadim Petrovich Demichev, Christoph B. Messner, Spyros I. Vernardis et al. · Nature Methods | 25 Nov 2019 | 3,652 |
| 7 | Improved protein structure prediction using potentials from deep learning Andrew Senior, Richard Evans, John Jumper et al. · Nature | 15 Jan 2020 | 3,622 |
| 8 | GISAID: Global initiative on sharing all influenza data – from vision to reality Yuelong Shu, John W. McCauley · Eurosurveillance | 30 Mar 2017 | 3,604 |
| 9 | Neutrophil extracellular traps in immunity and disease Venizelos Papayannopoulos · Nature reviews. Immunology | 9 Oct 2017 | 3,477 |
| 10 | Virus interference. I. The interferon Alick Isaacs, Jean-Michel Lindenmann · Proceedings of the Royal Society B Biological Sciences | 12 Sep 1957 | 3,446 |
| 11 | Pan-cancer analysis of whole genomes Lauri A. Aaltonen et al. · Nature | 5 Feb 2020 | 3,360 |
| 12 | The regulation of IL-10 production by immune cells Margarida Saraiva, Anne O’Garra · Nature reviews. Immunology | 15 Feb 2010 | 3,198 |
| 13 | Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade Nicholas McGranahan et al. · Science | 3 Mar 2016 | 3,177 |
| 14 | Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future Nicholas McGranahan, Charles Swanton · Cell | Feb 2017 | 3,002 |
| 15 | Development of tumor mutation burden as an immunotherapy biomarker: utility for the oncology clinic Timothy An-thy Chan, Mark M. Yarchoan, Elizabeth M. Jaffee et al. · Annals of Oncology | Nov 2018 | 2,932 |
| 16 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 Daniel J. Klionsky et al. · Autophagy | 2 Jan 2021 | 2,743 |
| 17 | Classification of Intrinsically Disordered Regions and Proteins Robin van der Lee, Marija Buljan, Benjamin Lang et al. · Chemical Reviews | 29 Apr 2014 | 2,336 |
| 18 | Male development of chromosomally female mice transgenic for Sry Peter A. Koopman, John Gubbay, Nigel Vivian et al. · Nature | May 1991 | 2,242 |
| 19 | Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution Christopher Abbosh et al. · Nature | 25 Apr 2017 | 1,978 |
| 20 | Artificial intelligence in cancer imaging: Clinical challenges and applications Wenya Linda Bi, Ahmed Hosny, Matthew B. Schabath et al. · CA A Cancer Journal for Clinicians | 5 Feb 2019 | 1,886 |
| 21 | NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control Jan P. Böttcher, Eduardo Bonavita, Probir Chakravarty et al. · Cell | Feb 2018 | 1,883 |
| 22 | High burden and pervasive positive selection of somatic mutations in normal human skin Iñigo Martincorena, Amit Roshan, Moritz Gerstung et al. · Science | 22 May 2015 | 1,880 |
| 23 | Universal Patterns of Selection in Cancer and Somatic Tissues Iñigo Martincorena, Keiran M. Raine, Moritz Gerstung et al. · Cell | 19 Oct 2017 | 1,706 |
| 24 | A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes John Gubbay, Jérôme Collignon, Peter A. Koopman et al. · Nature | Jul 1990 | 1,691 |
| 25 | Molecular definitions of autophagy and related processes Lorenzo Galluzzi et al. · The EMBO Journal | 8 Jun 2017 | 1,670 |
| 26 | High sensitivity of detection of human malaria parasites by the use of nested polymerase chain reaction Georges Snounou, Suganya Viriyakosol, Xin Ping Zhu et al. · Molecular and Biochemical Parasitology | Oct 1993 | 1,647 |
| 27 | Chromosomal instability drives metastasis through a cytosolic DNA response Samuel F. W. Bakhoum et al. · Nature | 17 Jan 2018 | 1,621 |
| 28 | The role of ROS in tumour development and progression Eric C. Cheung, Karen H. Vousden · Nature reviews. Cancer | 31 Jan 2022 | 1,613 |
| 29 | Autophagy in major human diseases Daniel J. Klionsky et al. · The EMBO Journal | 30 Aug 2021 | 1,608 |
| 30 | Male sex identified by global COVID-19 meta-analysis as a risk factor for death and ITU admission Hannah Peckham, Nina M. de Gruijter, Charles Raine et al. · Nature Communications | 9 Dec 2020 | 1,599 |
| 31 | Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA M.C. Liu et al. · Annals of Oncology | 30 Mar 2020 | 1,567 |
| 32 | Autophagy pathway: Cellular and molecular mechanisms Li Yu, Yang Chen, Sharon A. Tooze · Autophagy | 21 Sep 2017 | 1,531 |
| 33 | Genetic mechanisms of critical illness in COVID-19 The GenOMICC Investigators et al. · Nature | 11 Dec 2020 | 1,515 |
| 34 | The spectrum of latent tuberculosis: rethinking the biology and intervention strategies Clifton E. Barry, Helena I. Boshoff, Veronique Anne Dartois et al. · Nature Reviews Microbiology | 26 Oct 2009 | 1,466 |
| 35 | Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution Nicholas McGranahan et al. · Cell | 26 Oct 2017 | 1,361 |
| 36 | deconstructSigs: delineating mutational processes in single tumors distinguishes DNA repair deficiencies and patterns of carcinoma evolution Rachel Rosenthal, Nicholas McGranahan, Javier Herrero et al. · Genome biology | 22 Feb 2016 | 1,358 |
| 37 | Sequence requirements for nuclear location of simian virus 40 large-T antigen Daniel Kalderon, William David Richardson, Alexander F. Markham et al. · Nature | 6 Sep 1984 | 1,331 |
| 38 | TrackMate 7: integrating state-of-the-art segmentation algorithms into tracking pipelines Dmitry Ershov, Minh-Son Phan, Joanna W. Pylvänäinen et al. · Nature Methods | 2 Jun 2022 | 1,329 |
| 39 | High-throughput discovery of novel developmental phenotypes Mary E. Dickinson et al. · Nature | 13 Sep 2016 | 1,321 |
| 40 | Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosis Annika Warnatsch, Marianna Ioannou, Qian Wang et al. · Science | 16 Jul 2015 | 1,292 |
| 41 | Content-aware image restoration: pushing the limits of fluorescence microscopy MARTIN G. WEIGERT et al. · Nature Methods | 19 Nov 2018 | 1,258 |
| 42 | Role of the polycomb protein EED in the propagation of repressive histone marks Raphaël Margueron, Neil Justin, Katsuhito Ohno et al. · Nature | 20 Sep 2009 | 1,234 |
| 43 | Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer Matthew David Hellmann et al. · Cancer Cell | 12 Apr 2018 | 1,197 |
| 44 | Patterning the Vertebrate Neuraxis Andrew Lumsden, Robb K. Krumlauf · Science | 15 Nov 1996 | 1,151 |
| 45 | The evolutionary history of 2,658 cancers Moritz Gerstung et al. · Nature | 5 Feb 2020 | 1,149 |
| 46 | Biology and therapeutic potential of interleukin-10 Margarida Saraiva, Paulo Rufino Paulino Vieira, Anne O’Garra · The Journal of Experimental Medicine | 14 Oct 2019 | 1,145 |
| 47 | Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity Santiago Zelenay, Annemarthe G. van der Veen, Jan P. Böttcher et al. · Cell | Sep 2015 | 1,142 |
| 48 | Mutational signatures associated with tobacco smoking in human cancer Ludmil B. Alexandrov, Young Seok Ju, Kerstin Haase et al. · Science | 3 Nov 2016 | 1,137 |
| 49 | Mapping the human genetic architecture of COVID-19 COVID-19 Host Genetics Initiative et al. · Nature | 8 Jul 2021 | 1,130 |
| 50 | Genetic compensation triggered by mutant mRNA degradation Mohamed A. El-Brolosy, Zacharias Kontarakis, Andrea Rossi et al. · Nature | 3 Apr 2019 | 1,126 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.