Institution · The Hamner Institutes for Health Sciences
Most cited papers from The Hamner Institutes for Health Sciences
What are the most cited papers from The Hamner Institutes for Health Sciences?
The most cited paper from The Hamner Institutes for Health Sciences is "Toxicity Testing in the 21st Century: A Vision and a Strategy" (Daniel R. Krewski et al., 2010), with 1,703 citations. Next come "Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME" (1,303) and "Case Definition and Phenotype Standardization in Drug-Induced Liver Injury" (1,040).
Showing 50 of 60 papers. Every paper with more than 148 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Toxicity Testing in the 21st Century: A Vision and a Strategy Daniel R. Krewski et al. · Journal of Toxicology and Environmental Health Part B | 17 Jun 2010 | 1,703 |
| 2 | Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME Patrício Godoy et al. · Archives of Toxicology | Aug 2013 | 1,303 |
| 3 | Case Definition and Phenotype Standardization in Drug-Induced Liver Injury Guruprasad Padur Aithal, PB Watkins, Raúl J. Andrade et al. · Clinical Pharmacology & Therapeutics | 4 May 2011 | 1,040 |
| 4 | The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models Leming M. Shi et al. · Nature Biotechnology | 30 Jul 2010 | 922 |
| 5 | Reactive Oxygen Species as a Signal in Glucose-Stimulated Insulin Secretion Jingbo Pi, Yushi Bai, Qiang Zhang et al. · Diabetes | 27 Jun 2007 | 579 |
| 6 | In vitro models for liver toxicity testing. Valerie Y. Soldatow, Edward L. LeCluyse, Linda G. Griffith et al. · PubMed | 2013 | 467 |
| 7 | Inhaled carbon nanotubes reach the subpleural tissue in mice Jessica P. Ryman-Rasmussen, Mark F. Cesta, Arnold R. Brody et al. · Nature Nanotechnology | 25 Oct 2009 | 466 |
| 8 | Integration of Dosimetry, Exposure, and High-Throughput Screening Data in Chemical Toxicity Assessment Barbara A. Wetmore, John F. Wambaugh, Stephen Ferguson et al. · Toxicological Sciences | 26 Sep 2011 | 417 |
| 9 | Hepatic Autophagy Is Suppressed in the Presence of Insulin Resistance and Hyperinsulinemia Huiyu Liu, Jianmin Han, Sophia Y. Cao et al. · Journal of Biological Chemistry | 17 Sep 2009 | 387 |
| 10 | p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming Tetsuya Saito et al. · Nature Communications | 27 Jun 2016 | 383 |
| 11 | A comparison of batch effect removal methods for enhancement of prediction performance using MAQC-II microarray gene expression data Jie Luo et al. · The Pharmacogenomics Journal | 30 Jul 2010 | 368 |
| 12 | Organotypic liver culture models: Meeting current challenges in toxicity testing Edward L. LeCluyse, Rafal P. Witek, Melvin E. Andersen et al. · Critical Reviews in Toxicology | 15 May 2012 | 364 |
| 13 | Evaluation of the Association between Arsenic and Diabetes: A National Toxicology Program Workshop Review Elizabeth A. Maull, Habibul Ahsan, Joshua Edwards et al. · Environmental Health Perspectives | 10 Aug 2012 | 339 |
| 14 | ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function Jingbo Pi, Qiang Zhang, Jingqi Fu et al. · Toxicology and Applied Pharmacology | 10 Jun 2009 | 336 |
| 15 | Epigallocatechin-3-gallate (EGCG), A Green Tea Polyphenol, Suppresses Hepatic Gluconeogenesis through 5′-AMP-activated Protein Kinase Qu Fan Collins, Hui-Yu Liu, Jingbo Pi et al. · Journal of Biological Chemistry | 28 Aug 2007 | 333 |
| 16 | Toxicity Testing in the 21st Century: Bringing the Vision to Life Melvin E. Andersen, Daniel R. Krewski · Toxicological Sciences | 12 Dec 2008 | 328 |
| 17 | Perfluoroalkyl Acids and Related Chemistries—Toxicokinetics and Modes of Action Melvin E. Andersen, John L. Butenhoff, Shu‐Ching Chang et al. · Toxicological Sciences | 13 Nov 2007 | 322 |
| 18 | Deficiency in the Nuclear Factor E2-related Factor-2 Transcription Factor Results in Impaired Adipogenesis and Protects against Diet-induced Obesity Jingbo Pi, Laura Leung, Peng Xue et al. · Journal of Biological Chemistry | 20 Jan 2010 | 300 |
| 19 | Incorporating New Technologies Into Toxicity Testing and Risk Assessment: Moving From 21st Century Vision to a Data-Driven Framework Russell S. Thomas et al. · Toxicological Sciences | 19 Aug 2013 | 272 |
| 20 | Inhaled Multiwalled Carbon Nanotubes Potentiate Airway Fibrosis in Murine Allergic Asthma Jessica P. Ryman-Rasmussen, Earl W. Tewksbury, Owen R. Moss et al. · American Journal of Respiratory Cell and Molecular Biology | 11 Sep 2008 | 267 |
| 21 | GUDMAP Andrew P. McMahon, Bruce J. Aronow, Duncan R Davidson et al. · Journal of the American Society of Nephrology | 20 Feb 2008 | 265 |
| 22 | Meeting Report: Hazard Assessment for Nanoparticles—Report from an Interdisciplinary Workshop John M. Balbus, Andrew David Maynard, Vicki L. Colvin et al. · Environmental Health Perspectives | 13 Aug 2007 | 264 |
| 23 | Associations of Perfluoroalkyl Substances (PFAS) with Lower Birth Weight: An Evaluation of Potential Confounding by Glomerular Filtration Rate Using a Physiologically Based Pharmacokinetic Model (PBPK) Marc-André Verner, Anne E. Loccisano, Nils‐Halvdan Morken et al. · Environmental Health Perspectives | 21 May 2015 | 250 |
| 24 | Incorporating Human Dosimetry and Exposure into High-ThroughputIn VitroToxicity Screening Daniel Miller Rotroff, Barbara A. Wetmore, David J. Dix et al. · Toxicological Sciences | 16 Jul 2010 | 250 |
| 25 | Incorporating High-Throughput Exposure Predictions With Dosimetry-AdjustedIn VitroBioactivity to Inform Chemical Toxicity Testing Barbara A. Wetmore, John F. Wambaugh, Brittany Allen et al. · Toxicological Sciences | 6 Aug 2015 | 235 |
| 26 | Atrophic rhinitis: a CFD study of air conditioning in the nasal cavity Guilherme J. M. Garcia, Neil A. Bailie, Dário A. Martins et al. · Journal of Applied Physiology | 14 Jun 2007 | 231 |
| 27 | BMDExpress: a software tool for the benchmark dose analyses of genomic data Longlong Yang, Bruce C. Allen, Russell S. Thomas · BMC Genomics | 25 Oct 2007 | 217 |
| 28 | Temporal Concordance Between Apical and Transcriptional Points of Departure for Chemical Risk Assessment Russell S. Thomas, Scott C. Wesselkamper, Nina Ching Y. Wang et al. · Toxicological Sciences | 17 Apr 2013 | 215 |
| 29 | A systems biology perspective on Nrf2-mediated antioxidant response Qiang Zhang, Jingbo Pi, Courtney Georgette Woods et al. · Toxicology and Applied Pharmacology | 29 Aug 2009 | 215 |
| 30 | Quantitativein vitrotoin vivoextrapolation of cell-based toxicity assay results Miyoung Yoon, Jerry L. Campbell, Melvin E. Andersen et al. · Critical Reviews in Toxicology | 6 Jun 2012 | 215 |
| 31 | Metabolomics in Toxicology: Preclinical and Clinical Applications D. G. Robertson, Paul Brent Watkins, Michael D. Reily · Toxicological Sciences | 2 Dec 2010 | 210 |
| 32 | Nrf2 Protects Pancreatic β-Cells From Oxidative and Nitrosative Stress in Diabetic Model Mice Yoko Yagishita, Toshiaki Fukutomi, Akira Sugawara et al. · Diabetes | 2 Nov 2013 | 210 |
| 33 | Molecular mechanism of human Nrf2 activation and degradation: Role of sequential phosphorylation by protein kinase CK2 Jingbo Pi, Yushi Bai, Jeffrey M. Reece et al. · Free Radical Biology and Medicine | 11 Apr 2007 | 210 |
| 34 | Mechanism-based testing strategy using in vitro approaches for identification of thyroid hormone disrupting chemicals Albertinka Jacoba Murk, Eddy Rijntjes, Bas J. Blaauboer et al. · Toxicology in Vitro | 26 Feb 2013 | 209 |
| 35 | A Method to Integrate Benchmark Dose Estimates with Genomic Data to Assess the Functional Effects of Chemical Exposure Russell S. Thomas, Bruce C. Allen, Andy Nong et al. · Toxicological Sciences | 21 Apr 2007 | 209 |
| 36 | Toxicity Testing in the 21st Century: Defining New Risk Assessment Approaches Based on Perturbation of Intracellular Toxicity Pathways Sudin Bhattacharya, Qiang Zhang, Paul Lawford Carmichael et al. · PLoS ONE | 20 Jun 2011 | 207 |
| 37 | Estimating Toxicity-Related Biological Pathway Altering Doses for High-Throughput Chemical Risk Assessment Richard Judson, Robert J. Kavlock, R. Woodrow Setzer et al. · Chemical Research in Toxicology | 8 Mar 2011 | 204 |
| 38 | Ultrasensitive response motifs: basic amplifiers in molecular signalling networks Qiang Zhang, Sudin Bhattacharya, Melvin E. Andersen · Open Biology | Apr 2013 | 202 |
| 39 | PBPK modelling of inter-individual variability in the pharmacokinetics of environmental chemicals Frédéric Y. Bois, Masoud Jamei, Harvey J. Clewell · Toxicology | Jul 2010 | 192 |
| 40 | Arsenic-induced malignant transformation of human keratinocytes: Involvement of Nrf2 Jingbo Pi, Bhalchandra A. Diwan, Yang Sun et al. · Free Radical Biology and Medicine | 4 Jun 2008 | 182 |
| 41 | Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans Alison H. Harrill, Paul Brent Watkins, Stephen V. Su et al. · Genome Research | 5 May 2009 | 179 |
| 42 | Guidelines for the derivation of Biomonitoring Equivalents: Report from the Biomonitoring Equivalents Expert Workshop Sean M. Hays, Lesa L. Aylward, Judy S. LaKind et al. · Regulatory Toxicology and Pharmacology | 24 May 2008 | 178 |
| 43 | IVT-seq reveals extreme bias in RNA sequencing Nicholas F. Lahens, İbrahim Halil Kavaklı, Ray Zhang et al. · Genome biology | 30 Jun 2014 | 175 |
| 44 | Characterization of Deposition from Nasal Spray Devices Using A Computational Fluid Dynamics Model of The Human Nasal Passages Julia S. Kimbell, Rebecca A. Segal, Bahman Asgharian et al. · Journal of Aerosol Medicine | Mar 2007 | 175 |
| 45 | Development and specification of physiologically based pharmacokinetic models for use in risk assessment Rebecca A. Clewell, Harvey J. Clewell · Regulatory Toxicology and Pharmacology | Dec 2007 | 173 |
| 46 | Distribution of DNA Adducts Caused by Inhaled Formaldehyde Is Consistent with Induction of Nasal Carcinoma but Not Leukemia Kun Lü, Leonard B. Collins, Hongyu Ru et al. · Toxicological Sciences | 22 Feb 2010 | 170 |
| 47 | Quantitative in vitro-to-in vivo extrapolation in a high-throughput environment Barbara A. Wetmore · Toxicology | 5 Jun 2014 | 169 |
| 48 | Quantitative Interpretation of Human Biomonitoring Data Harvey J. Clewell, Yu Tan, Jerry L. Campbell et al. · Toxicology and Applied Pharmacology | 5 May 2008 | 169 |
| 49 | Adipose Deficiency of Nrf2 in ob/ob Mice Results in Severe Metabolic Syndrome Peng Xue, Yongyong Hou, Yanyan Chen et al. · Diabetes | 13 Dec 2012 | 168 |
| 50 | Guidelines for the communication of Biomonitoring Equivalents: Report from the Biomonitoring Equivalents Expert Workshop Judy S. LaKind, Lesa L. Aylward, Conrad Brunk et al. · Regulatory Toxicology and Pharmacology | 24 May 2008 | 168 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.