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Institution · Therapure Biopharma (Canada)

Most cited papers from Therapure Biopharma (Canada)

Therapure Biopharma (Canada)

What are the most cited papers from Therapure Biopharma (Canada)?

The most cited paper from Therapure Biopharma (Canada) is "A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmission" (Vernon R. J. Clarke, Barbara A. Ballyk, Ken H. Hoo et al., 1997), with 416 citations. Next come "Kainate receptors are involved in synaptic plasticity" (324) and "Lysophospholipids activate ovarian and breast cancer cells" (285).

Showing 50 of 60 papers. Every paper with more than 22 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmission Vernon R. J. Clarke, Barbara A. Ballyk, Ken H. Hoo et al. · Nature Oct 1997 416
2 Kainate receptors are involved in synaptic plasticity Zuner Assis Bortolotto, Vernon R. J. Clarke, Caroline M. Delany et al. · Nature Open access 18 Nov 1999 324
3 Lysophospholipids activate ovarian and breast cancer cells Yan Juan Xu, X J Fang, Graham Casey et al. · Biochemical Journal Open access Aug 1995 285
4 Regulation of the biological activity of glucagon-like peptide 2 in vivo by dipeptidyl peptidase IV Daniel J. Drucker, Qing Wen Shi, Anna Crivici et al. · Nature Biotechnology Jul 1997 280
5 Calcium‐permeable α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazole propionic acid receptors: A molecular determinant of selective vulnerability in amyotrophic lateral sclerosis Timothy L. Williams, Niki C. Day, Paul G. Ince et al. · Annals of Neurology Aug 1997 216
6 Activity of 2,3-benzodiazepines at Native Rat and Recombinant Human Glutamate Receptors In Vitro : Stereospecificity and Selectivity Profiles David Bleakman, Barbara A. Ballyk, Darryle D. Schoepp et al. · Neuropharmacology Dec 1996 193
7 Time-resolved detection of lanthanide luminescence for ultrasensitive bioanalytical assays Eva F. Gudgin Dickson, Alfred Pollak, Eleftherios P. Diamandis · Journal of Photochemistry and Photobiology B Biology 1995 181
8 Kainate GluR5 receptor subtype mediates the nociceptive response to formalin in the rat Rosa Maria A. Simmons, Dominic L. Li, Ken H. Hoo et al. · Neuropharmacology 1998 172
9 A growing family of receptor genes for lysophosphatidic acid (LPA) and other lysophospholipids (LPs) Jerold J. M. Chun, James J. A. Contos, Donald Gordon Munroe · Cell Biochemistry and Biophysics Jun 1999 154
10 Circulating and Tissue Forms of the Intestinal Growth Factor, Glucagon-Like Peptide-2* Patricia Lee Brubaker, Anna Crivici, Angelo Antonio Izzo et al. · Endocrinology Nov 1997 134
11 Ultrasensitive bioanalytical assays using time-resolved fluorescence detection Eva F. Gudgin Dickson, Alfred Pollak, Eleftherios P. Diamandis · Pharmacology & Therapeutics 1995 133
12 Decahydroisoquinolines: novel competitive AMPA/kainate antagonists with neuroprotective effects in global cerebral ischaemia Michael J. O’Neill, Ann Bond, Paul L. Ornstein et al. · Neuropharmacology Oct 1998 115
13 Characterization of Antiallodynic Actions of ALE-0540, a Novel Nerve Growth Factor Receptor Antagonist, in the Rat Joshua B. Owolabi, Geihan Rizkalla, Ashok Tehim et al. · Journal of Pharmacology and Experimental Therapeutics Jun 1999 105
14 Targeted Ablation of the Murine α-Tropomyosin Gene Edward M. Blanchard, Kenji Iizuka, Michael E. Christe et al. · Circulation Research Dec 1997 104
15 Identification of Glucagon-like Peptide-2 (GLP-2)-activated Signaling Pathways in Baby Hamster Kidney Fibroblasts Expressing the Rat GLP-2 Receptor Bernardo Yusta, Romel Somwar, Feng Wang et al. · Journal of Biological Chemistry Open access Oct 1999 101
16 CRP-ductin: A gene expressed in intestinal crypts and in pancreatic and hepatic ducts Hazel Cheng, Matthew Bjerknes, Hongyun Chen · The Anatomical Record Mar 1996 98
17 Synthesis of Willardiine and 6-Azawillardiine Analogs: Pharmacological Characterization on Cloned Homomeric Human AMPA and Kainate Receptor Subtypes David E. Jane, Ken H. Hoo, Raj Kamboj et al. · Journal of Medicinal Chemistry Open access Oct 1997 96
18 Effect of lysophospholipids on signaling in the human Jurkat T cell line Yan Juan Xu, Graham Casey, G B Mills · Journal of Cellular Physiology Jun 1995 86
19 Localization of residues that confer antibody binding specificity using human chorionic gonadotropin/luteinizing hormone beta subunit chimeras and mutants. William R. Moyle, Martin M. Matzuk, R. Keith Campbell et al. · Journal of Biological Chemistry Open access May 1990 83
20 Critical chemical features in trans-acting-responsive RNA are required for interaction with human immunodeficiency virus type 1 Tat protein Martin Sumner-Smith, Sophie Roy, Richard W. Barnett et al. · Journal of Virology Open access Oct 1991 79
21 A comparison of a direct search method and a genetic algorithm for conformational searching Juan C Meza, Richard Judson, Timothy Robert Faulkner et al. · Journal of Computational Chemistry 15 Jul 1996 62
22 Bioactivation of Nevirapine to a Reactive Quinone Methide: Implications for Liver Injury Amy M. Sharma, Yan Li, Maria Novalen et al. · Chemical Research in Toxicology Open access 13 Jul 2012 62
23 Regulation of IL-6 and the hepatic IL-6 receptor in acute inflammation in vivo M. Geisterfer, Carl D. Richards, Matthias Baumann et al. · Cytokine 1993 60
24 Conformation of parathyroid hormone: time-resolved fluorescence studies Katherine J. Willis, Arthur G. Szabo · Biochemistry 22 Sep 1992 59
25 Animal Models of Idiosyncratic Drug Reactions Winnie Ng, Alexandra R. Lobach, Xu Zhu et al. · Advances in pharmacology Book chapter 2012 58
26 Cloning of a new bidirectionally selectable marker for Aspergillus strains Frank P. Buxton, David I. Gwynne, R. Wayne Davies · Gene Dec 1989 57
27 Molecular Cloning, Expression, and Pharmacological Characterization of humEAA1, a Human Kainate Receptor Subunit Rajender Kumar Kamboj, Darryle D. Schoepp, Stephen L. Nutt et al. · Journal of Neurochemistry Open access 1994 53
28 Structure of human parathyroid hormone(1-34) in the presence of solvents and micelles Lou Anne Strickland, Richard P. Bozzato, K. Anne Kronis · Biochemistry 15 Jun 1993 47
29 LY339434, a GluR5 kainate receptor agonist Ben G. Small, J W Thomas, Mark I. Kemp et al. · Neuropharmacology Oct 1998 45
30 Expression of heterologous proteins in Aspergillus Medha Devchand, David I. Gwynne · Journal of Biotechnology 1991 45
31 Serum corticosterone, interleukin‐1 and tumour necrosis factor in rat experimental endotoxaemia: comparison between Lewis and Wistar strains Mauro Perretti, G S Duncan, R.J. Flower et al. · British Journal of Pharmacology Open access Oct 1993 44
32 Pharmacological characterization of a GluR6 kainate receptor in cultured hippocampal neurons David Bleakman, Ann-Marie Ogden, Paul L. Ornstein et al. · European Journal of Pharmacology Aug 1999 43
33 Distribution of AMPA-selective glutamate receptor subunits in the human hippocampus and cerebellum Nicola C. Day, Timothy L. Williams, Paul G. Ince et al. · Molecular Brain Research Jul 1995 42
34 Molecular characterization of the human EAA5 (GluR7) receptor: a high-affinity kainate receptor with novel potential RNA editing sites. Stephen L. Nutt, Ken H. Hoo, Vikarna Rampersad et al. · PubMed 1994 41
35 Design and synthesis of RNA miniduplexes via a synthetic linker approach Michael Y. X. Ma, Lorne S. Reid, Shane C. Climie et al. · Biochemistry Feb 1993 41
36 C-terminal fragment of parathyroid hormone-related protein, PTHrP-(107-111), stimulates membrane-associated protein kinase C activity and modulates the proliferation of human and murine skin keratinocytes James F. Whitfield, Richard J. Isaacs, Hervé Jouishomme et al. · Journal of Cellular Physiology 1996 39
37 Differential RNA editing efficiency of AMPA receptor subunit GluR-2 in human brain Stephen L. Nutt, Rajender Kumar Kamboj · Neuroreport Aug 1994 39
38 Probing alpha-helical secondary structure at a specific site in model peptides via restriction of tryptophan side-chain rotamer conformation Katherine J. Willis, Witold A. Neugebauer, M. Sikorska et al. · Biophysical Journal Open access May 1994 39
39 Insertion intoAspergillus nidulans of functional UDP-GlcNAc: ?3-d-mannoside ?-1,2-N-acetylglucosaminyltransferase I, the enzyme catalysing the first committed step from oligomannose to hybrid and complex N-glycans Inge Kalsner, William E. A. Hintz, Lorne S. Reid et al. · Glycoconjugate Journal Jun 1995 39
40 Cloning of the genes of the chitin utilization regulon of Serratia liquefaciens Sadhna Joshi, Maya Kozlowski, Ganesh Kumar Selvaraj et al. · Journal of Bacteriology Open access Jul 1988 38
41 Oligodeoxynucleotides containing unnatural L-2′-deoxyribose Masad José Damha, Paul A. Giannaris, Peter S. Marfey et al. · Tetrahedron Letters Jun 1991 37
42 Chitinase and chitobiase production during fermentation of genetically improved Serratia liquefaciens Sadhna Joshi, Maya Kozlowski, Sean Richens et al. · Enzyme and Microbial Technology May 1989 35
43 Molecular structure and pharmacological characterization of humEAA2, a novel human kainate receptor subunit. R. K. Kamboj, Darryle D. Schoepp, Stephen L. Nutt et al. · Molecular Pharmacology Jul 1992 34
44 Design and synthesis of RNA miniduplexes via a synthetic linker approach. 2. Generation of covalently closed, double-stranded cyclic HIV-1 TAR RNA analogs with high Tat-binding affinity Michael Y.-X.Ma, Kirk L. McCallum, Shane C. Climie et al. · Nucleic Acids Research Open access 1993 34
45 Functional expression and pharmacological characterization of the human EAA4 (GluR6) glutamate receptor: a kainate selective channel subunit. Ken H. Hoo, Stephen L. Nutt, Elizabeth J. Fletcher et al. · PubMed 1994 33
46 [3H]ATPA: a high affinity ligand for GluR5 kainate receptors Ken H. Hoo, Beatta Legutko, Geihan Rizkalla et al. · Neuropharmacology Dec 1999 33
47 Restoration of severely depleted femoral trabecular bone in ovariectomized rats by parathyroid hormone-(1?34) James F. Whitfield, Paul Morley, V. Ross et al. · Calcified Tissue International Mar 1995 33
48 Functional Expression of a Recombinant Unitary Glutamate Receptor from Xenopus, Which Contains N-Methyl-D-aspartate (NMDA) and Non-NMDA Receptor Subunits Mikhail M. SOLOVIEV, Matthew J. Brierley, Zuoyi Shao et al. · Journal of Biological Chemistry Open access Dec 1996 32
49 cDNA cloning and functional properties of human glutamate receptor EAA3 (GluR5) in homomeric and heteromeric configuration. Bożena M. Korczak, Stephen L. Nutt, Elizabeth J. Fletcher et al. · PubMed 1995 30
50 Antiherpetic activities of N-alpha-acetyl-nona-D-arginine amide acetate. Martin Sumner-Smith, Yadong Zheng, Y P Zhang et al. · PubMed 1995 29

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.