Institution · Thrombosis Research Institute

Most cited papers from Thrombosis Research Institute

Thrombosis Research Institute

What are the most cited papers from Thrombosis Research Institute?

The most cited paper from Thrombosis Research Institute is "Mutation in blood coagulation factor V associated with resistance to activated protein C" (Rogier M. Bertina, Bobby P. C. Koeleman, Ted Koster et al., 1994), with 3,854 citations. Next come "Prevention of VTE in Orthopedic Surgery Patients" (1,939) and "Venous Thromboembolism Prophylaxis and Treatment in Patients With Cancer: ASCO Clinical Practice Guideline Update" (1,517).

Published TypeFieldAccessAuthorsCitations

Showing 50 of 61 papers. Every paper with more than 353 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Mutation in blood coagulation factor V associated with resistance to activated protein C Rogier M. Bertina, Bobby P. C. Koeleman, Ted Koster et al. · Nature	May 1994	3,854
2	Prevention of VTE in Orthopedic Surgery Patients Yngve T Falck-Ytter, Charles W. Francis, Norman A. Johanson et al. · CHEST Journal	Feb 2012	1,939
3	Venous Thromboembolism Prophylaxis and Treatment in Patients With Cancer: ASCO Clinical Practice Guideline Update Nigel S. Key, Alok A. Khorana, Nicole M. Kuderer et al. · Journal of Clinical Oncology Open access	5 Aug 2019	1,517
4	Venous thromboembolism risk and prophylaxis in the acute hospital care setting (ENDORSE study): a multinational cross-sectional study Alexander T. Cohen, Victor F. Tapson, Jean‐François Bergmann et al. · The Lancet Open access	Feb 2008	1,510
5	Rivaroxaban versus Enoxaparin for Thromboprophylaxis after Hip Arthroplasty Bengt I. Eriksson, Lars C. Borris, Richard Joel Friedman et al. · New England Journal of Medicine Open access	25 Jun 2008	1,440
6	The mutational spectrum of single base-pair substitutions in mRNA splice junctions of human genes: Causes and consequences Michael Krawczak, Jochen Reiss, D.N. Cooper · Human Genetics	Sep 1992	1,359
7	Targeted Deficiency or Cytosolic Truncation of the VE-cadherin Gene in Mice Impairs VEGF-Mediated Endothelial Survival and Angiogenesis Peter Carmeliet et al. · Cell Open access	Jul 1999	1,295
8	Update of the guidelines for lupus anticoagulant detection Vittorio Pengo, Armando Tripodi, Guido Reber et al. · Journal of Thrombosis and Haemostasis Open access	17 Jul 2009	1,206
9	Role of clotting factor VIII in effect of von Willebrand factor on occurrence of deep-vein thrombosis Ted Koster, Jan Paul Vandenbroucke, Frits R. Rosendaal et al. · The Lancet	1995	1,142
10	Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: a randomised, double-blind, non-inferiority trial Bengt I. Eriksson, Ola Einar Dahl, Nadia Rosencher et al. · The Lancet	Sep 2007	1,120
11	Extended duration rivaroxaban versus short-term enoxaparin for the prevention of venous thromboembolism after total hip arthroplasty: a double-blind, randomised controlled trial Ajay K. Kakkar, Benjamin Brenner, Ola Einar Dahl et al. · The Lancet Open access	25 Jun 2008	1,073
12	Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration Bert Oosthuyse et al. · Nature Genetics	Jun 2001	1,016
13	Tissue-factor–bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation Ian Del Conde, Corie N. Shrimpton, Perumal Thiagarajan et al. · Blood Open access	2 Mar 2005	1,010
14	Oral dabigatran etexilate vs. subcutaneous enoxaparin for the prevention of venous thromboembolism after total knee replacement: the RE‐MODEL randomized trial Bengt I. Eriksson, O.E. Dahl, Nadia Rosencher et al. · Journal of Thrombosis and Haemostasis Open access	19 Oct 2007	985
15	Treatment of Acute Venous Thromboembolism With Dabigatran or Warfarin and Pooled Analysis Sam Schulman, Ajay K. Kakkar, Samuel Zachary Goldhaber et al. · Circulation Open access	16 Dec 2013	936
16	Optimal Oral Anticoagulant Therapy in Patients with Mechanical Heart Valves Suzanne C. Cannegieter, Frits R. Rosendaal, Axel R. Wintzen et al. · New England Journal of Medicine Open access	6 Jul 1995	914
17	Rivaroxaban with or without aspirin in patients with stable peripheral or carotid artery disease: an international, randomised, double-blind, placebo-controlled trial Sonia S. Anand et al. · The Lancet Open access644 authors	10 Nov 2017	892
18	Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche Andrew T. Chow, Daniel Lucas, Andrés Hidalgo et al. · The Journal of Experimental Medicine Open access	31 Jan 2011	867
19	Rivaroxaban vs warfarin in high-risk patients with antiphospholipid syndrome Vittorio Pengo et al. · Blood Open access	12 Jul 2018	821
20	Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure Stephane R B Heymans et al. · Nature Medicine	Oct 1999	801
21	Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188 Peter Carmeliet, Yin‐Shan Ng, Dieter Nuyens et al. · Nature Medicine	May 1999	685
22	Urokinase-generated plasmin activates matrix metalloproteinases during aneurysm formation Peter Carmeliet, Lieve Moons, Roger H Lijnen et al. · Nature Genetics	Dec 1997	669
23	2019 international clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer Dominique Farge et al. · The Lancet Oncology Open access	3 Sep 2019	660
24	Meta-analysis of low molecular weight heparin in the prevention of venous thromboembolism in general surgery Patrick Mismetti, Silvy Laporte, J-Y Darmon et al. · British journal of surgery Review	Jul 2001	651
25	International clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer Dominique Farge et al. · Journal of Thrombosis and Haemostasis Open access	11 Dec 2012	596
26	P-selectin induces the expression of tissue factor on monocytes. Alessandro Celi, G. Pellegrini, Roberto Lorenzet et al. · Proceedings of the National Academy of Sciences Open access	13 Sep 1994	594
27	Effects of inflammatory cytokines on the release and cleavage of the endothelial cell–derived ultralarge von Willebrand factor multimers under flow Aubrey Bernardo, Chalmette Ball, Leticia H. Nolasco et al. · Blood Open access	22 Mar 2004	592
28	Enhancement by factor V Leiden mutation of risk of deep-vein thrombosis associated with oral contraceptives containing a third-generation progestagen Kitty W. M. Bloemenkamp, Frans M. Helmerhorst, F. R. Rosendaal et al. · The Lancet	Dec 1995	591
29	Central role of the P2Y12 receptor in platelet activation Robert T. Dorsam, Satya P. Kunapuli · Journal of Clinical Investigation	Feb 2004	578
30	Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost effectiveness analysis José A López-López, Jonathan A C Sterne, Howard H. Z. Thom et al. · BMJ ReviewOpen access	28 Nov 2017	561
31	ARTERIAL THROMBOSIS, INTRAUTERINE DEATH AND "LUPUS" ANTICOAGULANT: DETECTION OF IMMUNOGLOBULIN INTERFERING WITH PROSTACYCLIN FORMATION LuisO. Carreras, S.J. Machin, Rene Deman et al. · The Lancet	1981	554
32	PADGEM (GMP140) is a component of Weibel-Palade bodies of human endothelial cells Roberta Bonfanti, BC Furie, Bruce Furie et al. · Blood	Apr 1989	547
33	Molecular and Cellular Biology of Blood Coagulation Jeffrey S. Flier, Lisa H. Underhill, Bruce Furie et al. · New England Journal of Medicine	19 Mar 1992	535
34	Pregnancy Loss in the Antiphospholipid-Antibody Syndrome — A Possible Thrombogenic Mechanism Jacob H. Rand, Xiao-Xuan Wu, Harry A.M. Andree et al. · New England Journal of Medicine Open access	17 Jul 1997	529
35	Von Willebrand factor, platelets and endothelial cell interactions Zaverio M. Ruggeri · Journal of Thrombosis and Haemostasis Open access	20 Jun 2003	490
36	Thrombosis: a major contributor to the global disease burden Gary E. Raskob, Pantep Angchaisuksiri, Alicia Noemí Blanco et al. · Journal of Thrombosis and Haemostasis Open access	Oct 2014	488
37	Gene deletions causing human genetic disease: mechanisms of mutagenesis and the role of the local DNA sequence environment Michael Krawczak, D.N. Cooper · Human Genetics	Mar 1991	486
38	Safety of Proton Pump Inhibitors Based on a Large, Multi-Year, Randomized Trial of Patients Receiving Rivaroxaban or Aspirin Paul Moayyedi et al. · Gastroenterology Open access	29 May 2019	484
39	2022 international clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer, including patients with COVID-19 Dominique Farge et al. · The Lancet Oncology Open access106 authors	27 Jun 2022	478
40	Risk Profiles and Antithrombotic Treatment of Patients Newly Diagnosed with Atrial Fibrillation at Risk of Stroke: Perspectives from the International, Observational, Prospective GARFIELD Registry Ajay K. Kakkar, Iris Mueller, Jean‐Pierre Bassand et al. · PLoS ONE Open access	21 May 2013	448
41	Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis Anne Angelillo‐Scherrer, Pablo Garcı́a de Frutos, Cristina García Aparicio et al. · Nature Medicine Open access	Feb 2001	439
42	Self-complementary adeno-associated virus vectors containing a novel liver-specific human factor IX expression cassette enable highly efficient transduction of murine and nonhuman primate liver Amit C. Nathwani, John T. Gray, Catherine Y. Ng et al. · Blood Open access	2 Dec 2005	428
43	Secreted Frizzled‐related proteins: searching for relationships and patterns Steve E. Jones, Catherine Jomary · BioEssays Review	22 Aug 2002	428
44	Human CD56bright NK Cells: An Update Tatiana Michel, Aurélie Poli, Angélica Cuapio et al. · The Journal of Immunology	19 Mar 2016	424
45	von Willebrand factor Zaverio M. Ruggeri, Jerry L. Ware · The FASEB Journal	Feb 1993	423
46	Palladacycles − An Old Organometallic Family Revisited: New, Simple, and Efficient Catalyst Precursors for Homogeneous Catalysis Jaı̈rton Dupont, Michel Pfeffer, John A. Spencer · European Journal of Inorganic Chemistry	Aug 2001	422
47	Ionic liquid-based aqueous two-phase extraction of selected proteins Yuanchao Pei, Jianji Wang, Kun Wu et al. · Separation and Purification Technology	18 Oct 2008	419
48	Activation-independent platelet adhesion and aggregation under elevated shear stress Zaverio M. Ruggeri, Jennifer Nagrampa Orje, Rolf Habermann et al. · Blood Open access	14 Jun 2006	416
49	Oral dabigatran versus enoxaparin for thromboprophylaxis after primary total hip arthroplasty (RE-NOVATE II) Ola Dahl, Michael H. Huo, Andreas Alois Kurth et al. · Thrombosis and Haemostasis	2011	401
50	Bcl-2 family proteins: regulators of apoptosis and chemoresistance in hematologic malignancies. V V Kakkar · PubMed	Oct 1997	399

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.