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Most cited papers from Tissue Genetics (United States)

What are the most cited papers from Tissue Genetics (United States)?

The most cited paper from Tissue Genetics (United States) is "Novel Regulators of Bone Formation: Molecular Clones and Activities" (John M. Wozney, Vicki Rosen, Anthony J. Celeste et al., 1988), with 3,927 citations. Next come "The interaction of α2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism" (1,065) and "L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L" (1,031).

Showing 50 of 61 papers. Every paper with more than 161 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Novel Regulators of Bone Formation: Molecular Clones and Activities John M. Wozney, Vicki Rosen, Anthony J. Celeste et al. · Science 16 Dec 1988 3,927
2 The interaction of α2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism A. John Barrett, P M Starkey · Biochemical Journal Open access Aug 1973 1,065
3 L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L A. John Barrett, A A Kembhavi, Molly A. Brown et al. · Biochemical Journal Open access 1982 1,031
4 Polygenic susceptibility to breast cancer and implications for prevention Paul D.P. Pharoah, Antonis C. Antoniou, Martin Bobrow et al. · Nature Genetics 4 Mar 2002 907
5 [13] Evolutionary families of metallopeptidases Neil David Rawlings, A. John Barrett · Methods in enzymology on CD-ROM/Methods in enzymology Book chapter 1995 813
6 Synergistic Roles of Bone Morphogenetic Protein 15 and Growth Differentiation Factor 9 in Ovarian Function Changning Yan, Pei Wang, Janet L. DeMayo et al. · Molecular Endocrinology Jun 2001 805
7 PPAR γ insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors Toru Akune, Shinsuke Ohba, Satoru Kamekura et al. · Journal of Clinical Investigation Open access 15 Mar 2004 786
8 Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity Andrew Docherty, Alan Lyons, Bryan John Smith et al. · Nature Nov 1985 696
9 Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1 / 2 (CIMBA) Nasim Mavaddat et al. · Cancer Epidemiology Biomarkers & Prevention Open access133 authors 2012 673
10 Purification and characterization of other distinct bone-inducing factors. E A Wang, Vicki Rosen, Paul Cordes et al. · Proceedings of the National Academy of Sciences Open access Dec 1988 620
11 The Soluble Catalytic Domain of Membrane Type 1 Matrix Metalloproteinase Cleaves the Propeptide of Progelatinase A and Initiates Autoproteolytic Activation Horst Günter Will, Susan J. Atkinson, Georgina S. Butler et al. · Journal of Biological Chemistry Open access Jul 1996 571
12 Secretion of metalloproteinases by stimulated capillary endothelial cells. II. Expression of collagenase and stromelysin activities is regulated by endogenous inhibitors. G. Scott Herron, Michael J. Banda, E J Clark et al. · Journal of Biological Chemistry Open access Feb 1986 525
13 The Bone Morphogenetic Protein 15 Gene Is X-Linked and Expressed in Oocytes Jennifer L. Dube, Pei Wang, Julia Andrea Elvin et al. · Molecular Endocrinology Dec 1998 499
14 Stromelysin, a connective tissue-degrading metalloendopeptidase secreted by stimulated rabbit synovial fibroblasts in parallel with collagenase. Biosynthesis, isolation, characterization, and substrates. Jennie R. Chin, Gillian Murphy, Zena Werb · Journal of Biological Chemistry Open access Oct 1985 498
15 Matrix metalloproteinase degradation of elastin, type IV collagen and proteoglycan. A quantitative comparison of the activities of 95 kDa and 72 kDa gelatinases, stromelysins-1 and -2 and punctuated metalloproteinase (PUMP) Gillian Murphy, Mark I. Cockett, Robin V. Ward et al. · Biochemical Journal Open access Jul 1991 456
16 Comparison of human stromelysin and collagenase by cloning and sequence analysis S. E. Whitham, Gillian Murphy, Peter E. Angel et al. · Biochemical Journal Open access 15 Dec 1986 441
17 Cell to substratum contacts of chick fibroblasts and their relation to the microfilament system. a correlated interference-reflexion and high-voltage electron-microscope study Julian P. Heath, Graham Dunn · Journal of Cell Science Feb 1978 414
18 Dose-Response Association of CD8 + Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer Ellen L. Goode et al. · JAMA Oncology Open access 19 Oct 2017 411
19 Cathepsin B1. A lysosomal enzyme that degrades native collagen Mary C. Burleigh, A. John Barrett, Gerald S. Lazarus · Biochemical Journal Open access Feb 1974 406
20 Xanthene-dye-labelled phosphatidylethanolamines as probes of interfacial pH. Studies in phospholipid vesicles Christopher G. Knight, Thomas C. Stephens · Biochemical Journal Open access 15 Mar 1989 401
21 Shortened Telomere Length Is Associated with Increased Risk of Cancer: A Meta-Analysis Hongxia Ma, Ziyuan Zhou, Sheng Wei et al. · PLoS ONE ReviewOpen access 10 Jun 2011 380
22 The N-terminal domain of tissue inhibitor of metalloproteinases retains metalloproteinase inhibitory activity GILLIAN M. MURPHY, Annick Houbrechts, Mark I. Cockett et al. · Biochemistry Aug 1991 324
23 Human cathepsin B1. Purification and some properties of the enzyme A. John Barrett · Biochemical Journal Open access Apr 1973 324
24 Integrin α2β1-independent activation of platelets by simple collagen-like peptides: collagen tertiary (triple-helical) and quaternary (polymeric) structures are sufficient alone for α2β1-independent platelet reactivity L F Morton, Philip G. Hargreaves, Richard W. Farndale et al. · Biochemical Journal Open access Mar 1995 322
25 [1] Classification of peptidases A. John Barrett · Methods in enzymology on CD-ROM/Methods in enzymology Book chapter 1994 297
26 Cathepsin D. Purification of isoenzymes from human and chicken liver A. John Barrett · Biochemical Journal Open access Apr 1970 271
27 The C-terminal domain of 72 kDa gelatinase A is not required for catalysis, but is essential for membrane activation and modulates interactions with tissue inhibitors of metalloproteinases Gillian Murphy, Frances W. Willenbrock, Robin V. Ward et al. · Biochemical Journal Open access May 1992 266
28 Pig catabolin is a form of interleukin 1. Cartilage and bone resorb, fibroblasts make prostaglandin and collagenase, and thymocyte proliferation is augmented in response to one protein Jeremy Saklatvala, L M C Pilsworth, Simon J. Sarsfield et al. · Biochemical Journal Open access Dec 1984 261
29 The Croonian Lecture, 1978 - The crawling movement of metazoan cells Michael Abercrombie · Proceedings of the Royal Society B Biological Sciences 29 Feb 1980 256
30 DNA repair polymorphisms and cancer risk in non-smokers in a cohort study Giuseppe Matullo et al. · Carcinogenesis Open access 23 Nov 2005 247
31 EFFECT OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS ON THE COURSE OF OSTEOARTHRITIS Shawky Rashad, Anne Hemingway, Kim Drummond Rainsford et al. · The Lancet Sep 1989 238
32 Characterization of gelatinase from pig polymorphonuclear leucocytes. A metalloproteinase resembling tumour type IV collagenase Gillian Murphy, Rebecca Mary Ward, Rosalind M. Hembry et al. · Biochemical Journal Open access Mar 1989 228
33 Families and Clans of Serine Peptidases A. John Barrett, Neil David Rawlings · Archives of Biochemistry and Biophysics Apr 1995 228
34 Natriuretic peptides and integrated risk assessment for cardiovascular disease: an individual-participant-data meta-analysis Peter Willeit et al. · The Lancet Diabetes & Endocrinology ReviewOpen access 6 Sep 2016 226
35 Evidence that latent collagenases are enzyme-inhibitor complexes Anthony Sellers, Elizabeth J. Cartwright, GILLIAN M. MURPHY et al. · Biochemical Journal Open access May 1977 223
36 The cysteine proteinases of the pineapple plant. Andrew D. Rowan, David J. Buttle, A. John Barrett · PubMed Open access 15 Mar 1990 211
37 The two types of nucleoproteins during mitosis W. Jacobson, Michael Webb · Experimental Cell Research 1952 210
38 Protection by zinc against cadmium toxicity Michael Webb · Biochemical Pharmacology Oct 1972 209
39 Human hepatic lipocytes synthesize tissue inhibitor of metalloproteinases-1. Implications for regulation of matrix degradation in liver. John Peter Iredale, Gillian Murphy, Rosalind M. Hembry et al. · Journal of Clinical Investigation Open access Jul 1992 207
40 Plasma Membrane Synthesis in the Macrophage following Phagocytosis of Polystyrene Latex Particles Zena Werb, Zanvil A. Cohn · Journal of Biological Chemistry Open access Apr 1972 207
41 Analysis of protein and peptide mixtures Andrew F. Bury · Journal of Chromatography A Sep 1981 207
42 The interaction of α2-macroglobulin with proteinases. Binding and inhibition of mammalian collagenases and other metal proteinases Zena Werb, Mary C. Burleigh, A. John Barrett et al. · Biochemical Journal Open access May 1974 203
43 CA074 methyl ester: A proinhibitor for intracellular cathepsin B David J. Buttle, Mitsuo Murata, Christopher G. Knight et al. · Archives of Biochemistry and Biophysics Dec 1992 201
44 Partial purification of collagenase and gelatinase from human polymorphonuclear leucocytes. Analysis of their actions on soluble and insoluble collagens Gillian Murphy, John J. Reynolds, Ursula Bretz et al. · Biochemical Journal Open access Apr 1982 199
45 Purification and characterization of a bone metalloproteinase that degrades gelatin and types IV and V collagen Gillian Murphy, Christine G. McAlpine, Christopher T. Poll et al. · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology Sep 1985 196
46 Pig interleukin 1. Purification of two immunologically different leukocyte proteins that cause cartilage resorption, lymphocyte activation, and fever. Jeremy Saklatvala, Simon J. Sarsfield, Yvonne Townsend · The Journal of Experimental Medicine Open access Oct 1985 194
47 OSTEOGENESIS IMPERFECTA Ian Dickson · The Lancet 1976 189
48 The Two Cysteine Endopeptidases of Legume Seeds: Purification and Characterization by Use of Specific Fluorometric Assays A A Kembhavi, David J. Buttle, Christopher G. Knight et al. · Archives of Biochemistry and Biophysics Jun 1993 186
49 Elastinolytic activity of human cathepsin L Robert W. Mason, David A. Johnson, A. John Barrett et al. · Biochemical Journal Open access Feb 1986 185
50 The degradation of articular collagen by neutrophil proteinases P M Starkey, A. John Barrett, Mary C. Burleigh · Biochimica et Biophysica Acta (BBA) - Enzymology Aug 1977 185

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.