| 1 |
Novel Regulators of Bone Formation: Molecular Clones and Activities
John M. Wozney, Vicki Rosen, Anthony J. Celeste et al. · Science
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16 Dec 1988 |
3,927 |
| 2 |
The interaction of α2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism
A. John Barrett, P M Starkey · Biochemical Journal
Open access |
Aug 1973 |
1,065 |
| 3 |
L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L
A. John Barrett, A A Kembhavi, Molly A. Brown et al. · Biochemical Journal
Open access |
1982 |
1,031 |
| 4 |
Polygenic susceptibility to breast cancer and implications for prevention
Paul D.P. Pharoah, Antonis C. Antoniou, Martin Bobrow et al. · Nature Genetics
|
4 Mar 2002 |
907 |
| 5 |
[13] Evolutionary families of metallopeptidases
Neil David Rawlings, A. John Barrett · Methods in enzymology on CD-ROM/Methods in enzymology
Book chapter |
1995 |
813 |
| 6 |
Synergistic Roles of Bone Morphogenetic Protein 15 and Growth Differentiation Factor 9 in Ovarian Function
Changning Yan, Pei Wang, Janet L. DeMayo et al. · Molecular Endocrinology
|
Jun 2001 |
805 |
| 7 |
PPAR γ insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors
Toru Akune, Shinsuke Ohba, Satoru Kamekura et al. · Journal of Clinical Investigation
Open access |
15 Mar 2004 |
786 |
| 8 |
Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity
Andrew Docherty, Alan Lyons, Bryan John Smith et al. · Nature
|
Nov 1985 |
696 |
| 9 |
Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1 / 2 (CIMBA)
Nasim Mavaddat et al. · Cancer Epidemiology Biomarkers & Prevention
Open access133 authors |
2012 |
673 |
| 10 |
Purification and characterization of other distinct bone-inducing factors.
E A Wang, Vicki Rosen, Paul Cordes et al. · Proceedings of the National Academy of Sciences
Open access |
Dec 1988 |
620 |
| 11 |
The Soluble Catalytic Domain of Membrane Type 1 Matrix Metalloproteinase Cleaves the Propeptide of Progelatinase A and Initiates Autoproteolytic Activation
Horst Günter Will, Susan J. Atkinson, Georgina S. Butler et al. · Journal of Biological Chemistry
Open access |
Jul 1996 |
571 |
| 12 |
Secretion of metalloproteinases by stimulated capillary endothelial cells. II. Expression of collagenase and stromelysin activities is regulated by endogenous inhibitors.
G. Scott Herron, Michael J. Banda, E J Clark et al. · Journal of Biological Chemistry
Open access |
Feb 1986 |
525 |
| 13 |
The Bone Morphogenetic Protein 15 Gene Is X-Linked and Expressed in Oocytes
Jennifer L. Dube, Pei Wang, Julia Andrea Elvin et al. · Molecular Endocrinology
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Dec 1998 |
499 |
| 14 |
Stromelysin, a connective tissue-degrading metalloendopeptidase secreted by stimulated rabbit synovial fibroblasts in parallel with collagenase. Biosynthesis, isolation, characterization, and substrates.
Jennie R. Chin, Gillian Murphy, Zena Werb · Journal of Biological Chemistry
Open access |
Oct 1985 |
498 |
| 15 |
Matrix metalloproteinase degradation of elastin, type IV collagen and proteoglycan. A quantitative comparison of the activities of 95 kDa and 72 kDa gelatinases, stromelysins-1 and -2 and punctuated metalloproteinase (PUMP)
Gillian Murphy, Mark I. Cockett, Robin V. Ward et al. · Biochemical Journal
Open access |
Jul 1991 |
456 |
| 16 |
Comparison of human stromelysin and collagenase by cloning and sequence analysis
S. E. Whitham, Gillian Murphy, Peter E. Angel et al. · Biochemical Journal
Open access |
15 Dec 1986 |
441 |
| 17 |
Cell to substratum contacts of chick fibroblasts and their relation to the microfilament system. a correlated interference-reflexion and high-voltage electron-microscope study
Julian P. Heath, Graham Dunn · Journal of Cell Science
|
Feb 1978 |
414 |
| 18 |
Dose-Response Association of CD8 + Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer
Ellen L. Goode et al. · JAMA Oncology
Open access |
19 Oct 2017 |
411 |
| 19 |
Cathepsin B1. A lysosomal enzyme that degrades native collagen
Mary C. Burleigh, A. John Barrett, Gerald S. Lazarus · Biochemical Journal
Open access |
Feb 1974 |
406 |
| 20 |
Xanthene-dye-labelled phosphatidylethanolamines as probes of interfacial pH. Studies in phospholipid vesicles
Christopher G. Knight, Thomas C. Stephens · Biochemical Journal
Open access |
15 Mar 1989 |
401 |
| 21 |
Shortened Telomere Length Is Associated with Increased Risk of Cancer: A Meta-Analysis
Hongxia Ma, Ziyuan Zhou, Sheng Wei et al. · PLoS ONE
ReviewOpen access |
10 Jun 2011 |
380 |
| 22 |
The N-terminal domain of tissue inhibitor of metalloproteinases retains metalloproteinase inhibitory activity
GILLIAN M. MURPHY, Annick Houbrechts, Mark I. Cockett et al. · Biochemistry
|
Aug 1991 |
324 |
| 23 |
Human cathepsin B1. Purification and some properties of the enzyme
A. John Barrett · Biochemical Journal
Open access |
Apr 1973 |
324 |
| 24 |
Integrin α2β1-independent activation of platelets by simple collagen-like peptides: collagen tertiary (triple-helical) and quaternary (polymeric) structures are sufficient alone for α2β1-independent platelet reactivity
L F Morton, Philip G. Hargreaves, Richard W. Farndale et al. · Biochemical Journal
Open access |
Mar 1995 |
322 |
| 25 |
[1] Classification of peptidases
A. John Barrett · Methods in enzymology on CD-ROM/Methods in enzymology
Book chapter |
1994 |
297 |
| 26 |
Cathepsin D. Purification of isoenzymes from human and chicken liver
A. John Barrett · Biochemical Journal
Open access |
Apr 1970 |
271 |
| 27 |
The C-terminal domain of 72 kDa gelatinase A is not required for catalysis, but is essential for membrane activation and modulates interactions with tissue inhibitors of metalloproteinases
Gillian Murphy, Frances W. Willenbrock, Robin V. Ward et al. · Biochemical Journal
Open access |
May 1992 |
266 |
| 28 |
Pig catabolin is a form of interleukin 1. Cartilage and bone resorb, fibroblasts make prostaglandin and collagenase, and thymocyte proliferation is augmented in response to one protein
Jeremy Saklatvala, L M C Pilsworth, Simon J. Sarsfield et al. · Biochemical Journal
Open access |
Dec 1984 |
261 |
| 29 |
The Croonian Lecture, 1978 - The crawling movement of metazoan cells
Michael Abercrombie · Proceedings of the Royal Society B Biological Sciences
|
29 Feb 1980 |
256 |
| 30 |
DNA repair polymorphisms and cancer risk in non-smokers in a cohort study
Giuseppe Matullo et al. · Carcinogenesis
Open access |
23 Nov 2005 |
247 |
| 31 |
EFFECT OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS ON THE COURSE OF OSTEOARTHRITIS
Shawky Rashad, Anne Hemingway, Kim Drummond Rainsford et al. · The Lancet
|
Sep 1989 |
238 |
| 32 |
Characterization of gelatinase from pig polymorphonuclear leucocytes. A metalloproteinase resembling tumour type IV collagenase
Gillian Murphy, Rebecca Mary Ward, Rosalind M. Hembry et al. · Biochemical Journal
Open access |
Mar 1989 |
228 |
| 33 |
Families and Clans of Serine Peptidases
A. John Barrett, Neil David Rawlings · Archives of Biochemistry and Biophysics
|
Apr 1995 |
228 |
| 34 |
Natriuretic peptides and integrated risk assessment for cardiovascular disease: an individual-participant-data meta-analysis
Peter Willeit et al. · The Lancet Diabetes & Endocrinology
ReviewOpen access |
6 Sep 2016 |
226 |
| 35 |
Evidence that latent collagenases are enzyme-inhibitor complexes
Anthony Sellers, Elizabeth J. Cartwright, GILLIAN M. MURPHY et al. · Biochemical Journal
Open access |
May 1977 |
223 |
| 36 |
The cysteine proteinases of the pineapple plant.
Andrew D. Rowan, David J. Buttle, A. John Barrett · PubMed
Open access |
15 Mar 1990 |
211 |
| 37 |
The two types of nucleoproteins during mitosis
W. Jacobson, Michael Webb · Experimental Cell Research
|
1952 |
210 |
| 38 |
Protection by zinc against cadmium toxicity
Michael Webb · Biochemical Pharmacology
|
Oct 1972 |
209 |
| 39 |
Human hepatic lipocytes synthesize tissue inhibitor of metalloproteinases-1. Implications for regulation of matrix degradation in liver.
John Peter Iredale, Gillian Murphy, Rosalind M. Hembry et al. · Journal of Clinical Investigation
Open access |
Jul 1992 |
207 |
| 40 |
Plasma Membrane Synthesis in the Macrophage following Phagocytosis of Polystyrene Latex Particles
Zena Werb, Zanvil A. Cohn · Journal of Biological Chemistry
Open access |
Apr 1972 |
207 |
| 41 |
Analysis of protein and peptide mixtures
Andrew F. Bury · Journal of Chromatography A
|
Sep 1981 |
207 |
| 42 |
The interaction of α2-macroglobulin with proteinases. Binding and inhibition of mammalian collagenases and other metal proteinases
Zena Werb, Mary C. Burleigh, A. John Barrett et al. · Biochemical Journal
Open access |
May 1974 |
203 |
| 43 |
CA074 methyl ester: A proinhibitor for intracellular cathepsin B
David J. Buttle, Mitsuo Murata, Christopher G. Knight et al. · Archives of Biochemistry and Biophysics
|
Dec 1992 |
201 |
| 44 |
Partial purification of collagenase and gelatinase from human polymorphonuclear leucocytes. Analysis of their actions on soluble and insoluble collagens
Gillian Murphy, John J. Reynolds, Ursula Bretz et al. · Biochemical Journal
Open access |
Apr 1982 |
199 |
| 45 |
Purification and characterization of a bone metalloproteinase that degrades gelatin and types IV and V collagen
Gillian Murphy, Christine G. McAlpine, Christopher T. Poll et al. · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology
|
Sep 1985 |
196 |
| 46 |
Pig interleukin 1. Purification of two immunologically different leukocyte proteins that cause cartilage resorption, lymphocyte activation, and fever.
Jeremy Saklatvala, Simon J. Sarsfield, Yvonne Townsend · The Journal of Experimental Medicine
Open access |
Oct 1985 |
194 |
| 47 |
OSTEOGENESIS IMPERFECTA
Ian Dickson · The Lancet
|
1976 |
189 |
| 48 |
The Two Cysteine Endopeptidases of Legume Seeds: Purification and Characterization by Use of Specific Fluorometric Assays
A A Kembhavi, David J. Buttle, Christopher G. Knight et al. · Archives of Biochemistry and Biophysics
|
Jun 1993 |
186 |
| 49 |
Elastinolytic activity of human cathepsin L
Robert W. Mason, David A. Johnson, A. John Barrett et al. · Biochemical Journal
Open access |
Feb 1986 |
185 |
| 50 |
The degradation of articular collagen by neutrophil proteinases
P M Starkey, A. John Barrett, Mary C. Burleigh · Biochimica et Biophysica Acta (BBA) - Enzymology
|
Aug 1977 |
185 |