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Most cited papers from Turku Centre for Biotechnology

What are the most cited papers from Turku Centre for Biotechnology?

The most cited paper from Turku Centre for Biotechnology is "Breaking the diffraction resolution limit by stimulated emission: stimulated-emission-depletion fluorescence microscopy" (Stefan W. Hell, Jan Wichmann, 1994), with 6,210 citations. Next come "A survey of best practices for RNA-seq data analysis" (2,977) and "Human gut microbes impact host serum metabolome and insulin sensitivity" (2,204).

Showing 50 of 61 papers. Every paper with more than 333 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Breaking the diffraction resolution limit by stimulated emission: stimulated-emission-depletion fluorescence microscopy Stefan W. Hell, Jan Wichmann · Optics Letters Jun 1994 6,210
2 A survey of best practices for RNA-seq data analysis Ana Conesa, Pedro Madrigal, Sonia Tarazona et al. · Genome biology Open access 26 Jan 2016 2,977
3 Human gut microbes impact host serum metabolome and insulin sensitivity Helle Pedersen et al. · Nature Open access Jul 2016 2,204
4 Every step of the way: integrins in cancer progression and metastasis Hellyeh Hamidi, Johanna Ivaska · Nature reviews. Cancer ReviewOpen access 12 Jul 2018 1,563
5 Exosomes with Immune Modulatory Features Are Present in Human Breast Milk Charlotte Admyre, Sara M. Johansson, Khaleda Rahman Qazi et al. · The Journal of Immunology Open access Aug 2007 1,248
6 A practical guide to single-cell RNA-sequencing for biomedical research and clinical applications Ashraful Haque, Jessica A. Engel, Sarah Amalia Teichmann et al. · Genome Medicine Open access 18 Aug 2017 1,168
7 Roles of the heat shock transcription factors in regulation of the heat shock response and beyond Lila Pirkkala, Päivi Nykänen, Lea Sistonen · The FASEB Journal May 2001 1,017
8 Copy number variation and selection during reprogramming to pluripotency Samer M. I. Hussein, Nizar N. Batada, Sanna Vuoristo et al. · Nature Mar 2011 961
9 Europium as a label in time-resolved immunofluorometric assays Ilkka A. Hemmilä, S. Dakubu, Veli-Matti Mukkala et al. · Analytical Biochemistry Mar 1984 850
10 MZmine: toolbox for processing and visualization of mass spectrometry based molecular profile data Mikko Katajamaa, Jarkko Miettinen, Matej Orešič · Bioinformatics 10 Jan 2006 835
11 Phosphatase‐mediated crosstalk between MAPK signaling pathways in the regulation of cell survival Melissa R. Junttila, Song‐Ping Li, Jukka K. Westermarck · The FASEB Journal 26 Nov 2007 825
12 Novel functions of vimentin in cell adhesion, migration, and signaling Johanna Ivaska, Hanna‐Mari Pallari, Jonna Nevo et al. · Experimental Cell Research 15 Apr 2007 803
13 Tet1 and Tet2 Regulate 5-Hydroxymethylcytosine Production and Cell Lineage Specification in Mouse Embryonic Stem Cells Kian Peng Koh, Akiko Yabuuchi, Sridhar Rao et al. · Cell stem cell Open access Feb 2011 797
14 ColonyArea: An ImageJ Plugin to Automatically Quantify Colony Formation in Clonogenic Assays Camilo Guzmán, Manish Bagga, Amanpreet Kaur et al. · PLoS ONE Open access 19 Mar 2014 783
15 Stress-Inducible Regulation of Heat Shock Factor 1 by the Deacetylase SIRT1 Sandy D. Westerheide, Julius Anckar, Stanley M. Stevens et al. · Science Open access 19 Feb 2009 731
16 Mesoporous silica nanoparticles in medicine—Recent advances Veronika Mamaeva, Cecilia Sahlgren, Mika Lindén · Advanced Drug Delivery Reviews Review 17 Aug 2012 704
17 The reinterpretation of dreams: An evolutionary hypothesis of the function of dreaming Antti Revonsuo · Behavioral and Brain Sciences Dec 2000 680
18 Association of Gestational Weight Gain With Adverse Maternal and Infant Outcomes LifeCycle Project-Maternal Obesity and Childhood Outcomes Study Group et al. · JAMA Open access 7 May 2019 661
19 Vimentin regulates EMT induction by Slug and oncogenic H-Ras and migration by governing Axl expression in breast cancer Karoliina Vuoriluoto, Hallvard Haugen, Santeri Kiviluoto et al. · Oncogene 8 Nov 2010 652
20 Serum Prostate Specific Antigen Complexed toα1-Antichymotrypsin as an Indicator of Prostate Cancer Anders G. Christensson, Thomas Björk, Olle Nilsson et al. · The Journal of Urology Jul 1993 650
21 Matrix metalloproteinases in cancer: Prognostic markers and therapeutic targets Pia Vihinen, Veli‐Matti Kähäri · International Journal of Cancer Open access 11 Apr 2002 641
22 Metabolomics enables precision medicine: “A White Paper, Community Perspective” for “Precision Medicine and Pharmacometabolomics Task Group”-Metabolomics Societ, Richard D. Beger, Warwick B. Dunn et al. · Metabolomics Open access Sep 2016 624
23 Data processing for mass spectrometry-based metabolomics Mikko Katajamaa, Matej Orešič · Journal of Chromatography A 20 Apr 2007 610
24 Impact of maternal body mass index and gestational weight gain on pregnancy complications: an individual participant data meta‐analysis of European, North American and Australian cohorts Susana Santos et al. · BJOG An International Journal of Obstetrics & Gynaecology Open access 20 Feb 2019 608
25 Filopodia in cell adhesion, 3D migration and cancer cell invasion Guillaume Jacquemet, Hellyeh Hamidi, Johanna Ivaska · Current Opinion in Cell Biology ReviewOpen access 14 Jul 2015 573
26 Towards multifunctional, targeted drug delivery systems using mesoporous silica nanoparticles – opportunities & challenges Jessica M. Rosenholm, Cecilia Sahlgren, Mika Lindén · Nanoscale 2010 572
27 Ground-state-depletion fluorscence microscopy: A concept for breaking the diffraction resolution limit Stefan W. Hell, M. Kroug · Applied Physics B May 1995 545
28 Maternal body mass index, gestational weight gain, and the risk of overweight and obesity across childhood: An individual participant data meta-analysis Ellis Voerman et al. · PLoS Medicine ReviewOpen access 11 Feb 2019 543
29 Targeting of Porous Hybrid Silica Nanoparticles to Cancer Cells Jessica M. Rosenholm, Annika Meinander, Emilia Peuhu et al. · ACS Nano 23 Dec 2008 519
30 PDSM, a motif for phosphorylation-dependent SUMO modification Ville Hietakangas, Julius Anckar, Henri A. Blomster et al. · Proceedings of the National Academy of Sciences Open access 21 Dec 2005 500
31 Digital Versus Conventional Impressions in Fixed Prosthodontics: A Review Pekka Ahlholm, Kirsi Sipilä, Pekka Kalevi VALLITTU et al. · Journal of Prosthodontics Open access 2 Aug 2016 495
32 Bacterial polysaccharide synthesis and gene nomenclature Peter R. Reeves, Matthew Hobbs, Miguel A. Valvano et al. · Trends in Microbiology Review Dec 1996 495
33 Matrix metalloproteinases in wound repair (review). Laura Ravanti, Veli‐Matti Kähäri · International Journal of Molecular Medicine Oct 2000 480
34 Integrin trafficking in cells and tissues Paulina Moreno‐Layseca, Jaroslav Icha, Hellyeh Hamidi et al. · Nature Cell Biology Open access 22 Nov 2018 477
35 Vimentin function in lymphocyte adhesion and transcellular migration Mikko Nieminen, Tiina A Henttinen, Marika Merinen et al. · Nature Cell Biology 22 Jan 2006 468
36 Comparison of software packages for detecting differential expression in RNA-seq studies Fatemeh S. Seyednasrollah, Asta Laiho, Laura L. Elo · Briefings in Bioinformatics Open access 2 Dec 2013 465
37 Metabolomics and lipidomics in NAFLD: biomarkers and non-invasive diagnostic tests Mojgan Masoodi, Amalia Gastaldelli, Tuulia Hyötyläinen et al. · Nature Reviews Gastroenterology & Hepatology Review 10 Sep 2021 464
38 Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes Matej Orešič et al. · The Journal of Experimental Medicine Open access 15 Dec 2008 460
39 Vimentin coordinates fibroblast proliferation and keratinocyte differentiation in wound healing via TGF-β–Slug signaling Fang Cheng, Yue Shen, Ponnuswamy Mohanasundaram et al. · Proceedings of the National Academy of Sciences Open access 8 Jul 2016 442
40 Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars Panu K. Luukkonen et al. · Diabetes Care Open access 29 May 2018 439
41 Human breast cancer cells educate macrophages toward the M2 activation status Sofia Sousa, Régis Brion, Minnamaija Lintunen et al. · Breast Cancer Research Open access 4 Aug 2015 434
42 Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950–Metabolites in Frozen Human Plasma John A. Bowden et al. · Journal of Lipid Research Open access 7 Oct 2017 424
43 Distinctive Cancer Associations in Patients With Neurofibromatosis Type 1 Elina Uusitalo, Matti E. Rantanen, Roope A. Kallionpää et al. · Journal of Clinical Oncology 29 Feb 2016 420
44 Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease María Isabel Hernández‐Álvarez et al. · Cell Open access May 2019 411
45 Processing methods for differential analysis of LC/MS profile data Mikko Katajamaa, Matej Orešič · BMC Bioinformatics Open access 18 Jul 2005 400
46 Matrix metalloproteinases in tumor invasion Nina Johansson · Cellular and Molecular Life Sciences Open access 2000 386
47 Integrin-mediated Cell Adhesion to Type I Collagen Fibrils Johanna Jokinen, Elina Dadu, Petri Nykvist et al. · Journal of Biological Chemistry Open access Jul 2004 380
48 A systematic evaluation of normalization methods in quantitative label-free proteomics Tommi Välikangas, Tomi Suomi, Laura L. Elo · Briefings in Bioinformatics Open access 2 Oct 2016 368
49 Normalization method for metabolomics data using optimal selection of multiple internal standards Marko Sysi‐Aho, Mikko Katajamaa, Laxman Yetukuri et al. · BMC Bioinformatics Open access 15 Mar 2007 368
50 Intermediate Filament Protein Partnership in Astrocytes Camilla Eliasson, Cecilia Sahlgren, Claes‐Henric Berthold et al. · Journal of Biological Chemistry Open access Aug 1999 361

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.