Institution · UK Research and Innovation
Most cited papers from UK Research and Innovation
What are the most cited papers from UK Research and Innovation?
The most cited paper from UK Research and Innovation is "Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4" (Ulrich K. Laemmli, 1970), with 252,153 citations. Next come "DNA sequencing with chain-terminating inhibitors" (69,512) and "Detection of specific sequences among DNA fragments separated by gel electrophoresis" (32,849).
Showing 50 of 60 papers. Every paper with more than 4,522 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 Ulrich K. Laemmli · Nature | Aug 1970 | 252,153 |
| 2 | DNA sequencing with chain-terminating inhibitors Frederick Sanger, S. Nicklen, Alan R. Coulson · Proceedings of the National Academy of Sciences | Dec 1977 | 69,512 |
| 3 | Detection of specific sequences among DNA fragments separated by gel electrophoresis E.M. Southern · Journal of Molecular Biology | Nov 1975 | 32,849 |
| 4 | Phaser crystallographic software Airlie J. McCoy, Ralf W. Grosse‐Kunstleve, Paul D. Adams et al. · Journal of Applied Crystallography | 13 Jul 2007 | 21,198 |
| 5 | Continuous cultures of fused cells secreting antibody of predefined specificity Georges Köhler, César Milstein · Nature | Aug 1975 | 17,298 |
| 6 | THE GENETICS OF CAENORHABDITIS ELEGANS Sydney Brenner · Genetics | May 1974 | 15,608 |
| 7 | First principles methods using CASTEP Stewart J. Clark, Matthew Segall, Chris J. Pickard et al. · Zeitschrift für Kristallographie - Crystalline Materials | May 2005 | 14,735 |
| 8 | Observation of Gravitational Waves from a Binary Black Hole Merger B. P. Abbott et al. · Physical Review Letters | 11 Feb 2016 | 14,545 |
| 9 | A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid K. Burton · Biochemical Journal | Feb 1956 | 14,144 |
| 10 | Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid James Dewey Watson, Francis Harry Compton Crick · Nature | 25 Apr 1953 | 13,452 |
| 11 | Discussion on the paper by Spiegelhalter, Best, Carlin and van der Linde Gelfand, A. E., Trevisani, M. · ArTS Archivio della ricerca di Trieste (University of Trieste https://www.units.it/) | 2002 | 12,900 |
| 12 | Overview of the CCP 4 suite and current developments Martyn Winn, Charles C. Ballard, Kevin D. Cowtan et al. · Acta Crystallographica Section D Biological Crystallography | 17 Mar 2011 | 12,694 |
| 13 | Observation of a new particle in the search for the Standard Model Higgs boson with the ATLAS detector at the LHC G. Aad et al. · Physics Letters B | 14 Aug 2012 | 10,856 |
| 14 | Sequence and organization of the human mitochondrial genome Stephen K. Anderson, Alan T. Bankier, B. G. Barrell et al. · Nature | Apr 1981 | 9,759 |
| 15 | REFMAC 5 for the refinement of macromolecular crystal structures Garib N. Murshudov, Pavol Skubák, Andrey Andreyevich Lebedev et al. · Acta Crystallographica Section D Biological Crystallography | 17 Mar 2011 | 8,771 |
| 16 | Gaia Data Release 2 A. G. A. Brown et al. · Astronomy and Astrophysics | 24 Apr 2018 | 8,734 |
| 17 | The MR-Base platform supports systematic causal inference across the human phenome Gibran Hemani, Jie Zheng, Benjamin L. Elsworth et al. · eLife | 30 May 2018 | 8,708 |
| 18 | A Film Detection Method for Tritium‐Labelled Proteins and Nucleic Acids in Polyacrylamide Gels William M. Bonner, Ronald Alfred Laskey · European Journal of Biochemistry | Jul 1974 | 8,651 |
| 19 | α-Synuclein in Lewy bodies Maria Grazia Spillantini, Marie Luise Schmidt, Virginia M.‐Y. Lee et al. · Nature | 28 Aug 1997 | 8,529 |
| 20 | SPIRIT 2013 Statement: Defining Standard Protocol Items for Clinical Trials An‐Wen Chan, Jennifer Tetzlaff, Douglas G. Altman et al. · Annals of Internal Medicine | 5 Feb 2013 | 8,142 |
| 21 | Initial sequencing and comparative analysis of the mouse genome Asif T. Chinwalla et al. · Nature | Dec 2002 | 7,343 |
| 22 | Review of Particle Physics Masaharu Tanabashi et al. · Physical review. D/Physical review. D. | 17 Aug 2018 | 7,268 |
| 23 | The Gaia mission T. Prusti et al. · Astronomy and Astrophysics | 15 Sep 2016 | 7,118 |
| 24 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 Lorenzo Galluzzi et al. · Cell Death and Differentiation | 23 Jan 2018 | 6,760 |
| 25 | Inositol trisphosphate and calcium signalling Michael John Berridge · Nature | 1993 | 6,606 |
| 26 | Perioperative Chemotherapy versus Surgery Alone for Resectable Gastroesophageal Cancer David Cunningham, William Allum, Sally Patricia Stenning et al. · New England Journal of Medicine | 6 Jul 2006 | 6,432 |
| 27 | Application of the cross wavelet transform and wavelet coherence to geophysical time series Aslak Grinsted, John Christopher Moore, Svetlana Jevrejeva · Nonlinear processes in geophysics | 18 Nov 2004 | 6,407 |
| 28 | SCOP: A structural classification of proteins database for the investigation of sequences and structures Alexey G. Murzin, Steven E. Brenner, Tim Hubbard et al. · Journal of Molecular Biology | Apr 1995 | 6,359 |
| 29 | A new framework for developing and evaluating complex interventions: update of Medical Research Council guidance Kathryn Skivington, Lynsay Matthews, Sharon Anne Simpson et al. · BMJ | 30 Sep 2021 | 6,225 |
| 30 | RELION: Implementation of a Bayesian approach to cryo-EM structure determination Sjors H. W. Scheres · Journal of Structural Biology | 19 Sep 2012 | 6,175 |
| 31 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Daniel J. Klionsky et al. · Autophagy | 2 Jan 2016 | 6,023 |
| 32 | Review of Particle Physics J. Beringer et al. · Physical review. D. Particles, fields, gravitation, and cosmology/Physical review. D. Particles and fields | 20 Jul 2012 | 6,020 |
| 33 | The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research Nathalie Percie du Sert et al. · PLoS Biology | 14 Jul 2020 | 6,005 |
| 34 | Global physical activity levels: surveillance progress, pitfalls, and prospects Pedro Curi Hallal, Lars Bo Andersen, Fiona Bull et al. · The Lancet | Jul 2012 | 5,885 |
| 35 | The structure of the nervous system of the nematode Caenorhabditis elegans JG White, Eileen Southgate, J. Nichol Thomson et al. · Philosophical transactions of the Royal Society of London. Series B, Biological sciences | 12 Nov 1986 | 5,884 |
| 36 | Psychosocial resilience and protective mechanisms. Michael L. Rutter · American Journal of Orthopsychiatry | Jul 1987 | 5,837 |
| 37 | New tools for automated high-resolution cryo-EM structure determination in RELION-3 Jasenko Zivanov, Takanori Nakane, Björn O. Forsberg et al. · eLife | 9 Nov 2018 | 5,552 |
| 38 | WinBUGS - A Bayesian modelling framework: Concepts, structure, and extensibility David J. Lunn, Andrew C. Thomas, Nicky Best et al. · Statistics and Computing | Oct 2000 | 5,419 |
| 39 | Distantly related sequences in the alpha‐ and beta‐subunits of ATP synthase, myosin, kinases and other ATP‐requiring enzymes and a common nucleotide binding fold. John E. Walker, M Saraste, M J Runswick et al. · The EMBO Journal | Aug 1982 | 5,355 |
| 40 | Working Memory Alan Baddeley · Science | 31 Jan 1992 | 5,275 |
| 41 | How good are my data and what is the resolution? Philip Rainsford Evans, Garib N. Murshudov · Acta Crystallographica Section D Biological Crystallography | 12 Jun 2013 | 5,147 |
| 42 | Simulations of the formation, evolution and clustering of galaxies and quasars Volker Springel, Simon D. M. White, Adrian R. Jenkins et al. · Nature | Jun 2005 | 5,112 |
| 43 | Molecular characterization of a peripheral receptor for cannabinoids Sean Munro, Kerrie L. Thomas, Muna Abu-Shaar · Nature | Sep 1993 | 5,110 |
| 44 | Review of Particle Physics C. Amsler et al. · Physics Letters B | 5 Aug 2008 | 5,093 |
| 45 | The Astropy Project : Sustaining and Growing a Community-oriented Open-source Project and the Latest Major Release (v5.0) of the Core Package* The Astropy Collaboration et al. · Repository of the Academy's Library (Library of the Hungarian Academy of Sciences) | 2022 | 5,044 |
| 46 | Machine learning for molecular and materials science Keith T. Butler, Daniel W. Davies, Hugh Cartwright et al. · Nature | Jul 2018 | 5,033 |
| 47 | Genetic studies of body mass index yield new insights for obesity biology The LifeLines Cohort Study et al. · Nature | 10 Feb 2015 | 4,954 |
| 48 | Drug repurposing: progress, challenges and recommendations Sudeep P. Pushpakom, Francesco Iorio, Patrick A. Eyers et al. · Nature Reviews Drug Discovery | 12 Oct 2018 | 4,863 |
| 49 | The Atmospheric Imaging Assembly (AIA) on the Solar Dynamics Observatory (SDO) James R. Lemen et al. · Solar Physics | Jun 2011 | 4,818 |
| 50 | An atlas of genetic correlations across human diseases and traits Brendan K Bulik-Sullivan, Hilary K. Finucane, Verneri Anttila et al. · Nature Genetics | 28 Sep 2015 | 4,816 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.