| 1 |
Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
Theo Vos et al. · The Lancet
Open access637 authors |
Oct 2016 |
7,466 |
| 2 |
Contemporary Management of Acute Right Ventricular Failure: A Statement from the Heart Failure Association and the Working Group on Pulmonary Circulation and Right Ventricular Function of the European Society of Cardiology
Veli‐Pekka Harjola et al. · European Journal of Heart Failure
|
Mar 2016 |
726 |
| 3 |
Are Hospitalized or Ambulatory Patients with Heart Failure Treated in Accordance with European Society of Cardiology Guidelines? Evidence from 12 440 Patients of the ESC Heart Failure Long-Term Registry
Aldo Pietro Maggioni et al. · European Journal of Heart Failure
Open access |
26 Aug 2013 |
672 |
| 4 |
Ivosidenib and Azacitidine in IDH1 -Mutated Acute Myeloid Leukemia
Pau Montesinos, Christian Récher, Susana Pons Vives et al. · New England Journal of Medicine
Open access |
20 Apr 2022 |
512 |
| 5 |
Metal nanoparticles fabricated by green chemistry using natural extracts: biosynthesis, mechanisms, and applications
Hesham R. El‐Seedi, Rehan M. El-Shabasy, Shaden A. M. Khalifa et al. · RSC Advances
Open access |
2019 |
475 |
| 6 |
Organ Dysfunction, Injury and Failure in Acute Heart Failure: From Pathophysiology to Diagnosis and Management. A Review on Behalf of the Acute Heart Failure Committee of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC)
Veli‐Pekka Harjola et al. · European Journal of Heart Failure
Open access |
30 May 2017 |
431 |
| 7 |
Endothelial function in cardiovascular medicine: a consensus paper of the European Society of Cardiology Working Groups on Atherosclerosis and Vascular Biology, Aorta and Peripheral Vascular Diseases, Coronary Pathophysiology and Microcirculation, and Thrombosis
M. Yvonne Alexander et al. · Cardiovascular Research
Open access |
7 Apr 2020 |
398 |
| 8 |
Heart Failure in Cardiomyopathies: A Position Paper from the Heart Failure Association of the European Society of Cardiology
Petar M Seferovic et al. · European Journal of Heart Failure
Open access |
16 Apr 2019 |
389 |
| 9 |
Right Heart Dysfunction and Failure in Heart Failure with Preserved Ejection Fraction: Mechanisms and Management. Position Statement on Behalf of the Heart Failure Association of the European Society of Cardiology
Thomas M. Gorter et al. · European Journal of Heart Failure
Open access |
16 Oct 2017 |
388 |
| 10 |
The Role of Ventricular–Arterial Coupling in Cardiac Disease and Heart Failure: Assessment, Clinical Implications and Therapeutic Interventions. A Consensus Document of the European Society of Cardiology Working Group on Aorta & Peripheral Vascular Diseases, European Association of Cardiovascular Imaging, and Heart Failure Association
Ignatios Ikonomidis et al. · European Journal of Heart Failure
Open access |
12 Mar 2019 |
382 |
| 11 |
Indications for haematopoietic cell transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2022
John Andrew Snowden, Isabel Sánchez‐Ortega, Selim Corbacioglu et al. · Bone Marrow Transplantation
Open access |
19 May 2022 |
381 |
| 12 |
PD-1 Blockade in Anaplastic Thyroid Carcinoma
Jaume Capdevila et al. · Journal of Clinical Oncology
Open access |
4 May 2020 |
364 |
| 13 |
Consensus guidelines for lumbar puncture in patients with neurological diseases
Sebastiaan Engelborghs et al. · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring
Open access |
2017 |
361 |
| 14 |
European Stroke Organisation guideline on endarterectomy and stenting for carotid artery stenosis
Leo Hermann Bonati, Stavros K. Kakkos, Joachim Berkefeld et al. · European Stroke Journal
Open access |
11 May 2021 |
350 |
| 15 |
EACVI/EHRA Expert Consensus Document on the role of multi-modality imaging for the evaluation of patients with atrial fibrillation
Erwan Donal et al. · European Heart Journal - Cardiovascular Imaging
Open access |
9 Feb 2016 |
343 |
| 16 |
New International Guidelines and Consensus on the Use of Lung Ultrasound
Libertario Demi et al. · Journal of Ultrasound in Medicine
Open access |
22 Aug 2022 |
341 |
| 17 |
Effect of remote ischaemic conditioning on clinical outcomes in patients with acute myocardial infarction (CONDI-2/ERIC-PPCI): a single-blind randomised controlled trial
Derek John Hausenloy et al. · The Lancet
Open access587 authors |
6 Sep 2019 |
339 |
| 18 |
Apoptosis in myocardial ischaemia and infarction
Paul A.J. Krijnen, R Nijmeijer, C J L M Meijer et al. · Journal of Clinical Pathology
Open access |
25 Oct 2002 |
333 |
| 19 |
Methods of cryopreservation of testicular tissue with viable spermatogonia in pre-pubertal boys undergoing gonadotoxic cancer treatment
Victoria Keros, Kjell R. Hultenby, Birgit Borgström et al. · Human Reproduction
|
26 Jan 2007 |
332 |
| 20 |
Effects of sex steroids on components of the insulin resistance syndrome in transsexual subjects
Jolanda M. H. Elbers, Erik J. Giltay, Tom Teerlink et al. · Clinical Endocrinology
Open access |
17 Apr 2003 |
319 |
| 21 |
Aortic Valve Replacement Versus Conservative Treatment in Asymptomatic Severe Aortic Stenosis: The AVATAR Trial
Marko Banovic et al. · Circulation
Open access |
13 Nov 2021 |
300 |
| 22 |
The Heart Failure Association Atlas: Heart Failure Epidemiology and Management Statistics 2019
Petar M Seferovic et al. · European Journal of Heart Failure
Open access |
26 Feb 2021 |
289 |
| 23 |
Rates and predictors of hypoglycaemia in 27 585 people from 24 countries with insulin‐treated type 1 and type 2 diabetes: the global HAT study
Kamlesh K. Khunti, Saud N. Alsifri, Ronnie Aronson et al. · Diabetes Obesity and Metabolism
Open access |
10 May 2016 |
280 |
| 24 |
Towards new understanding of the heart structure and function
Francisco Torrent-Guasp, Mladen J. Kočica, Antonio Francesco Corno et al. · European Journal of Cardio-Thoracic Surgery
Open access |
29 Dec 2004 |
276 |
| 25 |
The dementia of dementia praecox
E.C. Johnstone, Timothy John Crow, Chris Frith et al. · Acta Psychiatrica Scandinavica
|
Apr 1978 |
272 |
| 26 |
Enhancing functional abilities and cognitive integration of the lower limb prosthesis
Francesco Maria Petrini, Giacomo Valle, Marko Bumbaširević et al. · Science Translational Medicine
Open access |
2 Oct 2019 |
271 |
| 27 |
Artificial intelligence in systematic reviews: promising when appropriately used
Sanne H B van Dijk, Marjolein G J Brusse-Keizer, Charlotte Cecile Bucsán et al. · BMJ Open
ReviewOpen access |
Jul 2023 |
251 |
| 28 |
Effects of Tadalafil Treatment on Erectile Function Recovery Following Bilateral Nerve-sparing Radical Prostatectomy: A Randomised Placebo-controlled Study (REACTT)
Francesco Montorsi, Gerald B Brock, Jens-Uwe Stolzenburg et al. · European Urology
|
12 Oct 2013 |
251 |
| 29 |
Impact of Alarm Fatigue on the Work of Nurses in an Intensive Care Environment—A Systematic Review
Katarzyna Lewandowska, Magdalena Weisbrot, Aleksandra Cieloszyk et al. · International Journal of Environmental Research and Public Health
ReviewOpen access |
13 Nov 2020 |
250 |
| 30 |
Overview of the current status of familial hypercholesterolaemia care in over 60 countries - The EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)
Antonio J. Vallejo‐Vaz et al. · Atherosclerosis
Open access |
28 Sep 2018 |
242 |
| 31 |
Outcomes of allogeneic haematopoietic stem cell transplantation from HLA-matched and alternative donors: a European Society for Blood and Marrow Transplantation registry retrospective analysis
Roni Shouval, Joshua Alexander Fein, Myriam Labopin et al. · The Lancet Haematology
Open access |
30 Aug 2019 |
228 |
| 32 |
Perivascular adipose tissue as a source of therapeutic targets and clinical biomarkers
Charalambos A. Antoniades, Dimitris Tousoulis, Marija Vavlukis et al. · European Heart Journal
Open access |
19 Jul 2023 |
225 |
| 33 |
Rivastigmine: the advantages of dual inhibition of acetylcholinesterase and butyrylcholinesterase and its role in subcortical vascular dementia and Parkinson’s disease dementia
Nagaendran Kandiah, Ming-Chyi Pai, Vorapun Senanarong et al. · Clinical Interventions in Aging
Open access |
Apr 2017 |
223 |
| 34 |
Hypertension and cardiac arrhythmias: a consensus document from the European Heart Rhythm Association (EHRA) and ESC Council on Hypertension, endorsed by the Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS) and Sociedad Latinoamericana de Estimulación Cardíaca y Electrofisiología (SOLEACE)
Gregory Y. H. Lip et al. · EP Europace
Open access |
Jun 2017 |
222 |
| 35 |
Phase II studies of nebulised Arikace in CF patients withPseudomonas aeruginosainfection
John Paul Clancy, Lieven Dupont, Michael W. Konstan et al. · Thorax
Open access |
8 Jun 2013 |
222 |
| 36 |
The Role of 3D Printing in Planning Complex Medical Procedures and Training of Medical Professionals—Cross-Sectional Multispecialty Review
Jarosław Meyer-Szary, Marlon Souza Luis, Szymon Mikulski et al. · International Journal of Environmental Research and Public Health
Open access |
11 Mar 2022 |
217 |
| 37 |
Trastuzumab deruxtecan in HER2-positive advanced breast cancer with or without brain metastases: a phase 3b/4 trial
Nadia Harbeck et al. · Nature Medicine
Open access |
13 Sep 2024 |
216 |
| 38 |
Age-dependent and sex-dependent disparity in mortality in patients with adrenal incidentalomas and autonomous cortisol secretion: an international, retrospective, cohort study
Timo Deutschbein et al. · The Lancet Diabetes & Endocrinology
Open access |
6 May 2022 |
197 |
| 39 |
GH-releasing hormone and GH-releasing peptide-6 for diagnostic testing in GH-deficient adults
Vera M. POPOVIC, Alfonso Leal, Dragan Micić et al. · The Lancet
|
Sep 2000 |
188 |
| 40 |
Efficacy of dietary hempseed oil in patients with atopic dermatitis
J. C. Callaway, Ursula Schwab, Ilkka T. Harvima et al. · Journal of Dermatological Treatment
|
Apr 2005 |
186 |
| 41 |
European Society of Cardiology/Heart Failure Association Position Paper on the Role and Safety of New Glucose-Lowering Drugs in Patients with Heart Failure
Petar M Seferovic et al. · European Journal of Heart Failure
Open access |
9 Dec 2019 |
183 |
| 42 |
Early diagnosis and better rhythm management to improve outcomes in patients with atrial fibrillation: the 8th AFNET/EHRA consensus conference
Renate B. Schnabel et al. · EP Europace
Open access |
14 Apr 2022 |
180 |
| 43 |
ESCMID COVID-19 living guidelines: drug treatment and clinical management
Michele Bartoletti, Özlem Kurt Azap, Aleksandra M. Barac et al. · Clinical Microbiology and Infection
Open access |
22 Nov 2021 |
180 |
| 44 |
In-Hospital and 1-Year Mortality Associated with Diabetes in Patients with Acute Heart Failure: Results from the ESC-HFA Heart Failure Long-Term Registry
Giovanni Targher, Marco Dauriz, Cécile Laroche et al. · European Journal of Heart Failure
Open access |
28 Oct 2016 |
172 |
| 45 |
Variation in GP decisions on antihypertensive treatment in oldest-old and frail individuals across 29 countries
Sven Streit et al. · BMC Geriatrics
Open access |
20 Apr 2017 |
171 |
| 46 |
2-Fluorine-18-fluoro-2-deoxy-D glucose positron emission tomography in the pretreatment staging of Hodgkin's disease: Influence on patient management in a single institution
Savannah C. Partridge, A. Timothy, Michael J. O'Doherty et al. · Annals of Oncology
Open access |
Oct 2000 |
171 |
| 47 |
Use of Chest Imaging in the Diagnosis and Management of COVID-19: A WHO Rapid Advice Guide
Elie A. Akl et al. · Radiology
Open access |
30 Jul 2020 |
170 |
| 48 |
A 12-Year Follow-up Study of Patients With Newly Diagnosed Lone Atrial Fibrillation
Tatjana Potpara, Goran R. Stankovic, Branko Beleslin et al. · CHEST Journal
|
26 May 2011 |
168 |
| 49 |
Geographic and age variations in mutational processes in colorectal cancer
Marcos Díaz‐Gay et al. · Nature
Open access |
23 Apr 2025 |
162 |
| 50 |
Mucormycosis in patients with COVID‐19: A cross‐sectional descriptive multicentre study from Iran
Farzad Pakdel, Kazem Ahmadikia, Mohammadreza Salehi et al. · Mycoses
Open access |
7 Jun 2021 |
160 |