Institution · Wellcome Trust
Most cited papers from Wellcome Trust
Wellcome Trust
What are the most cited papers from Wellcome Trust?
The most cited paper from Wellcome Trust is "PHENIX : a comprehensive Python-based system for macromolecular structure solution" (Paul D. Adams, Pavel V. Afonine, G. Bunkóczi et al., 2010), with 24,924 citations. Next come "Initial sequencing and analysis of the human genome" (24,745) and "Phaser crystallographic software" (21,198).
Showing 50 of 59 papers. Every paper with more than 2,938 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | PHENIX : a comprehensive Python-based system for macromolecular structure solution Paul D. Adams, Pavel V. Afonine, G. Bunkóczi et al. · Acta Crystallographica Section D Biological Crystallography | 21 Jan 2010 | 24,924 |
| 2 | Initial sequencing and analysis of the human genome Eric S. Lander et al. · Nature | Feb 2001 | 24,745 |
| 3 | Phaser crystallographic software Airlie J. McCoy, Ralf W. Grosse‐Kunstleve, Paul D. Adams et al. · Journal of Applied Crystallography | 13 Jul 2007 | 21,198 |
| 4 | A global reference for human genetic variation Corresponding authors et al. · Nature | 29 Sep 2015 | 20,444 |
| 5 | Fast, scalable generation of high‐quality protein multiple sequence alignments using Clustal Omega Fabian Sievers, Andreas Wilm, David Dineen et al. · Molecular Systems Biology | 11 Oct 2011 | 16,563 |
| 6 | Nitric oxide: physiology, pathophysiology, and pharmacology. Salvador Moncada, Richard M. J. Palmer, E.A. Higgs · Pharmacological Reviews | Jun 1991 | 15,612 |
| 7 | Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor Richard M. J. Palmer, Anthony G. Ferrige, Salvador Moncada · Nature | Jun 1987 | 10,799 |
| 8 | EMBOSS: The European Molecular Biology Open Software Suite Peter Rice, Ian Longden, Alan J. Bleasby · Trends in Genetics | Jun 2000 | 10,011 |
| 9 | Velvet: Algorithms for de novo short read assembly using de Bruijn graphs Daniel R. Zerbino, Ewan Birney · Genome Research | 18 Mar 2008 | 9,816 |
| 10 | Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls Paul R. Burton et al. · Nature | 6 Jun 2007 | 9,692 |
| 11 | An integrated map of genetic variation from 1,092 human genomes Gil A. McVean et al. · Nature | 31 Oct 2012 | 8,281 |
| 12 | A map of human genome variation from population-scale sequencing Richard M. Durbin et al. · Nature | 26 Oct 2010 | 8,156 |
| 13 | UniProt: the Universal Protein knowledgebase Rolf Apweiler · Nucleic Acids Research | 17 Dec 2003 | 7,889 |
| 14 | The PRIDE database and related tools and resources in 2019: improving support for quantification data Yasset Pérez‐Riverol et al. · Nucleic Acids Research | 22 Oct 2018 | 7,481 |
| 15 | The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences Yasset Pérez‐Riverol, Jingwen Bai, Chakradhar Bandla et al. · Nucleic Acids Research | 15 Oct 2021 | 6,874 |
| 16 | The L-Arginine-Nitric Oxide Pathway Franklin H. Epstein, Salvador Moncada, Annie Higgs · New England Journal of Medicine | 30 Dec 1993 | 6,737 |
| 17 | LigPlot+: Multiple Ligand–Protein Interaction Diagrams for Drug Discovery Roman A. Laskowski, Mark Basil Swindells · Journal of Chemical Information and Modeling | 5 Oct 2011 | 6,702 |
| 18 | The Pfam protein families database: towards a more sustainable future ROBERT FINN, Penelope C. Coggill, Ruth Y. Eberhardt et al. · Nucleic Acids Research | 15 Dec 2015 | 6,569 |
| 19 | Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 Theo Vos et al. · The Lancet | 7 Jun 2015 | 6,558 |
| 20 | Nonparametric permutation tests for functional neuroimaging: A primer with examples Thomas E. Nichols, Andrew P. Holmes · Human Brain Mapping | 15 Oct 2001 | 6,548 |
| 21 | The International HapMap Project Richard A. Gibbs et al. · Nature | 18 Dec 2003 | 6,187 |
| 22 | The Reactome pathway Knowledgebase Antonio Fabregat et al. · Nucleic Acids Research | 9 Dec 2015 | 6,015 |
| 23 | EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update Josef S Smolen et al. · Annals of the Rheumatic Diseases | 6 Mar 2017 | 5,808 |
| 24 | The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression Thomas Derrien et al. · Genome Research | Sep 2012 | 5,308 |
| 25 | The zebrafish reference genome sequence and its relationship to the human genome Kerstin Howe et al. · Nature | 16 Apr 2013 | 5,261 |
| 26 | The Pfam protein families database in 2019 Sara El-Gebali, Jaina Mistry, Alex Bateman et al. · Nucleic Acids Research | 9 Oct 2018 | 5,256 |
| 27 | Assessment of eating disorders: Interview or self‐report questionnaire? Christopher G. Fairburn, Sarah J. Beglin · International Journal of Eating Disorders | Dec 1994 | 5,143 |
| 28 | Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK Merryn Voysey et al. · The Lancet | 8 Dec 2020 | 5,030 |
| 29 | PRODRG: a tool for high-throughput crystallography of protein–ligand complexes Alexander W. Schüttelkopf, Daan M. F. van Aalten · Acta Crystallographica Section D Biological Crystallography | 21 Jul 2004 | 4,854 |
| 30 | Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics Claudia Giambartolomei, Damjan Vukcevic, Eric E. Schadt et al. · PLoS Genetics | 15 May 2014 | 4,798 |
| 31 | Vascular endothelial cells synthesize nitric oxide from L-arginine Richard M. J. Palmer, D. Ashton, Salvador Moncada · Nature | Jun 1988 | 4,797 |
| 32 | Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt Steffen Durinck, Paul T. Spellman, Ewan Birney et al. · Nature Protocols | 22 Jul 2009 | 4,773 |
| 33 | The EMBL-EBI search and sequence analysis tools APIs in 2019 Fábio Madeira, Young Mi Park, Joon Lee et al. · Nucleic Acids Research | 3 Apr 2019 | 4,708 |
| 34 | A second generation human haplotype map of over 3.1 million SNPs Sarah Shaw Murray et al. · Nature | Oct 2007 | 4,615 |
| 35 | Genome sequence of the human malaria parasite Plasmodium falciparum Malcolm J. Gardner et al. · Nature | Oct 2002 | 4,520 |
| 36 | PHENIX : building new software for automated crystallographic structure determination Paul D. Adams, Ralf W. Grosse‐Kunstleve, Li‐Wei Hung et al. · Acta Crystallographica Section D Biological Crystallography | 21 Oct 2002 | 4,437 |
| 37 | mRNA-Seq whole-transcriptome analysis of a single cell Fuchou Tang, Cátálin Bárbácioru, Yangzhou Wang et al. · Nature Methods | 6 Apr 2009 | 4,191 |
| 38 | Minimum information about a microarray experiment (MIAME)—toward standards for microarray data Alvis Brāzma et al. · Nature Genetics | Dec 2001 | 4,140 |
| 39 | Real-space refinement in PHENIX for cryo-EM and crystallography Pavel V. Afonine, Billy K. Poon, Randy J. Read et al. · Acta Crystallographica Section D Structural Biology | 30 May 2018 | 3,869 |
| 40 | The repertoire of mutational signatures in human cancer Ludmil B. Alexandrov et al. · Nature | 5 Feb 2020 | 3,854 |
| 41 | How to correct susceptibility distortions in spin-echo echo-planar images: application to diffusion tensor imaging Jesper Andersson, Stefan T. Skare, John Ashburner · NeuroImage | 22 Sep 2003 | 3,841 |
| 42 | Systematic functional analysis of the Caenorhabditis elegans genome using RNAi Ravi S. Kamath, Andrew G. Fraser, Dong Yan et al. · Nature | 2003 | 3,792 |
| 43 | The Lancet Commission on global mental health and sustainable development Vikram Patel et al. · The Lancet | Oct 2018 | 3,714 |
| 44 | 2016 update of the PRIDE database and its related tools Juan Antonio Vizcaíno, Attila Csordás, Noemí del‐Toro et al. · Nucleic Acids Research | 2 Nov 2015 | 3,695 |
| 45 | An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation Salvador Moncada, Ryszard Jerzy Gryglewski, S Bunting et al. · Nature | Oct 1976 | 3,608 |
| 46 | TRIPOD+AI statement: updated guidance for reporting clinical prediction models that use regression or machine learning methods Professor Gary S. Collins et al. · BMJ | 16 Apr 2024 | 3,581 |
| 47 | Pan-cancer analysis of whole genomes Lauri A. Aaltonen et al. · Nature | 5 Feb 2020 | 3,360 |
| 48 | The SWISS-PROT protein sequence data bank and its supplement TrEMBL in 1999 Amos Bairoch, Rolf Apweiler · Nucleic Acids Research | 1999 | 3,239 |
| 49 | Automated generation of heuristics for biological sequence comparison Guy Slater, Ewan Birney · BMC Bioinformatics | 15 Feb 2005 | 3,236 |
| 50 | ACPYPE - AnteChamber PYthon Parser interfacE Alan Sousa da Silva, Wim Vranken · BMC Research Notes | 23 Jul 2012 | 3,233 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.