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Most cited papers from Yale University

What are the most cited papers from Yale University?

The most cited paper from Yale University is "Meta-analysis in clinical trials" (Rebecca DerSimonian, Nan M. Laird, 1986), with 40,073 citations. Next come "A global reference for human genetic variation" (20,444) and "An integrated encyclopedia of DNA elements in the human genome" (19,751).

Showing 50 of 60 papers. Every paper with more than 6,558 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Meta-analysis in clinical trials Rebecca DerSimonian, Nan M. Laird · Controlled Clinical Trials Sep 1986 40,073
2 A global reference for human genetic variation Corresponding authors et al. · Nature Open access815 authors 29 Sep 2015 20,444
3 An integrated encyclopedia of DNA elements in the human genome Ian Dunham et al. · Nature Open access442 authors Sep 2012 19,751
4 Testing for a unit root in time series regression Peter C.B. Phillips, Pierre Perrón · Biometrika 1988 18,270
5 Measurements of Ω and Λ from 42 High‐Redshift Supernovae S. Perlmutter et al. · The Astrophysical Journal Open access Jun 1999 18,225
6 Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement Massimo Dominici, Katarina Le Blanc, Ingo Mueller et al. · Cytotherapy 2006 18,014
7 Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination Axel T. Brünger, Paul D. Adams, G. Marius Clore et al. · Acta Crystallographica Section D Biological Crystallography Sep 1998 15,809
8 Development and Testing of the OPLS All-Atom Force Field on Conformational Energetics and Properties of Organic Liquids William L. Jorgensen, David S. Maxwell, Julian Tirado‐Rives · Journal of the American Chemical Society 13 Nov 1996 15,659
9 Algorithm AS 136: A K-Means Clustering Algorithm John A. Hartigan, M. Anthony Wong · Journal of the Royal Statistical Society Series C (Applied Statistics) 1979 14,594
10 Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010 Rafael Lozano et al. · The Lancet Open access191 authors Dec 2012 14,344
11 The Sequence of the Human Genome J. Craig Venter et al. · Science 273 authors 16 Feb 2001 13,717
12 RNA-Seq: a revolutionary tool for transcriptomics Zhong Wang, Mark Gerstein, Michael Snyder · Nature Reviews Genetics ReviewOpen access 18 Nov 2008 13,619
13 Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology Dec 1973 12,981
14 Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer Suzanne Louise Topalian et al. · New England Journal of Medicine Open access 14 Jun 2012 12,842
15 Testing the null hypothesis of stationarity against the alternative of a unit root Denis Kwiatkowski, Peter C.B. Phillips, Peter Schmidt et al. · Journal of Econometrics Oct 1992 12,778
16 Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes Bernard Zinman, Christoph Wanner, John M. Lachin et al. · New England Journal of Medicine Open access 17 Sep 2015 12,282
17 A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 Stephen S Lim et al. · The Lancet Open access209 authors Dec 2012 12,027
18 Eigenfaces vs. Fisherfaces: recognition using class specific linear projection Peter N. Belhumeur, João P. Hespanha, David Kriegman · IEEE Transactions on Pattern Analysis and Machine Intelligence Jul 1997 11,777
19 Observation of a new particle in the search for the Standard Model Higgs boson with the ATLAS detector at the LHC G. Aad et al. · Physics Letters B Open access2,932 authors 14 Aug 2012 10,856
20 Trends, Rhythms, and Aberrations in Global Climate 65 Ma to Present James C. Zachos, Mark Pagani, Lisa C. Sloan et al. · Science 27 Apr 2001 10,656
21 The Sloan Digital Sky Survey: Technical Summary Donald G. York et al. · The Astronomical Journal Open access144 authors Sep 2000 10,547
22 The mutational constraint spectrum quantified from variation in 141,456 humans Konrad J. Karczewski et al. · Nature Open access177 authors 27 May 2020 10,422
23 The integrative review: updated methodology Robin Whittemore, Kathleen Astin Knafl · Journal of Advanced Nursing 2 Nov 2005 10,110
24 A Short Physical Performance Battery Assessing Lower Extremity Function: Association With Self-Reported Disability and Prediction of Mortality and Nursing Home Admission Jack M. Guralnik, E. M. Simonsick, Luigi Ferrucci et al. · Journal of Gerontology Mar 1994 9,940
25 Bank Runs, Deposit Insurance, and Liquidity Douglas W. Diamond, Philip H. Dybvig · Journal of Political Economy Open access Jun 1983 9,677
26 A simulation study of the number of events per variable in logistic regression analysis Peter N. Peduzzi, John Concato, Elizabeth Kemper et al. · Journal of Clinical Epidemiology Open access Dec 1996 9,562
27 Nivolumab versus Docetaxel in Advanced Nonsquamous Non–Small-Cell Lung Cancer H. Borghaei et al. · New England Journal of Medicine Open access 27 Sep 2015 9,557
28 Emotional Intelligence Peter Salovey, John D. Mayer · Imagination Cognition and Personality Mar 1990 9,321
29 A Closed-Form Solution for Options with Stochastic Volatility with Applications to Bond and Currency Options Steven L. Heston · Review of Financial Studies Apr 1993 9,255
30 Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 Christopher J L Murray et al. · The Lancet Open access362 authors Dec 2012 9,055
31 Motivation through the design of work: test of a theory J. Richard Hackman, Greg R. Oldham · Organizational Behavior and Human Performance Aug 1976 8,932
32 Inference and analysis of cell-cell communication using CellChat Suoqin Jin, Christian Fernando Guerrero‐Juarez, Lihua Zhang et al. · Nature Communications Open access 17 Feb 2021 8,891
33 Finding the missing heritability of complex diseases Teri A. Manolio et al. · Nature Open access Oct 2009 8,637
34 Science and technology for water purification in the coming decades Mark A. Shannon, Paul W. Bohn, Menachem Elimelech et al. · Nature 19 Mar 2008 8,492
35 Coordination of groups of mobile autonomous agents using nearest neighbor rules Ali Jadbabaie, Jie Lin, A. Stephen Morse · IEEE Transactions on Automatic Control Open access Jun 2003 8,471
36 Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 Theo Vos et al. · The Lancet Open access358 authors Dec 2012 8,461
37 Innate Immune Recognition Charles A. Janeway, Ruslan M. Medzhitov · Annual Review of Immunology Review Apr 2002 8,439
38 An integrated map of genetic variation from 1,092 human genomes Gil A. McVean et al. · Nature Open access363 authors 31 Oct 2012 8,281
39 Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma James Larkin et al. · New England Journal of Medicine Open access 31 May 2015 8,266
40 A map of human genome variation from population-scale sequencing Richard M. Durbin et al. · Nature Open access337 authors 26 Oct 2010 8,156
41 Identification and control of dynamical systems using neural networks Kumpati S. Narendra, Kavya Parthasarathy · IEEE Transactions on Neural Networks Mar 1990 8,035
42 The Fusiform Face Area: A Module in Human Extrastriate Cortex Specialized for Face Perception Nancy Kanwisher, Josh H. McDermott, Marvin M. Chun · Journal of Neuroscience Open access Jun 1997 8,016
43 Cell Signaling by Receptor Tyrosine Kinases Mark A. Lemmon, Joseph Schlessinger · Cell Open access Jun 2010 8,012
44 Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease Brent R. Stockwell et al. · Cell Open access Oct 2017 7,867
45 Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015 Mohammad Hossein Forouzanfar et al. · The Lancet Open access654 authors Oct 2016 7,829
46 The Yale-Brown Obsessive Compulsive Scale Wayne K. Goodman · Archives of General Psychiatry Nov 1989 7,707
47 Electrospray Ionization for Mass Spectrometry of Large Biomolecules John B. Fenn, Matthias Mann, Chin Kai Meng et al. · Science 6 Oct 1989 7,638
48 Early Palliative Care for Patients with Metastatic Non–Small-Cell Lung Cancer Jennifer S. Temel, Joseph Andrew Greer, Alona Muzikansky et al. · New England Journal of Medicine 18 Aug 2010 7,560
49 Structural absorption by barbule microstructures of super black bird of paradise feathers Dakota E. McCoy, Teresa J. Feo, Todd Alan Harvey et al. · Nature Communications Open access 27 Dec 2017 7,502
50 Glucose clamp technique: a method for quantifying insulin secretion and resistance. R. A. DeFronzo, J. D. Tobin, R Andres · American Journal of Physiology-Endocrinology and Metabolism Sep 1979 7,488

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.