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Most cited papers in Biomaterials

What are the most cited papers in Biomaterials?

The most cited paper in Biomaterials is "Controlled growth of monodisperse silica spheres in the micron size range" (Werner Stöber, Arthur G. Fink, Ernst Bohn, 1968), with 14,524 citations. Next come "Tissue Engineering" (9,666) and "Nanocarriers as an emerging platform for cancer therapy" (8,681).

Showing 50 of 100 papers. Every paper with more than 3,352 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Controlled growth of monodisperse silica spheres in the micron size range Werner Stöber, Arthur G. Fink, Ernst Bohn · Journal of Colloid and Interface Science 1968 14,524
2 Tissue Engineering Róbert Langer, Joseph P. Vacanti · Science 14 May 1993 9,666
3 Nanocarriers as an emerging platform for cancer therapy Dan Peer, Jeffrey M. Karp, Seungpyo Hong et al. · Nature Nanotechnology Dec 2007 8,681
4 An Empirical Method for Estimating the Degree of Crystallinity of Native Cellulose Using the X-Ray Diffractometer Leon D. Segal, Joseph J. Creely, Andrew Martin et al. · Textile Research Journal Oct 1959 8,675
5 Chitin and chitosan: Properties and applications Marguerite Rinaudo · Progress in Polymer Science Jul 2006 8,231
6 Alginate: Properties and biomedical applications Kuen Yong Lee, David J. Mooney · Progress in Polymer Science Open access 7 Jul 2011 8,099
7 Engineering precision nanoparticles for drug delivery Michael J. Mitchell, Margaret M. Billingsley, Rebecca M. Haley et al. · Nature Reviews Drug Discovery ReviewOpen access 4 Dec 2020 7,854
8 A review on polymer nanofibers by electrospinning and their applications in nanocomposites Zheng‐Ming Huang, Yanzhong Zhang, M. Kotaki et al. · Composites Science and Technology 7 Jul 2003 7,551
9 Cellulose: Fascinating Biopolymer and Sustainable Raw Material Dieter Klemm, Brigitte Heublein, Hans‐Peter Fink et al. · Angewandte Chemie International Edition 28 Apr 2005 7,510
10 Self-Assembly at All Scales George M. Whitesides, Bartosz A. Grzybowski · Science 29 Mar 2002 7,462
11 Molecular Mechanisms of Stress-Responsive Changes in Collagen and Elastin Networks in Skin Jazli Aziz, Hafiz Shezali, Zamri Radzi et al. · Skin Pharmacology and Physiology 2016 7,308
12 Understanding biophysicochemical interactions at the nano–bio interface André E. Nel, Lutz Mädler, Darrell Velegol et al. · Nature Materials 14 Jun 2009 7,073
13 Principles of nanoparticle design for overcoming biological barriers to drug delivery Elvin Blanco, Haifa Shen, Mauro Ferrari · Nature Biotechnology Open access Sep 2015 6,967
14 Polymer/layered silicate nanocomposites: a review from preparation to processing Suprakas Sinha Ray, Masami Okamoto · Progress in Polymer Science 17 Oct 2003 6,798
15 Magnetic Iron Oxide Nanoparticles: Synthesis, Stabilization, Vectorization, Physicochemical Characterizations, and Biological Applications Sophie Laurent, Delphine Forge, Marc Port et al. · Chemical Reviews Review Jun 2008 6,788
16 Magnetic Nanoparticles: Synthesis, Protection, Functionalization, and Application An‐Hui Lu, Elena Lorena Salabaş, Ferdi Schüth · Angewandte Chemie International Edition 5 Feb 2007 6,770
17 Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications Ajay Kumar Gupta, Mona Sethi Gupta · Biomaterials 11 Dec 2004 6,765
18 A Chemical Classification of Volcanic Rocks Based on the Total Alkali-Silica Diagram M. J. Le Bas, R. W. Le Maitre, Albert Streckeisen et al. · Journal of Petrology Jun 1986 6,747
19 Cellulose nanomaterials review: structure, properties and nanocomposites Robert J. Moon, Ashlie Martini, John A. Nairn et al. · Chemical Society Reviews Review 2011 6,746
20 Nano based drug delivery systems: recent developments and future prospects Jayanta Kumar Patra, Gitishree Das, Leonardo Fernandes Fraceto et al. · Journal of Nanobiotechnology Open access 19 Sep 2018 6,726
21 Aggregation-induced emission Yuning Hong, Jacky W. Y. Lam, Ben Zhong Tang · Chemical Society Reviews ReviewOpen access 2011 6,364
22 Organic matter and water‐stable aggregates in soils Judith M. Tisdall, JM Oades · Journal of Soil Science Jun 1982 6,297
23 Stimuli-responsive nanocarriers for drug delivery Simona Mura, Julien Nicolas, Patrick Couvreur · Nature Materials 23 Oct 2013 6,259
24 A review of chitin and chitosan applications Majeti N. V. Ravi Kumar · Reactive and Functional Polymers Nov 2000 6,029
25 Cellulose Nanocrystals: Chemistry, Self-Assembly, and Applications Youssef Habibi, Lucian A. Lucia, Orlando José Rojas · Chemical Reviews Review 4 Mar 2010 5,952
26 Applications of magnetic nanoparticles in biomedicine Quentin A. Pankhurst, Joan Connolly, Stephen K Jones et al. · Journal of Physics D Applied Physics 19 Jun 2003 5,871
27 Cancer nanomedicine: progress, challenges and opportunities Jinjun Shi, Philip W. Kantoff, Richard F. Wooster et al. · Nature reviews. Cancer ReviewOpen access 11 Nov 2016 5,834
28 Hydrogel: Preparation, characterization, and applications: A review Enas M. Ahmed · Journal of Advanced Research Open access 18 Jul 2013 5,774
29 Mehlich 3 soil test extractant: A modification of Mehlich 2 extractant Adolf Mehlich · Communications in Soil Science and Plant Analysis Dec 1984 5,643
30 Electrospinning of Nanofibers: Reinventing the Wheel? Dan Li, Yier Xia · Advanced Materials 19 Jul 2004 5,514
31 Hydrogels for Tissue Engineering Kuen Yong Lee, David J. Mooney · Chemical Reviews Review 31 May 2001 5,279
32 Hydrogels for tissue engineering: scaffold design variables and applications Jeanie L. Drury, David J. Mooney · Biomaterials 30 Jun 2003 5,130
33 Analysis of nanoparticle delivery to tumours Stefan Wilhelm, Anthony J. Tavares, Qin Dai et al. · Nature Reviews Materials ReviewOpen access 26 Apr 2016 5,120
34 Foreign body reaction to biomaterials James Melvin Anderson, Analiz Rodriguez, David T. Chang · Seminars in Immunology Open access 7 Jan 2008 5,112
35 Electrospinning: A fascinating fiber fabrication technique Nandana Bhardwaj, Subhas Chandra Kundu · Biotechnology Advances 26 Jan 2010 5,041
36 Electrospinning and Electrospun Nanofibers: Methods, Materials, and Applications Jiajia Xue, Tong S. Wu, Yunqian Dai et al. · Chemical Reviews ReviewOpen access 27 Mar 2019 5,019
37 Wound Healing--Aiming for Perfect Skin Regeneration Paul B. Martin · Science 4 Apr 1997 4,845
38 Liposomal drug delivery systems: From concept to clinical applications Theresa M. Allen, Pieter R. Cullis · Advanced Drug Delivery Reviews Review Oct 2012 4,816
39 Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier Hirenkumar K. Makadia, Steven J. Siegel · Polymers Open access 26 Aug 2011 4,766
40 Bioinspired structural materials Ulrike G. K. Wegst, Hao Yu Bai, Eduardo Saiz et al. · Nature Materials 26 Oct 2014 4,755
41 Microbial Cellulose Utilization: Fundamentals and Biotechnology Lee Rybeck Lynd, Paul J. Weimer, Willem Heber van Zyl et al. · Microbiology and Molecular Biology Reviews ReviewOpen access Sep 2002 4,736
42 Review on Zinc Oxide Nanoparticles: Antibacterial Activity and Toxicity Mechanism Amna Hassan Sirelkhatim, Shahrom Mahmud, Azman Seeni et al. · Nano-Micro Letters Open access 18 Apr 2015 4,606
43 DLS and zeta potential – What they are and what they are not? Sourav Bhattacharjee · Journal of Controlled Release 12 Jun 2016 4,597
44 Stabilization mechanisms of soil organic matter: Implications for C-saturation of soils Johan Six, Richard T. Conant, E. A. Paul et al. · Plant and Soil Apr 2002 4,578
45 Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering Matthias P. Lütolf, Jeffrey A. Hubbell · Nature Biotechnology Open access 2005 4,561
46 Magnesium Barry Leslie Mordike, T.R. Ebert · Materials Science and Engineering A Apr 2001 4,545
47 Drug Delivery Systems: Entering the Mainstream Theresa M. Allen, Pieter R. Cullis · Science 19 Mar 2004 4,545
48 PEGylation as a strategy for improving nanoparticle-based drug and gene delivery Jung Soo Suk, Qingguo Xu, Nam‐Ho Kim et al. · Advanced Drug Delivery Reviews ReviewOpen access 19 Oct 2015 4,511
49 Magnesium and its alloys as orthopedic biomaterials: A review Mark P. Staiger, Alexis Mari Pietak, Jerawala Huadmai et al. · Biomaterials 25 Oct 2005 4,473
50 Nanocelluloses: A New Family of Nature‐Based Materials Dieter Klemm, Friederike Krämer, Sebastian Moritz et al. · Angewandte Chemie International Edition 20 May 2011 4,473

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.