Most cited papers in Biomedical Engineering
What are the most cited papers in Biomedical Engineering?
The most cited paper in Biomedical Engineering is "Comparison of simple potential functions for simulating liquid water" (William L. Jorgensen, Jayaraman Chandrasekhar, Jeffry D. Madura et al., 1983), with 42,894 citations. Next come "Equation of State Calculations by Fast Computing Machines" (37,517) and "Molecular dynamics with coupling to an external bath" (31,502).
Showing 50 of 100 papers. Every paper with more than 6,912 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Comparison of simple potential functions for simulating liquid water William L. Jorgensen, Jayaraman Chandrasekhar, Jeffry D. Madura et al. · The Journal of Chemical Physics | 15 Jul 1983 | 42,894 |
| 2 | Equation of State Calculations by Fast Computing Machines N. Metropolis, Arianna W. Rosenbluth, M. N. Rosenbluth et al. · The Journal of Chemical Physics | Jun 1953 | 37,517 |
| 3 | Molecular dynamics with coupling to an external bath Herman J. C. Berendsen, Johan P. M. Postma, Wilfred F. van Gunsteren et al. · The Journal of Chemical Physics | 15 Oct 1984 | 31,502 |
| 4 | An improved technique for determining hardness and elastic modulus using load and displacement sensing indentation experiments W. C. Oliver, George M. Pharr · Journal of materials research/Pratt's guide to venture capital sources | Jun 1992 | 27,030 |
| 5 | Colorimetry of Total Phenolics with Phosphomolybdic-Phosphotungstic Acid Reagents Vernon L. Singleton, Joseph A. Rossi · American Journal of Enology and Viticulture | 1965 | 24,756 |
| 6 | A smooth particle mesh Ewald method Ulrich Essmann, L. Perera, Max L. Berkowitz et al. · The Journal of Chemical Physics | 15 Nov 1995 | 23,377 |
| 7 | A new generation of Ca2+ indicators with greatly improved fluorescence properties. Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry | Mar 1985 | 21,798 |
| 8 | Particle swarm optimization Riccardo Poli, James C. Kennedy, Tim Blackwell · Swarm Intelligence | 31 Jul 2007 | 21,401 |
| 9 | Physisorption of gases, with special reference to the evaluation of surface area and pore size distribution (IUPAC Technical Report) Matthias Thommes, Katsumi Kaneko, Alexander V. Neimark et al. · Pure and Applied Chemistry | 2 Jul 2015 | 20,886 |
| 10 | High resolution two-dimensional electrophoresis of proteins. Patrick H. O’Farrell · Journal of Biological Chemistry | May 1975 | 19,391 |
| 11 | DISC ELECTROPHORESIS – II METHOD AND APPLICATION TO HUMAN SERUM PROTEINS* Baruch J. Davis · Annals of the New York Academy of Sciences | Dec 1964 | 18,971 |
| 12 | Sensitivity and False Alarm Rate of a Fall Sensor in Long-Term Fall Detection in the Elderly Maarit Kangas, Raija Korpelainen, Irene Vikman et al. · Gerontology | 13 Aug 2014 | 18,953 |
| 13 | Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches Owen P. Hamill, Alain Marty, Erwin Neher et al. · Pflügers Archiv - European Journal of Physiology | Aug 1981 | 18,543 |
| 14 | ATHENA , ARTEMIS , HEPHAESTUS : data analysis for X-ray absorption spectroscopy using IFEFFIT Bruce Ravel, Matthew G. Newville · Journal of Synchrotron Radiation | 15 Jun 2005 | 16,947 |
| 15 | The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments Stephen Andrew Bustin, Vladimı́r Beneš, Jeremy A. Garson et al. · Clinical Chemistry | 26 Feb 2009 | 16,583 |
| 16 | NMRPipe: A multidimensional spectral processing system based on UNIX pipes Frank Delaglio, Stephan Grzesiek, Geerten W. Vuister et al. · Journal of Biomolecular NMR | Nov 1995 | 16,465 |
| 17 | Heart rate variability: Standards of measurement, physiological interpretation, and clinical use Marek Malik, J. Thomas Bigger, A. John Camm et al. · European Heart Journal | Mar 1996 | 15,375 |
| 18 | A survey on deep learning in medical image analysis Geert J. S. Litjens, Thijs Kooi, Babak Ehteshami Bejnordi et al. · Medical Image Analysis | 26 Jul 2017 | 15,309 |
| 19 | Nanostructured High‐Entropy Alloys with Multiple Principal Elements: Novel Alloy Design Concepts and Outcomes J.‐W. Yeh, Swe-Kai Chen, Sung‐Jan Lin et al. · Advanced Engineering Materials | May 2004 | 15,287 |
| 20 | Single-layer MoS2 transistors Branimir Radisavljevic, Aleksandra Rađenović, Jacopo Brivio et al. · Nature Nanotechnology | 30 Jan 2011 | 14,985 |
| 21 | The Properties of Gases and Liquids Robert Cortas Reid, THOMAS K. SHERWOOD, Robert E. Street · Physics Today | Apr 1959 | 14,172 |
| 22 | Matrix Elasticity Directs Stem Cell Lineage Specification Adam Jeffrey Engler, Shamik Sen, Hugh Lee Sweeney et al. · Cell | Aug 2006 | 13,994 |
| 23 | Graphene: Status and Prospects Andre K. Geim · Science | 18 Jun 2009 | 13,990 |
| 24 | Optical Coherence Tomography David T. Huang, Eric A. Swanson, Charles P. Lin et al. · Science | 22 Nov 1991 | 13,894 |
| 25 | Synthesis of graphene-based nanosheets via chemical reduction of exfoliated graphite oxide Sasha Stankovich, Dmitriy A. Dikin, Richard D. Piner et al. · Carbon | 8 Mar 2007 | 13,883 |
| 26 | A survey on sensor networks Ian Fuat Akyildiz, Weilian Su, Yogesh Sankarasubramaniam et al. · IEEE Communications Magazine | Aug 2002 | 13,712 |
| 27 | Antioxidant Determinations by the Use of a Stable Free Radical Marsden S. Blois · Nature | Apr 1958 | 13,038 |
| 28 | Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids Laura C. Green, David A. Wagner, Joseph A. Glogowski et al. · Analytical Biochemistry | Oct 1982 | 12,147 |
| 29 | Improved Synthesis of Graphene Oxide Daniela C. Marcano, Dmitry V. Kosynkin, Jacob M. Berlin et al. · ACS Nano | 22 Jul 2010 | 12,017 |
| 30 | A training algorithm for optimal margin classifiers Bernhard E. Boser, Isabelle Guyon, Vladimir N. Vapnik | Jul 1992 | 11,724 |
| 31 | Surface plasmon subwavelength optics William L. Barnes, Alain Dereux, Thomas W. Ebbesen · Nature | Aug 2003 | 11,670 |
| 32 | The chemistry of graphene oxide Daniel R. Dreyer, Sungjin Park, Christopher W. Bielawski et al. · Chemical Society Reviews | 3 Nov 2009 | 11,601 |
| 33 | Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa Hermann Schägger, Gebhard von Jagow · Analytical Biochemistry | Nov 1987 | 11,542 |
| 34 | Large-Area Synthesis of High-Quality and Uniform Graphene Films on Copper Foils Xuesong Li, Weiwei Cai, Jinho An et al. · Science | 7 May 2009 | 11,244 |
| 35 | The Optical Properties of Metal Nanoparticles: The Influence of Size, Shape, and Dielectric Environment K. Lance Kelly, Eduardo A. Coronado, Lin Lin Zhao et al. · The Journal of Physical Chemistry B | 21 Dec 2002 | 10,577 |
| 36 | Orbital angular momentum of light and the transformation of Laguerre-Gaussian laser modes Leslie Allen, Marco W. Beijersbergen, R. J. C. Spreeuw et al. · Physical Review A | Jun 1992 | 10,522 |
| 37 | Large-scale pattern growth of graphene films for stretchable transparent electrodes Keun‐Soo Kim, Yüe Zhao, Houk Jang et al. · Nature | 14 Jan 2009 | 10,482 |
| 38 | Light Propagation with Phase Discontinuities: Generalized Laws of Reflection and Refraction Nanfang Yu, Patrice Genevet, Mikhail A. Kats et al. · Science | Sep 2011 | 10,346 |
| 39 | Carbon Nanotubes--the Route Toward Applications Ray H. Baughman, Anvar A. Zakhidov, Walt A. de Heer · Science | 2 Aug 2002 | 10,268 |
| 40 | An Introduction To Compressive Sampling Emmanuel J. Candès, Michael B. Wakin · IEEE Signal Processing Magazine | Mar 2008 | 10,167 |
| 41 | Phonons and related crystal properties from density-functional perturbation theory Stefano Baroni, Stefano de Gironcoli, Andrea Dal Corso et al. · Reviews of Modern Physics | 6 Jul 2001 | 10,098 |
| 42 | Strong localization of photons in certain disordered dielectric superlattices Sajeev John · Physical Review Letters | 8 Jun 1987 | 10,049 |
| 43 | PLS-regression: a basic tool of chemometrics Svante Wold, Michael Sjöstróm, Lennart Eriksson · Chemometrics and Intelligent Laboratory Systems | Oct 2001 | 10,019 |
| 44 | Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria Chris H. Polman, Stephen C. Reingold, Brenda Banwell et al. · Annals of Neurology | 11 Jan 2011 | 9,914 |
| 45 | Signal Recovery From Random Measurements Via Orthogonal Matching Pursuit Joel A. Tropp, Anna C. Gilbert · IEEE Transactions on Information Theory | Dec 2007 | 9,832 |
| 46 | New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening Philip Skehan, Ritsa Storeng, Dominic A. Scudiero et al. · JNCI Journal of the National Cancer Institute | 4 Jul 1990 | 9,830 |
| 47 | Tissue Engineering Róbert Langer, Joseph P. Vacanti · Science | 14 May 1993 | 9,666 |
| 48 | The origins and the future of microfluidics George M. Whitesides · Nature | Jul 2006 | 9,641 |
| 49 | How useful is SBF in predicting in vivo bone bioactivity? Tadashi Kokubo, Hiroaki Takadama · Biomaterials | Feb 2006 | 9,606 |
| 50 | nnU-Net: a self-configuring method for deep learning-based biomedical image segmentation Fabian Isensee, Paul F. Jaeger, Simon A. A. Kohl et al. · Nature Methods | 7 Dec 2020 | 9,588 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.