Subfield · Clinical Biochemistry
Most cited papers in Clinical Biochemistry
What are the most cited papers in Clinical Biochemistry?
The most cited paper in Clinical Biochemistry is "Antibiotic Susceptibility Testing by a Standardized Single Disk Method" (Alfred W. Bauer, William M. M. Kirby, J. C. Sherris et al., 1966), with 18,626 citations. Next come "Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees." (11,497) and "Biochemistry and molecular cell biology of diabetic complications" (9,153).
Showing 50 of 100 papers. Every paper with more than 2,070 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Antibiotic Susceptibility Testing by a Standardized Single Disk Method Alfred W. Bauer, William M. M. Kirby, J. C. Sherris et al. · American Journal of Clinical Pathology | Apr 1966 | 18,626 |
| 2 | Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees. Koichiro Tamura, M Nei · Molecular Biology and Evolution | May 1993 | 11,497 |
| 3 | Biochemistry and molecular cell biology of diabetic complications Michael Brownlee · Nature | 13 Dec 2001 | 9,153 |
| 4 | Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study IRENE M. STRATTON · BMJ | 12 Aug 2000 | 9,131 |
| 5 | Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent Jozef Sedlak, Raymond H. Lindsay · Analytical Biochemistry | 1968 | 8,107 |
| 6 | Report of the Ad Hoc Committee on Reconciliation of Approaches to Bacterial Systematics L G Wayne, William E. Moore, Erko Stackebrandt et al. · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY | Oct 1987 | 7,348 |
| 7 | Methods for in vitro evaluating antimicrobial activity: A review Mounyr Balouiri, Moulay Sadiki, Saâd Ibnsouda Koraichi · Journal of Pharmaceutical Analysis | 2 Dec 2015 | 7,292 |
| 8 | CDC/NHSN surveillance definition of health care–associated infection and criteria for specific types of infections in the acute care setting Teresa C Horan, Mary L. Andrus, Margaret A. Dudeck · American Journal of Infection Control | Jun 2008 | 6,712 |
| 9 | Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases Michael T. S. Lin, M. Flint Beal · Nature | Oct 2006 | 6,522 |
| 10 | The Thiobarbituric Acid Assay of Sialic Acids Leonard Warren · Journal of Biological Chemistry | Aug 1959 | 6,453 |
| 11 | Neuroinflammation in Alzheimer's disease Michael Thomas Heneka et al. · The Lancet Neurology | 16 Mar 2015 | 6,318 |
| 12 | ILAE Official Report: A practical clinical definition of epilepsy Robert S. Fisher, Carlos Alberto Acevedo, Alexis A. Arzimanoglou et al. · Epilepsia | Apr 2014 | 6,110 |
| 13 | Staphylococcus aureus Infections F D Lowy · New England Journal of Medicine | 20 Aug 1998 | 6,083 |
| 14 | The Epidemiology of Sepsis in the United States from 1979 through 2000 Greg S. Martin, David M. Mannino, Stephanie Eaton et al. · New England Journal of Medicine | 16 Apr 2003 | 5,909 |
| 15 | C-Reactive Protein and Other Markers of Inflammation in the Prediction of Cardiovascular Disease in Women Paul M. Ridker, Charles H. Hennekens, Julie E. Buring et al. · New England Journal of Medicine | 23 Mar 2000 | 5,889 |
| 16 | Oxidative Stress and Diabetic Complications Ferdinando Giacco, Michael Brownlee · Circulation Research | 28 Oct 2010 | 5,514 |
| 17 | Introducing EzTaxon-e: a prokaryotic 16S rRNA gene sequence database with phylotypes that represent uncultured species Ok-Sun Kim, Yong‐Joon Cho, Kihyun Lee et al. · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY | 25 Nov 2011 | 5,292 |
| 18 | Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America Helen W. Boucher, George H. Talbot, John S. Bradley et al. · Clinical Infectious Diseases | 26 Nov 2008 | 5,020 |
| 19 | DNA–DNA hybridization values and their relationship to whole-genome sequence similarities Johan Goris, Konstantinos T. Konstantinidis, Joel A. Klappenbach et al. · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY | 2007 | 4,922 |
| 20 | Tetracycline Antibiotics: Mode of Action, Applications, Molecular Biology, and Epidemiology of Bacterial Resistance Ian Chopra, Marilyn C. Roberts · Microbiology and Molecular Biology Reviews | Jun 2001 | 4,554 |
| 21 | Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage Takeshi Nishikawa, Diane Edelstein, Xue Liang Du et al. · Nature | Apr 2000 | 4,302 |
| 22 | Release of chromatin protein HMGB1 by necrotic cells triggers inflammation Paola Scaffidi, Tom Misteli, Marco Emilio Bianchi · Nature | 11 Jul 2002 | 4,239 |
| 23 | Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin Lyudmila V. Borovikova, Svetlana Ivanova, Minghuang Zhang et al. · Nature | May 2000 | 4,235 |
| 24 | Determination of minimum inhibitory concentrations Jennifer M. Andrews · Journal of Antimicrobial Chemotherapy | Jul 2001 | 4,142 |
| 25 | Glutamate uptake Niels Christian Danbolt · Progress in Neurobiology | Sep 2001 | 4,090 |
| 26 | Dietary Advanced Glycation End Products and Their Potential Role in Cardiometabolic Disease in Children Anshu Gupta, Jaime Uribarri · Hormone Research in Paediatrics | 2016 | 4,017 |
| 27 | Mitochondrial Fission, Fusion, and Stress Richard J. Youle, Alexander M. van der Bliek · Science | 30 Aug 2012 | 3,720 |
| 28 | Role of Oxidative Stress in Development of Complications in Diabetes John Baynes · Diabetes | Apr 1991 | 3,719 |
| 29 | Open-access bacterial population genomics: BIGSdb software, the PubMLST.org website and their applications Keith A. Jolley, James E. Bray, Martin C. J. Maiden · Wellcome Open Research | 24 Sep 2018 | 3,700 |
| 30 | Mitochondria: In Sickness and in Health Jodi M. Nunnari, Anu Suomalainen · Cell | Mar 2012 | 3,549 |
| 31 | Clinical Practice Guideline for the Use of Antimicrobial Agents in Neutropenic Patients with Cancer: 2010 Update by the Infectious Diseases Society of America Alison G. Freifeld, Eric J. Bow, Kent A. Sepkowitz et al. · Clinical Infectious Diseases | 22 Jan 2011 | 3,477 |
| 32 | ResFinder 4.0 for predictions of phenotypes from genotypes Valeria Bortolaia et al. · Journal of Antimicrobial Chemotherapy | 16 Jul 2020 | 3,475 |
| 33 | Targeting the KEAP1-NRF2 System to Prevent Kidney Disease Progression Masahiro Nezu, Norio Suzuki, Masayuki P. Yamamoto · American Journal of Nephrology | 2017 | 3,459 |
| 34 | HMG-1 as a Late Mediator of Endotoxin Lethality in Mice Haichao Wang, Ona Bloom, Minghuang Zhang et al. · Science | 9 Jul 1999 | 3,422 |
| 35 | Reliability of diagnosing bacterial vaginosis is improved by a standardized method of gram stain interpretation Rachel Nugent, Marijane A. Krohn, Sharon L. Hillier · Journal of Clinical Microbiology | Feb 1991 | 3,402 |
| 36 | Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America Guidelines for Developing an Institutional Program to Enhance Antimicrobial Stewardship Timothy H. Dellit, Robert C. Owens, John E. McGowan et al. · Clinical Infectious Diseases | 19 Dec 2006 | 3,400 |
| 37 | Robbins and Cotran Pathologic Basis of Disease Syed A. Hoda, Raza S. Hoda · American Journal of Clinical Pathology | 13 Aug 2020 | 3,387 |
| 38 | CARD 2020: antibiotic resistome surveillance with the comprehensive antibiotic resistance database Brian P. Alcock et al. · Nucleic Acids Research | 8 Oct 2019 | 3,385 |
| 39 | Antimicrobial resistance: a global multifaceted phenomenon Francesca Prestinaci, Patrizio Pezzotti, Annalisa Pantosti · Pathogens and Global Health | 7 Sep 2015 | 3,353 |
| 40 | Resveratrol Reduces the Proinflammatory Effects and Lipopolysaccharide- Induced Expression of HMGB1 and TLR4 in RAW264.7 Cells Ying Yang, Shuping Li, Qiao Yang et al. · Cellular Physiology and Biochemistry | 2014 | 3,256 |
| 41 | A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine Douglas C. Wallace · Annual Review of Genetics | 19 Jul 2005 | 3,201 |
| 42 | Diabetes, oxidative stress, and antioxidants: A review Alice C. Maritim, Ruth A. Sanders, J. B. Watkins · Journal of Biochemical and Molecular Toxicology | 2003 | 3,140 |
| 43 | Implementing an Antibiotic Stewardship Program: Guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America Tamar F. Barlam et al. · Clinical Infectious Diseases | 13 Apr 2016 | 3,087 |
| 44 | Mitochondrial Diseases in Man and Mouse Douglas C. Wallace · Science | 5 Mar 1999 | 3,076 |
| 45 | Multilocus Sequence Typing for Characterization of Methicillin-Resistant and Methicillin-Susceptible Clones ofStaphylococcus aureus Mark C. Enright, Nicholas Day, Catrin E. Davies et al. · Journal of Clinical Microbiology | Mar 2000 | 3,050 |
| 46 | Creatine and Creatinine Metabolism Markus Wyss, Rima F Kaddurah-Daouk · Physiological Reviews | Jul 2000 | 2,964 |
| 47 | Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism* Béatrice Desvergne, Walter Wahli · Endocrine Reviews | Oct 1999 | 2,903 |
| 48 | Mechanisms of Diabetic Complications Josephine Maree Forbes, Mark Emmanuel Cooper · Physiological Reviews | 2013 | 2,890 |
| 49 | The Crisis in Antibiotic Resistance Harold C. Neu · Science | 21 Aug 1992 | 2,858 |
| 50 | A RAPID AND PRECISE METHOD FOR THE DETERMINATION OF UREA Janet Fawcett, John E. Scott · Journal of Clinical Pathology | Mar 1960 | 2,803 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.