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Most cited papers in Endocrine and Autonomic Systems

What are the most cited papers in Endocrine and Autonomic Systems?

The most cited paper in Endocrine and Autonomic Systems is "Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids" (Laura C. Green, David A. Wagner, Joseph A. Glogowski et al., 1982), with 12,147 citations. Next come "The Occurrence of Sleep-Disordered Breathing among Middle-Aged Adults" (10,268) and "Ghrelin is a growth-hormone-releasing acylated peptide from stomach" (8,535).

Showing 50 of 100 papers. Every paper with more than 2,428 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids Laura C. Green, David A. Wagner, Joseph A. Glogowski et al. · Analytical Biochemistry Oct 1982 12,147
2 The Occurrence of Sleep-Disordered Breathing among Middle-Aged Adults Terry B Young, Mari Palta, Jerome A. Dempsey et al. · New England Journal of Medicine Open access 29 Apr 1993 10,268
3 Ghrelin is a growth-hormone-releasing acylated peptide from stomach Masayasu Kojima, Hiroshi Hosoda, Yukari Date et al. · Nature Dec 1999 8,535
4 The L-Arginine-Nitric Oxide Pathway Franklin H. Epstein, Salvador Moncada, Annie Higgs · New England Journal of Medicine 30 Dec 1993 6,737
5 Protective and Damaging Effects of Stress Mediators Bruce S. McEwen · New England Journal of Medicine 15 Jan 1998 6,716
6 Hallmarks of aging: An expanding universe Carlos López-Otı́n, Marı́a A. Blasco, Linda Partridge et al. · Cell Open access 2023 6,477
7 Central nervous system control of food intake Michael W. Schwartz, Stephen C. Woods, Daniel Porte et al. · Nature Apr 2000 6,471
8 Serum Immunoreactive-Leptin Concentrations in Normal-Weight and Obese Humans Robert V. Considine, Madhur K. Sinha, Mark L. Heiman et al. · New England Journal of Medicine Feb 1996 6,381
9 The structure of the nervous system of the nematode Caenorhabditis elegans JG White, Eileen Southgate, J. Nichol Thomson et al. · Philosophical transactions of the Royal Society of London. Series B, Biological sciences 12 Nov 1986 5,884
10 Orexins and Orexin Receptors: A Family of Hypothalamic Neuropeptides and G Protein-Coupled Receptors that Regulate Feeding Behavior Takeshi Sakurai et al. · Cell Open access Feb 1998 5,551
11 Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly Joseph S. Beckman, Willem Hendrik Koppenol · American Journal of Physiology-Cell Physiology Nov 1996 5,539
12 Adipose Tissue as an Endocrine Organ Erin E. Kershaw, Jeffrey S. Flier · The Journal of Clinical Endocrinology & Metabolism Jun 2004 5,530
13 Leptin and the regulation of body weight in mammals Jeffrey M. Friedman, Jeffrey L. Halaas · Nature Oct 1998 5,424
14 Inflamm‐aging: An Evolutionary Perspective on Immunosenescence Claudio Franceschi, Massimiliano Bonafè, Silvana Valensin et al. · Annals of the New York Academy of Sciences Jun 2000 5,391
15 Increased oxidative stress in obesity and its impact on metabolic syndrome Shigetada Furukawa, Takuya Fujita, Michio Shimabukuro et al. · Journal of Clinical Investigation Open access 15 Dec 2004 5,349
16 Rules for Scoring Respiratory Events in Sleep: Update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events Richard Barnett Berry, Rohit Budhiraja, Daniel J. Gottlieb et al. · Journal of Clinical Sleep Medicine Open access 12 Oct 2012 5,340
17 Prospective Study of the Association between Sleep-Disordered Breathing and Hypertension Paul E. Peppard, Terry B Young, Mari Palta et al. · New England Journal of Medicine Open access 11 May 2000 5,015
18 The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity Toshimasa Yamauchi et al. · Nature Medicine Aug 2001 4,950
19 Bronchopulmonary Dysplasia Alan Hall Jobe, Eduardo Bancalari · American Journal of Respiratory and Critical Care Medicine Jun 2001 4,884
20 Paradoxical Decrease of an Adipose-Specific Protein, Adiponectin, in Obesity Yukio Arita, Shinji Kihara, Noriyuki Bob Ouchi et al. · Biochemical and Biophysical Research Communications Apr 1999 4,880
21 The hormone resistin links obesity to diabetes Claire M. Steppan, Shannon Terrell Bailey, Savitha Bhat et al. · Nature 2001 4,790
22 Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study José María Marín, Santiago J. Carrizo, Eugenio E. Vicente et al. · The Lancet Mar 2005 4,704
23 Increased Prevalence of Sleep-Disordered Breathing in Adults P. E. Peppard, Terry B Young, Jodi H. Barnet et al. · American Journal of Epidemiology Open access 14 Apr 2013 4,673
24 Structural and functional features of central nervous system lymphatic vessels Antoine Louveau, Igor Smirnov, Timothy Keyes et al. · Nature Open access 29 May 2015 4,467
25 Coordination of circadian timing in mammals Steven M. Reppert, David R. Weaver · Nature Aug 2002 4,422
26 Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis Adam Benjafield, Najib Ayas, Peter R. Eastwood et al. · The Lancet Respiratory Medicine Open access 9 Jul 2019 4,294
27 Epidemiology of Obstructive Sleep Apnea: A Population Health Perspective Terry B Young, Paul E. Peppard, Daniel J. Gottlieb · American Journal of Respiratory and Critical Care Medicine May 2002 4,280
28 Effects of the obese Gene Product on Body Weight Regulation in ob / ob Mice Mary Ann Pelleymounter, Mary Jane Cullen, Mary Beth Baker et al. · Science 28 Jul 1995 4,035
29 Receptors for Purines and Pyrimidines Geoffrey Burnstock, Alexei Verkhratsky Book chapter 2012 3,980
30 Ghrelin induces adiposity in rodents Matthias H. Tschöp, David L. Smiley, Mark L. Heiman · Nature Oct 2000 3,964
31 The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity Luı́s de Lecea, Thomas S. Kilduff, Christelle Peyron et al. · Proceedings of the National Academy of Sciences Open access 6 Jan 1998 3,912
32 Rapamycin fed late in life extends lifespan in genetically heterogeneous mice David E. Harrison, Randy Strong, Zelton Dave Sharp et al. · Nature Open access Jul 2009 3,836
33 Epidemiology of insomnia: what we know and what we still need to learn Maurice Moyses Ohayon · Sleep Medicine Reviews May 2002 3,775
34 Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects Margherita Maffei, Jeffrey L. Halaas, Éric Ravussin et al. · Nature Medicine Nov 1995 3,765
35 The inflammatory reflex Kevin J. Tracey · Nature Dec 2002 3,734
36 Phototransduction by Retinal Ganglion Cells That Set the Circadian Clock David M. Berson, Felice A. Dunn, Motoharu Takao · Science 8 Feb 2002 3,689
37 Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change Jens C. Pruessner, Clemens Kirschbaum, Gunther Meinlschmid et al. · Psychoneuroendocrinology 4 Mar 2003 3,677
38 Post-embryonic cell lineages of the nematode, Caenorhabditis elegans J.E. Sulston, H. Robert Horvitz · Developmental Biology Mar 1977 3,621
39 Cardiovascular neural regulation explored in the frequency domain. Alberto Malliani, M. Pagani, Federico Lombardi et al. · Circulation Open access Aug 1991 3,589
40 Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. Gökhan S. Hotamışlıgil, Peter Arner, J F Caro et al. · Journal of Clinical Investigation Open access May 1995 3,545
41 Solid-State Light Sources Getting Smart E. Fred Schubert, Jong Kyu Kim · Science 26 May 2005 3,533
42 Identification and expression cloning of a leptin receptor, OB-R Louis A. Tartaglia, Marlene Dembski, Xun Weng et al. · Cell Open access Dec 1995 3,513
43 Neurons Containing Hypocretin (Orexin) Project to Multiple Neuronal Systems Christelle Peyron, Devin K. Tighe, Anthony N. van den Pol et al. · Journal of Neuroscience Open access Dec 1998 3,495
44 A role for ghrelin in the central regulation of feeding Masamitsu Nakazato, Noboru Murakami, Yukari Date et al. · Nature 2001 3,461
45 Anorexigenic and Orexigenic Hormone Modulation of Mammalian Target of Rapamycin Complex 1 Activity and the Regulation of Hypothalamic Agouti-Related Protein mRNA Expression Kenneth R. Watterson, Dawn Bestow, Jennifer R. Gallagher et al. · Neurosignals Open access 28 Mar 2012 3,395
46 Neural regulation of endocrine and autonomic stress responses Yvonne M. Ulrich‐Lai, James P. Herman · Nature reviews. Neuroscience ReviewOpen access 13 May 2009 3,354
47 Recombinant Mouse OB Protein: Evidence for a Peripheral Signal Linking Adiposity and Central Neural Networks L. Arthur Campfield, Françoise J. Smith, Yves Guisez et al. · Science 28 Jul 1995 3,280
48 The Triad of Sleep Apnea, Hypertension, and Chronic Kidney Disease: A Spectrum of Common Pathology Fahad Aziz, Kunal R. Chaudhary · Cardiorenal Medicine Open access 4 Nov 2016 3,278
49 Obesity and insulin resistance Barbara B. Kahn, Jeffrey S. Flier · Journal of Clinical Investigation Open access 15 Aug 2000 3,247
50 Adipocytokines: mediators linking adipose tissue, inflammation and immunity Herbert Tilg, Alexander Rupert Moschen · Nature reviews. Immunology Review 22 Sep 2006 3,217

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.