Subfield · Internal Medicine
Most cited papers in Internal Medicine
What are the most cited papers in Internal Medicine?
The most cited paper in Internal Medicine is "Correspondence - Tranexamic acid for traumatic brain injury" (Marina Romanello et al., 2005), with 11,912 citations. Next come "Dabigatran versus Warfarin in Patients with Atrial Fibrillation" (11,272) and "Refining Clinical Risk Stratification for Predicting Stroke and Thromboembolism in Atrial Fibrillation Using a Novel Risk Factor-Based Approach" (6,816).
Showing 50 of 96 papers. Every paper with more than 1,324 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Correspondence - Tranexamic acid for traumatic brain injury Marina Romanello et al. · London School of Economics and Political Science Theses Online (London School of Economics and Political Science) | 2005 | 11,912 |
| 2 | Dabigatran versus Warfarin in Patients with Atrial Fibrillation Stuart J. Connolly, Michael D. Ezekowitz, Salim Yusuf et al. · New England Journal of Medicine | 30 Aug 2009 | 11,272 |
| 3 | Refining Clinical Risk Stratification for Predicting Stroke and Thromboembolism in Atrial Fibrillation Using a Novel Risk Factor-Based Approach Gregory Y.H. Lip, Robby Nieuwlaat, Ron Pisters et al. · CHEST Journal | 18 Sep 2009 | 6,816 |
| 4 | Antithrombotic Therapy for VTE Disease Clive Kearon, Elie A. Akl, Anthony James Comerota et al. · CHEST Journal | Feb 2012 | 6,164 |
| 5 | Prevention of Venous Thromboembolism William H Geerts, Graham Frederick Pineo, John A. Heit et al. · CHEST Journal | Sep 2004 | 5,923 |
| 6 | Guidelines for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack Walter N. Kernan, Bruce I Ovbiagele, Henry Richard Black et al. · Stroke | May 2014 | 5,218 |
| 7 | 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS) Stavros Konstantinides et al. · European Heart Journal | 31 Aug 2019 | 4,992 |
| 8 | Validation of Clinical Classification Schemes for Predicting Stroke Brian F. Gage, Amy D. Waterman, William D. Shannon et al. · JAMA | 13 Jun 2001 | 4,866 |
| 9 | Angiogenic Factors Judah Folkman, Michael Klagsbrun · Science | 23 Jan 1987 | 3,784 |
| 10 | Definition of major bleeding in clinical investigations of antihemostatic medicinal products in surgical patients Sam Schulman, Ulf Angerås, David Bergqvist et al. · Journal of Thrombosis and Haemostasis | 30 Oct 2009 | 3,778 |
| 11 | Angiogenesis in life, disease and medicine Peter Carmeliet · Nature | Dec 2005 | 3,495 |
| 12 | 2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism Authors Task Force Members et al. · European Heart Journal | 29 Aug 2014 | 3,165 |
| 13 | A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis SR Poort, FR Rosendaal, PH Reitsma et al. · Blood | 15 Nov 1996 | 3,128 |
| 14 | COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-Up Behnood Bikdeli et al. · Journal of the American College of Cardiology | 17 Apr 2020 | 2,956 |
| 15 | Acute pulmonary embolism: clinical outcomes in the International Cooperative Pulmonary Embolism Registry (ICOPER) Samuel Zachary Goldhaber, Luigi Visani, Marisa De Rosa · The Lancet | Apr 1999 | 2,880 |
| 16 | Guidelines on the diagnosis and management of acute pulmonary embolism Authors/Task Force Members et al. · European Heart Journal | 30 Aug 2008 | 2,837 |
| 17 | Prevention of VTE in Nonsurgical Patients Susan R. Kahn, Wendy Lim, Andrew S Dunn et al. · CHEST Journal | Feb 2012 | 2,698 |
| 18 | Trends in the Incidence of Deep Vein Thrombosis and Pulmonary Embolism Marc D. Silverstein, John A. Heit, David N. Mohr et al. · Archives of Internal Medicine | 23 Mar 1998 | 2,678 |
| 19 | Dabigatran versus Warfarin in the Treatment of Acute Venous Thromboembolism Sam Schulman, Clive Kearon, Ajay K. Kakkar et al. · New England Journal of Medicine | 6 Dec 2009 | 2,584 |
| 20 | Low-Molecular-Weight Heparin versus a Coumarin for the Prevention of Recurrent Venous Thromboembolism in Patients with Cancer Agnes Y. Y. Lee, Mark N. Levine, Ross Ian Baker et al. · New England Journal of Medicine | 9 Jul 2003 | 2,541 |
| 21 | Oral Apixaban for the Treatment of Acute Venous Thromboembolism Giancarlo Agnelli, Harry Roger Buller, Alexander T. Cohen et al. · New England Journal of Medicine | Jul 2013 | 2,328 |
| 22 | The Epidemiology of Venous Thromboembolism Richard H. R. White · Circulation | 17 Jun 2003 | 2,326 |
| 23 | Clinical Applications of Research on Angiogenesis Judah Folkman · New England Journal of Medicine | 28 Dec 1995 | 2,289 |
| 24 | Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives Jeng‐Jiann Chiu, Shu Chien · Physiological Reviews | 2011 | 2,273 |
| 25 | Development and validation of a predictive model for chemotherapy-associated thrombosis Alok A. Khorana, Nicole M. Kuderer, Eva Culakova et al. · Blood | 23 Jan 2008 | 2,245 |
| 26 | Management of Massive and Submassive Pulmonary Embolism, Iliofemoral Deep Vein Thrombosis, and Chronic Thromboembolic Pulmonary Hypertension Michael R. Jaff, Michael Sean McMurtry, Stephen L. Archer et al. · Circulation | 22 Mar 2011 | 2,242 |
| 27 | Prevalence, Age Distribution, and Gender of Patients With Atrial Fibrillation William M. Feinberg · Archives of Internal Medicine | 13 Mar 1995 | 2,190 |
| 28 | Risk Factors for Deep Vein Thrombosis and Pulmonary Embolism John A. Heit, Marc D. Silverstein, David N. Mohr et al. · Archives of Internal Medicine | 27 Mar 2000 | 2,186 |
| 29 | Platelet Activation and Atherothrombosis Giovanni Davı̀, Carlo Patrono · New England Journal of Medicine | 12 Dec 2007 | 2,157 |
| 30 | Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy Corrado Lodigiani, G. Iapichino, Luca Carenzo et al. · Thrombosis Research | 23 Apr 2020 | 2,152 |
| 31 | Prevention of VTE in Nonorthopedic Surgical Patients Michael K. Gould, David García, Sherry M. Wren et al. · CHEST Journal | Feb 2012 | 2,137 |
| 32 | The Long-Term Clinical Course of Acute Deep Venous Thrombosis Paolo Prandoni, Anthonie W.A. Lensing, Alberto Cogo et al. · Annals of Internal Medicine | Jul 1996 | 2,119 |
| 33 | A Method to Determine the Optimal Intensity of Oral Anticoagulant Therapy Frits R. Rosendaal, Suzanne C. Cannegieter, Felix J.M. van der Meer et al. · Thrombosis and Haemostasis | 1993 | 2,077 |
| 34 | Antithrombotic Therapy for Venous Thromboembolic Disease Thomas M. Hyers, Giancarlo Agnelli, Russell Douglas Hull et al. · CHEST Journal | 2001 | 2,051 |
| 35 | Antithrombotic Therapy for Venous Thromboembolic Disease Clive Kearon, Susan R. Kahn, Giancarlo Agnelli et al. · CHEST Journal | Jun 2008 | 2,002 |
| 36 | Thrombosis as an intravascular effector of innate immunity Bernd Engelmann, Steffen Maßberg · Nature reviews. Immunology | 7 Dec 2012 | 1,969 |
| 37 | Malignancies, Prothrombotic Mutations, and the Risk of Venous Thrombosis Jeanet W. Blom · JAMA | 8 Feb 2005 | 1,966 |
| 38 | HAEMOSTATIC FUNCTION AND ISCHAEMIC HEART DISEASE: PRINCIPAL RESULTS OF THE NORTHWICK PARK HEART STUDY T W Meade, Milica Brozović, Ranjan Chakrabarti et al. · The Lancet | Sep 1986 | 1,956 |
| 39 | Prevention of VTE in Orthopedic Surgery Patients Yngve T Falck-Ytter, Charles W. Francis, Norman A. Johanson et al. · CHEST Journal | Feb 2012 | 1,939 |
| 40 | Revision of the CEAP classification for chronic venous disorders: Consensus statement Bo Eklöf, Robert Bruce Rutherford, John J. Bergan et al. · Journal of Vascular Surgery | Dec 2004 | 1,927 |
| 41 | Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia Songping Cui, Shuo Chen, Xiunan Li et al. · Journal of Thrombosis and Haemostasis | 9 Apr 2020 | 1,892 |
| 42 | Recurrent venous thromboembolism and bleeding complications during anticoagulant treatment in patients with cancer and venous thrombosis Paolo Prandoni, Anthonie W.A. Lensing, Andrea Piccioli et al. · Blood | 30 Oct 2002 | 1,868 |
| 43 | A Platelet-Dependent Serum Factor That Stimulates the Proliferation of Arterial Smooth Muscle Cells In Vitro Russell Ross, John Glomset, Beverly Kariya et al. · Proceedings of the National Academy of Sciences | Apr 1974 | 1,858 |
| 44 | Incidence of Chronic Thromboembolic Pulmonary Hypertension after Pulmonary Embolism Vittorio Pengo, Anthonie W.A. Lensing, Martin H. Prins et al. · New England Journal of Medicine | 26 May 2004 | 1,843 |
| 45 | Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo Marie-Luise von Brühl et al. · The Journal of Experimental Medicine | 26 Mar 2012 | 1,840 |
| 46 | Transluminal Treatment of Arteriosclerotic Obstruction Charles T. Dotter, Melvin P. Judkins · Circulation | Nov 1964 | 1,772 |
| 47 | A Clinical Trial of Vena Caval Filters in the Prevention of Pulmonary Embolism in Patients with Proximal Deep-Vein Thrombosis Hervé Decousus, Alain Leizorovicz, Florence Parent et al. · New England Journal of Medicine | 12 Feb 1998 | 1,721 |
| 48 | Fibrinolysis for Patients with Intermediate-Risk Pulmonary Embolism Guy Meyer et al. · New England Journal of Medicine | 9 Apr 2014 | 1,714 |
| 49 | Thromboembolism is a leading cause of death in cancer patients receiving outpatient chemotherapy Alok A. Khorana, C. W. Francis, Eva Culakova et al. · Journal of Thrombosis and Haemostasis | 21 Feb 2007 | 1,690 |
| 50 | Derivation of a Simple Clinical Model to Categorize Patients Probability of Pulmonary Embolism: Increasing the Models Utility with the SimpliRED D-dimer David Anderson, Marc Rodger, Jeffrey Ginsberg et al. · Thrombosis and Haemostasis | 2000 | 1,671 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.