Most cited papers in 3D Printing in Biomedical Research
What are the most cited papers in 3D Printing in Biomedical Research?
The most cited paper in 3D Printing in Biomedical Research is "A new generation of Ca2+ indicators with greatly improved fluorescence properties." (Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien, 1985), with 21,798 citations. Next come "Matrix Elasticity Directs Stem Cell Lineage Specification" (13,994) and "New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening" (9,830).
Showing 50 of 99 papers. Every paper with more than 1,740 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | A new generation of Ca2+ indicators with greatly improved fluorescence properties. Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry | Mar 1985 | 21,798 |
| 2 | Matrix Elasticity Directs Stem Cell Lineage Specification Adam Jeffrey Engler, Shamik Sen, Hugh Lee Sweeney et al. · Cell | Aug 2006 | 13,994 |
| 3 | New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening Philip Skehan, Ritsa Storeng, Dominic A. Scudiero et al. · JNCI Journal of the National Cancer Institute | 4 Jul 1990 | 9,830 |
| 4 | Tissue Engineering Róbert Langer, Joseph P. Vacanti · Science | 14 May 1993 | 9,666 |
| 5 | Additive manufacturing (3D printing): A review of materials, methods, applications and challenges Tuan Ngo, Alireza Hosseinzadeh Kashani, Gabriele Imbalzano et al. · Composites Part B Engineering | 13 Feb 2018 | 8,400 |
| 6 | Alginate: Properties and biomedical applications Kuen Yong Lee, David J. Mooney · Progress in Polymer Science | 7 Jul 2011 | 8,099 |
| 7 | 3D bioprinting of tissues and organs Sean V. Murphy, Anthony Atala · Nature Biotechnology | Aug 2014 | 7,011 |
| 8 | THF EARLY STAGES OF ABSORPTION OF INJECTED HORSERADISH PEROXIDASE IN THE PROXIMAL TUBULES OF MOUSE KIDNEY: ULTRASTRUCTURAL CYTOCHEMISTRY BY A NEW TECHNIQUE Richard C. Graham, Morris J. Karnovsky · Journal of Histochemistry & Cytochemistry | Apr 1966 | 6,512 |
| 9 | Tissue Cells Feel and Respond to the Stiffness of Their Substrate Dennis E. Discher, Paul A. Janmey, Yu-Li Wang · Science | 18 Nov 2005 | 6,452 |
| 10 | Hydrogels for Tissue Engineering Kuen Yong Lee, David J. Mooney · Chemical Reviews | 31 May 2001 | 5,279 |
| 11 | Hydrogels for tissue engineering: scaffold design variables and applications Jeanie L. Drury, David J. Mooney · Biomaterials | 30 Jun 2003 | 5,130 |
| 12 | Scaffolds in tissue engineering bone and cartilage Dietmar Werner Hutmacher · Biomaterials | Dec 2000 | 4,998 |
| 13 | Rapid colorimetric assay for cell growth and survival François Denizot, Rita Lang · Journal of Immunological Methods | May 1986 | 4,918 |
| 14 | Hydrogels for biomedical applications Allan S. Hoffman · Advanced Drug Delivery Reviews | 2002 | 4,833 |
| 15 | Cellular Motility Driven by Assembly and Disassembly of Actin Filaments Thomas Dean Pollard, Gary G. Borisy · Cell | Feb 2003 | 4,257 |
| 16 | Reconstituting Organ-Level Lung Functions on a Chip Dongeun Huh, Benjamin D. Matthews, Akiko Mammoto et al. · Science | 24 Jun 2010 | 4,252 |
| 17 | A simple equation for description of solute release II. Fickian and anomalous release from swellable devices Philip L. Ritger, Nikolaos A. Peppas · Journal of Controlled Release | Jun 1987 | 4,060 |
| 18 | Tensional homeostasis and the malignant phenotype Matthew J. Paszek, Nastaran Zahir, Kandice R. Johnson et al. · Cancer Cell | Sep 2005 | 4,000 |
| 19 | Porous scaffold design for tissue engineering Scott J. Hollister · Nature Materials | Jul 2005 | 3,967 |
| 20 | Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing. James Carmichael, William DeGraff, Adi F. Gazdar et al. · PubMed | 15 Feb 1987 | 3,829 |
| 21 | Hydrogels in drug delivery: Progress and challenges Todd R. Hoare, Daniel S. Kohane · Polymer | 21 Jan 2008 | 3,776 |
| 22 | Polymers for 3D Printing and Customized Additive Manufacturing Samuel Clark Ligon, Robert Liska, Jürgen Stampfl et al. · Chemical Reviews | 30 Jul 2017 | 3,755 |
| 23 | Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling Stuart M. Chambers, Christopher A. Fasano, Eirini P. Papapetrou et al. · Nature Biotechnology | Mar 2009 | 3,745 |
| 24 | The ground state of embryonic stem cell self-renewal Qi‐Long Ying, Jason P. Wray, Jennifer Nichols et al. · Nature | May 2008 | 3,583 |
| 25 | Organoid Models and Applications in Biomedical Research Christodoulos Xinaris, Valerio Brizi, Giuseppe Remuzzi · The Nephron journals/Nephron journals | 2015 | 3,519 |
| 26 | Cell Movement Is Guided by the Rigidity of the Substrate Chun‐Min Lo, Hong-Bei Wang, Micah Dembo et al. · Biophysical Journal | Jul 2000 | 3,347 |
| 27 | 3D printing of polymer matrix composites: A review and prospective Xin Wang, Man Jiang, Zuowan Zhou et al. · Composites Part B Engineering | 16 Nov 2016 | 3,332 |
| 28 | Microfluidic organs-on-chips Sangeeta N. Bhatia, Donald E. Ingber · Nature Biotechnology | Aug 2014 | 3,302 |
| 29 | Synthesis, properties, and biomedical applications of gelatin methacryloyl (GelMA) hydrogels Kan Yue, Grissel Trujillo‐de Santiago, Mario Moisés Álvarez et al. · Biomaterials | 28 Aug 2015 | 3,152 |
| 30 | Cell locomotion and focal adhesions are regulated by substrate flexibility Robert J. Pelham, Yu‐li Wang · Proceedings of the National Academy of Sciences | 9 Dec 1997 | 3,063 |
| 31 | Mechanotransduction Across the Cell Surface and Through the Cytoskeleton Ning Wang, James P. Butler, Donald E. Ingber · Science | 21 May 1993 | 3,011 |
| 32 | Organogenesis in a dish: Modeling development and disease using organoid technologies Madeline A. Lancaster, Juergen A. Knoblich · Science | 17 Jul 2014 | 2,936 |
| 33 | Advances in engineering hydrogels Yu Shrike Zhang, Ali Khademhosseini · Science | 4 May 2017 | 2,896 |
| 34 | The third dimension bridges the gap between cell culture and live tissue Francesco Pampaloni, Emmanuel G. Reynaud, Ernst H. K. Stelzer · Nature Reviews Molecular Cell Biology | 8 Aug 2007 | 2,831 |
| 35 | Collective cell migration in morphogenesis, regeneration and cancer Peter Friedl, Darren T. Gilmour · Nature Reviews Molecular Cell Biology | 23 Jun 2009 | 2,826 |
| 36 | Third-Generation Biomedical Materials Larry L. Hench, Julia Margaret Polak · Science | 8 Feb 2002 | 2,794 |
| 37 | QUANTITATIVE STUDIES OF THE GROWTH OF MOUSE EMBRYO CELLS IN CULTURE AND THEIR DEVELOPMENT INTO ESTABLISHED LINES George J. Todaro, Howard Green · The Journal of Cell Biology | May 1963 | 2,773 |
| 38 | THE CHEMOTACTIC EFFECT OF MIXTURES OF ANTIBODY AND ANTIGEN ON POLYMORPHONUCLEAR LEUCOCYTES STEPHEN V. BOYDEN · The Journal of Experimental Medicine | Mar 1962 | 2,760 |
| 39 | Hydrogels as extracellular matrix mimics for 3D cell culture Mark W. Tibbitt, Kristi S. Anseth · Biotechnology and Bioengineering | 13 Apr 2009 | 2,743 |
| 40 | THE DEVELOPMENT OF FIBROBLAST COLONIES IN MONOLAYER CULTURES OF GUINEA‐PIG BONE MARROW AND SPLEEN CELLS A. J. Friedenstein, R. K. Chailakhjan, K. S. Lalykina · Cell Proliferation | Oct 1970 | 2,717 |
| 41 | Hydrogels in Regenerative Medicine Brandon V. Slaughter, Shahana S. Khurshid, Omar Z. Fisher et al. · Advanced Materials | 18 Jul 2009 | 2,690 |
| 42 | A 3D bioprinting system to produce human-scale tissue constructs with structural integrity Hyun‐Wook Kang, Sang Jin Lee, In Kap Ko et al. · Nature Biotechnology | 15 Feb 2016 | 2,642 |
| 43 | Solvent Compatibility of Poly(dimethylsiloxane)-Based Microfluidic Devices Jessamine Ng Lee, Cheolmin Park, George M. Whitesides · Analytical Chemistry | 11 Oct 2003 | 2,619 |
| 44 | Biomedical applications of hydrogels: A review of patents and commercial products Enrica Caló, Vitaliy V. Khutoryanskiy · European Polymer Journal | 29 Nov 2014 | 2,618 |
| 45 | Exploring and Engineering the Cell Surface Interface Molly M. Stevens, Julian H. George · Science | 18 Nov 2005 | 2,618 |
| 46 | Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors Rasheena Edmondson, Jessica Jenkins Broglie, Audrey F. Adcock et al. · Assay and Drug Development Technologies | May 2014 | 2,560 |
| 47 | Hydrogels with tunable stress relaxation regulate stem cell fate and activity Ovijit Chaudhuri, Luo Gu, Darinka D. Klumpers et al. · Nature Materials | 30 Nov 2015 | 2,484 |
| 48 | Poly(dimethylsiloxane) as a Material for Fabricating Microfluidic Devices J. Cooper McDonald, George M. Whitesides · Accounts of Chemical Research | 24 Apr 2002 | 2,453 |
| 49 | Cell-laden microengineered gelatin methacrylate hydrogels Jason William Nichol, Sandeep T. Koshy, Hojae Bae et al. · Biomaterials | 26 Apr 2010 | 2,399 |
| 50 | Tissue Engineering--Current Challenges and Expanding Opportunities Linda G. Griffith, Gail K. Naughton · Science | 8 Feb 2002 | 2,359 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.