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Most cited papers in Advanced Electron Microscopy Techniques and Applications

Advanced Electron Microscopy Techniques and Applications

What are the most cited papers in Advanced Electron Microscopy Techniques and Applications?

The most cited paper in Advanced Electron Microscopy Techniques and Applications is "LAMMPS - a flexible simulation tool for particle-based materials modeling at the atomic, meso, and continuum scales" (Aidan P. Thompson, Hasan Metin Aktulga, Richard A. Berger et al., 2021), with 12,569 citations. Next come "cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination" (11,217) and "Jalview Version 2—a multiple sequence alignment editor and analysis workbench" (11,179).

Showing 50 of 100 papers. Every paper with more than 1,046 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 LAMMPS - a flexible simulation tool for particle-based materials modeling at the atomic, meso, and continuum scales Aidan P. Thompson, Hasan Metin Aktulga, Richard A. Berger et al. · Computer Physics Communications Open access 22 Sep 2021 12,569
2 cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination Ali Punjani, John L. Rubinstein, David J. Fleet et al. · Nature Methods 6 Feb 2017 11,217
3 Jalview Version 2—a multiple sequence alignment editor and analysis workbench Andrew Mark Waterhouse, James B Procter, David M. A. Martin et al. · Bioinformatics Open access 16 Jan 2009 11,179
4 UCSF ChimeraX : Structure visualization for researchers, educators, and developers Eric F. Pettersen, Thomas D. Goddard, Conrad C. Huang et al. · Protein Science Open access 3 Sep 2020 10,674
5 MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy Shawn Q. Zheng, Eugene J. Palovcak, Jean‐Paul Armache et al. · Nature Methods Open access 27 Feb 2017 9,180
6 Imaging Intracellular Fluorescent Proteins at Nanometer Resolution Eric Betzig, George H. Patterson, Rachid Sougrat et al. · Science 10 Aug 2006 9,061
7 Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix Dorothee Claudia Liebschner et al. · Acta Crystallographica Section D Structural Biology Open access Oct 2019 7,679
8 ImageJ2: ImageJ for the next generation of scientific image data Curtis Rueden, Johannes Schindelin, Mark Hiner et al. · BMC Bioinformatics Open access 29 Nov 2017 6,379
9 Computer Visualization of Three-Dimensional Image Data Using IMOD James R. Kremer, David N. Mastronarde, J. Richard McIntosh · Journal of Structural Biology 1996 6,195
10 Automated electron microscope tomography using robust prediction of specimen movements David N. Mastronarde · Journal of Structural Biology 25 Aug 2005 6,180
11 RELION: Implementation of a Bayesian approach to cryo-EM structure determination Sjors H. W. Scheres · Journal of Structural Biology Open access 19 Sep 2012 6,175
12 CTFFIND4: Fast and accurate defocus estimation from electron micrographs Alexis L. Rohou, Nikolaus Grigorieff · Journal of Structural Biology Open access 13 Aug 2015 5,758
13 A guided tour into subcellular colocalization analysis in light microscopy Susanne Bolte, Fabrice P. Cordelières · Journal of Microscopy Dec 2006 5,686
14 Phase retrieval algorithms: a comparison James R. Fienup · Applied Optics Aug 1982 5,681
15 Gwyddion: an open-source software for SPM data analysis David Nečas, Petr Klapetek · Open Physics Open access 16 Nov 2011 4,514
16 Gctf: Real-time CTF determination and correction Kai Zhang · Journal of Structural Biology Open access 20 Nov 2015 4,155
17 Surpassing the lateral resolution limit by a factor of two using structured illumination microscopy Mats G. Gustafsson · Journal of Microscopy Open access May 2000 3,882
18 Real-space refinement in PHENIX for cryo-EM and crystallography Pavel V. Afonine, Billy K. Poon, Randy J. Read et al. · Acta Crystallographica Section D Structural Biology Open access 30 May 2018 3,869
19 Ultra-High Resolution Imaging by Fluorescence Photoactivation Localization Microscopy Samuel T. Hess, Thanu Prabha Kalambur Girirajan, Michael D. Mason · Biophysical Journal Open access 15 Sep 2006 3,705
20 Electron Energy-Loss Spectroscopy in the Electron Microscope Ray F. Egerton, Dale E. Newbury · Physics Today Nov 1987 3,431
21 Embedding in Epoxy Resins for Ultrathin Sectioning in Electron Microscopy Keith C. Richardson, Leonard Jarett, E. H. Finke · Stain Technology 1960 3,318
22 EMAN2: An extensible image processing suite for electron microscopy Guang Yi Tang, Liwei Peng, Philip Rupert Baldwin et al. · Journal of Structural Biology 11 Jun 2006 3,274
23 Far-Field Optical Nanoscopy Stefan W. Hell · Science 25 May 2007 3,002
24 iMOSFLM: a new graphical interface for diffraction-image processing withMOSFLM T. Geoff G. Battye, Luke Kontogiannis, Owen Johnson et al. · Acta Crystallographica Section D Biological Crystallography Open access 17 Mar 2011 2,958
25 Algebraic Reconstruction Techniques (ART) for three-dimensional electron microscopy and X-ray photography Richard Gordon, Robert Bender, Gábor T. Herman · Journal of Theoretical Biology Dec 1970 2,796
26 Optimal Determination of Particle Orientation, Absolute Hand, and Contrast Loss in Single-particle Electron Cryomicroscopy Peter B. Rosenthal, Richard A. Henderson · Journal of Molecular Biology Oct 2003 2,705
27 Trainable Weka Segmentation: a machine learning tool for microscopy pixel classification Ignacio Arganda‐Carreras, Verena Kaynig, Curtis Rueden et al. · Bioinformatics 28 Mar 2017 2,553
28 Ultrafast Spin Dynamics in Ferromagnetic Nickel Emmanuel Beaurepaire, J.‐C. Merle, A. Daunois et al. · Physical Review Letters 27 May 1996 2,463
29 EMAN: Semiautomated Software for High-Resolution Single-Particle Reconstructions Steven J. Ludtke, Philip Rupert Baldwin, Wah Keung Chiu · Journal of Structural Biology Dec 1999 2,442
30 Cryo-electron microscopy of vitrified specimens Jacques Dubochet, Marc Adrian, Jiin-Ju Chang et al. · Quarterly Reviews of Biophysics ReviewOpen access May 1988 2,424
31 Automated protein model building combined with iterative structure refinement. Anastassis Perrakis, Richard James Morris, Victor S. Lamzin · Nature Structural Biology May 1999 2,424
32 Maximally localized Wannier functions for entangled energy bands Ivo Souza, Nicola Marzari, David Vanderbilt · Physical review. B, Condensed matter Open access 19 Dec 2001 2,272
33 A collaborative framework for 3D alignment and classification of heterogeneous subvolumes in cryo-electron tomography Oleg Kuybeda, Gabriel A. Frank, Alberto Bartesaghi et al. · Journal of Structural Biology Open access 27 Oct 2012 2,247
34 Advanced methods of microscope control using μManager software Arthur Edelstein, Mark A. Tsuchida, Nenad Amodaj et al. · Journal of Biological Methods Open access 7 Nov 2014 2,234
35 Attosecond science P. B. Corkum, Ferenc Krausz · Nature Physics Jun 2007 2,150
36 Femtosecond X-ray protein nanocrystallography Henry N. Chapman et al. · Nature Open access Feb 2011 2,130
37 Accurate and efficient algorithm for Bader charge integration Min Yu, Dallas R. Trinkle · The Journal of Chemical Physics Open access 10 Feb 2011 2,108
38 Lattice light-sheet microscopy: Imaging molecules to embryos at high spatiotemporal resolution Bi‐Chang Chen et al. · Science Open access 23 Oct 2014 2,103
39 XtalView/Xfit—A Versatile Program for Manipulating Atomic Coordinates and Electron Density Duncan E. McRee · Journal of Structural Biology Apr 1999 2,102
40 Simultaneous phase and amplitude extraction from a single defocused image of a homogeneous object David M. Paganin, Sheridan C. Mayo, Timur E. Gureyev et al. · Journal of Microscopy Apr 2002 2,083
41 SPIDER and WEB: Processing and Visualization of Images in 3D Electron Microscopy and Related Fields Joachim Frank, Michael Radermacher, Pawel A. Penczek et al. · Journal of Structural Biology 1996 2,077
42 Quantifying the local resolution of cryo-EM density maps Alp Kucukelbir, Fred J. Sigworth, Hemant D. Tagare · Nature Methods Open access 10 Nov 2013 2,053
43 Automated molecular microscopy: The new Leginon system Christian J. M. Suloway, James Pulokas, Denis Fellmann et al. · Journal of Structural Biology 21 Apr 2005 2,048
44 Extending the methodology of X-ray crystallography to allow imaging of micrometre-sized non-crystalline specimens Jianwei Miao, Pambos S. Charalambous, Janos Kirz et al. · Nature Jul 1999 1,983
45 Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM Xueming Li, Paul E. Mooney, Shawn Q. Zheng et al. · Nature Methods Open access 3 May 2013 1,968
46 Non-uniform refinement: adaptive regularization improves single-particle cryo-EM reconstruction Ali Punjani, Haowei Zhang, David J. Fleet · Nature Methods 30 Nov 2020 1,940
47 7 × 7 Reconstruction on Si(111) Resolved in Real Space Gerd K. Binnig, Heinrich Rohrer, Ch. Gerber et al. · Physical Review Letters Open access 10 Jan 1983 1,904
48 Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs Tristan Bepler, Andrew Morin, Micah Rapp et al. · Nature Methods Open access 7 Oct 2019 1,871
49 Serial Block-Face Scanning Electron Microscopy to Reconstruct Three-Dimensional Tissue Nanostructure Winfried T. Denk, Heinz Horstmann · PLoS Biology Open access 14 Oct 2004 1,735
50 ThunderSTORM: a comprehensive ImageJ plug-in for PALM and STORM data analysis and super-resolution imaging Martin Ovesný, Pavel Křížek, Josef Borkovec et al. · Bioinformatics Open access 26 Apr 2014 1,704

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.