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Topic · Structural Biology

Advanced Electron Microscopy Techniques and Applications

Advanced Electron Microscopy Techniques and Applications is a research topic within Structural Biology. Science Explorer counts 22k research works in it since 1950. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers represents advancements in cryo-electron microscopy techniques, including single-particle analysis, electron tomography, and image processing for achieving atomic resolution. It covers topics such as beam-induced motion correction, high-resolution imaging of nanoparticles, and neural circuit reconstruction using advanced microscopy methods.

  • Cryo-Electron Microscopy
  • Single-Particle Analysis
  • Electron Tomography
  • Image Processing
  • Atomic Resolution
  • Structure Determination
  • Beam-Induced Motion Correction
  • High-Resolution Imaging
  • Nanoparticle Growth
  • Neural Circuit Reconstruction
Research works
22k
fractional, since 1950
In the world top 10%
2.1k
per year above
Top-10% rate
9.9%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+6%
the tick is no change
Largest producer
United States
37% of the 10 largest, 2022-now
Advanced Electron Microscopy Techniques and Applications

Which countries lead Advanced Electron Microscopy Techniques and Applications research?

By volume, the United States and China publish the most (1.2k and 566 works in 2022-now).

By volume, 2022-now

  1. 1 United States 1.2k works
  2. 2 China 566 works
  3. 3 Germany 465 works
  4. 4 Japan 287 works
  5. 5 United Kingdom 249 works
  6. 6 France 193 works
  7. 7 South Korea 94 works
  8. 8 Netherlands 90 works
  9. 9 Switzerland 87 works
  10. 10 Russia 86 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 36.5%China: 17.0%Germany: 14.0%Japan: 8.6%6 others listed: 24.0%37%largest
United States1,217 · 36.5%China566 · 17.0%Germany465 · 14.0%Japan287 · 8.6%6 others listed799 · 24.0%

Shares of the rows listed above, not of the whole node.

Which institutions lead Advanced Electron Microscopy Techniques and Applications research?

By volume in 2022-now, Centre National de la Recherche Scientifique publishes the most Advanced Electron Microscopy Techniques and Applications research, followed by Chinese Academy of Sciences and Helmholtz Association of German Research Centres.

By volume, 2022-now

  1. 1 Centre National de la Recherche ScientifiqueFrance 101 works
  2. 2 Chinese Academy of SciencesChina 86 works
  3. 3 Helmholtz Association of German Research CentresGermany 65 works
  4. 4 Max Planck SocietyGermany 62 works
  5. 5 Stanford UniversityUnited States 49 works
  6. 6 Lawrence Berkeley National LaboratoryUnited States 37 works
  7. 7 Russian Academy of SciencesRussia 31 works
  8. 8 Cornell UniversityUnited States 29 works
  9. 9 University of California, BerkeleyUnited States 28 works
  10. 10 Oak Ridge National LaboratoryUnited States 28 works

Who are the leading researchers in Advanced Electron Microscopy Techniques and Applications?

The most-cited researchers publishing on Advanced Electron Microscopy Techniques and Applications include Zhong Lin Wang, Georg Kresse and Kostya S. Novoselov.

  1. 1 Zhong Lin Wang United States 491k citations
  2. 2 Georg Kresse Austria 431k citations
  3. 3 Kostya S. Novoselov United Kingdom 331k citations
  4. 4 Yury G. Gogotsi United States 313k citations
  5. 5 Matthias Mann Germany 308k citations
  6. 6 Luigi Ferrucci United States 281k citations
  7. 7 Yi Ping Cui United States 261k citations
  8. 8 Ben Zhong Tang China 261k citations
  9. 9 Xiaogang Wang China 260k citations
  10. 10 Omar M. Yaghi United States 254k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Advanced Electron Microscopy Techniques and Applications?

The most cited paper in Advanced Electron Microscopy Techniques and Applications is "LAMMPS - a flexible simulation tool for particle-based materials modeling at the atomic, meso, and continuum scales" (Aidan P. Thompson, Hasan Metin Aktulga, Richard A. Berger et al., 2021), with 12,569 citations. Next come "cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination" (11,217) and "Jalview Version 2—a multiple sequence alignment editor and analysis workbench" (11,179).

Most cited papers
#PaperReleasedCitations
1 LAMMPS - a flexible simulation tool for particle-based materials modeling at the atomic, meso, and continuum scales Aidan P. Thompson, Hasan Metin Aktulga, Richard A. Berger et al. · Computer Physics Communications Open access 22 Sep 2021 12,569
2 cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination Ali Punjani, John L. Rubinstein, David J. Fleet et al. · Nature Methods 6 Feb 2017 11,217
3 Jalview Version 2—a multiple sequence alignment editor and analysis workbench Andrew Mark Waterhouse, James B Procter, David M. A. Martin et al. · Bioinformatics Open access 16 Jan 2009 11,179
4 UCSF ChimeraX : Structure visualization for researchers, educators, and developers Eric F. Pettersen, Thomas D. Goddard, Conrad C. Huang et al. · Protein Science Open access 3 Sep 2020 10,674
5 MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy Shawn Q. Zheng, Eugene J. Palovcak, Jean‐Paul Armache et al. · Nature Methods Open access 27 Feb 2017 9,180
All 100 most cited papers, with filters and sorting

Where is Advanced Electron Microscopy Techniques and Applications research done?

The largest centres of Advanced Electron Microscopy Techniques and Applications research in 2022-now are Beijing (China), Tokyo (Japan), Paris (France) and Berkeley (United States). Among places with at least 20 works in it, it is an unusually large share of all research in Didcot, Upton and Menlo Park.

Largest cities, 2022-now

  1. 1 BeijingChina 174 works
  2. 2 TokyoJapan 84 works
  3. 3 ParisFrance 69 works
  4. 4 BerkeleyUnited States 65 works
  5. 5 ShanghaiChina 57 works
  6. 6 LondonUnited Kingdom 51 works
  7. 7 HamburgGermany 50 works
  8. 8 New YorkUnited States 48 works
  9. 9 MoscowRussia 44 works
  10. 10 BerlinGermany 38 works

Where it is the local speciality

  1. DidcotGB · 22.3 works68×
  2. UptonUS · 22.8 works59×
  3. Menlo ParkUS · 26.2 works43×
  4. LemontUS · 28.1 works38×
  5. JülichDE · 22.8 works23×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Advanced Electron Microscopy Techniques and Applications than the world average.

See Advanced Electron Microscopy Techniques and Applications on the map

Where is the best place to study Advanced Electron Microscopy Techniques and Applications?

Among universities, judged by research, Massachusetts Institute of Technology, Stanford University and Peking University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%mean 15.76%fractional works in this field (log) →share of work in the world top 10% →Massachusetts Instit…Peking UniversityUniversity of Califo…Stanford University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Massachusetts Institute of TechnologyUnited States 81.420.9%9.3×23 +21.8%
2Stanford UniversityUnited States 74.312.7%9.4×49 -14.5%
3Peking UniversityChina 70.720.2%3.7×27 +81.8%
4University of California, BerkeleyUnited States 70.013.2%8.4×28 +7.7%
5Cornell UniversityUnited States 65.413.8%6.1×28 +11.7%
6Yale UniversityUnited States 62.318.1%3.8×15 +29.5%
7École Polytechnique Fédérale de LausanneSwitzerland 61.114.7%12.1×18 -16.6%
8University of OxfordUnited Kingdom 60.611.4%4.8×24 -2.8%
9Max Planck Institute for Multidisciplinary Sciences 60.520.0%133.7×8 -
10Universität HamburgGermany 59.012.6%6.8×18 +40.4%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Advanced Electron Microscopy Techniques and Applications, country by country

Is Advanced Electron Microscopy Techniques and Applications research growing?

Output in 2022-2025 was 6% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Advanced Electron Microscopy Techniques and Applications.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Advanced Electron Microscopy Techniques and Applications as a percentage of every work published that year, 0.015% in 2024.

still counting0.010%0.020%0.030%Advanced Electron Microscopy Techniques and Applications0.016% in 202519801990200020102020

Fractional works of Advanced Electron Microscopy Techniques and Applications over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Advanced Electron Microscopy Techniques and Applications9.7% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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