Most cited papers in Advanced Fluorescence Microscopy Techniques
What are the most cited papers in Advanced Fluorescence Microscopy Techniques?
The most cited paper in Advanced Fluorescence Microscopy Techniques is "Comprehensive Integration of Single-Cell Data" (Tim Stuart, Andrew W. Butler, Paul Hoffman et al., 2019), with 17,471 citations. Next come "Fast, sensitive and accurate integration of single-cell data with Harmony" (11,339) and "Two-Photon Laser Scanning Fluorescence Microscopy" (9,531).
Showing 50 of 100 papers. Every paper with more than 1,560 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Comprehensive Integration of Single-Cell Data Tim Stuart, Andrew W. Butler, Paul Hoffman et al. · Cell | Jun 2019 | 17,471 |
| 2 | Fast, sensitive and accurate integration of single-cell data with Harmony Ilya Korsunsky, Nghia Millard, Jean Fan et al. · Nature Methods | 18 Nov 2019 | 11,339 |
| 3 | Two-Photon Laser Scanning Fluorescence Microscopy Winfried T. Denk, James H. Strickler, Watt W. Webb · Science | 6 Apr 1990 | 9,531 |
| 4 | Imaging Intracellular Fluorescent Proteins at Nanometer Resolution Eric Betzig, George H. Patterson, Rachid Sougrat et al. · Science | 10 Aug 2006 | 9,061 |
| 5 | Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM) Michael J. Rust, Mark Bates, Xiaowei Zhuang · Nature Methods | 9 Aug 2006 | 8,412 |
| 6 | THE GREEN FLUORESCENT PROTEIN Roger Y. Tsien · Annual Review of Biochemistry | Jun 1998 | 6,213 |
| 7 | Breaking the diffraction resolution limit by stimulated emission: stimulated-emission-depletion fluorescence microscopy Stefan W. Hell, Jan Wichmann · Optics Letters | Jun 1994 | 6,210 |
| 8 | Emergence of simple-cell receptive field properties by learning a sparse code for natural images Bruno A. Olshausen, David J. Field · Nature | Jun 1996 | 5,901 |
| 9 | A guided tour into subcellular colocalization analysis in light microscopy Susanne Bolte, Fabrice P. Cordelières · Journal of Microscopy | Dec 2006 | 5,686 |
| 10 | Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein Nathan C. Shaner, Robert E. Campbell, Paul A. Steinbach et al. · Nature Biotechnology | 21 Nov 2004 | 4,783 |
| 11 | Measurement of subpicosecond time intervals between two photons by interference C. K. Hong, Z. Y. Ou, L. Mandeļ · Physical Review Letters | 2 Nov 1987 | 4,415 |
| 12 | Deep tissue two-photon microscopy Fritjof Helmchen, Winfried T. Denk · Nature Methods | 18 Nov 2005 | 4,229 |
| 13 | Nonlinear magic: multiphoton microscopy in the biosciences Warren R. Zipfel, Rebecca M. Williams, Watt W. Webb · Nature Biotechnology | 31 Oct 2003 | 3,908 |
| 14 | TrackMate: An open and extensible platform for single-particle tracking Jean-Yves Tinévez, Nick Perry, Johannes Schindelin et al. · Methods | 7 Oct 2016 | 3,890 |
| 15 | Surpassing the lateral resolution limit by a factor of two using structured illumination microscopy Mats G. Gustafsson · Journal of Microscopy | May 2000 | 3,882 |
| 16 | Sparse coding with an overcomplete basis set: A strategy employed by V1? Bruno A. Olshausen, David J. Field · Vision Research | Dec 1997 | 3,757 |
| 17 | A global double‐fluorescent Cre reporter mouse Mandar Deepak Muzumdar, Bosiljka Tasic, Kazunari Miyamichi et al. · genesis | Sep 2007 | 3,753 |
| 18 | Ultra-High Resolution Imaging by Fluorescence Photoactivation Localization Microscopy Samuel T. Hess, Thanu Prabha Kalambur Girirajan, Michael D. Mason · Biophysical Journal | 15 Sep 2006 | 3,705 |
| 19 | Single-pixel imaging via compressive sampling Marco F. Duarte, Mark A. Davenport, Dharmpal Takhar et al. · IEEE Signal Processing Magazine | Mar 2008 | 3,637 |
| 20 | Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin Atsushi Miyawaki, Juan Llopis, Roger Heim et al. · Nature | 28 Aug 1997 | 3,272 |
| 21 | Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus Shankar Srinivas, Tomoko Watanabe, Chyuan‐Sheng Lin et al. · BMC Developmental Biology | 27 Mar 2001 | 3,258 |
| 22 | Spatially resolved, highly multiplexed RNA profiling in single cells Kok Hao Chen, Alistair Nicol Boettiger, Jeffrey R. Moffitt et al. · Science | 9 Apr 2015 | 3,242 |
| 23 | Imaging Neuronal Subsets in Transgenic Mice Expressing Multiple Spectral Variants of GFP Guoping Feng, Rebecca H. Mellor, Michael B. Bernstein et al. · Neuron | Oct 2000 | 3,168 |
| 24 | Far-Field Optical Nanoscopy Stefan W. Hell · Science | 25 May 2007 | 3,002 |
| 25 | Three-Dimensional Super-Resolution Imaging by Stochastic Optical Reconstruction Microscopy Bo Han Huang, Wen-Qin Wang, Mark Bates et al. · Science | 3 Jan 2008 | 2,942 |
| 26 | A guide to choosing fluorescent proteins Nathan C. Shaner, Paul A. Steinbach, Roger Y. Tsien · Nature Methods | 18 Nov 2005 | 2,880 |
| 27 | Finer features for functional microdevices Satoshi Kawata, Hong‐Bo Sun, Tomokazu A. Tanaka et al. · Nature | Aug 2001 | 2,863 |
| 28 | A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications Takeharu Nagai, Keiji Ibata, Eun Sun Park et al. · Nature Biotechnology | 2002 | 2,815 |
| 29 | The Fluorescent Toolbox for Assessing Protein Location and Function Ben N. G. Giepmans, Stephen Adams, Mark H. Ellisman et al. · Science | 13 Apr 2006 | 2,784 |
| 30 | FACS-optimized mutants of the green fluorescent protein (GFP) Brendan P. Cormack, Raphael H. Valdivia, Stanley Falkow · Gene | 1996 | 2,696 |
| 31 | The contrast sensitivity of retinal ganglion cells of the cat Christina Enroth‐Cugell, J. G. Robson · The Journal of Physiology | Dec 1966 | 2,664 |
| 32 | Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins Gero Miesenböck, Dino A. De Angelis, James Edward Rothman · Nature | Jul 1998 | 2,661 |
| 33 | Improvements to the APBS biomolecular solvation software suite Elizabeth R. Jurrus et al. · Protein Science | 24 Aug 2017 | 2,626 |
| 34 | ‘Green mice’ as a source of ubiquitous green cells Masaru Okabe, Masahito Ikawa, Katsuya Kominami et al. · FEBS Letters | 5 May 1997 | 2,620 |
| 35 | Engineering and characterization of a superfolder green fluorescent protein J.D. Pédelacq, Stéphanie Cabantous, Timothy H. Tran et al. · Nature Biotechnology | 20 Dec 2005 | 2,497 |
| 36 | Optical Sectioning Deep Inside Live Embryos by Selective Plane Illumination Microscopy Jan Huisken, Jim Swoger, Filippo Del Bene et al. · Science | 13 Aug 2004 | 2,468 |
| 37 | Efficient sparse coding algorithms Honglak Lee, Alexis Battle, Rajat Raina et al. · The MIT Press eBooks | 7 Sep 2007 | 2,410 |
| 38 | Chromosome territories, nuclear architecture and gene regulation in mammalian cells Thomas John Cremer, Christoph G. Cremer · Nature Reviews Genetics | Apr 2001 | 2,407 |
| 39 | A monomeric red fluorescent protein Robert E. Campbell, Oded Tour, Amy E. Palmer et al. · Proceedings of the National Academy of Sciences | 11 Jun 2002 | 2,402 |
| 40 | Precise Nanometer Localization Analysis for Individual Fluorescent Probes Russell E. Thompson, Daniel R. Larson, Watt W. Webb · Biophysical Journal | May 2002 | 2,369 |
| 41 | Imaging in the era of molecular oncology Ralph Weissleder, Mikaël J. Pittet · Nature | 2 Apr 2008 | 2,364 |
| 42 | Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression Asako Sakaue-Sawano, Hiroshi Kurokawa, Toshifumi Morimura et al. · Cell | Feb 2008 | 2,347 |
| 43 | Lifeact: a versatile marker to visualize F-actin Julia Riedl, Álvaro H. Crevenna, Kai Kessenbrock et al. · Nature Methods | 8 Jun 2008 | 2,319 |
| 44 | CellProfiler 4: improvements in speed, utility and usability David R. Stirling, Madison J. Swain-Bowden, Alice M. Lucas et al. · BMC Bioinformatics | 10 Sep 2021 | 2,303 |
| 45 | Water-Soluble Quantum Dots for Multiphoton Fluorescence Imaging in Vivo Daniel R. Larson, Warren R. Zipfel, Rebecca M. Williams et al. · Science | 29 May 2003 | 2,286 |
| 46 | Label-Free Biomedical Imaging with High Sensitivity by Stimulated Raman Scattering Microscopy Christian W. Freudiger, Wei Min, Brian G. Saar et al. · Science | 18 Dec 2008 | 2,275 |
| 47 | Nonlinear structured-illumination microscopy: Wide-field fluorescence imaging with theoretically unlimited resolution Mats G. Gustafsson · Proceedings of the National Academy of Sciences | 2 Sep 2005 | 2,261 |
| 48 | Crystal Structure of the Aequorea victoria Green Fluorescent Protein Mats Ormö, Andrew B. Cubitt, Karen Kallio et al. · Science | 6 Sep 1996 | 2,245 |
| 49 | Measurement of co‐localization of objects in dual‐colour confocal images Erik M. M. Manders, Fons J. Verbeek, Jacob A. Aten · Journal of Microscopy | Mar 1993 | 2,241 |
| 50 | Advanced methods of microscope control using μManager software Arthur Edelstein, Mark A. Tsuchida, Nenad Amodaj et al. · Journal of Biological Methods | 7 Nov 2014 | 2,234 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.