Most cited papers in Advanced Proteomics Techniques and Applications
What are the most cited papers in Advanced Proteomics Techniques and Applications?
The most cited paper in Advanced Proteomics Techniques and Applications is "DISC ELECTROPHORESIS – II METHOD AND APPLICATION TO HUMAN SERUM PROTEINS*" (Baruch J. Davis, 1964), with 18,971 citations. Next come "Tissue-based map of the human proteome" (16,343) and "MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification" (15,998).
Showing 50 of 100 papers. Every paper with more than 2,540 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | DISC ELECTROPHORESIS – II METHOD AND APPLICATION TO HUMAN SERUM PROTEINS* Baruch J. Davis · Annals of the New York Academy of Sciences | Dec 1964 | 18,971 |
| 2 | Tissue-based map of the human proteome Mathias Uhlén et al. · Science | 22 Jan 2015 | 16,343 |
| 3 | MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification Jürgen Cox, Matthias Mann · Nature Biotechnology | 23 Nov 2008 | 15,998 |
| 4 | TBtools: An Integrative Toolkit Developed for Interactive Analyses of Big Biological Data Chengjie Chen, Hao Chen, Yi Zhang et al. · Molecular Plant | 23 Jun 2020 | 15,674 |
| 5 | The Perseus computational platform for comprehensive analysis of (prote)omics data Stefka Tyanova, Tikira Temu, Pavel G. Sinitcyn et al. · Nature Methods | 27 Jun 2016 | 9,121 |
| 6 | Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels Andrej Shevchenko, Matthias S. Wilm, Ole Vorm et al. · Analytical Chemistry | Mar 1996 | 9,120 |
| 7 | Protein Identification and Analysis Tools on the ExPASy Server Elisabeth Gasteiger, Christine Hoogland, Alexandre Gattiker et al. · Humana Press eBooks | 2005 | 8,916 |
| 8 | Universal sample preparation method for proteome analysis Jacek R. Wiśniewski, Alexandre Zougman, Nagarjuna Nagaraj et al. · Nature Methods | 19 Apr 2009 | 8,878 |
| 9 | The STRING database in 2021: customizable protein–protein networks, and functional characterization of user-uploaded gene/measurement sets Damian Szklarczyk, Annika L Gable, Katerina C. Nastou et al. · Nucleic Acids Research | 23 Nov 2020 | 8,805 |
| 10 | “Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A W. Neal Burnette · Analytical Biochemistry | Apr 1981 | 8,516 |
| 11 | Probability-based protein identification by searching sequence databases using mass spectrometry data David N. Perkins, Darryl Pappin, David M. Creasy et al. · Electrophoresis | Dec 1999 | 8,335 |
| 12 | Pfam: The protein families database in 2021 Jaina Mistry, Sara Chuguransky, Lowri Williams et al. · Nucleic Acids Research | 6 Oct 2020 | 8,165 |
| 13 | UniProt: the Universal Protein knowledgebase Rolf Apweiler · Nucleic Acids Research | 17 Dec 2003 | 7,889 |
| 14 | The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible Damian Szklarczyk, John H. Morris, Helen Victoria Cook et al. · Nucleic Acids Research | 11 Oct 2016 | 7,527 |
| 15 | The PRIDE database and related tools and resources in 2019: improving support for quantification data Yasset Pérez‐Riverol et al. · Nucleic Acids Research | 22 Oct 2018 | 7,481 |
| 16 | The rapid generation of mutation data matrices from protein sequences David T. Jones, William Ramsay Taylor, Janet M. Thornton · Computer applications in the biosciences | 1992 | 7,214 |
| 17 | Mass spectrometry-based proteomics Ruedi Aebersold, Matthias Mann · Nature | Mar 2003 | 6,961 |
| 18 | The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences Yasset Pérez‐Riverol, Jingwen Bai, Chakradhar Bandla et al. · Nucleic Acids Research | 15 Oct 2021 | 6,874 |
| 19 | Sparse inverse covariance estimation with the graphical lasso Jerome H. Friedman, Trevor Hastie, Robert Tibshirani · Biostatistics | 12 Dec 2007 | 6,735 |
| 20 | An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database Jimmy K. Eng, Ashley L. McCormack, John R. Yates · Journal of the American Society for Mass Spectrometry | Nov 1994 | 6,681 |
| 21 | Pfam: the protein families database ROBERT FINN, Alex Bateman, Jody Clements et al. · Nucleic Acids Research | 27 Nov 2013 | 6,604 |
| 22 | The Pfam protein families database: towards a more sustainable future ROBERT FINN, Penelope C. Coggill, Ruth Y. Eberhardt et al. · Nucleic Acids Research | 15 Dec 2015 | 6,569 |
| 23 | HMMER web server: interactive sequence similarity searching ROBERT FINN, Jody Clements, Sean R. Eddy · Nucleic Acids Research | 18 May 2011 | 6,555 |
| 24 | A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples Mary Ann K. Markwell, Suzanne M. Haas, LORAN L. BIEBER et al. · Analytical Biochemistry | Jun 1978 | 6,504 |
| 25 | Amino acid substitution matrices from protein blocks. Steven Henikoff, Jorja G. Henikoff · Proceedings of the National Academy of Sciences | 15 Nov 1992 | 6,493 |
| 26 | Primer-BLAST: A tool to design target-specific primers for polymerase chain reaction Jian Ye, George Coulouris, Irena Zaretskaya et al. · BMC Bioinformatics | 18 Jun 2012 | 6,397 |
| 27 | Protein Identification and Analysis Tools in the ExPASy Server Marc Ronald Wilkins, Elisabeth Gasteiger, Amos Bairoch et al. · Humana Press eBooks | 14 Nov 2003 | 6,262 |
| 28 | Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment Jürgen Cox, Nadin Neuhauser, Annette Michalski et al. · Journal of Proteome Research | 21 Jan 2011 | 5,975 |
| 29 | ExPASy: the proteomics server for in-depth protein knowledge and analysis Elisabeth Gasteiger · Nucleic Acids Research | 24 Jun 2003 | 5,809 |
| 30 | Stable Isotope Labeling by Amino Acids in Cell Culture, SILAC, as a Simple and Accurate Approach to Expression Proteomics Shao‐En Ong, Blagoy Blagoev, Irina Kratchmarova et al. · Molecular & Cellular Proteomics | May 2002 | 5,654 |
| 31 | Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ Jürgen Cox, Marco Y. Hein, Christian A. Luber et al. · Molecular & Cellular Proteomics | 18 Jun 2014 | 5,646 |
| 32 | The MaxQuant computational platform for mass spectrometry-based shotgun proteomics Stefka Tyanova, Tikira Temu, Jüergen Cox · Nature Protocols | 27 Oct 2016 | 5,351 |
| 33 | The Pfam protein families database in 2019 Sara El-Gebali, Jaina Mistry, Alex Bateman et al. · Nucleic Acids Research | 9 Oct 2018 | 5,256 |
| 34 | In-gel digestion for mass spectrometric characterization of proteins and proteomes Andrej Shevchenko, Henrik Tomas, J. Havli et al. · Nature Protocols | Dec 2006 | 5,186 |
| 35 | Skyline: an open source document editor for creating and analyzing targeted proteomics experiments Brendan MacLean, Daniela M. Tomazela, Nicholas Shulman et al. · Bioinformatics | 9 Feb 2010 | 5,063 |
| 36 | MAFFT version 5: improvement in accuracy of multiple sequence alignment Kazutaka Katoh · Nucleic Acids Research | 19 Jan 2005 | 5,033 |
| 37 | A Statistical Model for Identifying Proteins by Tandem Mass Spectrometry Alexey I. Nesvizhskii, Andrew Keller, Eugene Kolker et al. · Analytical Chemistry | 15 Jul 2003 | 5,023 |
| 38 | Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips Juri Rappsilber, Matthias Mann, Yasushi Ishihama · Nature Protocols | Aug 2007 | 5,019 |
| 39 | Empirical Statistical Model To Estimate the Accuracy of Peptide Identifications Made by MS/MS and Database Search Andrew Keller, Alexey I. Nesvizhskii, Eugene Kolker et al. · Analytical Chemistry | 12 Sep 2002 | 5,013 |
| 40 | Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes. Paul Thomas Matsudaira · Journal of Biological Chemistry | Jul 1987 | 4,982 |
| 41 | Functional organization of the yeast proteome by systematic analysis of protein complexes Anne‐Claude Gavin et al. · Nature | 2002 | 4,816 |
| 42 | Large-scale analysis of the yeast proteome by multidimensional protein identification technology Michael P. Washburn, Dirk Andreas Wolters, John R. Yates · Nature Biotechnology | Mar 2001 | 4,806 |
| 43 | Quantitative analysis of complex protein mixtures using isotope-coded affinity tags Steven P. Gygi, Beate Rist, Scott A. Gerber et al. · Nature Biotechnology | Oct 1999 | 4,680 |
| 44 | Multiplexed Protein Quantitation in Saccharomyces cerevisiae Using Amine-reactive Isobaric Tagging Reagents Philip L. Ross, Yulin Huang, Jason Marchese et al. · Molecular & Cellular Proteomics | 22 Sep 2004 | 4,464 |
| 45 | A cross-platform toolkit for mass spectrometry and proteomics Matthew Chambers et al. · Nature Biotechnology | Oct 2012 | 4,457 |
| 46 | The Human Plasma Proteome N. Leigh Anderson, Norman G. Anderson, Norman G. Anderson et al. · Molecular & Cellular Proteomics | Nov 2002 | 4,430 |
| 47 | Insights into the regulation of protein abundance from proteomic and transcriptomic analyses Christine Vogel, Edward M. Marcotte · Nature Reviews Genetics | 13 Mar 2012 | 4,352 |
| 48 | Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry Joshua Eric Elias, Steven P. Gygi · Nature Methods | 27 Feb 2007 | 4,142 |
| 49 | Silver stain for proteins in polyacrylamide gels: A modified procedure with enhanced uniform sensitivity James H. Morrissey · Analytical Biochemistry | Nov 1981 | 4,100 |
| 50 | MZmine 2: Modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data Tomáš Pluskal, Sandra D. Castillo, Alejandro Villar‐Briones et al. · BMC Bioinformatics | 23 Jul 2010 | 4,019 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.