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Most cited papers in AI in cancer detection

What are the most cited papers in AI in cancer detection?

The most cited paper in AI in cancer detection is "A survey on deep learning in medical image analysis" (Geert J. S. Litjens, Thijs Kooi, Babak Ehteshami Bejnordi et al., 2017), with 15,309 citations. Next come "pROC: an open-source package for R and S+ to analyze and compare ROC curves" (14,550) and "Dermatologist-level classification of skin cancer with deep neural networks" (14,423).

Showing 50 of 100 papers. Every paper with more than 1,113 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 A survey on deep learning in medical image analysis Geert J. S. Litjens, Thijs Kooi, Babak Ehteshami Bejnordi et al. · Medical Image Analysis Open access 26 Jul 2017 15,309
2 pROC: an open-source package for R and S+ to analyze and compare ROC curves Xavier Robin, Natacha Turck, Alexandre Hainard et al. · BMC Bioinformatics Open access 17 Mar 2011 14,550
3 Dermatologist-level classification of skin cancer with deep neural networks Andre Esteva, Brett Kuprel, Roberto A. Novoa et al. · Nature Open access 25 Jan 2017 14,423
4 A survey on Image Data Augmentation for Deep Learning Connor Shorten, Taghi M. Khoshgoftaar · Journal Of Big Data Open access 6 Jul 2019 13,152
5 QuPath: Open source software for digital pathology image analysis Peter Bankhead, Maurice Bernard Loughrey, José A. Fernández et al. · Scientific Reports Open access 28 Nov 2017 9,140
6 Radiomics: Images Are More than Pictures, They Are Data Robert J. Gillies, Paul E. Kinahan, Hedvig Hricak · Radiology Open access 18 Nov 2015 8,616
7 Unified segmentation John Ashburner, Karl John Friston · NeuroImage 2 Apr 2005 7,633
8 The Multimodal Brain Tumor Image Segmentation Benchmark (BRATS) Bjoern H. Menze et al. · IEEE Transactions on Medical Imaging Open access 4 Dec 2014 6,843
9 Radiomics: Extracting more information from medical images using advanced feature analysis Philippe Lambin, Emmanuel Rios-Velazquez, Ralph T. H. Leijenaar et al. · European Journal of Cancer Open access 16 Jan 2012 6,202
10 Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes Joel S. Parker, Michael Eugene Mullins, Maggie C.U. Cheang et al. · Journal of Clinical Oncology Open access 9 Feb 2009 4,974
11 Deep Learning in Medical Image Analysis Dinggang G. Shen, Guorong Wu, Heung‐Il Suk · Annual Review of Biomedical Engineering ReviewOpen access 16 Mar 2017 4,947
12 Convolutional neural networks: an overview and application in radiology Rikiya Yamashita, Mizuho Nishio, Richard Kinh Gian et al. · Insights into Imaging Open access 22 Jun 2018 4,717
13 Convolutional networks for images, speech, and time series Yann LeCun, Yoshua Bengio · HAL (Le Centre pour la Communication Scientifique Directe) Book chapter Oct 1998 4,363
14 Medical image analysis: progress over two decades and the challenges ahead James S. Duncan, Nicholas Ayache · IEEE Transactions on Pattern Analysis and Machine Intelligence Open access 2000 4,166
15 The Image Biomarker Standardization Initiative: Standardized Quantitative Radiomics for High-Throughput Image-based Phenotyping Alex Zwanenburg et al. · Radiology Open access 10 Mar 2020 4,159
16 Artificial intelligence in radiology Ahmed Hosny, Chintan Parmar, John Quackenbush et al. · Nature reviews. Cancer ReviewOpen access 17 May 2018 3,801
17 ilastik: interactive machine learning for (bio)image analysis Stuart Berg, Dominik Kutra, Thorben Kroeger et al. · Nature Methods Open access 30 Sep 2019 3,760
18 How To Build and Interpret a Nomogram for Cancer Prognosis Alexia E. Iasonos, Deborah Schrag, Ganesh V. Raj et al. · Journal of Clinical Oncology 6 Mar 2008 3,461
19 Machine learning applications in cancer prognosis and prediction Konstantina D. Kourou, Themis P. Exarchos, Konstantinos Exarchos et al. · Computational and Structural Biotechnology Journal Open access 15 Nov 2014 3,415
20 Diagnostic Assessment of Deep Learning Algorithms for Detection of Lymph Node Metastases in Women With Breast Cancer Babak Ehteshami Bejnordi et al. · JAMA Open access 12 Dec 2017 3,405
21 International evaluation of an AI system for breast cancer screening Scott Mayer McKinney et al. · Nature Open access 2020 3,314
22 Convolutional Neural Networks for Medical Image Analysis: Full Training or Fine Tuning? Nima Tajbakhsh, Jae Y. Shin, Suryakanth Gurudu et al. · IEEE Transactions on Medical Imaging Open access 7 Mar 2016 3,309
23 beta-VAE: Learning Basic Visual Concepts with a Constrained Variational Framework Irina Higgins, Löıc Matthey, Arka Pal et al. · International Conference on Learning Representations Conference paper 24 Apr 2017 3,076
24 Classification and mutation prediction from non–small cell lung cancer histopathology images using deep learning Nicolas Coudray, Paolo Ocampo, Theodore Sakellaropoulos et al. · Nature Medicine Open access 6 Sep 2018 3,013
25 Clinical-grade computational pathology using weakly supervised deep learning on whole slide images Gabriele S. V. Campanella, Matthew G. Hanna, Luke Geneslaw et al. · Nature Medicine Open access 15 Jul 2019 2,845
26 Segment anything in medical images Jun Ma, Yuting He, Feifei Li et al. · Nature Communications Open access 22 Jan 2024 2,830
27 Automated detection of COVID-19 cases using deep neural networks with X-ray images Tülin Öztürk, Muhammed Talo, Eylul Azra Yildirim et al. · Computers in Biology and Medicine Open access 28 Apr 2020 2,702
28 Laser Capture Microdissection Michael R. Emmert‐Buck, Robert F. Bonner, Paul David Smith et al. · Science 8 Nov 1996 2,575
29 H-DenseUNet: Hybrid Densely Connected UNet for Liver and Tumor Segmentation From CT Volumes Xiaomeng Li, Hao Chen, Xiaojuan Qi et al. · IEEE Transactions on Medical Imaging 11 Jun 2018 2,526
30 Mammographic Density and the Risk and Detection of Breast Cancer Norman F. Boyd, Helen Guo, Lisa Joy Martin et al. · New England Journal of Medicine Open access 17 Jan 2007 2,510
31 Support vector machine classification and validation of cancer tissue samples using microarray expression data Terrence S. Furey, Nello Cristianini, Nigel Duffy et al. · Bioinformatics Open access Oct 2000 2,475
32 Covid-19: automatic detection from X-ray images utilizing transfer learning with convolutional neural networks Ioannis D. Apostolopoulos, Tzani A. Mpesiana · Physical and Engineering Sciences in Medicine Open access 3 Apr 2020 2,435
33 MultiResUNet : Rethinking the U-Net architecture for multimodal biomedical image segmentation Nabil Ibtehaz, M. Sohel Rahman · Neural Networks Open access 4 Sep 2019 2,356
34 Current Methods in Medical Image Segmentation Dzung L. Pham, Chenyang Xu, Jerry L. Prince · Annual Review of Biomedical Engineering Review Aug 2000 2,349
35 Opportunities and obstacles for deep learning in biology and medicine Travers H. Ching et al. · Journal of The Royal Society Interface Open access Apr 2018 2,322
36 The practical implementation of artificial intelligence technologies in medicine Jianxing He, Sally L. Baxter, Jie Xu et al. · Nature Medicine Open access 24 Dec 2018 2,319
37 CE-Net: Context Encoder Network for 2D Medical Image Segmentation Zaiwang Gu, Jun Cheng, Huazhu Fu et al. · IEEE Transactions on Medical Imaging Open access 7 Mar 2019 2,282
38 Simultaneous Truth and Performance Level Estimation (STAPLE): An Algorithm for the Validation of Image Segmentation Simon Keith Warfield, Kelly H. Zou, William M. Wells · IEEE Transactions on Medical Imaging Open access Jul 2004 2,100
39 Histopathological Image Analysis: A Review Metin N. Gürcan, Laura E. Boucheron, Ali Can et al. · IEEE Reviews in Biomedical Engineering Open access 2009 2,075
40 Quantification of histochemical staining by color deconvolution. Arnout C. C. Ruifrok, D. A. Johnston · PubMed Aug 2001 2,072
41 U-Net: deep learning for cell counting, detection, and morphometry Thorsten Falk et al. · Nature Methods 4 Dec 2018 2,057
42 Deep Learning for Health Informatics Daniele Ravì, Charence Wong, Fani Deligianni et al. · IEEE Journal of Biomedical and Health Informatics Open access 29 Dec 2016 2,025
43 GAN-based synthetic medical image augmentation for increased CNN performance in liver lesion classification Maayan Frid-Adar, Idit Diamant, Eyal Klang et al. · Neurocomputing Open access 21 Sep 2018 1,987
44 U-Net and Its Variants for Medical Image Segmentation: A Review of Theory and Applications Nahian Alam Siddique, Sidike Paheding, Colin P. Elkin et al. · IEEE Access Open access 2021 1,962
45 Diagnostic Performance of Digital versus Film Mammography for Breast-Cancer Screening Etta D. Pisano, Constantine A. Gatsonis, Edward R. Hendrick et al. · New England Journal of Medicine Open access 16 Sep 2005 1,945
46 A comparison of deep learning performance against health-care professionals in detecting diseases from medical imaging: a systematic review and meta-analysis Xiaoxuan Liu, Livia Faes, Aditya U. Kale et al. · The Lancet Digital Health ReviewOpen access 25 Sep 2019 1,936
47 Deformable models in medical image analysis: a survey Tim McInerney, Demetri Terzopoulos · Medical Image Analysis Jun 1996 1,921
48 Generative adversarial network in medical imaging: A review Yi Xin, Ekta Walia, Paul Babyn · Medical Image Analysis Open access 31 Aug 2019 1,911
49 Artificial intelligence in cancer imaging: Clinical challenges and applications Wenya Linda Bi, Ahmed Hosny, Matthew B. Schabath et al. · CA A Cancer Journal for Clinicians Open access 5 Feb 2019 1,886
50 Causability and explainability of artificial intelligence in medicine Andreas Holzinger, Georg Langs, Helmut Denk et al. · Wiley Interdisciplinary Reviews Data Mining and Knowledge Discovery Open access 2 Apr 2019 1,872

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.