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Most cited papers in Aldose Reductase and Taurine

What are the most cited papers in Aldose Reductase and Taurine?

The most cited paper in Aldose Reductase and Taurine is "Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage" (Takeshi Nishikawa, Diane Edelstein, Xue Liang Du et al., 2000), with 4,302 citations. Next come "Bilirubin Is an Antioxidant of Possible Physiological Importance" (3,543) and "The Carbon Monoxide-binding Pigment of Liver Microsomes" (3,499).

Showing 50 of 100 papers. Every paper with more than 457 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage Takeshi Nishikawa, Diane Edelstein, Xue Liang Du et al. · Nature Apr 2000 4,302
2 Bilirubin Is an Antioxidant of Possible Physiological Importance Roland Stocker, Yorihiro Yamamoto, Antony F. McDonagh et al. · Science 27 Feb 1987 3,543
3 The Carbon Monoxide-binding Pigment of Liver Microsomes Tsuneo Omura, Ryo Sato · Journal of Biological Chemistry Open access Jul 1964 3,499
4 The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas Tomasz Szkudelski · Physiological Research Open access 2001 2,884
5 Physiological actions of taurine Ryan J. Huxtable · Physiological Reviews 1992 2,617
6 Oxidative stress as a mediator of apoptosis Thomas M. Buttke, Paul A. Sandstrom · Immunology Today 1994 2,199
7 Transcriptional regulation by calcium, calcineurin, and NFAT Patrick G. Hogan, Lin Chen, Julie Nardone et al. · Genes & Development Open access 15 Sep 2003 2,019
8 A Transgenic Model of Visceral Obesity and the Metabolic Syndrome Hiroaki Masuzaki, J. Paterson, Hiroshi Shinyama et al. · Science 7 Dec 2001 1,767
9 Polyamine metabolism and function Anthony E. Pegg, Peter P. McCann · American Journal of Physiology-Cell Physiology Nov 1982 1,664
10 Carbonic anhydrase inhibitors Claudiu Trandafir Supuran, Andrea Scozzafava, Angela Casini · Medicinal Research Reviews 13 Dec 2002 1,450
11 Arginine metabolism and nutrition in growth, health and disease Guoyao Wu, Fuller W. Bazer, Teresa A. Davis et al. · Amino Acids Open access 22 Nov 2008 1,394
12 Triggering and modulation of apoptosis by oxidative stress Joya Chandra, Afshin Samali, Sten Orrenius · Free Radical Biology and Medicine Aug 2000 1,334
13 Short-chain dehydrogenases/reductases (SDR) Hans Jörnvall, Bengt L Persson, Maria Krook et al. · Biochemistry 9 May 1995 1,268
14 Mechanisms of Cell Protection by Heme Oxygenase-1 Raffaella Gozzelino, Viktória Jeney, Miguel Parreira Soares · The Annual Review of Pharmacology and Toxicology Review 8 Jan 2010 1,251
15 Nitric Oxide Scavenging by Curcuminoids Sreejayan, Mahadev Rao · Journal of Pharmacy and Pharmacology 1997 1,137
16 Biliverdin reductase: A major physiologic cytoprotectant David E. Barañano, Mahil Rao, Christopher D. Ferris et al. · Proceedings of the National Academy of Sciences Open access 27 Nov 2002 1,101
17 Increased Expression of Genes Converting Adrenal Androgens to Testosterone in Androgen-Independent Prostate Cancer Michael Stanbrough, Glenn J. Bubley, Kenneth N. Ross et al. · Cancer Research Open access Mar 2006 1,088
18 Oxygen free radicals in ischemic acute renal failure in the rat. Mark S. Paller, J. R. Hoidal, TF Ferris · Journal of Clinical Investigation Open access Oct 1984 1,077
19 The Role of Advanced Glycation End Products in Progression and Complications of Diabetes Su‐Yen Goh, Mark Emmanuel Cooper · The Journal of Clinical Endocrinology & Metabolism 8 Jan 2008 995
20 Urinary Bladder Contraction and Relaxation: Physiology and Pathophysiology Karl‐Erik Andersson, Anders Arner · Physiological Reviews Review Jul 2004 953
21 Toxicology of Hydrogen Sulfide R. J. Reiffenstein, William C. Hulbert, Steven Roth · The Annual Review of Pharmacology and Toxicology Apr 1992 940
22 Nitric oxide synthase: Aspects concerning structure and catalysis Michael A. Marletta · Cell Open access Sep 1994 863
23 Soluble Adenylyl Cyclase as an Evolutionarily Conserved Bicarbonate Sensor Yanqiu Chen, Martin J. Cann, Tatiana N. Litvin et al. · Science Open access 28 Jul 2000 855
24 Antioxidant Systems and Oxidative Stress in the Testes R. John Aitken, Shaun D. Roman · Oxidative Medicine and Cellular Longevity Open access 2008 839
25 Activation of the Receptor for Advanced Glycation End Products Triggers a p21 -dependent Mitogen-activated Protein Kinase Pathway Regulated by Oxidant Stress Harry M. Lander, James M. Tauras, Jason S. Ogiste et al. · Journal of Biological Chemistry Open access Jul 1997 816
26 Cellular Response to Hyperosmotic Stresses Maurice B. Burg, Joan D. Ferraris, Natalia I. Dmitrieva · Physiological Reviews Review Oct 2007 812
27 Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitination Yasuko Murakami, Senya Matsufuji, Takaaki Kameji et al. · Nature Dec 1992 794
28 Stress-Activated Cap'n'collar Transcription Factors in Aging and Human Disease Gerasimos P. Sykiotis, Dirk Bohmann · Science Signaling Open access 9 Mar 2010 790
29 Partners in transcription: NFAT and AP-1 Fernando Macián, Cristina López‐Rodríguez, Anjana Rao · Oncogene 30 Apr 2001 780
30 Oxidative Stress, Antioxidants, and Animal Function J.K. Miller, Ewa Brzezińska-Ślebodzińska, F.C. Madsen · Journal of Dairy Science Open access Sep 1993 771
31 Vitamin C Carole L. Linster, Emile Van Schaftingen · FEBS Journal Open access 6 Dec 2006 762
32 Amine synthesis in rapidly growing tissues: ornithine decarboxylase activity in regenerating rat liver, chick embryo, and various tumors. D Russell, Solomon H. Snyder · Proceedings of the National Academy of Sciences Open access Aug 1968 750
33 Na+/H+ exchange and growth factor-induced cytosolic pH changes. Role in cellular proliferation Sergio Grinstein, Daniela Rotin, Mike J. Mason · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes 1989 744
34 The Regulation of Rat Liver Xanthine Oxidase Fiorenzo Stirpe, E. Della Corte, Elisa Lorenzoni · Journal of Biological Chemistry Open access Jul 1969 733
35 PURIFICATION OF AMINE OXIDASE FROM BEEF PLASMA Celia White Tabor, Herbert Tabor, Sanford M. Rosenthal · Journal of Biological Chemistry Open access Jun 1954 726
36 The oxidative inactivation of mitochondrial electron transport chain components and ATPase. Yong Zhang, Olivier Marcillat, Cecilia Giulivi et al. · Journal of Biological Chemistry Open access Sep 1990 715
37 Characterization of the enzymic capacity for cysteine desulphhydration in liver and kidney of the rat Martha H. Stipanuk, P W Beck · Biochemical Journal Open access 15 Aug 1982 713
38 Swelling-induced release of glutamate, aspartate, and taurine from astrocyte cultures HK Kimelberg, SK Goderie, Susan M. Higman et al. · Journal of Neuroscience Open access May 1990 694
39 Mechanisms by Which Dehydration May Lead to Chronic Kidney Disease Carlos A. Roncal-Jiménez, Miguel Angel Lanaspa, Thomas Jensen et al. · Annals of Nutrition and Metabolism Open access 2015 694
40 Reduced beta-cell mass and expression of oxidative stress-related DNA damage in the islet of Japanese Type II diabetic patients Hiroyasu Sakuraba, Hiroki Mizukami, Nobuo Yagihashi et al. · Diabetologia Open access 2002 687
41 Intracellular Organic Osmolytes: Function and Regulation Maurice B. Burg, Joan D. Ferraris · Journal of Biological Chemistry Open access 7 Feb 2008 680
42 Diabetes and Kidney Disease: Role of Oxidative Stress Jay C. Jha, Claudine Banal, Bryna S.M. Chow et al. · Antioxidants and Redox Signaling Open access 24 Feb 2016 678
43 The Role of Oxidative Stress and Hypoxia in Pancreatic Beta-Cell Dysfunction in Diabetes Mellitus Philipp A. Gerber, Guy A. Rutter · Antioxidants and Redox Signaling Open access 26 May 2016 664
44 Polyamines as Targets for Therapeutic Intervention L J Marton, A E Pegg · The Annual Review of Pharmacology and Toxicology Apr 1995 622
45 Molecular Biology of the 3β-Hydroxysteroid Dehydrogenase/Δ5-Δ4 Isomerase Gene Family Jacques Simard, Marie‐Louise Ricketts, Sébastien Gingras et al. · Endocrine Reviews 4 Jan 2005 622
46 Contribution of Polyol Pathway to Diabetes-Induced Oxidative Stress Stephen S.M. Chung, Eric C.M. Ho, Karen S.L. Lam et al. · Journal of the American Society of Nephrology Aug 2003 612
47 Comparative anatomy of the aldo–keto reductase superfamily Joseph M. Jez, M. J. Bennett, Brian P. Schlegel et al. · Biochemical Journal Open access 15 Sep 1997 612
48 Physiology and pathophysiology of intestinal absorption WF Caspary · American Journal of Clinical Nutrition 1992 609
49 Retinal Degeneration Associated with Taurine Deficiency in the Cat K. C. Hayes, Richard E. Carey, Susan Y. Schmidt · Science 30 May 1975 596
50 Review: taurine: a "very essential" amino acid. Harris Ripps, Wen‐Hui Shen · PubMed Open access 2012 593

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.