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Topic · Cell Biology

Aldose Reductase and Taurine

Aldose Reductase and Taurine is a research topic within Cell Biology. Science Explorer counts 12k research works in it since 1950. 10.0% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the cellular response to osmotic stress, with a focus on the role of aldose reductase, taurine, and the aldo-keto reductase superfamily in conditions such as diabetes, inflammation, and oxidative stress. It also delves into the implications for mitochondrial function, neuroprotection, and cardiovascular health.

  • Aldose Reductase
  • Taurine
  • Oxidative Stress
  • Diabetes
  • Aldo-Keto Reductase Superfamily
  • Hyperosmotic Stress
  • Inflammation
  • Mitochondrial Function
  • Neuroprotection
  • Cardiovascular Function
Research works
12k
fractional, since 1950
In the world top 10%
1.1k
per year above
Top-10% rate
10.0%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+6%
the tick is no change
Largest producer
China
46% of the 10 largest, 2022-now

Which countries lead Aldose Reductase and Taurine research?

By volume, China and the United States publish the most (419 and 160 works in 2022-now).

By volume, 2022-now

  1. 1 China 419 works
  2. 2 United States 160 works
  3. 3 India 70 works
  4. 4 Japan 61 works
  5. 5 Türkiye 47 works
  6. 6 Iran 33 works
  7. 7 South Korea 32 works
  8. 8 Egypt 30 works
  9. 9 Italy 28 works
  10. 10 Germany 27 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 46.2%United States: 17.6%India: 7.7%Japan: 6.7%6 others listed: 21.8%46%largest
China419 · 46.2%United States160 · 17.6%India70 · 7.7%Japan61 · 6.7%6 others listed198 · 21.8%

Shares of the rows listed above, not of the whole node.

Which institutions lead Aldose Reductase and Taurine research?

By volume in 2022-now, Wenzhou Medical University publishes the most Aldose Reductase and Taurine research, followed by Chinese Academy of Sciences and Sun Yat-sen University.

Who are the leading researchers in Aldose Reductase and Taurine?

The most-cited researchers publishing on Aldose Reductase and Taurine include Luigi Ferrucci and Tien Yin Wong.

  1. 1 Luigi Ferrucci United States 281k citations
  2. 2 Tien Yin Wong Singapore 237k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Aldose Reductase and Taurine?

The most cited paper in Aldose Reductase and Taurine is "Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage" (Takeshi Nishikawa, Diane Edelstein, Xue Liang Du et al., 2000), with 4,302 citations. Next come "Bilirubin Is an Antioxidant of Possible Physiological Importance" (3,543) and "The Carbon Monoxide-binding Pigment of Liver Microsomes" (3,499).

Most cited papers
#PaperReleasedCitations
1 Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage Takeshi Nishikawa, Diane Edelstein, Xue Liang Du et al. · Nature Apr 2000 4,302
2 Bilirubin Is an Antioxidant of Possible Physiological Importance Roland Stocker, Yorihiro Yamamoto, Antony F. McDonagh et al. · Science 27 Feb 1987 3,543
3 The Carbon Monoxide-binding Pigment of Liver Microsomes Tsuneo Omura, Ryo Sato · Journal of Biological Chemistry Open access Jul 1964 3,499
4 The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas Tomasz Szkudelski · Physiological Research Open access 2001 2,884
5 Physiological actions of taurine Ryan J. Huxtable · Physiological Reviews 1992 2,617
All 100 most cited papers, with filters and sorting

Where is Aldose Reductase and Taurine research done?

The largest centres of Aldose Reductase and Taurine research in 2022-now are Beijing (China), Shanghai (China), Guangzhou (China) and Nanjing (China). Among places with at least 20 works in it, it is an unusually large share of all research in Guangzhou.

Largest cities, 2022-now

  1. 1 BeijingChina 45 works
  2. 2 ShanghaiChina 25 works
  3. 3 GuangzhouChina 24 works
  4. 4 NanjingChina 18 works
  5. 5 HangzhouChina 17 works
  6. 6 WuhanChina 13 works
  7. 7 ChongqingChina 12 works
  8. 8 ChengduChina 12 works
  9. 9 TokyoJapan 11 works
  10. 10 ChangshaChina 11 works

Where it is the local speciality

  1. GuangzhouCN · 24.4 works2.4×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Aldose Reductase and Taurine than the world average.

See Aldose Reductase and Taurine on the map

Where is the best place to study Aldose Reductase and Taurine?

Among universities, judged by research, Wenzhou Medical University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Wenzhou Medical UniversityChina 10.09.5%16.1×8 +46.5%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Aldose Reductase and Taurine, country by country

Is Aldose Reductase and Taurine research growing?

Output in 2022-2025 was 6% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Aldose Reductase and Taurine.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Aldose Reductase and Taurine as a percentage of every work published that year, 0.0045% in 2024.

still counting0.020%0.040%Aldose Reductase and Taurine0.0052% in 202519801990200020102020

Fractional works of Aldose Reductase and Taurine over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Aldose Reductase and Taurine10.7% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

Discussion

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