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Topic · Cell Biology

Proteoglycans and glycosaminoglycans research

Proteoglycans and glycosaminoglycans research is a research topic within Cell Biology. Science Explorer counts 30k research works in it since 1950. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the role of extracellular matrix components such as hyaluronan, proteoglycans, and heparan sulfate in regulating cell signaling, synaptic plasticity, inflammation, and angiogenesis. It delves into the molecular interactions and functions of these matrix molecules in various biological processes.

  • Hyaluronan
  • Proteoglycans
  • Heparan Sulfate
  • CD44
  • Cell Signaling
  • Glycosaminoglycans
  • Toll-like Receptors
  • Synaptic Plasticity
  • Inflammation
  • Angiogenesis
Research works
30k
fractional, since 1950
In the world top 10%
3k
per year above
Top-10% rate
9.9%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-3%
the tick is no change
Largest producer
China
38% of the 10 largest, 2022-now
Proteoglycans and glycosaminoglycans research

Which countries lead Proteoglycans and glycosaminoglycans research research?

By volume, China and the United States publish the most (1k and 610 works in 2022-now).

By volume, 2022-now

  1. 1 China 1k works
  2. 2 United States 610 works
  3. 3 Japan 258 works
  4. 4 India 162 works
  5. 5 Germany 140 works
  6. 6 Italy 111 works
  7. 7 United Kingdom 90 works
  8. 8 France 88 works
  9. 9 South Korea 84 works
  10. 10 Spain 63 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 38.4%United States: 23.4%Japan: 9.9%India: 6.2%6 others listed: 22.1%38%largest
China1,001 · 38.4%United States610 · 23.4%Japan258 · 9.9%India162 · 6.2%6 others listed576 · 22.1%

Shares of the rows listed above, not of the whole node.

Which institutions lead Proteoglycans and glycosaminoglycans research research?

By volume in 2022-now, Centre National de la Recherche Scientifique publishes the most Proteoglycans and glycosaminoglycans research research, followed by Shanghai Jiao Tong University and Chinese Academy of Sciences.

By volume, 2022-now

  1. 1 Centre National de la Recherche ScientifiqueFrance 28 works
  2. 2 Shanghai Jiao Tong UniversityChina 25 works
  3. 3 Chinese Academy of SciencesChina 25 works
  4. 4 Sichuan UniversityChina 23 works
  5. 5 Peking UniversityChina 23 works
  6. 6 Shandong UniversityChina 20 works
  7. 7 Sun Yat-sen UniversityChina 20 works
  8. 8 Russian Academy of SciencesRussia 20 works
  9. 9 Harvard UniversityUnited States 19 works
  10. 10 Jiangnan UniversityChina 17 works

Who are the leading researchers in Proteoglycans and glycosaminoglycans research?

The most-cited researchers publishing on Proteoglycans and glycosaminoglycans research include Eric S. Lander, Jun Wang and Peter Jüni.

  1. 1 Eric S. Lander United States 524k citations
  2. 2 Jun Wang China 340k citations
  3. 3 Peter Jüni Switzerland 303k citations
  4. 4 Róbert Langer United States 303k citations
  5. 5 Robert A. Weinberg United States 301k citations
  6. 6 Matthew M. Meyerson United States 280k citations
  7. 7 Reza Malekzadeh Iran 278k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Proteoglycans and glycosaminoglycans research?

The most cited paper in Proteoglycans and glycosaminoglycans research is "New method for quantitative determination of uronic acids" (Nelly Blumenkrantz, GUSTAV ASBOE‐HANSEN, 1973), with 7,161 citations. Next come "Regeneration beyond the glial scar" (3,151) and "Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis." (3,129).

Most cited papers
#PaperReleasedCitations
1 New method for quantitative determination of uronic acids Nelly Blumenkrantz, GUSTAV ASBOE‐HANSEN · Analytical Biochemistry Aug 1973 7,161
2 Regeneration beyond the glial scar Jerry Silver, Jared H. Miller · Nature reviews. Neuroscience Review 20 Jan 2004 3,151
3 Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Harold F. Dvorak, Lawrence F. Brown, Michael J. Detmar et al. · PubMed Open access May 1995 3,129
4 The extracellular matrix: A dynamic niche in cancer progression Pengfei Lu, Valerie Marie Weaver, Zena Werb · The Journal of Cell Biology Open access 20 Feb 2012 3,079
5 Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis Gabriele Bergers, Rolf A. Brekken, Gerald McMahon et al. · Nature Cell Biology Open access 20 Sep 2000 2,809
All 100 most cited papers, with filters and sorting

Where is Proteoglycans and glycosaminoglycans research research done?

The largest centres of Proteoglycans and glycosaminoglycans research research in 2022-now are Beijing (China), Shanghai (China), Tokyo (Japan) and Guangzhou (China). Among places with at least 20 works in it, it is an unusually large share of all research in Wuxi.

Largest cities, 2022-now

  1. 1 BeijingChina 113 works
  2. 2 ShanghaiChina 80 works
  3. 3 TokyoJapan 63 works
  4. 4 GuangzhouChina 61 works
  5. 5 JinanChina 43 works
  6. 6 NanjingChina 43 works
  7. 7 Xi'anChina 37 works
  8. 8 SeoulSouth Korea 37 works
  9. 9 HangzhouChina 35 works
  10. 10 QingdaoChina 35 works

Where it is the local speciality

  1. WuxiCN · 22.5 works6.8×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Proteoglycans and glycosaminoglycans research than the world average.

See Proteoglycans and glycosaminoglycans research on the map

Where is the best place to study Proteoglycans and glycosaminoglycans research?

Among universities, judged by research, Harvard University, Jiangnan University and Sichuan University score highest, combining citation excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%30%mean 16.64%fractional works in this field (log) →share of work in the world top 10% →Southern Medical Uni…Jiangnan UniversitySichuan UniversityHarvard University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Citation excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Harvard UniversityUnited States 70.518.6%1.9×18 -15.9%
2Jiangnan UniversityChina 69.420.1%9.3×17 +61.5%
3Sichuan UniversityChina 67.519.7%3.4×23 -0.6%
4Southern Medical UniversityChina 67.022.4%8.0×15 +51.6%
5Shanghai Jiao Tong UniversityChina 63.315.1%2.9×25 -9.0%
6Shandong UniversityChina 60.914.0%5.1×20 +39.9%
7Wenzhou Medical UniversityChina 59.925.3%8.0×12 -0.5%
8Peking UniversityChina 55.46.1%3.7×23 +43.4%
9Nanjing Medical UniversityChina 51.013.2%6.0×16 +13.0%
10Sun Yat-sen UniversityChina 49.911.9%3.2×20 -8.7%

Universities only. The score blends citation excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Proteoglycans and glycosaminoglycans research, country by country

Is Proteoglycans and glycosaminoglycans research research growing?

Output in 2022-2025 was 3% lower than in 2018-2021, peaking in 2025.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Proteoglycans and glycosaminoglycans research as a percentage of every work published that year, 0.013% in 2024.

still counting0.025%0.050%0.075%Proteoglycans and glycosaminoglycans research0.015% in 202519801990200020102020

Fractional works of Proteoglycans and glycosaminoglycans research over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Proteoglycans and glycosaminoglycans research9.9% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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