Endoplasmic Reticulum Stress and Disease
Endoplasmic Reticulum Stress and Disease is a research topic within Cell Biology. Science Explorer counts 34k research works in it since 1950. 27.8% of them reached the world's top 10% most cited for their field and year.
This cluster of papers focuses on the molecular mechanisms, regulation, and consequences of endoplasmic reticulum (ER) stress and the unfolded protein response (UPR). It explores the role of ER stress in various diseases such as diabetes, cancer, neurodegenerative diseases, and liver disease, highlighting its impact on cell fate decisions, protein folding, oxidative stress, and apoptosis. The cluster also delves into the involvement of UPR pathways, chaperones, and the interplay between ER stress and inflammation.
- Endoplasmic Reticulum
- Stress
- Unfolded Protein Response
- ER Stress
- Cell Death
- Protein Folding
- UPR Pathways
- Oxidative Stress
- Apoptosis
- Chaperones
- Research works
- 34k fractional, since 1950
- In the world top 10%
- 9.3k per year above
- Top-10% rate
- 27.8% share of its works in the world top 10%
- Growth, 2013–17 → 2018–22
- +11% the tick is no change
Which countries lead Endoplasmic Reticulum Stress and Disease research?
By volume, China and the United States publish the most (2k and 1.2k works in 2022–2025).
By volume, 2022–2025
- 1 China 2k works
- 2 United States 1.2k works
- 3 Japan 286 works
- 4 India 228 works
- 5 Germany 214 works
- 6 South Korea 168 works
- 7 United Kingdom 164 works
- 8 Italy 147 works
- 9 France 133 works
- 10 Canada 105 works
How concentrated that is
The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.
Shares of the rows listed above, not of the whole node.
Which institutions lead Endoplasmic Reticulum Stress and Disease research?
By volume in 2022–2025, Sun Yat-sen University publishes the most Endoplasmic Reticulum Stress and Disease research, followed by Chinese Academy of Medical Sciences & Peking Union Medical College and Huazhong University of Science and Technology.
By volume, 2022–2025
- 1 Sun Yat-sen UniversityChina 27 works
- 2 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 27 works
- 3 Huazhong University of Science and TechnologyChina 24 works
- 4 Shanghai Jiao Tong UniversityChina 24 works
- 5 University of MichiganUnited States 23 works
- 6 Harvard UniversityUnited States 21 works
- 7 Zhejiang UniversityChina 20 works
- 8 Wuhan UniversityChina 20 works
- 9 Central South UniversityChina 20 works
- 10 Chinese Academy of SciencesChina 19 works
Who are the leading researchers in Endoplasmic Reticulum Stress and Disease?
The most-cited researchers publishing on Endoplasmic Reticulum Stress and Disease include Guido Kroemer.
- 1 Guido Kroemer France 4.2k citations
Ranked by citations received across their whole record, among researchers with at least three works on this topic.
Where is Endoplasmic Reticulum Stress and Disease research done?
The largest centres of Endoplasmic Reticulum Stress and Disease research in 2022–2025 are Beijing (China), Shanghai (China), Guangzhou (China) and Wuhan (China).
Where is the best place to study Endoplasmic Reticulum Stress and Disease?
Among universities, judged by research, Zunyi Medical University, China Pharmaceutical University and Guangxi Medical University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.
One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.
| # | University | Score | Top 10% | Specialisation | Works | Growth |
|---|---|---|---|---|---|---|
| 1 | Zunyi Medical UniversityChina | 54.3 | 41.5% | 12.2× | 10 | — |
| 2 | China Pharmaceutical UniversityChina | 54.2 | 41.1% | 8.0× | 10 | +157.3% |
| 3 | Guangxi Medical UniversityChina | 53.6 | 28.0% | 10.2× | 10 | +276.4% |
| 4 | Anhui Medical UniversityChina | 53.3 | 25.9% | 11.2× | 18 | +40.5% |
| 5 | Dalian Medical UniversityChina | 53.3 | 28.0% | 13.1× | 14 | +98.2% |
| 6 | Wuhan UniversityChina | 50.4 | 38.7% | 3.0× | 20 | +134.8% |
| 7 | Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina | 50.3 | 35.0% | 5.1× | 27 | -6.2% |
| 8 | Sun Yat-sen UniversityChina | 50.1 | 34.4% | 3.1× | 27 | +80.7% |
| 9 | Air Force Medical UniversityChina | 49.7 | 39.9% | 11.0× | 10 | -16.0% |
| 10 | Harvard UniversityUnited States | 48.5 | 40.0% | 3.1× | 22 | -6.0% |
Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.
Is Endoplasmic Reticulum Stress and Disease research growing?
Output in 2018–2022 was 11% higher than in 2013–2017, peaking in 2025. The fastest-growing topics are Endoplasmic Reticulum Stress and Disease.
The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.
Which topics inside it are moving
Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.